Molecular Therapy - Nucleic Acids is an online-only, open access journal publishing high quality basic, translational, and clinical research and cutting-edge reviews and commentaries targeted to the advances in oligonucleotide - and gene-based therapies. The journal has an Impact Factor of 4.512.
Explore the benefits of submitting your next research article: http://bit.ly/1vUsltu | | | | | | Editorial | Top | | Adeno-associated Vector Toxicity—To Be or Not to Be?Hildegard Büning and Manfred Schmidt Mol Ther 2015 23: 1673-1675; 10.1038/mt.2015.182 Full Text | | In This Issue | Top | | In This IssueMol Ther 2015 23: 1676; 10.1038/mt.2015.183 Full Text | | Research Highlights | Top | | Research HighlightsMol Ther 2015 23: 1677; 10.1038/mt.2015.184 Full Text | | Commentary | Top | | Gene Editing and Germ-line Intervention: The Need for Novel Responses to Novel TechnologiesCourtney Addison and Samuel Taylor-Alexander Mol Ther 2015 23: 1678-1680; 10.1038/mt.2015.185 Full Text | | Original Articles | Top | | Long-term Improvements in Lifespan and Pathology in CNS and PNS After BMT Plus One Intravenous Injection of AAVrh10-GALC in Twitcher MiceMohammad A Rafi, Han Zhi Rao, Paola Luzi and David A Wenger Mol Ther 2015 23: 1681-1690; advance online publication, September 2, 2015; 10.1038/mt.2015.145 Abstract | Full Text | | | | Intracisternal Gtf2i Gene Therapy Ameliorates Deficits in Cognition and Synaptic Plasticity of a Mouse Model of Williams–Beuren SyndromeCristina Borralleras, Ignasi Sahun, Luis A Pérez-Jurado and Victoria Campuzano Mol Ther 2015 23: 1691-1699; advance online publication, July 28, 2015; 10.1038/mt.2015.130 Abstract | Full Text | | | | Pharmacological Modulation of Photoreceptor Outer Segment Degradation in a Human iPS Cell Model of Inherited Macular DegenerationRuchira Singh, David Kuai, Karina E Guziewicz, Jackelyn Meyer, Molly Wilson, Jianfeng Lu, Molly Smith, Eric Clark, Amelia Verhoeven, Gustavo D Aguirre and David M Gamm Mol Ther 2015 23: 1700-1711; advance online publication, August 24, 2015; 10.1038/mt.2015.141 Abstract | Full Text | | | | AAV2/1 CD74 Gene Transfer Reduces β-amyloidosis and Improves Learning and Memory in a Mouse Model of Alzheimer’s DiseaseMTOPENTomomi Kiyota, Gang Zhang, Christine M Morrison, Megan E Bosch, Robert A Weir, Yaman Lu, Weiguo Dong and Howard E Gendelman Mol Ther 2015 23: 1712-1721; advance online publication, July 31, 2015; 10.1038/mt.2015.142 Abstract | Full Text | | | | A HER2-specific Modified Fc Fragment (Fcab) Induces Antitumor Effects Through Degradation of HER2 and ApoptosisMTOPENKin-Mei Leung, Sarah Batey, Robert Rowlands, Samine J Isaac, Phil Jones, Victoria Drewett, Joana Carvalho, Miguel Gaspar, Sarah Weller, Melanie Medcalf, Mateusz M Wydro, Robert Pegram, Geert C Mudde, Anton Bauer, Kevin Moulder, Max Woisetschläger, Mihriban Tuna, John S Haurum and Haijun Sun Mol Ther 2015 23: 1722-1733; advance online publication, August 3, 2015; 10.1038/mt.2015.127 Abstract | Full Text | | | | A Lentiviral Vector Allowing Physiologically Regulated Membrane-anchored and Secreted Antibody Expression Depending on B-cell Maturation StatusFloriane Fusil, Sara Calattini, Fouzia Amirache, Jimmy Mancip, Caroline Costa, Justin B Robbins, Florian Douam, Dimitri Lavillette, Mansun Law, Thierry Defrance, Els Verhoeyen and François-Loïc Cosset Mol Ther 2015 23: 1734-1747; advance online publication, August 18, 2015; 10.1038/mt.2015.148 Abstract | Full Text | | | | miR-221/222 Are Involved in Response to Sunitinib Treatment in Metastatic Renal Cell CarcinomaHeba W Z Khella, Henriett Butz, Qiang Ding, Fabio Rotondo, Kenneth R Evans, Peter Kupchak, Moyez Dharsee, Ashraf Latif, Maria D Pasic, Evi Lianidou, Georg A Bjarnason and George M Yousef Mol Ther 2015 23: 1748-1758; advance online publication, July 23, 2015; 10.1038/mt.2015.129 Abstract | Full Text | | | | Huntingtin Haplotypes Provide Prioritized Target Panels for Allele-specific Silencing in Huntington Disease Patients of European AncestryChris Kay, Jennifer A Collins, Niels H Skotte, Amber L Southwell, Simon C Warby, Nicholas S Caron, Crystal N Doty, Betty Nguyen, Annamaria Griguoli, Colin J Ross, Ferdinando Squitieri and Michael R Hayden Mol Ther 2015 23: 1759-1771; advance online publication, July 23, 2015; 10.1038/mt.2015.128 Abstract | Full Text | | | | Delivery of siRNA Using CXCR4-targeted Nanoparticles Modulates Tumor Microenvironment and Achieves a Potent Antitumor Response in Liver CancerJia-Yu Liu, Tsaiyu Chiang, Chun-Hung Liu, Guann-Gen Chern, Ts-Ting Lin, Dong-Yu Gao and Yunching Chen Mol Ther 2015 23: 1772-1782; advance online publication, August 17, 2015; 10.1038/mt.2015.147 Abstract | Full Text | | | | Suppression of IL-7-dependent Effector T-cell Expansion by Multipotent Adult Progenitor Cells and PGE2James L Reading, Bart Vaes, Caroline Hull, Shereen Sabbah, Thomas Hayday, Nancy S Wang, Anthony DiPiero, Nicholas A Lehman, Jen M Taggart, Fiona Carty, Karen English, Jef Pinxteren, Robert Deans, Anthony E Ting and Timothy I M Tree Mol Ther 2015 23: 1783-1793; advance online publication, July 28, 2015; 10.1038/mt.2015.131 Abstract | Full Text | | Erratum | Top | | Erratum to “A HER2-specific Modified Fc Fragment (Fcab) Induces Antitumor Effects Through Degradation of HER2 and Apoptosis”Mol Ther 2015 23: 1794; 10.1038/mt.2015.163 Full Text | | Corrigendum | Top | | Corrigendum to “Disruption of KATP Channel Expression in Skeletal Muscle by Targeted Oligonucleotide Delivery Promotes Activity-linked Thermogenesis”Mol Ther 2015 23: 1794; 10.1038/mt.2015.186 Full Text | | | | Please note that you need to be a subscriber or site-license holder to enjoy full-text access to Molecular Therapy. 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