The EDGE: Nature contents: 9 December 2010

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---THIS WEEK'S HIGHLIGHTS:

--Biological Sciences
-Gene expression divergence recapitulates the developmental hourglass
model
Early embryologists observed that appearance of embryos in related
species appears to converge midway through development, diverging
thereafter. The reality of this 'developmental hourglass' has
remained in doubt but new experiments bring it firmly into the
genomics age.
[ http://links.ealert.nature.com/ctt?kn=85&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0 ]

--Biological Sciences
-Cap binding and immune evasion revealed by Lassa nucleoprotein
structure
The first crystal structure of Lassa fever virus nucleoprotein
reveals unexpected functions - including exonuclease activity capable
of cleaving short RNAs and suppressing virus-induced interferon
induction.
[ http://links.ealert.nature.com/ctt?kn=88&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0 ]

--Physical Sciences
-A lower limit of [Delta]z > 0.06 for the duration of the
reionization epoch
A new generation of radio telescopes is providing a window onto the
period in the early Universe when the gas between the galaxies was
reionized.
[ http://links.ealert.nature.com/ctt?kn=82&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0 ]

=========================== ADVERTISEMENT ===========================

RIKEN RESEARCH
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The latest in news and research from RIKEN, Japan's flagship research
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--Podcast & Video
-A taste of lab-grown meat, a fresh take on an old theory of how
embryos develop and what the Earth's outer core is made of.
[ http://links.ealert.nature.com/ctt?kn=120&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0 ]

======================== NEWS AND COMMENT ========================
Read daily news coverage http://links.ealert.nature.com/ctt?kn=104&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

EDITORIALS
** Singapore's salad days are over
Uncertainty has replaced confidence as economic reality bites science
in the city-state and scientists find that their research funds now
come with strings attached.
http://links.ealert.nature.com/ctt?kn=83&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Animal instinct
Germany must better explain the scientific use of animals to remain
a major biomedical force.
http://links.ealert.nature.com/ctt?kn=92&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Give up the ghosts
Funding agencies should make researchers reveal industry links.
http://links.ealert.nature.com/ctt?kn=93&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

WORLD VIEW
** Women scientists must speak out
Female researchers still battle sexism. The media gives them an
opportunity to be heard alongside male colleagues,
says Jennifer Rohn
http://links.ealert.nature.com/ctt?kn=121&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

SEVEN DAYS
** Seven days: 3-9 December 2010
The week in science
http://links.ealert.nature.com/ctt?kn=128&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

NEWS
** Islands champion tuna ban
Pacific nations to restrict fishing across a vast swathe of
international waters.
http://links.ealert.nature.com/ctt?kn=136&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Microbe gets toxic response
Researchers question the science behind last week's revelation of
arsenic-based life.
http://links.ealert.nature.com/ctt?kn=126&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Basel Declaration defends animal research
Dialogue with public is key to reducing opposition over the use of
lab animals.
http://links.ealert.nature.com/ctt?kn=127&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Trial draws fire
Nobel laureate to test link between autism and infection.
http://links.ealert.nature.com/ctt?kn=138&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** River chief resigns
Plan to save Australian river system runs aground.
http://links.ealert.nature.com/ctt?kn=125&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Self-plagiarism case prompts calls for agencies to
tighten rules
Technology is bringing down instances of duplication, despite
variability in oversight.
http://links.ealert.nature.com/ctt?kn=122&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Stem-cell progress
Replacing genes with drugs could allow safe reprogramming.
http://links.ealert.nature.com/ctt?kn=123&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

FEATURES
** Condensed matter: The supersolid's nemesis
John Reppy has come out of retirement to question the high-profile
discovery of a new kind of quantum matter.
http://links.ealert.nature.com/ctt?kn=119&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Food: A taste of things to come?
Researchers are sure that they can put lab-grown meat on the menu —
if they can just get cultured muscle cells to bulk up.
http://links.ealert.nature.com/ctt?kn=139&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

