Wednesday, July 1, 2015

Nature Communications - 01 July 2015

 
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01 July 2015 
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PPL2ab neurons restore sexual responses in aged Drosophila males through dopamine OPEN
Shu-Yun Kuo, Chia-Lin Wu, Min-Yen Hsieh, Chen-Ta Lin, Rong-Kun Wen, Lien-Cheng Chen, Yu-Hui Chen, Yhu-Wei Yu, Horng-Dar Wang, Yi-Ju Su, Chun-Ju Lin, Cian-Yi Yang, Hsien-Yu Guan, Pei-Yu Wang, Tsuo-Hung Lan and Tsai-Feng Fu
We currently lack a detailed understanding of the neurobiological basis for the decline of male sexual desire with age. Here the authors demonstrate that restoring impaired dopaminergic signalling in a specific cluster of neurons in the Drosophila brain increases sexual behaviour in ageing male flies.
30 June 2015 | doi: 10.1038/ncomms8490
Biological Sciences  Neuroscience 

Early emergence of Yersinia pestis as a severe respiratory pathogen OPEN
Daniel L. Zimbler, Jay A. Schroeder, Justin L. Eddy and Wyndham W. Lathem
Yersinia pestis, which evolved from a gastrointestinal pathogen, causes pneumonic and bubonic plague. Here Zimbler et al. show that the gain of a single protein enabled Y. pestis to first cause pneumonic plague, and one amino-acid change in the same protein then allowed the bacteria to efficiently cause bubonic plague.
30 June 2015 | doi: 10.1038/ncomms8487
Biological Sciences  Evolution  Microbiology 

Metabolic and metagenomic outcomes from early-life pulsed antibiotic treatment OPEN
Yael R. Nobel, Laura M. Cox, Francis F. Kirigin, Nicholas A. Bokulich, Shingo Yamanishi, Isabel Teitler, Jennifer Chung, Jiho Sohn, Cecily M. Barber, David S. Goldfarb, Kartik Raju, Sahar Abubucker, Yanjiao Zhou, Victoria E. Ruiz, Huilin Li, Makedonka Mitreva, Alexander V. Alekseyenko, George M. Weinstock, Erica Sodergren and Martin J. Blaser et al.
The potential recovery of the human gut microbiota after an antibiotic treatment, and its effects on our health, are poorly understood. Here, the authors use a mouse model mimicking paediatric antibiotic use to shed new light into these processes.
30 June 2015 | doi: 10.1038/ncomms8486
Biological Sciences  Ecology  Microbiology 

High rates of anaerobic methane oxidation in freshwater wetlands reduce potential atmospheric methane emissions
K. E. A. Segarra, F. Schubotz, V. Samarkin, M. Y. Yoshinaga, K-U Hinrichs and S. B. Joye
Freshwater wetlands are among the largest natural sources of methane to the atmosphere. Here, the authors report rates of anaerobic methane oxidation which rival those in marine environments, highlighting the importance of a long-overlooked anaerobic methane sink.
30 June 2015 | doi: 10.1038/ncomms8477
Earth Sciences  Biochemistry 

Vibrational spectroscopy at electrolyte/electrode interfaces with graphene gratings OPEN
Ya-Qing Bie, Jason Horng, Zhiwen Shi, Long Ju, Qin Zhou, Alex Zettl, Dapeng Yu and Feng Wang
Understanding of electrolyte-electrode interfaces is limited due to the lack of suitable probing techniques. Here, the authors present a vibrational spectroscopy based on graphene gratings, which enables sensitive and interface-specific detection of molecular vibrations at electrolyte-electrode interfaces.
30 June 2015 | doi: 10.1038/ncomms8593
Chemical Sciences  Nanotechnology  Physical chemistry 

Variable Holocene deformation above a shallow subduction zone extremely close to the trench OPEN
Kaustubh Thirumalai, Frederick W. Taylor, Chuan-Chou Shen, Luc L. Lavier, Cliff Frohlich, Laura M. Wallace, Chung-Che Wu, Hailong Sun and Alison K. Papabatu
Information regarding tectonic motion from before instrumental records can be found from palaeoshorelines and the reconstruction of sea level from observations. Here, the authors study corals uplifted by past earthquakes near the Solomon Islands and assess the Holocene deformation that took place there.
30 June 2015 | doi: 10.1038/ncomms8607
Earth Sciences  Geology and geophysics 

Supramolecular amplification of amyloid self-assembly by iodination OPEN
Arianna Bertolani, Lisa Pirrie, Loic Stefan, Nikolay Houbenov, Johannes S. Haataja, Luca Catalano, Giancarlo Terraneo, Gabriele Giancane, Ludovico Valli, Roberto Milani, Olli Ikkala, Giuseppe Resnati and Pierangelo Metrangolo
Amyloid assemblies lie at the heart of many physiological functions, as well as being the cause of numerous diseases. Here, the authors subtly modify wild-type pentapeptides with halides, and discover that the new halogen bonding interactions have a remarkable influence on their physical properties.
30 June 2015 | doi: 10.1038/ncomms8574
Chemical Sciences  Chemical biology  Materials science  Organic chemistry 

A porous metal-organic framework with ultrahigh acetylene uptake capacity under ambient conditions OPEN
Jiandong Pang, Feilong Jiang, Mingyan Wu, Caiping Liu, Kongzhao Su, Weigang Lu, Daqiang Yuan and Maochun Hong
The efficient storage of high-energy gaseous fuels is problematic due to the risk of explosion. Here, the authors design and employ a metal-organic framework composed of Cu(II) and an octacarboxylate ligand, which is able to store acetylene in high density but at atmospheric pressure.
30 June 2015 | doi: 10.1038/ncomms8575
Chemical Sciences  Inorganic chemistry  Materials science 

In vivo nanoparticle-mediated radiopharmaceutical-excited fluorescence molecular imaging OPEN
Zhenhua Hu, Yawei Qu, Kun Wang, Xiaojun Zhang, Jiali Zha, Tianming Song, Chengpeng Bao, Haixiao Liu, Zhongliang Wang, Jing Wang, Zhongyu Liu, Haifeng Liu and Jie Tian
Insufficient imaging sensitivity can make it challenging to assess early stage tumour lesions in vivo. Here, the authors present the radiopharmaceutical-excited fluorescence imaging technique that can detect tumour lesions less than 2 mm in size in living mice.
30 June 2015 | doi: 10.1038/ncomms8560
Biological Sciences  Medical research  Nanotechnology 

