| |  | | | | | Weekly Content Alert
|  | | 19 June 2012 | | | Featured image: | |  | | | Melcer et al. delineate mechanisms of chromatin plasticity in embryonic stem cells and differentiated neural precursors. |
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Advertisement | | Nature Reviews Molecular Cell Biology
FOCUS ON METABOLISM
Cells rapidly adapt to changes in nutrient availability and integrate this information about their metabolic state to drive cellular processes. Unprecedented insights are being gained into the molecular basis of how metabolic pathways interface with cell biological processes and how this can be disrupted in metabolic disorders.
Read the Focus online at:
http://www.nature.com/nrm/focus/metabolism |
| | | | | | Latest Articles | View all Articles | | | | | Dynamic Jahn–Teller effect in the parent insulating state of the molecular superconductor Cs3C60 | | | Gyöngyi Klupp, Péter Matus, Katalin Kamarás, Alexey Y. Ganin, Alec McLennan, Matthew J. Rosseinsky, Yasuhiro Takabayashi, Martin T. McDonald and Kosmas Prassides | | | Expanded alkali fullerides are molecular superconductors with a Mott parent insulating state. Klupp et al. use infrared spectroscopy to detect the molecular Jahn–Teller distortion of fulleride ions and establish its relevance to strongly correlated superconductivity. | | | 19 Jun | Nat Commun 3:912 doi:10.1038/ncomms1910 (2012) | | | Physical sciences Condensed matter | | | Materials science | | Abstract | Full Text | PDF (556 kB) |
Supplementary Information |
| SUMO1 modification of PTEN regulates tumorigenesis by controlling its association with the plasma membrane | | | Jian Huang, Jie Yan, Jian Zhang, Shiguo Zhu, Yanli Wang, Ting Shi, Changhong Zhu, Cheng Chen, Xin Liu, Jinke Cheng, Tomas Mustelin, Gen-Sheng Feng, Guoqiang Chen and Jianxiu Yu | | | PTEN is a tumour suppressor that inhibits activation of the phosphatidylinositol 3-kinase pathway. These authors show that PTEN is SUMOylated on two lysine residues and that this modification is required for binding to acidic phospholipids and blocking tumour formation in mice. | | | 19 Jun | Nat Commun 3:911 doi:10.1038/ncomms1919 (2012) | | | Biological sciences Cancer | | | Cell biology | | Abstract | Full Text | PDF (1,261 kB) |
Supplementary Information |
| Histone modifications and lamin A regulate chromatin protein dynamics in early embryonic stem cell differentiation | | | Shai Melcer, Hadas Hezroni, Eyal Rand, Malka Nissim-Rafinia, Arthur Skoultchi, Colin L. Stewart, Michael Bustin and Eran Meshorer | | | Chromatin in embryonic stem cells is present in an open state presumably to facilitate gene expression changes required for pluripotency and subsequent multilineage differentiation. This study describes roles for lamin A, histone acetylation and G9a-mediated histone H3 lysine 9 methylation in regulating chromatin plasticity in these cells. | | | 19 Jun | Nat Commun 3:910 doi:10.1038/ncomms1915 (2012) | | | Biological sciences Molecular biology | | | | Abstract | Full Text | PDF (4,516 kB) |
Supplementary Information |
| Neuronal influence on peripheral circadian oscillators in pupal Drosophila prothoracic glands OPEN | | | Eri Morioka, Akira Matsumoto and Masayuki Ikeda | | | In the fruit fly Drosophila, changes in expression of circadian clock genes are believed to control eclosion. Morioka and colleagues show that transcriptional oscillations of the clock gene, period, in prothoracic gland cells are amplified by photic inputs from the central nervous system. | | | 19 Jun | Nat Commun 3:909 doi:10.1038/ncomms1922 (2012) | | | Biological sciences Neuroscience | | Abstract | Full Text | PDF (1,608 kB) |
Supplementary Information |
