Nature Structural & Molecular Biology Contents: 2018 Volume #25 issue #11

TABLE OF CONTENTS November 2018 Volume 25, Issue 11 Correspondence News & Views Meeting Reports Review Articles Articles Amendments & Corrections Correspondence Misreading chaperone–substrate complexes from random noise    pp989 - 990 Jimin Wang doi:10.1038/s41594-018-0144-3 Reply to 'Misreading chaperone–substrate complexes from random noise'    pp990 - 991 Scott Horowitz, Loïc Salmon, Philipp Koldewey, Logan S. Ahlstrom, Raoul Martin et al. doi:10.1038/s41594-018-0145-2 News & Views σ1 Receptor ligand binding: an open-and-shut case    pp992 - 993 Felix J. Kim & Gavril W. Pasternak doi:10.1038/s41594-018-0146-1 Mapping the diploid genome, one cell at a time    pp994 - 995 Blake A. Caldwell & Marisa S. Bartolomei doi:10.1038/s41594-018-0149-y Structural & Molecular Biology EVENT Molecular Diagnostics World Summit London 2018 - MolrDIAx 22.11.18 London, UK More science events from Meeting Reports Life of proteins: from nascent chain to degradation    pp996 - 999 Johannes M. Herrmann, Pedro Carvalho, Manajit Hayer-Hartl & Tohru Yoshihisa doi:10.1038/s41594-018-0150-5 Review Articles Cross-linking mass spectrometry: methods and applications in structural, molecular and systems biology    pp1000 - 1008 Francis J. O'Reilly & Juri Rappsilber doi:10.1038/s41594-018-0147-0 Cross-linking mass spectrometry has developed into a robust and flexible tool that provides medium-resolution structural information. This review highlights notable successes of this technique and discusses common pipelines. Organellar TRP channels    pp1009 - 1018 Xiaoli Zhang, Meiqin Hu, Yexin Yang & Haoxing Xu doi:10.1038/s41594-018-0148-z In this Review, Haoxing Xu and colleagues summarize current knowledge of TRP channels and their roles in the response to environmental and cellular signals, focusing in particular on the least known class, the organellar TRPs. Articles A novel class of microRNA-recognition elements that function only within open reading frames    pp1019 - 1027 Kai Zhang, Xiaorong Zhang, Zhiqiang Cai, Jie Zhou, Ran Cao et al. doi:10.1038/s41594-018-0136-3 A new class of miRNA-recognition elements that function exclusively in protein-coding regions use distinct target-recognition rules and mediate translational repression instead of mRNA destabilization. De novo design of a non-local β-sheet protein with high stability and accuracy    pp1028 - 1034 Enrique Marcos, Tamuka M. Chidyausiku, Andrew C. McShan, Thomas Evangelidis, Santrupti Nerli et al. doi:10.1038/s41594-018-0141-6 Baker, Marcos and colleagues analyze β-arches (loops connecting unpaired β-strands) and derive rules used for de novo design of a hyperthermostable jellyroll structure, with eight antiparallel β-strands forming double-stranded β-helices. SAMMSON fosters cancer cell fitness by concertedly enhancing mitochondrial and cytosolic translation    pp1035 - 1046 Roberto Vendramin, Yvessa Verheyden, Hideaki Ishikawa, Lucas Goedert, Emilien Nicolas et al. doi:10.1038/s41594-018-0143-4 The lncRNA SAMMSON promotes a balanced increase in rRNA maturation and protein synthesis in the cytosol and mitochondria by modulating the localization of CARF, which affects two rRNA-processing factors. DNA damage-induced cell death relies on SLFN11-dependent cleavage of distinct type II tRNAs    pp1047 - 1058 Manqing Li, Elaine Kao, Dane Malone, Xia Gao, Jean Y. J. Wang et al. doi:10.1038/s41594-018-0142-5 SLFN11 sensitizes cancer cells to therapeutic drugs by selectively catalyzing the cleavage of Leu-TAA and Leu-AAG tRNAs in response to camptothecin DDA treatment, thereby inhibiting the translation rate of proteins enriched for these codons. Amendments & Corrections Publisher Correction: NMD-degradome sequencing reveals ribosome-bound intermediates with 3′-end non-templated nucleotides    p1059 Tatsuaki Kurosaki, Keita Miyoshi, Jason R. Myers & Lynne E. Maquat doi:10.1038/s41594-018-0153-2 Advertisement Nature Briefing is an essential round-up of science news, opinion and analysis, free in your inbox every weekday. With Nature Briefing, we'll keep you updated on the latest research, so you can focus on yours. Click here to sign up.   Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here. Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. For event advertising opportunities across the Nature Publishing Group portfolio please contact natureevents@nature.com More Nature Events

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