Experimental evidence of new tetragonal polymorphs of silicon formed through ultrafast laser-induced confined microexplosion OPEN
L. Rapp, B. Haberl, C.J. Pickard, J.E. Bradby, E.G. Gamaly, J.S. Williams and A.V. Rode
Ordinary materials can transform into exotic phases with new crystal structures at high pressure and temperature. Here, the authors demonstrate metastable phases of silicon, created by confined microexplosions initiated by ultrafast laser pulses, that are preserved for further utilisation.
29 June 2015 | doi: 10.1038/ncomms8555
Physical Sciences  Materials science 

Lost cold Antarctic deserts inferred from unusual sulfate formation and isotope signatures
Tao Sun, Richard A. Socki, David L. Bish, Ralph P. Harvey, Huiming Bao, Paul B. Niles, Ricardo Cavicchioli and Eric Tonui
Due to a paucity of terrestrial data, knowledge of the size of the East Antarctic ice sheet in the past is limited. Here, the authors present isotope data of sulfates from the Lewis Cliff Ice Tongue moraine, which suggest temporary existence of ice-free conditions in central Antarctica since the Miocene.
29 June 2015 | doi: 10.1038/ncomms8579
Earth Sciences  Biogeochemistry  Climate science  Geology and geophysics 

Atomic species identification at the (101) anatase surface by simultaneous scanning tunnelling and atomic force microscopy OPEN
Oleksandr Stetsovych, Milica Todorović, Tomoko K. Shimizu, César Moreno, James William Ryan, Carmen Pérez León, Keisuke Sagisaka, Emilio Palomares, Vladimír Matolín, Daisuke Fujita, Ruben Perez and Oscar Custance
Anatase is a pivotal material in devices for energy-harvesting applications and catalysis. Here, Stetsovych et al. demonstrate the potential of simultaneously combining atomic force microscopy and scanning tunnelling microscopy to identify the atomic species populating the (101) surface of anatase.
29 June 2015 | doi: 10.1038/ncomms8265
Physical Sciences  Condensed matter  Materials science 

Complex structural dynamics of nanocatalysts revealed in Operando conditions by correlated imaging and spectroscopy probes OPEN
Y. Li, D. Zakharov, S. Zhao, R. Tappero, U. Jung, A. Elsen, Ph. Baumann, R.G. Nuzzo, E.A. Stach and A.I. Frenkel
Studying a catalyst during reaction (operando conditions) can give significant insights into the changes a catalyst undergoes. Here, the authors use an operando approach to correlate X-ray spectroscopy and electron based imaging techniques to measure the dynamic changes in Pt nanoparticles during the catalytic hydrogenation of ethylene.
29 June 2015 | doi: 10.1038/ncomms8583
Chemical Sciences  Catalysis  Materials science  Nanotechnology 

Sprite streamer initiation from natural mesospheric structures
Ningyu Liu, Joseph R. Dwyer, Hans C. Stenbaek-Nielsen and Matthew G. McHarg
Sprites, electrical discharges in the upper atmosphere, are thought to be triggered by inhomogeneities. Here the authors present numerical models and propose that mesospheric structures created by atmospheric gravity waves can initiate sprite streamers, and also provide observations supporting this theory.
29 June 2015 | doi: 10.1038/ncomms8540
Earth Sciences  Atmospheric science 

Pliocene cooling enhanced by flow of low-salinity Bering Sea water to the Arctic Ocean OPEN
Keiji Horikawa, Ellen E. Martin, Chandranath Basak, Jonaotaro Onodera, Osamu Seki, Tatsuhiko Sakamoto, Minoru Ikehara, Saburo Sakai and Kimitaka Kawamura
Late Pliocene cooling led to the glaciation of the Northern Hemisphere, yet its trigger remains unclear. Here, the authors present neodymium and lead isotope records from the Bering Sea, and propose that the introduction of low-salinity water into the Arctic Ocean preconditioned Pliocene cooling.
29 June 2015 | doi: 10.1038/ncomms8587
Earth Sciences  Climate science  Oceanography 

Decarbonylative organoboron cross-coupling of esters by nickel catalysis OPEN
Kei Muto, Junichiro Yamaguchi, Djamaladdin G. Musaev and Kenichiro Itami
The Suzuki-Miyaura cross-coupling is a mainstay of organic synthesis, allowing carbon-carbon bond formation between a variety of coupling partners. Here, the authors report a decarbonylative process, whereby alkyl or aryl esters can be coupled with organoboron compounds using nickel catalysts.
29 June 2015 | doi: 10.1038/ncomms8508
Chemical Sciences  Catalysis  Organic chemistry 

Cidea improves the metabolic profile through expansion of adipose tissue
Gustavo Abreu-Vieira, Alexander W. Fischer, Charlotte Mattsson, Jasper M.A. de Jong, Irina G. Shabalina, Mikael Rydén, Jurga Laurencikiene, Peter Arner, Barbara Cannon, Jan Nedergaard and Natasa Petrovic
Unlike rodents, humans produce the protein Cidea in white adipose tissue, where it associates with lipid droplets. Here the authors generate mice that express human Cidea in fat tissues to show Cidea exerts beneficial metabolic effects by regulating the expansion of visceral fat in response to a high-fat diet.
29 June 2015 | doi: 10.1038/ncomms8433
Biological Sciences  Medical research 

Extreme ultraviolet imaging of three-dimensional magnetic reconnection in a solar eruption OPEN
J. Q. Sun, X. Cheng, M. D. Ding, Y. Guo, E. R. Priest, C. E. Parnell, S. J. Edwards, J. Zhang, P. F. Chen and C. Fang
Magnetic reconnection is a fundamental energy release process taking place in various astrophysical environments, but it is difficult to observe it directly. Here, the authors provide evidence of three-dimensional magnetic reconnection in a solar eruption using combined perspectives of two spacecraft.
26 June 2015 | doi: 10.1038/ncomms8598
Physical Sciences  Astronomy 

Bipyramid-templated synthesis of monodisperse anisotropic gold nanocrystals OPEN
Jung-Hoon Lee, Kyle J. Gibson, Gang Chen and Yossi Weizmann
Tuning the morphology of nanoparticles can alter their optical properties but often at the cost of monodispersity. Here, the authors report the synthesis of monodisperse anisotropic gold nanoparticles with various tip geometries as well as highly tunable size augmentations from purified gold bipyramids.
26 June 2015 | doi: 10.1038/ncomms8571
Chemical Sciences  Inorganic chemistry  Materials science  Nanotechnology 

