TABLE OF CONTENTS |
March 2015 Volume 11, Issue 3 |
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| Research Highlights News and Views Perspective Brief Communications Articles Errata Corrigendum
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Featured contents published recently in Experimental & Molecular Medicine (EMM): EMM publishes the latest and most important advances in genetic, molecular and cellular studies of human physiology and diseases. | | | |
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Research Highlights | Top |
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Quorum sensing: mRNA tug of war | Non-natural amino acids: A synthetase swap | Protein aggregation: Curling damage | Protein design: We built this protein | RNA epigenetics: m6A partial differential | Lipid-protein interactions: Three sites in PTEN
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News and Views | Top |
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Perspective | Top |
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Collective antibiotic tolerance: mechanisms, dynamics and intervention pp182 - 188 Hannah R Meredith, Jaydeep K Srimani, Anna J Lee, Allison J Lopatkin and Lingchong You doi:10.1038/nchembio.1754
This Perspective describes the different modes by which bacteria belonging to a population can achieve resistance to antibiotic treatments that are otherwise lethal to individual cells and suggests that such mechanisms of collective antibiotic tolerance can be targeted for development of antimicrobials.
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Brief Communications | Top |
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Articles | Top |
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Creating small transcription activating RNAs pp214 - 220 James Chappell, Melissa K Takahashi and Julius B Lucks doi:10.1038/nchembio.1737
RNA has been used in a variety of synthetic biology circuits but never as a transcriptional activator. Two design strategies using synthetic and natural sequences now lead to RNA activators, enabling RNA-only logic gates.
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Local and macroscopic electrostatic interactions in single α-helices pp221 - 228 Emily G Baker, Gail J Bartlett, Matthew P Crump, Richard B Sessions, Noah Linden et al. doi:10.1038/nchembio.1739
A series of designed peptides call the sphere of influence of the helix macrodipole into question, showing that the favorable rotamers allowed by K→E hydrogen bonds beat out the entropically penalized but macrodipole-aligned E→K hydrogen bonds.
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Errata | Top |
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Erratum: Rick Morimoto p235 Catherine Goodman doi:10.1038/nchembio0315-235a
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Erratum: Covalent docking of large libraries for the discovery of chemical probes p235 Nir London, Rand M Miller, Shyam Krishnan, Kenji Uchida, John J Irwin et al. doi:10.1038/nchembio0315-235b
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Subcellular metal imaging identifies dynamic sites of Cu accumulation in Chlamydomonas p235 Anne Hong-Hermesdorf, Marcus Miethke, Sean D Gallaher, Janette Kropat, Sheel C Dodani et al. doi:10.1038/nchembio0315-235c
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Corrigendum | Top |
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Corrigendum: Hydrolysis of 2′3′-cGAMP by ENPP1 and design of nonhydrolyzable analogs p235 Lingyin Li, Qian Yin, Pia Kuss, Zoltan Maliga, Jose L Millan et al. doi:10.1038/nchembio0315-235d
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