COMMENT
** Lessons from Bayh-Dole
Developing countries wanting to boost commercialization of their
academic research should learn from the mistakes of US patenting
legislation, says Bhaven N. Sampat.
http://links.ealert.nature.com/ctt?kn=66&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** More for the research dollar
Funders and universities should make the products of research more
available -- even if today's researchers pay a price, say Jeffrey L.
Furman, Fiona Murray and Scott Stern.
http://links.ealert.nature.com/ctt?kn=70&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

BOOKS AND ARTS
** Biography: The ABC of computing
An engaging biography of John Atanasoff reveals the obscure origins
of the computer, explains John Gilbey.
http://links.ealert.nature.com/ctt?kn=69&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=72&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Sculpture: Engineering art
Neil Dodgson admires the technical mastery of sculptor Anish Kapoor.
http://links.ealert.nature.com/ctt?kn=71&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Bibliometrics: Measure for measure
A useful guide to citation analysis shows that counting publications
is harder than it looks, finds Ton van Raan.
http://links.ealert.nature.com/ctt?kn=74&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Conservation: A magical process
Prince Charles's call to stay close to nature follows a rich
tradition of environmental thinking, says Philip Stott.
http://links.ealert.nature.com/ctt?kn=73&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

CORRESPONDENCE
** Ease public concern over oil pipeline
John B. Gates
http://links.ealert.nature.com/ctt?kn=113&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Sustainable cities: seeing past the trees
Rob MacKenzie, Tom Pugh and Chris Rogers
http://links.ealert.nature.com/ctt?kn=114&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Time to underpin Wikipedia wisdom
Alex Bateman and Darren W. Logan
http://links.ealert.nature.com/ctt?kn=90&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Guest authors: for contributors only
Mark J. van Raaij
http://links.ealert.nature.com/ctt?kn=103&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Guest authors: no place in any journal
Richard M. Glass
http://links.ealert.nature.com/ctt?kn=100&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

OBITUARY
** Michael Tinkham (1928-2010)
Physicist who helped to unravel the mysteries of superconductivity.
http://links.ealert.nature.com/ctt?kn=97&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

CORRECTIONS
** Correction
http://links.ealert.nature.com/ctt?kn=95&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Correction
http://links.ealert.nature.com/ctt?kn=111&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

=========================== ADVERTISEMENT ===========================
Nature Biotechnology
FOCUS ON EPIGENETICS

This Focus summarizes the progress that has been made in
characterizing the epigenetic basis of disease and developmental
pathways, and discusses the technologies that have made rapid
progress possible in recent years, showing how those insights can
be translated into practical applications.

Read the Focus online for FREE until April 15, 2011:
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=====================================================================