Sustainability and dynamics of outcrop-to-outcrop hydrothermal circulation OPEN
Dustin M. Winslow and Andrew T. Fisher
Much hydrothermal circulation occurs away from the mid-ocean ridges and out on ridge flanks, affecting lithospheric heat deficit, solute fluxes, and influencing the biosphere. Here, the authors use 3D simulations to look at what controls the circulation and flow rate between and through seamounts.
26 June 2015 | doi: 10.1038/ncomms8567
Earth Sciences  Geology and geophysics 

Adiabatic elimination-based coupling control in densely packed subwavelength waveguides OPEN
Michael Mrejen, Haim Suchowski, Taiki Hatakeyama, Chihhui Wu, Liang Feng, Kevin O’Brien, Yuan Wang and Xiang Zhang
Optical communications and quantum operations require active coupling control in closely packed integrated photonic circuits. Here, Mrejen et al. exploit adiabatic elimination to demonstrate active coupling control between two closely packed waveguides by tuning the mode index of an in-between decoupled waveguide.
26 June 2015 | doi: 10.1038/ncomms8565
Physical Sciences  Applied physics  Atomic and molecular physics  Optical physics 

Specificity and catalysis hardwired at the RNA–protein interface in a translational proofreading enzyme OPEN
Sadeem Ahmad, Sowndarya Muthukumar, Santosh Kumar Kuncha, Satya Brata Routh, Antony S.K. Yerabham, Tanweer Hussain, Venu Kamarthapu, Shobha P Kruparani and Rajan Sankaranarayanan
The editing domain of aminoacyl-tRNA synthetases is responsible for removing non-cognate amino acids from mischarged tRNAs. Here the authors show that the D-aminoacyl-tRNA deacylase fold of archaeal ThrRS does not rely on protein side chains for substrate specificity and catalysis.
26 June 2015 | doi: 10.1038/ncomms8552
Biological Sciences  Biochemistry  Biophysics 

Kinetics and fracture resistance of lithiated silicon nanostructure pairs controlled by their mechanical interaction OPEN
Seok Woo Lee, Hyun-Wook Lee, Ill Ryu, William D. Nix, Huajian Gao and Yi Cui
It is imperative to understand how individual Si nanostructures interact in battery operations. Here, the authors design well-defined crystalline Si nanopillars and show how mechanical interactions of neighbouring Si structures affect their reaction kinetics and fracture resistance during electrochemical lithiation.
26 June 2015 | doi: 10.1038/ncomms8533
Chemical Sciences  Materials science  Physical chemistry 

Modulation of the molecular spintronic properties of adsorbed copper corroles OPEN
Fan Wu, Jie Liu, Puneet Mishra, Tadahiro Komeda, John Mack, Yi Chang, Nagao Kobayashi and Zhen Shen
Modulation of the spin states of molecules adsorbed on metal surfaces facilitates potential spintronic applications. Here, the authors demonstrate the tuning of the electronic interaction between a gold surface and the ligand of a corrole complex, tuning its spin state through fused-ring-expansion.
26 June 2015 | doi: 10.1038/ncomms8547
Physical Sciences  Applied physics  Atomic and molecular physics  Condensed matter 

Structure and gating of the nuclear pore complex OPEN
Matthias Eibauer, Mauro Pellanda, Yagmur Turgay, Anna Dubrovsky, Annik Wild and Ohad Medalia
Nuclear pore complexes (NPCs) are large macromolecular assemblies that mediate the exchange of molecules between the nucleus and cytoplasm. Here the authors present a ∼20 Å cryo-EM structure of the X. laevis NPC in different states of transport to propose a model for the architecture of the NPC’s molecular gate within its central channel.
26 June 2015 | doi: 10.1038/ncomms8532
Biological Sciences  Biophysics  Cell biology  Molecular biology 

Hyperbolic phonon-polaritons in boron nitride for near-field optical imaging and focusing OPEN
Peining Li, Martin Lewin, Andrey V. Kretinin, Joshua D. Caldwell, Kostya S. Novoselov, Takashi Taniguchi, Kenji Watanabe, Fabian Gaussmann and Thomas Taubner
Hyperbolic phonon polariton modes in natural hyperbolic materials could have uses in near-field optical imaging, guiding, and focusing applications. Here Li et al. demonstrate enlarged imaging and super-resolution focusing from a flat slab of hexagonal boron nitride enabled by hyperbolic phonon polariton modes.
26 June 2015 | doi: 10.1038/ncomms8507
Physical Sciences  Materials science  Nanotechnology  Optical physics 

Probing three-dimensional sodiation–desodiation equilibrium in sodium-ion batteries by in situ hard X-ray nanotomography OPEN
Jiajun Wang, Christopher Eng, Yu-chen Karen Chen-Wiegart and Jun Wang
In situ 3D visualization of sodium-ion battery processes is challenging due to the highly active sodium metal and the sluggish kinetics. Here, the authors present a X-ray tomography technique, which enables tracking the sodiation–desodiation process of a Sn anode in battery operation.
26 June 2015 | doi: 10.1038/ncomms8496
Chemical Sciences  Materials science  Nanotechnology 

Co-translational capturing of nascent ribosomal proteins by their dedicated chaperones OPEN
Patrick Pausch, Ujjwala Singh, Yasar Luqman Ahmed, Benjamin Pillet, Guillaume Murat, Florian Altegoer, Gunter Stier, Matthias Thoms, Ed Hurt, Irmgard Sinning, Gert Bange and Dieter Kressler
The synthesis of ribosomes requires the orderly assembly of many proteins and large RNA molecules, a process that involves several assembly factors. Here the authors show that dedicated chaperones capture the N termini of specific nascent ribosomal proteins to promote folding and assembly into maturing ribosomes.
26 June 2015 | doi: 10.1038/ncomms8494
Biological Sciences  Biochemistry  Biophysics 

Glycan complexity dictates microbial resource allocation in the large intestine OPEN
Artur Rogowski, Jonathon A. Briggs, Jennifer C. Mortimer, Theodora Tryfona, Nicolas Terrapon, Elisabeth C. Lowe, Arnaud Baslé, Carl Morland, Alison M. Day, Hongjun Zheng, Theresa E. Rogers, Paul Thompson, Alastair R. Hawkins, Madhav P. Yadav, Bernard Henrissat, Eric C. Martens, Paul Dupree, Harry J. Gilbert and David N. Bolam
The human gut microbiota helps us to degrade complex dietary carbohydrates such as xylan and, in turn, the carbohydrate breakdown products control the structure of the microbiota. Here the authors characterize the xylan-degrading apparatus of a key member of the gut microbiota, Bacteroides ovatus.
26 June 2015 | doi: 10.1038/ncomms8481
Biological Sciences  Biochemistry  Microbiology 

