The EMBO Journal Table of Contents for 4 March 2015; Vol. 34, No. 5

4 March 2015 | Volume 34, Number 5 Submit Table of Contents Have you seen? Articles Volume 34, Number 5 Have you seen? Argonautes team up to silence transposable elements in Arabidopsis Two studies reveal that AGO6 cooperates with other argonaute proteins to silence transposable elements in plants. Charles J Underwood and Robert A Martienssen Published online 28.01.2015 Articles Specific but interdependent functions for Arabidopsis AGO4 and AGO6 in RNA‐directed DNA methylation AGO4 and AGO6 have distinct, but cooperative functions in RNA‐directed DNA methylation in Arabidopsis and show spatially segregated interactions with RNA polymerases II and V, respectively. Cheng‐Guo Duan, Huiming Zhang, Kai Tang, Xiaohong Zhu, Weiqiang Qian, Yueh‐Ju Hou, Bangshing Wang, Zhaobo Lang, Yang Zhao, Xingang Wang, Pengcheng Wang, Jianping Zhou, Gaimei Liang, Na Liu, Chunguo Wang, and Jian‐Kang Zhu Published online 19.12.2014 The mRNA decay factor PAT1 functions in a pathway including MAP kinase 4 and immune receptor SUMM2 The identification of mRNA decapping factor PAT1 as a new target for MAP kinase 4 offers insight on the emerging connection between RNA metabolism and immunity in plants. Milena Edna Roux, Magnus Wohlfahrt Rasmussen, Kristoffer Palma, Signe Lolle, Àngels Mateu Regué, Gerit Bethke, Jane Glazebrook, Weiping Zhang, Leslie Sieburth, Martin R Larsen, John Mundy, and Morten Petersen Published online 20.01.2015 miR‐290/371‐Mbd2‐Myc circuit regulates glycolytic metabolism to promote pluripotency New data reveal a miRNA‐Mbd2‐Myc network that directly controls metabolic enzymes to govern stem cell metabolism and pluripotency. Yang Cao, Wen‐Ting Guo, Shengya Tian, Xiaoping He, Xi‐Wen Wang, Xiaomeng Liu, Kai‐Li Gu, Xiaoyu Ma, De Huang, Lan Hu, Yongping Cai, Huafeng Zhang, Yangming Wang, and Ping Gao Published online 20.01.2015 Wnt activity and basal niche position sensitize intestinal stem and progenitor cells to DNA damage New genetic results suggest that DNA damage‐induced modulation of Wnt signaling determines radio‐sensitivity of intestinal stem‐ and progenitor cells. Si Tao, Duozhuang Tang, Yohei Morita, Tobias Sperka, Omid Omrani, André Lechel, Vadim Sakk, Johann Kraus, Hans A Kestler, Michael Kühl, and Karl Lenhard Rudolph Published online 21.01.2015 Progesterone and Wnt4 control mammary stem cells via myoepithelial crosstalk This paper ascribes a new role for Wnt4 in pre‐pubertal mammary gland development while revealing luminal cells to respond to Wnt activation. During regeneration, Wnt4 interacts with progesterone receptor signaling, correcting previous notions on RANKL signaling in this context. Renuga Devi Rajaram, Duje Buric, Marian Caikovski, Ayyakkannu Ayyanan, Jacques Rougemont, Jingdong Shan, Seppo J Vainio, Ozden Yalcin‐Ozuysal, and Cathrin Brisken Published online 20.01.2015 Nuclear matrix protein Matrin3 regulates alternative splicing and forms overlapping regulatory networks with PTB Matrin3 is a nuclear matrix protein that was recently linked to neurodegeneration. This study finds Matrin3 to be a splicing repressor that modulates hundreds of alternative splice events, offering possible insight on disease onset. Miguel B Coelho, Jan Attig, Nicolás Bellora, Julian König, Martina Hallegger, Melis Kayikci, Eduardo Eyras, Jernej Ule, and Christopher WJ Smith Published online 19.01.2015 Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase The aminophospholipid translocase ATP8A1 enriches phosphatidylserine at the cytosolic leaflet of recycling endosomes, recruiting fission protein EHD1. Phosphatidylserine translocation is required for cargo sorting and membrane fission, a process perturbed in CAMRQ disease‐associated ATP8A2 mutant cells. Shoken Lee, Yasunori Uchida, Jiao Wang, Tatsuyuki Matsudaira, Takatoshi Nakagawa, Takuma Kishimoto, Kojiro Mukai, Takehiko Inaba, Toshihide Kobayashi, Robert S Molday, Tomohiko Taguchi, and Hiroyuki Arai Published online 16.01.2015   Unsubscribe from or edit your subscription for this service. Or by mail: Customer Service * 425 Broadway St * Redwood City, CA 94063 * U.S.A. Copyright © 2015 by the European Molecular Biology Organisation.