======================== BIOLOGICAL SCIENCES ========================
RESEARCH
** Cap binding and immune evasion revealed by Lassa nucleoprotein
structure
Xiaoxuan Qi, Shuiyun Lan, Wenjian Wang, Lisa McLay Schelde,
Haohao Dong et al.
Lassa virus, the causative agent of Lassa fever, causes thousands of
deaths ann...
http://links.ealert.nature.com/ctt?kn=88&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Structure of a bacterial ribonuclease P holoenzyme in complex
with tRNA
Nicholas J. Reiter, Amy Osterman, Alfredo Torres-Larios,
Kerren K. Swinger, Tao Pan et al.
Ribonuclease (RNase) P is the universal ribozyme responsible for
5[prime]-end...
http://links.ealert.nature.com/ctt?kn=108&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Quantitative reactivity profiling predicts functional cysteines
in proteomes
Eranthie Weerapana, Chu Wang, Gabriel M. Simon, Florian Richter,
Sagar Khare et al.
Cysteine is the most intrinsically nucleophilic amino acid in
proteins, where i...
http://links.ealert.nature.com/ctt?kn=106&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Gene expression divergence recapitulates the developmental
hourglass model
Alex T. Kalinka, Karolina M. Varga, Dave T. Gerrard,
Stephan Preibisch, David L. Corcoran et al.
The observation that animal morphology tends to be conserved during
the embryon...
http://links.ealert.nature.com/ctt?kn=85&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** A phylogenetically based transcriptome age index mirrors
ontogenetic divergence patterns
Tomislav Domazet-Loso and Diethard Tautz
Parallels between phylogeny and ontogeny have been discussed for
almost two cen...
http://links.ealert.nature.com/ctt?kn=105&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Interdependence of behavioural variability and response to small
stimuli in bacteria
Heungwon Park, William Pontius, Calin C. Guet, John F. Marko,
Thierry Emonet et al.
The chemotaxis signalling network in Escherichia coli that controls
the locomot...
http://links.ealert.nature.com/ctt?kn=46&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Tumour vascularization via endothelial differentiation of
glioblastoma stem-like cells
Lucia Ricci-Vitiani, Roberto Pallini, Mauro Biffoni, Matilde Todaro,
Gloria Invernici et al.
Glioblastoma is a highly angiogenetic malignancy, the neoformed
vessels of whic...
http://links.ealert.nature.com/ctt?kn=42&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Glioblastoma stem-like cells give rise to tumour endothelium
Rong Wang, Kalyani Chadalavada, Jennifer Wilshire, Urszula Kowalik,
Koos E. Hovinga et al.
Glioblastoma (GBM) is among the most aggressive of human cancers.
A key feature...
http://links.ealert.nature.com/ctt?kn=43&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Calcium-dependent phospholipid scrambling by TMEM16F
Jun Suzuki, Masato Umeda, Peter J. Sims and Shigekazu Nagata
In all animal cells, phospholipids are asymmetrically distributed
between the o...
http://links.ealert.nature.com/ctt?kn=37&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Design, function and structure of a monomeric ClC transporter
Janice L. Robertson, Ludmila Kolmakova-Partensky and
Christopher Miller
Channels and transporters of the ClC family cause the transmembrane
movement of...
http://links.ealert.nature.com/ctt?kn=39&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** A selective role for dopamine in stimulus-reward learning
Shelly B. Flagel, Jeremy J. Clark, Terry E. Robinson, Leah Mayo,
Alayna Czuj et al.
Individuals make choices and prioritize goals using complex processes
that assi...
http://links.ealert.nature.com/ctt?kn=40&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Robust multicellular computing using genetically encoded NOR gates
and chemical 'wires'
Alvin Tamsir, Jeffrey J. Tabor and Christopher A. Voigt
Computation underlies the organization of cells into higher-order
structures, f...
http://links.ealert.nature.com/ctt?kn=41&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Subtypes of medulloblastoma have distinct developmental origins
Paul Gibson, Yiai Tong, Giles Robinson, Margaret C. Thompson,
D. Spencer Currle et al.
Medulloblastoma encompasses a collection of clinically and
molecularly diverse ...
http://links.ealert.nature.com/ctt?kn=33&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Distributed biological computation with multicellular engineered
networks
Sergi Regot, Javier Macia, Nuria Conde, Kentaro Furukawa,
Jimmy Kjellen et al.
Ongoing efforts within synthetic and systems biology have been
directed towards...
http://links.ealert.nature.com/ctt?kn=34&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Noise correlations improve response fidelity and stimulus encoding
Jon Cafaro and Fred Rieke
Computation in the nervous system often relies on the integration of
signals fr...
http://links.ealert.nature.com/ctt?kn=35&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** The mechanism of sodium and substrate release from the binding
pocket of vSGLT
Akira Watanabe, Seungho Choe, Vincent Chaptal, John M. Rosenberg,
Ernest M. Wright et al.
Membrane co-transport proteins that use a five-helix inverted repeat
motif have...
http://links.ealert.nature.com/ctt?kn=36&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Experimental niche evolution alters the strength of the
diversity-productivity relationship
Dominique Gravel, Thomas Bell, Claire Barbera, Thierry Bouvier,
Thomas Pommier et al.
The relationship between biodiversity and ecosystem functioning (BEF)
has becom...
http://links.ealert.nature.com/ctt?kn=58&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Development of asymmetric inhibition underlying direction
selectivity in the retina
Wei Wei, Aaron M. Hamby, Kaili Zhou and Marla B. Feller
Establishing precise synaptic connections is crucial to the
development of func...
http://links.ealert.nature.com/ctt?kn=56&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Impaired hydroxylation of 5-methylcytosine in myeloid cancers with
mutant TET2
Myunggon Ko, Yun Huang, Anna M. Jankowska, Utz J. Pape,
Mamta Tahiliani et al.
TET2 is a close relative of TET1, an enzyme that converts
5-methylcytosine (5mC...
http://links.ealert.nature.com/ctt?kn=57&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Evolutionary biology: Genomic hourglass
Benjamin Prud'homme and Nicolas Gompel
Comparative genomics studies reveal molecular signatures of the
controversial 'phylotypic' stage -- a time when embryos of members
of an animal phylum all look more alike than at other embryonic
stages.
http://links.ealert.nature.com/ctt?kn=54&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Cancer: Tumour stem cells switch sides
Victoria L. Bautch
Tumour stem cells are proposed to be the source of tumour cells. It
now emerges that they also give rise to the endothelial cells that
line the tumour vasculature, mediating tumour growth and metastasis.
http://links.ealert.nature.com/ctt?kn=55&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Virology: One protein, many functions
Felix A. Rey
The Lassa virus nucleoprotein coats the viral genome to make a
template for RNA synthesis. A study shows that it also binds the
'cap' structure of cellular messenger RNAs and directs immune evasion
using a novel mechanism.
http://links.ealert.nature.com/ctt?kn=52&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