Cell migration and antigen capture are antagonistic processes coupled by myosin II in dendritic cells OPEN
Mélanie Chabaud, Mélina L. Heuzé, Marine Bretou, Pablo Vargas, Paolo Maiuri, Paola Solanes, Mathieu Maurin, Emmanuel Terriac, Maël Le Berre, Danielle Lankar, Tristan Piolot, Robert S. Adelstein, Yingfan Zhang, Michael Sixt, Jordan Jacobelli, Olivier Bénichou, Raphaël Voituriez, Matthieu Piel and Ana-Maria Lennon-Duménil
Dendritic cells alternate between fast and slow migratory behaviours, however in the absence of a component of the antigen processing machinery, migration is uniform and fast. Chabaud et al. now show that slow migration results from the relocalisation of myosin II to the cell front where it promotes antigen capture.
25 June 2015 | doi: 10.1038/ncomms8526
Biological Sciences  Cell biology 

Lucilia cuprina genome unlocks parasitic fly biology to underpin future interventions OPEN
Clare A. Anstead, Pasi K. Korhonen, Neil D. Young, Ross S. Hall, Aaron R. Jex, Shwetha C. Murali, Daniel S.T. Hughes, Siu F. Lee, Trent Perry, Andreas J. Stroehlein, Brendan R.E. Ansell, Bert Breugelmans, Andreas Hofmann, Jiaxin Qu, Shannon Dugan, Sandra L. Lee, Hsu Chao, Huyen Dinh, Yi Han, Harsha V. Doddapaneni et al.
Lucilia cuprina is a parasitic blowfly of major economic importance worldwide that feeds on the tissues of animals such as sheep. Here, the authors sequence the genome of L. cuprina and provide insights into the fly’s molecular biology, interactions with the host animal and insecticide resistance.
25 June 2015 | doi: 10.1038/ncomms8344
Biological Sciences  Genetics 

Understanding nanocellulose chirality and structure–properties relationship at the single fibril level OPEN
Ivan Usov, Gustav Nyström, Jozef Adamcik, Stephan Handschin, Christina Schütz, Andreas Fall, Lennart Bergström and Raffaele Mezzenga
Cellulose is a material found in many different biological systems, but the fine structure at the single-molecule level is still being assessed. Here, the authors present high-resolution imaging of cellulose structures at the single particle level, finding evidence of chirality in bundles and fibrils.
25 June 2015 | doi: 10.1038/ncomms8564
Biological Sciences  Biochemistry  Materials science 

IL-1 receptor antagonist-deficient mice develop autoimmune arthritis due to intrinsic activation of IL-17-producing CCR2+Vγ6+γδ T cells
Aoi Akitsu, Harumichi Ishigame, Shigeru Kakuta, Soo-hyun Chung, Satoshi Ikeda, Kenji Shimizu, Sachiko Kubo, Yang Liu, Masayuki Umemura, Goro Matsuzaki, Yasunobu Yoshikai, Shinobu Saijo and Yoichiro Iwakura
Control of γδ T-cell activation remains incompletely understood. Here the authors show that during autoimmune arthritis development αβ CD4+ T cells recruit a subset of IL-17-producing γδ T cells to the joints, and that both components are essential to cause pathology in a mouse model of the disease.
25 June 2015 | doi: 10.1038/ncomms8464
Biological Sciences  Immunology 

Printable elastic conductors with a high conductivity for electronic textile applications OPEN
Naoji Matsuhisa, Martin Kaltenbrunner, Tomoyuki Yokota, Hiroaki Jinno, Kazunori Kuribara, Tsuyoshi Sekitani and Takao Someya
Printable electronics is highly desirable for high throughput device manufacture. Here, Matsuhisa et al. report an electric ink, made of a self-assembled network of sliver flakes on the surface of a fluorine rubber matrix, which exhibits high conductivity and mechanical durability to achieve this goal.
25 June 2015 | doi: 10.1038/ncomms8461
Physical Sciences  Nanotechnology 

A random forest approach to capture genetic effects in the presence of population structure
Johannes Stephan, Oliver Stegle and Andreas Beyer
The discovery and mapping of causal variants in genome-wide association studies requires taking into consideration a range of confounding factors that can impact the results of the analysis. Here Stephan et al. propose a mixed random forest that captures nonlinear associations while accounting for population structure simultaneously.
25 June 2015 | doi: 10.1038/ncomms8432
Biological Sciences  Genetics 

Piezoelectric effect in chemical vapour deposition-grown atomic-monolayer triangular molybdenum disulfide piezotronics OPEN
Junjie Qi, Yann-Wen Lan, Adam Z. Stieg, Jyun-Hong Chen, Yuan-Liang Zhong, Lain-Jong Li, Chii-Dong Chen, Yue Zhang and Kang L. Wang
Two-dimensional transition-metal-dichalcogenide materials should have strong piezoelectric properties, making them useful for nanosensors and piezotronics. Here, the authors experimentally demonstrate the piezoelectric effect in monolayer molybdenum disulfide and show how this can modulate conductivity.
25 June 2015 | doi: 10.1038/ncomms8430
Physical Sciences  Condensed matter  Materials science 

Two-dimensional isobutyl acetate production pathways to improve carbon yield OPEN
Yohei Tashiro, Shuchi H. Desai and Shota Atsumi
Achieving high carbon yields is crucial for biotechnological production of metabolites in engineered microorganisms. Here, Tashiro et al. generate E. coli strains that produce acetyl-CoA and a derived metabolite (isobutyl acetate) in the absence of pyruvate decarboxylation, leading to increased carbon yields.
25 June 2015 | doi: 10.1038/ncomms8488
Biological Sciences  Biochemistry  Biotechnology  Microbiology 

A plastic relationship between vinculin-mediated tension and adhesion complex area defines adhesion size and lifetime OPEN
Pablo Hernández-Varas, Ulrich Berge, John G. Lock and Staffan Strömblad
Cell-matrix adhesions may increase or decrease in size in response to tension; however, the factors determining which of these responses predominates remain unclear. Hernández-Varas et al. quantify the plastic relationship between adhesion size and tension and use modelling to explain this behaviour.
25 June 2015 | doi: 10.1038/ncomms8524
Biological Sciences  Biophysics  Cell biology 

IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection OPEN
Stanley Adoro, Juan R. Cubillos-Ruiz, Xi Chen, Maud Deruaz, Vladimir D. Vrbanac, Minkyung Song, Suna Park, Thomas T. Murooka, Timothy E. Dudek, Andrew D. Luster, Andrew M. Tager, Hendrik Streeck, Brittany Bowman, Bruce D. Walker, Douglas S. Kwon, Vanja Lazarevic and Laurie H. Glimcher
HIV-infected patients who maintain undetectable virus levels possess elevated plasma concentrations of IL-21. Here, Adoro et al. show that IL-21 inhibits early viral infection in humanized mice and suppresses HIV-1 replication in vitro by upregulating a microRNA via the regulatory protein STAT3.
25 June 2015 | doi: 10.1038/ncomms8562
Biological Sciences  Immunology  Microbiology  Virology 

Lead iodide perovskite light-emitting field-effect transistor OPEN
Xin Yu Chin, Daniele Cortecchia, Jun Yin, Annalisa Bruno and Cesare Soci
Hybrid organic–inorganic perovskites have shown great potential for use in optoelectronic applications. Here, the authors create solution-processed lead iodide perovskite light-emitting field-effect transistors and demonstrate both ambipolar behaviour and gate-assisted electroluminescence.
25 June 2015 | doi: 10.1038/ncomms8383
Physical Sciences  Applied physics  Materials science  Optical physics 

Nanoscale memristive radiofrequency switches
Shuang Pi, Mohammad Ghadiri-Sadrabadi, Joseph C. Bardin and Qiangfei Xia
Radiofrequency switches based on micro-electromechanical systems or phase-change materials are large and require high voltages. Here, the authors demonstrate a nanoscale radiofrequency switch based on a memristive device with actuation voltages as low as 0.4 V and a typical cutoff frequency of 35 THz.
25 June 2015 | doi: 10.1038/ncomms8519
Physical Sciences  Applied physics 

Caenorhabditis elegans is a useful model for anthelmintic discovery OPEN
Andrew R. Burns, Genna M. Luciani, Gabriel Musso, Rachel Bagg, May Yeo, Yuqian Zhang, Luckshika Rajendran, John Glavin, Robert Hunter, Elizabeth Redman, Susan Stasiuk, Michael Schertzberg, G. Angus McQuibban, Conor R. Caffrey, Sean R. Cutler, Mike Tyers, Guri Giaever, Corey Nislow, Andy G. Fraser, Calum A. MacRae et al.
Screening for new anthelmintic compounds that are active against parasitic nematodes is costly and labour intensive. Here, the authors use the non-parasitic nematode Caenorhabditis elegans to identify 30 anthelmintic lead compounds in an effective and cost-efficient manner.
25 June 2015 | doi: 10.1038/ncomms8485
Biological Sciences  Chemical biology  Genetics  Medicinal chemistry 

Nanoscale control of phonon excitations in graphene OPEN
Hyo Won Kim, Wonhee Ko, JiYeon Ku, Insu Jeon, Donggyu Kim, Hyeokshin Kwon, Youngtek Oh, Seunghwa Ryu, Young Kuk, Sung Woo Hwang and Hwansoo Suh
A fundamental understanding of electron–phonon interactions in graphene is crucial to developing graphene-based electronic and photonic devices. Here, the authors control the properties of phonons in graphene by tuning the interaction strength between graphene and an underlying platinum substrate.
25 June 2015 | doi: 10.1038/ncomms8528
Physical Sciences  Condensed matter  Nanotechnology 

Single-site trinuclear copper oxygen clusters in mordenite for selective conversion of methane to methanol OPEN
Sebastian Grundner, Monica A.C. Markovits, Guanna Li, Moniek Tromp, Evgeny A. Pidko, Emiel J.M. Hensen, Andreas Jentys, Maricruz Sanchez-Sanchez and Johannes A. Lercher
Copper-exchanged zeolites with mordenite structure can mimic the active sites in particulate methane monooxygenase. Here, the authors show that mordenite micropores can stabilize trinuclear copper-oxo clusters that exhibit a high reactivity towards activation of carbon–hydrogen bonds in methane.
25 June 2015 | doi: 10.1038/ncomms8546
Chemical Sciences  Catalysis  Inorganic chemistry  Physical chemistry 

Superstatistical analysis and modelling of heterogeneous random walks OPEN
Claus Metzner, Christoph Mark, Julian Steinwachs, Lena Lautscham, Franz Stadler and Ben Fabry
Conventional methods to quantify the migratory behaviour of cells assume that underlying parameters are constant. Mark et al. apply a superstatistical approach to extract time-dependent parameters of motile cells, and demonstrate an enhanced ability to distinguish between different migration strategies.
25 June 2015 | doi: 10.1038/ncomms8516
Biological Sciences  Biophysics  Cell biology 

Silicon carbide-free graphene growth on silicon for lithium-ion battery with high volumetric energy density OPEN
In Hyuk Son, Jong Hwan Park, Soonchul Kwon, Seongyong Park, Mark H. Rümmeli, Alicja Bachmatiuk, Hyun Jae Song, Junhwan Ku, Jang Wook Choi, Jae-man Choi, Seok-Gwang Doo and Hyuk Chang
The volume expansion of silicon is a big problem in lithium-ion batteries with silicon anodes. Here, the authors report direct graphene growth on silicon nanoparticles, which effectively mitigates the problem, leading to excellent electrochemical performance.
25 June 2015 | doi: 10.1038/ncomms8393
Chemical Sciences  Materials science 

Associative memory realized by a reconfigurable memristive Hopfield neural network
S.G. Hu, Y. Liu, Z Liu, T.P. Chen, J.J. Wang, Q. Yu, L.J. Deng, Y. Yin and Sumio Hosaka
Memristors are passive electrical components that can act like simple memories. Here, the authors use an array of hafnium oxide memristors to create a type of artificial neural network, known as a Hopfield network, that is capable of retrieving data from partial information
25 June 2015 | doi: 10.1038/ncomms8522
Physical Sciences  Applied physics 

Force-induced chemical reactions on the metal centre in a single metalloprotein molecule OPEN
Peng Zheng, Guilherme M. Arantes, Martin J. Field and Hongbin Li
The investigation of the chemical reactivity of metal centres in metalloproteins in aqueous solution is challenging. Here, the authors demonstrate the use of single molecule force spectroscopy to study the chemical reactivity of the iron-sulfur centre in rubredoxin in aqueous solution.
25 June 2015 | doi: 10.1038/ncomms8569
Biological Sciences  Biochemistry  Biophysics  Nanotechnology 

