The EMBO Journal - Table of Contents alert Volume 32 Issue 2

TABLE OF CONTENTS 23 January 2013 | Volume 32, Issue 2 Have you seen? Reviews Articles Also new AOP Sign up for e-alerts Recommend to your library Web feed Subscribe Advertisement EMBO - Transparency in Scientific Publishing The EMBO Journal has a fair and transparent process to rapidly publish your best science. Transparent - No confidential referee remarks - Published referee reports - Detailed decisions - Source Data published alongside figures Fair - Scooping protection - Pre-decision cross-referee commenting - Fixed bar for revisions - Fast process   Have you seen? Top Don’t get stuck in the pore Hydrogel-forming nucleoporins prevent passive diffusion of inert macromolecules through nuclear pore complexes, while allowing active transport of proteins and nucleic acids across the nuclear envelope. Wolfram Antonin The EMBO Journal (2013), 32, 173 - 175; 10.1038/emboj.2012.338 Abstract | Full text | PDF | Related article Published online: 14 December 2012 Subdivision of bone marrow microenvironments: purpose built homes for haematopoietic stem cells Innovative in vivo gene labelling allowed the characterization of a novel bone marrow architecture called haemospheres that functionally aids the expansion of haematopoietic precursor cells. Edwin D Hawkins and Cristina Lo Celso The EMBO Journal (2013), 32, 176 - 177; 10.1038/emboj.2012.337 Abstract | Full text | PDF | Related article Published online: 18 December 2012 Reviews Top Stem cell function during plant vascular development Helariutta and colleagues review recent advances in our understanding of plant stem cell organization and maintenance and its regulation by transcription factors and plant hormones. Shunsuke Miyashima, Jose Sebastian, Ji-Young Lee and Yka Helariutta The EMBO Journal (2013), 32, 178 - 193; 10.1038/emboj.2012.301 Abstract | Full text | PDF Published online: 20 November 2012 Subject Categories: Development | Plant Biology The cancer antigenome Ton Schumacher and colleagues review recent genomic advances that make it feasible to identify the repertoire of tumour-associated epitopes in order to establish effective immunotherapy. Bianca Heemskerk, Pia Kvistborg and Ton N M Schumacher The EMBO Journal (2013), 32, 194 - 203; 10.1038/emboj.2012.333 Abstract | Full text | PDF Published online: 21 December 2012 Subject Categories: Immunology | Molecular Biology of Disease Articles Top Systematic analysis of barrier-forming FG hydrogels from Xenopus nuclear pore complexes The phenylalanine-glycine (FG) domains of vertebrate nucleoporins assemble into hydrogels with different sieving characteristics for macromolecules. Nup98 forms the tightest filter, which is relieved by O-linked glycosylation. Aksana A Labokha, Sabine Gradmann, Steffen Frey, Bastian B Hülsmann, Henning Urlaub, Marc Baldus and Dirk Görlich The EMBO Journal (2013), 32, 204 - 218; 10.1038/emboj.2012.302 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 30 November 2012 Subject Categories: Membranes and Transport | Proteins Identification of a clonally expanding haematopoietic compartment in bone marrow This investigation into the structural architecture of the adult bone marrow identifies vessel-associated compartments that functionally serve haematopoietic proliferation and clonal expansion. Lin Wang, Rui Benedito, M Gabriele Bixel, Dagmar Zeuschner, Martin Stehling, Lars Sävendahl, Jody J Haigh, Hugo Snippert, Hans Clevers, Georg Breier, Friedemann Kiefer and Ralf H Adams The EMBO Journal (2013), 32, 219 - 230; 10.1038/emboj.2012.308 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 27 November 2012 Subject Categories: Cell and Tissue Architecture | Molecular Biology of Disease Foxm1 transcription factor is required for lung fibrosis and epithelial-to-mesenchymal transition This study establishes the in vivo relevance of FoxM1 in the context of radiation-induced fibrosis. FoxM1 ablation in the respiratory