NEWS & COMMENT
** Microbiology: Bacteria that thrive on arsenic
http://links.ealert.nature.com/ctt?kn=53&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Zoology: Scorpions glow to sense
http://links.ealert.nature.com/ctt?kn=50&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Neuroscience: Enzyme helps pain persist
http://links.ealert.nature.com/ctt?kn=51&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Ecology: Reptiles rose after forests died
http://links.ealert.nature.com/ctt?kn=47&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Evolution: Speaking in borrowed tongues
http://links.ealert.nature.com/ctt?kn=9&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Cancer: Full immunity needed to fight cancer
http://links.ealert.nature.com/ctt?kn=10&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Give up the ghosts
Funding agencies should make researchers reveal industry links.
http://links.ealert.nature.com/ctt?kn=93&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Lessons from Bayh-Dole
Developing countries wanting to boost commercialization of their
academic research should learn from the mistakes of US patenting
legislation, says Bhaven N. Sampat.
http://links.ealert.nature.com/ctt?kn=66&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** More for the research dollar
Funders and universities should make the products of research more
available -- even if today's researchers pay a price, say
Jeffrey L. Furman, Fiona Murray and Scott Stern.
http://links.ealert.nature.com/ctt?kn=70&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=72&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Sustainable cities: seeing past the trees
Rob MacKenzie, Tom Pugh and Chris Rogers
http://links.ealert.nature.com/ctt?kn=114&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Food-safety sentinels
Disease outbreaks in recent years have revealed the vulnerability of
food supplies. But they offer opportunities for those interested in
waging war on microbes.
http://links.ealert.nature.com/ctt?kn=137&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Turning point
Rutgers University biophysicist explains how heading overseas has
enriched his career.
http://links.ealert.nature.com/ctt?kn=101&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** British funding change
UK granting agencies aim for greater impact.
http://links.ealert.nature.com/ctt?kn=99&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Biomedical recruitment
Irish partnership gets [euro]19-million government grant for
diagnostics R&D.
http://links.ealert.nature.com/ctt?kn=96&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** More News & Comment on BIOLOGICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=104&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

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Super-Resolution Microscopy
Produced by Nature Methods

A collection of articles from several leaders in the field highlights
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developed.

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Produced with support from: Nikon
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======================== CHEMICAL SCIENCES ========================
RESEARCH
** Cap binding and immune evasion revealed by Lassa nucleoprotein
structure
Xiaoxuan Qi, Shuiyun Lan, Wenjian Wang, Lisa McLay Schelde,
Haohao Dong et al.
Lassa virus, the causative agent of Lassa fever, causes thousands of
deaths ann...
http://links.ealert.nature.com/ctt?kn=88&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Quantitative reactivity profiling predicts functional cysteines in
proteomes
Eranthie Weerapana, Chu Wang, Gabriel M. Simon, Florian Richter,
Sagar Khare et al.
Cysteine is the most intrinsically nucleophilic amino acid in
proteins, where i...
http://links.ealert.nature.com/ctt?kn=106&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