| Lifetime blinking in nonblinking nanocrystal quantum dots OPEN | | | Christophe Galland, Yagnaseni Ghosh, Andrea Steinbrück, Jennifer A. Hollingsworth, Han Htoon and Victor I. Klimov | | | Nanocrystal quantum dots can exhibit photoluminescence blinking, where the intensity of the emitted light fluctuates due to random charging and discharging. Galland et al. study thick shell nanocrystals and find that the photoluminescence lifetime can also undergo blinking, without intensity changes. | | | 19 Jun | Nat Commun 3:908 doi:10.1038/ncomms1916 (2012) | | | Physical sciences Materials science | | | Nanotechnology | | | Optical physics | | Abstract | Full Text | PDF (527 kB) |
Supplementary Information |
| Visualizing specific protein glycoforms by transmembrane fluorescence resonance energy transfer | | | Yoshimi Haga, Kumiko Ishii, Kayo Hibino, Yasushi Sako, Yukishige Ito, Naoyuki Taniguchi and Tadashi Suzuki | | | A common post-translational modification is the attachment of sugars, but proteins with different sugar chains, known as glycoforms, are hard to distinguish. Here, the authors use transmembrane fluorescence resonance energy transfer to visualize specific glycoforms of the membrane protein GLUT4 in living cells. | | | 19 Jun | Nat Commun 3:907 doi:10.1038/ncomms1906 (2012) | | | Biological sciences Biochemistry | | | Chemical biology | | Abstract | Full Text | PDF (522 kB) |
Supplementary Information |
| Light–matter interaction in a microcavity-controlled graphene transistor OPEN | | | Michael Engel, Mathias Steiner, Antonio Lombardo, Andrea C. Ferrari, Hilbert v. Löhneysen, Phaedon Avouris and Ralph Krupke | | | Graphene's remarkable properties make it ideal for optoelectronic devices, and its two-dimensional nature enables its integration with photonic structures. By combining a graphene transistor with a planar microcavity, Engel et al. control the spectrum of the photocurrent and the light emitted by the device. | | | 19 Jun | Nat Commun 3:906 doi:10.1038/ncomms1911 (2012) | | | Physical sciences Applied physics | | | Optical physics | | Abstract | Full Text | PDF (647 kB) |
Supplementary Information |
| Transmembrane anion transport mediated by halogen-bond donors | | | Andreas Vargas Jentzsch, Daniel Emery, Jiri Mareda, Susanta K. Nayak, Pierangelo Metrangolo, Giuseppe Resnati, Naomi Sakai and Stefan Matile | | | The transport of anions across bilayer membranes is achieved by ion channel proteins, but some small molecules are also able to mediate transmembrane movement of anions. In this study, the halogen bonding of small perfluorinated molecules is shown to allow the transmembrane movement of anions. | | | 19 Jun | Nat Commun 3:905 doi:10.1038/ncomms1902 (2012) | | | Chemical sciences Chemical biology | | | | Abstract | Full Text | PDF (613 kB) |
Supplementary Information |
| Electric dipoles on magnetic monopoles in spin ice | | | D.I. Khomskii | | | Spin ice is a state of matter that occurs in certain rare earth magnets with a pyrochlore structure. Here it is shown theoretically that, in conjunction with the magnetic monopoles observed in previous experiments, spin ice can also host electric dipoles. | | | 19 Jun | Nat Commun 3:904 doi:10.1038/ncomms1904 (2012) | | | Physical sciences Condensed matter | | | Theoretical physics | | | Abstract | Full Text | PDF (324 kB) |
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Advertisement | | Nature Neuroscience
FOCUS ON SOCIAL NEUROSCIENCE
This Focus discusses how the brain implements social processes and behavior, and how these processes are in turn modified by the brain, to influence things ranging from physical and mental health to the punishment of deviation from social norms.
Read this Focus online:
www.nature.com/neuro/focus/socialneuroscience |
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