Adaptive rheology and ordering of cell cytoskeleton govern matrix rigidity sensing
Mukund Gupta, Bibhu Ranjan Sarangi, Joran Deschamps, Yasaman Nematbakhsh, Andrew Callan-Jones, Felix Margadant, René-Marc Mège, Chwee Teck Lim, Raphaël Voituriez and Benoît Ladoux
Adherent cells actively probe the rigidity of their substrates. Gupta et al. show that actin cytoskeleton rheology transitions from fluid to solid with increased substrate stiffness along with an isotropic to nematic ordering, implicating the remodelling of the whole actin network in rigidity sensing.
25 June 2015 | doi: 10.1038/ncomms8525
Biological Sciences  Biophysics  Cell biology 

Large Seebeck effect by charge-mobility engineering OPEN
Peijie Sun, Beipei Wei, Jiahao Zhang, Jan M. Tomczak, A.M. Strydom, M. Søndergaard, Bo B. Iversen and Frank Steglich
The Seebeck effect causes an electrical potential across a temperature gradient in a material, and is therefore useful for generating useful current from waste heat. Here, the authors show that the Seebeck effect can arise due to charge-carrier relaxation in addition to the conventional mechanism.
25 June 2015 | doi: 10.1038/ncomms8475
Physical Sciences  Materials science 

Strong piezoelectricity in single-layer graphene deposited on SiO2 grating substrates OPEN
Gonçalo da Cunha Rodrigues, Pavel Zelenovskiy, Konstantin Romanyuk, Sergey Luchkin, Yakov Kopelevich and Andrei Kholkin
Pristine graphene is not piezoelectric, but adsorbing dopant atoms can induce a piezoresponse by breaking the material’s inversion symmetry. Here the authors demonstrate strong out-of-plane piezoelectricity in graphene on a silica substrate, providing a system for two-dimensional sensing and actuation.
25 June 2015 | doi: 10.1038/ncomms8572
Physical Sciences  Materials science 

The sorting protein PACS-2 promotes ErbB signalling by regulating recycling of the metalloproteinase ADAM17
Sarah Louise Dombernowsky, Jacob Samsøe-Petersen, Camilla Hansson Petersen, Rachael Instrell, Anne-Mette Bornhardt Hedegaard, Laurel Thomas, Katelyn Mae Atkins, Sylvain Auclair, Reidar Albrechtsen, Kasper Johansen Mygind, Camilla Fröhlich, Michael Howell, Peter Parker, Gary Thomas and Marie Kveiborg
ErbB signalling is stimulated by the release of its ligands from the cell surface through metalloproteinase-dependent cleavage. Dombernowsky et al. show that this process is controlled by the sorting protein PACS-2, which enhances ErbB ligand release by regulating trafficking of the metalloprotease ADAM17.
25 June 2015 | doi: 10.1038/ncomms8518
Biological Sciences  Cell biology 

Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints
M. E. Mikucki, D. T. Fisher, J. Matsuzaki, J. J. Skitzki, N. B. Gaulin, J. B. Muhitch, A. W. Ku, J. G. Frelinger, K. Odunsi, T. F. Gajewski, A. D. Luster and S. S. Evans
Tumours secrete many lymphocyte-attracting chemokines. Here the authors show that despite the abundance of their ligands, CCR2 and CCR5 do not mediate trafficking of effector CD8 T cells into the tumour, whereas CXCR3 is essential for this process and for T-cell-based elimination of melanoma in mice.
25 June 2015 | doi: 10.1038/ncomms8458
Biological Sciences  Cancer  Immunology 

Design and discovery of a novel half-Heusler transparent hole conductor made of all-metallic heavy elements
Feng Yan, Xiuwen Zhang, Yonggang G. Yu, Liping Yu, Arpun Nagaraja, Thomas O. Mason and Alex Zunger
Materials that are both electrically conducting and transparent to light are vital for optoelectronic devices, but are rare. Here, the authors perform a quantum mechanical search for such materials and identify the compound TaIrGe as an unexpected possibility, which they then synthesize.
24 June 2015 | doi: 10.1038/ncomms8308
Physical Sciences  Materials science 

A genome-wide association study identifies multiple loci for variation in human ear morphology OPEN
Kaustubh Adhikari, Guillermo Reales, Andrew J. P. Smith, Esra Konka, Jutta Palmen, Mirsha Quinto-Sanchez, Victor Acuña-Alonzo, Claudia Jaramillo, William Arias, Macarena Fuentes, María Pizarro, Rodrigo Barquera Lozano, Gastón Macín Pérez, Jorge Gómez-Valdés, Hugo Villamil-Ramírez, Tábita Hunemeier, Virginia Ramallo, Caio C. Silva de Cerqueira, Malena Hurtado, Valeria Villegas et al.
The shape of the pinna varies widely in the general human population but the genetic basis of this variation is unknown. Here Adhikari et al. conduct a genome-wide association study in Latin Americans and discover seven gene regions influencing pinna morphology, including EDAR and TBX15.
24 June 2015 | doi: 10.1038/ncomms8500
Biological Sciences  Genetics 

Exosomes released by keratinocytes modulate melanocyte pigmentation OPEN
Alessandra Lo Cicero, Cédric Delevoye, Floriane Gilles-Marsens, Damarys Loew, Florent Dingli, Christelle Guéré, Nathalie André, Katell Vié, Guillaume van Niel and Graça Raposo
The activity of melanocytes determines skin pigmentation, and is regulated by a tight dialogue with keratinocytes. Here, the authors show that exosomes released by keratinocytes have a direct effect on melanocyte function, and exosome content is dependent on skin phototype and is modulated by ultraviolet B radiation.
24 June 2015 | doi: 10.1038/ncomms8506
Biological Sciences  Cell biology 

The immunomodulating V and W proteins of Nipah virus determine disease course OPEN
Benjamin A. Satterfield, Robert W. Cross, Karla A. Fenton, Krystle N. Agans, Christopher F. Basler, Thomas W. Geisbert and Chad E. Mire
Nipah virus (NiV) can be transmitted from bats and other animals to humans, causing severe encephalitis and respiratory disease. Here, Satterfield et al. show that the W protein of NiV modulates the host immune response and determines disease course in a ferret model of infection.
24 June 2015 | doi: 10.1038/ncomms8483
Biological Sciences  Immunology  Microbiology  Virology 