NEWS & COMMENT
** Chemistry: Ring-a-ring o'benzene
http://links.ealert.nature.com/ctt?kn=4&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Turning point
Rutgers University biophysicist explains how heading overseas has
enriched his career.
http://links.ealert.nature.com/ctt?kn=94&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** More News & Comment on CHEMICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=104&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

======================== PHYSICAL SCIENCES ========================
RESEARCH
** A lower limit of [Delta]z > 0.06 for the duration of
the reionization epoch
Judd D. Bowman and Alan E. E. Rogers
Observations of the 21-centimetre line of atomic hydrogen in the
early Universe...
http://links.ealert.nature.com/ctt?kn=82&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Snapshots of cooperative atomic motions in the optical suppression
of charge density waves
Maximilian Eichberger, Hanjo Schafer, Marina Krumova, Markus Beyer,
Jure Demsar et al.
Macroscopic quantum phenomena such as high-temperature
superconductivity, colos...
http://links.ealert.nature.com/ctt?kn=5&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Ice-sheet acceleration driven by melt supply variability
Christian Schoof
Increased ice velocities in Greenland are contributing significantly
to eustati...
http://links.ealert.nature.com/ctt?kn=6&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** A high C/O ratio and weak thermal inversion in the atmosphere of
exoplanet WASP-12b
Nikku Madhusudhan, Joseph Harrington, Kevin B. Stevenson,
Sarah Nymeyer, Christopher J. Campo et al.
The carbon-to-oxygen ratio (C/O) in a planet provides critical
information abou...
http://links.ealert.nature.com/ctt?kn=7&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Images of a fourth planet orbiting HR 8799
Christian Marois, B. Zuckerman, Quinn M. Konopacky, Bruce Macintosh
and Travis Barman
High-contrast near-infrared imaging of the nearby star HR 8799 has
shown three ...
http://links.ealert.nature.com/ctt?kn=24&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Quantum physics: Hot entanglement
Vlatko Vedral
Quantum entanglement has been observed at low temperatures in both
microscopic and macroscopic systems. It now seems that the effect
can also occur at high temperatures if the systems are not in thermal
equilibrium.
http://links.ealert.nature.com/ctt?kn=28&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Cosmology: Hydrogen was not ionized abruptly
Jonathan Pritchard and Abraham Loeb
When and how the first stars and galaxies ionized the primordial
hydrogen atoms that filled the early Universe is not known.
Observations with a single radio antenna are opening a new window on
the process.
http://links.ealert.nature.com/ctt?kn=29&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Solar system: Pluto is again a harbinger
S. Alan Stern
New astronomical and laboratory data show that the abundances of the
two dominant ices, nitrogen and methane, on the surfaces of the Solar
System's two largest dwarf planets are surprisingly similar --
raising fresh questions.
http://links.ealert.nature.com/ctt?kn=26&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Glaciology: Greenland's glacial basics
Martin P. Luthi
Sliding of the Greenland ice sheet is affected by the production of
surface meltwater. A new theory shows that whether the result is a
long-term speed-up or slow-down of ice motion depends on the
variability in melt input.
http://links.ealert.nature.com/ctt?kn=27&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

NEWS & COMMENT
** Astronomy: Stars reach their limits
http://links.ealert.nature.com/ctt?kn=19&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Materials science: Antiseptic silver slivers
http://links.ealert.nature.com/ctt?kn=20&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Optics: Taking wing on a beam of light
http://links.ealert.nature.com/ctt?kn=17&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Biography: The ABC of computing
An engaging biography of John Atanasoff reveals the obscure origins
of the computer, explains John Gilbey.
http://links.ealert.nature.com/ctt?kn=69&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=72&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Sculpture: Engineering art
Neil Dodgson admires the technical mastery of sculptor Anish Kapoor.
http://links.ealert.nature.com/ctt?kn=71&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Michael Tinkham (1928-2010)
Physicist who helped to unravel the mysteries of superconductivity.
http://links.ealert.nature.com/ctt?kn=97&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** More News & Comment on PHYSICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=104&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