epithelium supports a regulatory role during EMT and pulmonary inflammation that could become of therapeutic relevance. David Balli, Vladimir Ustiyan, Yufang Zhang, I-Ching Wang, Alex J Masino, Xiaomeng Ren, Jeffrey A Whitsett, Vladimir V Kalinichenko and Tanya V Kalin The EMBO Journal (2013), 32, 231 - 244; 10.1038/emboj.2012.336 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 04 January 2013 Subject Categories: Signal Transduction | Chromatin and Transcription | Molecular Biology of Disease Drosophila ATP6AP2/VhaPRR functions both as a novel planar cell polarity core protein and a regulator of endosomal trafficking In addition to its role in vesicle acidification and sorting, the V-ATPase regulatory subunit ATP6AP2/VhaPRR is a new core component of the planar cell polarity (PCP) pathway in Drosophila. VhaPRR interacts with PCP protein Flamingo (Fmi) and regulates the asymmetric distribution of PCP components in wing epithelial cells. Tobias Hermle, Maria Clara Guida, Samuel Beck, Susanne Helmstädter and Matias Simons The EMBO Journal (2013), 32, 245 - 259; 10.1038/emboj.2012.323 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 04 January 2013 Subject Categories: Membranes and Transport | Development SCFTIR1/AFB-auxin signalling regulates PIN vacuolar trafficking and auxin fluxes during root gravitropism A gradient of the phytohormone Auxin regulates root gravitropism. Too low or high auxin promotes the vacuolar targeting and degradation of the auxin transporter PIN2 via the SCFTIR1/AFB pathway. Paweł Baster, Stéphanie Robert, Jürgen Kleine-Vehn, Steffen Vanneste, Urszula Kania, Wim Grunewald, Bert De Rybel, Tom Beeckman and Jiří Friml The EMBO Journal (2013), 32, 260 - 274; 10.1038/emboj.2012.310 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 04 December 2012 Subject Categories: Signal Transduction | Plant Biology Tbf1 and Vid22 promote resection and non-homologous end joining of DNA double-strand break ends The yeast Myb domain protein Tbf1, previously implicated in telomeric processes and transcriptional activation, promotes efficient DNA break repair by influencing nucleosome displacement at sites of damage. Diego Bonetti, Savani Anbalagan, Giovanna Lucchini, Michela Clerici and Maria Pia Longhese The EMBO Journal (2013), 32, 275 - 289; 10.1038/emboj.2012.327 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 07 December 2012 Subject Categories: Chromatin and Transcription | Genome Stability and Dynamics Initiation of DNA damage responses through XPG-related nucleases The newly identified, conserved nuclease Ast1 cooperates with Exo1 and Rad2/Fen1 in the processing of DNA double-strand breaks and subsequent checkpoint activation. Karen Kuntz and Matthew J O’Connell The EMBO Journal (2013), 32, 290 - 302; 10.1038/emboj.2012.322 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 04 December 2012 Subject Categories: Genome Stability and Dynamics Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C–Cdc20 complex Identification of a kinesin as novel APC/C ubiquitination substrate offers insight into molecular determinants of differential degradation timing during early mitosis. Garry G Sedgwick, Daniel G Hayward, Barbara Di Fiore, Mercedes Pardo, Lu Yu, Jonathon Pines and Jakob Nilsson The EMBO Journal (2013), 32, 303 - 314; 10.1038/emboj.2012.335 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 04 January 2013 Subject Categories: Proteins | Cell Cycle Advertisement Follow EMBO on Facebook for as-it-happens access to news, comments and articles and make it a place to share information with others interested in the field. www.facebook.com/EMBO.excellence.in.life.sciences   Please note that you need to be a subscriber or site-licence holder to enjoy full-text access to The EMBO Journal. In order to do so, please purchase a subscription. You have been sent this Table of Contents Alert because you have opted in to receive it. 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