Ultralow noise miniature external cavity semiconductor laser OPEN
W. Liang, V. S. Ilchenko, D. Eliyahu, A. A. Savchenkov, A. B. Matsko, D. Seidel and L. Maleki
Optical metrology applications require lasers with high spectral purity but on-chip devices with sub-100 Hz linewidth are yet to be realized. Here, Liang et al. present a heterogeneously integrated, chip-scale semiconductor laser with 30 Hz integral linewidth and sub-Hz instantaneous linewidth.
24 June 2015 | doi: 10.1038/ncomms8371
Physical Sciences  Applied physics  Optical physics 

Imaging an aligned polyatomic molecule with laser-induced electron diffraction OPEN
Michael G. Pullen, Benjamin Wolter, Anh-Thu Le, Matthias Baudisch, Michaël Hemmer, Arne Senftleben, Claus Dieter Schröter, Joachim Ullrich, Robert Moshammer, C. D. Lin and Jens Biegert
Laser-induced electron diffraction can provide structural information on gas-phase molecules with high spatial and temporal resolution. Going beyond previous diatomic cases, Pullen et al. apply this approach to acetylene and show that it can be used to measure bond lengths for polyatomic molecules.
24 June 2015 | doi: 10.1038/ncomms8262
Physical Sciences  Atomic and molecular physics  Optical physics 

Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children OPEN
Heng Xu, Hui Zhang, Wenjian Yang, Rachita Yadav, Alanna C. Morrison, Maoxiang Qian, Meenakshi Devidas, Yu Liu, Virginia Perez-Andreu, Xujie Zhao, Julie M. Gastier-Foster, Philip J. Lupo, Geoff Neale, Elizabeth Raetz, Eric Larsen, W. Paul Bowman, William L. Carroll, Naomi Winick, Richard Williams, Torben Hansen et al.
Genome-wide association studies indicate a strong genetic susceptibility to acute lymphoblastic leukaemia in children, though the effect on protein-coding genes is not fully understood. Here Xu and Zhang et al. identify a missense variant in CDKN2A which reduces tumour suppression.
24 June 2015 | doi: 10.1038/ncomms8553
Biological Sciences  Cancer  Genetics 

Digital microfluidic immunocytochemistry in single cells OPEN
Alphonsus H. C. Ng, M. Dean Chamberlain, Haozhong Situ, Victor Lee and Aaron R. Wheeler
The ability to measure signalling responses in single cells following short pulses of stimulus would shed insight into temporal thresholds for cell activation. Here the authors introduce a microfluidic platform that allows downstream phosphorylation cascades to be observed following as little as one second of stimulus exposure.
24 June 2015 | doi: 10.1038/ncomms8513
Biological Sciences  Biotechnology  Cell biology 

Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3 OPEN
Seokwon Kang, Teresa Fernandes-Alnemri, Corey Rogers, Lindsey Mayes, Ying Wang, Christopher Dillon, Linda Roback, William Kaiser, Andrew Oberst, Junji Sagara, Katherine A. Fitzgerald, Douglas R. Green, Jianke Zhang, Edward S. Mocarski and Emad S. Alnemri
Inflammasome activation requires a complex and incompletely understood network of signalling events. Here the authors characterize step-by-step contributions of TLR3, caspase-8, RIPK3 and MLKL to the activation of NLRP3 inflammasome in response to double-stranded RNA.
24 June 2015 | doi: 10.1038/ncomms8515
Biological Sciences  Immunology  Molecular biology 

Resonant tunnelling in a quantum oxide superlattice
Woo Seok Choi, Sang A. Lee, Jeong Ho You, Suyoun Lee and Ho Nyung Lee
Quantum mechanical resonant tunnelling is believed to be only feasible in semiconductor-based heterostructures due to high crystalline quality required, which restricts the number of viable materials. Here, the authors demonstrate resonant tunnelling in a deliberately designed complex-oxide superlattice.
24 June 2015 | doi: 10.1038/ncomms8424
Physical Sciences  Applied physics  Materials science 

Temporal tweezing of light through the trapping and manipulation of temporal cavity solitons
Jae K. Jang, Miro Erkintalo, Stéphane Coen and Stuart G. Murdoch
Optical tweezing typically refers to the trapping and manipulation of particles using lasers. Here, Jang et al. demonstrate analogous manipulation of ultrashort cavity soliton-pulses in the time domain, trapped by the phase modulation of a continuous wave laser beam, and moved by modifying the phase profile.
24 June 2015 | doi: 10.1038/ncomms8370
Physical Sciences  Applied physics  Optical physics 

Grb2 monomer–dimer equilibrium determines normal versus oncogenic function OPEN
Zamal Ahmed, Zahra Timsah, Kin M. Suen, Nathan P. Cook, Gilbert R. Lee, Chi-Chuan Lin, Mihai Gagea, Angel A. Marti and John E. Ladbury
Grb2 is an adaptor protein that can exist as a dimer that dissociates on phosphorylation of Y160. Here, the authors show that only the monomeric protein is capable of activating mitogen-activated protein kinase signal transduction and hence control oncogenic outcome.
24 June 2015 | doi: 10.1038/ncomms8354
Biological Sciences  Cancer  Cell biology 

Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence OPEN
Maja Sedic, Adam Skibinski, Nelson Brown, Mercedes Gallardo, Peter Mulligan, Paula Martinez, Patricia J. Keller, Eugene Glover, Andrea L. Richardson, Janet Cowan, Amanda E. Toland, Krithika Ravichandran, Harold Riethman, Stephen P. Naber, Anders M. Näär, Maria A. Blasco, Philip W. Hinds and Charlotte Kuperwasser
BRCA1 functions in all cell types to help preserve genomic stability but oncogenesis is restricted to only a few tissues. Here Sedic et al. demonstrate a novel BRCA1 haploinsufficiency-induced senescence pathway in epithelial cells.
24 June 2015 | doi: 10.1038/ncomms8505
Biological Sciences  Cancer  Molecular biology 

Membranes with artificial free-volume for biofuel production OPEN
Nikos Petzetakis, Cara M. Doherty, Aaron W. Thornton, X. Chelsea Chen, Pepa Cotanda, Anita J. Hill and Nitash P. Balsara
The free-volume of a polymer is a key parameter in its ability to permit through transport of small molecules. Here, the authors develop a way of introducing different degrees of artificial free-volume to a polymer membrane, and thus tailor its penetrability for applications including biofuel purification.
24 June 2015 | doi: 10.1038/ncomms8529
Chemical Sciences  Materials science  Nanotechnology 