======================== EARTH AND ENVIRONMENTAL SCIENCES ========================
RESEARCH
** Ice-sheet acceleration driven by melt supply variability
Christian Schoof
Increased ice velocities in Greenland are contributing significantly
to eustati...
http://links.ealert.nature.com/ctt?kn=6&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Outer-core compositional stratification from observed core wave
speed profiles
George Helffrich and Satoshi Kaneshima
Light elements must be present in the nearly pure iron core of the
Earth to mat...
http://links.ealert.nature.com/ctt?kn=18&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Global systematics of arc volcano position
Philip C. England and Richard F. Katz
Arising from Grove, T. et al. Nature 459 694-697 (2009);
Grove et al. r...
Global systematics in the location of volcanic arcs above subduction
zones are ...
http://links.ealert.nature.com/ctt?kn=21&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Grove et al. reply
T. L. Grove, C. B. Till, E. Lev, N. Chatterjee and E. Medard
Replying to England, P. C. & Katz, R. F....
http://links.ealert.nature.com/ctt?kn=142&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

NEWS & COMMENT
** Books in brief
http://links.ealert.nature.com/ctt?kn=72&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Ease public concern over oil pipeline
John B. Gates
http://links.ealert.nature.com/ctt?kn=113&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** More News & Comment on EARTH AND ENVIRONMENTAL SCIENCES
http://links.ealert.nature.com/ctt?kn=104&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

======================== Specials - Technology Feature: ========================
** Protein-protein interactions: Interactome under construction
Laura Bonetta
Developing techniques are helping researchers to build the protein
interaction ...
http://links.ealert.nature.com/ctt?kn=89&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Protein-protein interactions: Tools for the search
http://links.ealert.nature.com/ctt?kn=91&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Protein-protein interactions: Real-time analysis
http://links.ealert.nature.com/ctt?kn=79&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Protein-protein interactions: Table of suppliers
http://links.ealert.nature.com/ctt?kn=67&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

=========================== ADVERTISEMENT ===========================
Integrated Biology Poster and Reprint Collection

Nature Publishing Group presents a Poster from Nature Genetics and
a Reprint Collection of articles from Nature, Nature Biotechnology,
Nature Reviews Genetics and Nature Methods that provides guideposts
for integrated approaches to studying biology.

Access the Collection and Poster at:
http://links.ealert.nature.com/ctt?kn=132&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

Produced with support from:
Agilent Technologies
=====================================================================

======================== CAREERS & JOBS ========================
** Food-safety sentinels
Disease outbreaks in recent years have revealed the vulnerability of
food supplies. But they offer opportunities for those interested in
waging war on microbes.
http://links.ealert.nature.com/ctt?kn=109&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Turning point
Rutgers University biophysicist explains how heading overseas has
enriched his career.
http://links.ealert.nature.com/ctt?kn=107&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** British funding change
UK granting agencies aim for greater impact.
http://links.ealert.nature.com/ctt?kn=145&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Biomedical recruitment
Irish partnership gets [euro]19-million government grant for
diagnostics R&D.
http://links.ealert.nature.com/ctt?kn=144&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Youth fires innovation
Acting on council's recommendations would mean more jobs and funds
for young researchers in Europe.
http://links.ealert.nature.com/ctt?kn=143&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Singapore's salad days are over
Uncertainty has replaced confidence as economic reality bites science
in the city-state and scientists find that their research funds now
come with strings attached.
http://links.ealert.nature.com/ctt?kn=83&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Give up the ghosts
Funding agencies should make researchers reveal industry links.
http://links.ealert.nature.com/ctt?kn=93&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Food: A taste of things to come?
Researchers are sure that they can put lab-grown meat on the menu
— if they can just get cultured muscle cells to bulk up.
http://links.ealert.nature.com/ctt?kn=139&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Time to underpin Wikipedia wisdom
Alex Bateman and Darren W. Logan
http://links.ealert.nature.com/ctt?kn=90&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Guest authors: for contributors only
Mark J. van Raaij
http://links.ealert.nature.com/ctt?kn=103&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

** Guest authors: no place in any journal
Richard M. Glass
http://links.ealert.nature.com/ctt?kn=100&m=36064988&r=MjA1NzcwMjE4MQS2&b=2&j=ODkyMDYxMTYS1&mt=1&rt=0

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The EDGE

Wednesday, December 8, 2010

Nature contents: 9 December 2010

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