Enantiomer-specific analysis of multi-component mixtures by correlated electron imaging–ion mass spectrometry OPEN
Mohammad M Rafiee Fanood, N. Bhargava Ram, C. Stefan Lehmann, Ivan Powis and Maurice H. M. Janssen
Detecting enantiomers in dilute mixtures of volatile organic compounds is a challenge. Here, the authors demonstrate a method to identify enantiomers and enantiomeric excess in a multi-component mixture containing two chiral species using laser mass spectrometry and photoelectron circular dichroism.
24 June 2015 | doi: 10.1038/ncomms8511
Chemical Sciences  Analytical chemistry  Atomic and molecular physics  Physical chemistry 

Orbital reconstruction in nonpolar tetravalent transition-metal oxide layers OPEN
Nikolay A. Bogdanov, Vamshi M. Katukuri, Judit Romhányi, Viktor Yushankhai, Vladislav Kataev, Bernd Büchner, Jeroen van den Brink and Liviu Hozoi
The iridate compounds display interesting physical properties, including quasi-two-dimensional behaviour similar to cuprates. Bogdanov et al. explore the d-level structure of Sr2IrO4 using electron spin resonance measurements and detailed calculations and find it is inverted compared to its normal ordering
24 June 2015 | doi: 10.1038/ncomms8306
Physical Sciences  Condensed matter  Materials science 

Thermal transport in phononic crystals and the observation of coherent phonon scattering at room temperature
Seyedhamidreza Alaie, Drew F. Goettler, Mehmet Su, Zayd C. Leseman, Charles M. Reinke and Ihab El-Kady
Silicon-based semiconductors are attractive for thermoelectric devices, but their phonon-dominated thermal conductivity is preventing their use. Here, Alaie et al. observe coherent phonon boundary scattering in phononic crystals at room temperature by introducing large (=100 nm) air holes in the Si matrix.
24 June 2015 | doi: 10.1038/ncomms8228
Physical Sciences  Applied physics  Theoretical physics 

Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies
Laura K. Pritchard, Daniel I.R. Spencer, Louise Royle, Camille Bonomelli, Gemma E. Seabright, Anna-Janina Behrens, Daniel W. Kulp, Sergey Menis, Stefanie A. Krumm, D. Cameron Dunlop, Daniel J. Crispin, Thomas A. Bowden, Christopher N. Scanlan, Andrew B. Ward, William R. Schief, Katie J. Doores and Max Crispin
The glycan patch that covers the HIV-1 envelope protein gp120 can be targeted by broadly neutralizing antibodies. Here, Pritchard et al. show that structural changes in the glycans do not significantly hamper antibody recognition, supporting the glycan patch as a stable target for vaccine design.
24 June 2015 | doi: 10.1038/ncomms8479
Biological Sciences  Immunology  Molecular biology  Virology 

Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice OPEN
Nikhlesh K. Singh, Sivareddy Kotla, Elena Dyukova, James G. Traylor Jr., A. Wayne Orr, Jonathan Chernoff, Tony N. Marion and Gadiparthi N. Rao
Atherogenesis involves coordinated action of different cell types and factors. Here the authors show that the kinase Pak1 represents a key pro-atherogenic factor affecting the function of macrophages and vascular smooth muscle cells, including their production of proinflammatory cytokine IL-6 and chemokine MCP-1, and retention of cholesterol.
24 June 2015 | doi: 10.1038/ncomms8450
Biological Sciences  Cell biology  Medical research 

A scanning cavity microscope OPEN
Matthias Mader, Jakob Reichel, Theodor W. Hänsch and David Hunger
Fluorescence from nanoparticles enables high-resolution optical imaging, but this approach is limited to those structures that emit light. Here, the authors demonstrate a microscope that uses a cavity to enhance the measurement of the alternative optical properties of absorption and dispersion.
24 June 2015 | doi: 10.1038/ncomms8249

Linking megathrust earthquakes to brittle deformation in a fossil accretionary complex OPEN
Armin Dielforder, Hauke Vollstaedt, Torsten Vennemann, Alfons Berger and Marco Herwegh
Recent megathrust earthquakes have been documented to cause large-scale stress changes, although this has not been identified in a fossil system. Here, the authors present data that establish a link between the observations at active subduction zones and the structural record preserved in ancient mountain belts.
24 June 2015 | doi: 10.1038/ncomms8504
Earth Sciences 

Aging mechanisms in amorphous phase-change materials
Jean Yves Raty, Wei Zhang, Jennifer Luckas, Chao Chen, Riccardo Mazzarello, Christophe Bichara and Matthias Wuttig
Phase-change materials are a route to high-density data storage, but changes in their properties in time are a limiting factor. Here, the authors combine numerical simulations, photothermal deflection spectroscopy and impedance spectroscopy experiments to investigate the aging process in germanium telluride.
24 June 2015 | doi: 10.1038/ncomms8467
Physical Sciences  Materials science 

Ionic transport in hybrid lead iodide perovskite solar cells OPEN
Christopher Eames, Jarvist M. Frost, Piers R. F. Barnes, Brian C. O’Regan, Aron Walsh and M. Saiful Islam
Understanding the mechanism of ionic transport in organic–inorganic halide perovskites is crucial for the design of future solar cells. Here, Eames et al. undertake a combined experimental and computational study to elucidate the ion conducting species and help rationalize the unusual behaviour observed in these perovskite-based devices.
24 June 2015 | doi: 10.1038/ncomms8497
Physical Sciences  Applied physics  Materials science  Physical chemistry 
 
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Corrigendum: Evidence for photogenerated intermediate hole polarons in ZnO
Hikmet Sezen, Honghui Shang, Fabian Bebensee, Chengwu Yang, Maria Buchholz, Alexei Nefedov, Stefan Heissler, Christian Carbogno, Matthias Scheffler, Patrick Rinke and Christof Wöll
30 June 2015 | doi: 10.1038/ncomms8694

 
 
Corrigendum: Reduced IFNλ4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes
Ewa Terczyńska-Dyla, Stephanie Bibert, Francois H. T. Duong, Ilona Krol, Sanne Jørgensen, Emilie Collinet, Zoltán Kutalik, Vincent Aubert, Andreas Cerny, Laurent Kaiser, Raffaele Malinverni, Alessandra Mangia, Darius Moradpour, Beat Müllhaupt, Francesco Negro, Rosanna Santoro, David Semela, Nasser Semmo, Swiss Hepatitis C Cohort Study Group, Markus H. Heim et al.
29 June 2015 | doi: 10.1038/ncomms8280
Biological Sciences  Genetics  Immunology  Virology 
 
 

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