Nature Biotechnology Contents: Volume 36 pp 555 - 666

If you are unable to see the message below, click here to view.

Advertisement On the Pathway to Discovery, All Signals Are Clear What if you could get high quality results without the hassle? Our wide range of assay solutions makes it easier to take an orthogonal approach to your cell-based assays, glean more biologically relevant information, and get to breakthroughs faster. Learn More. TABLE OF CONTENTS July 2018 Volume 36, Issue 7 Editorial News Correspondence Feature News and Views Research Careers and Recruitment Corrigenda Errata   Advertisement   Elucidate complex cellular pathways within 2D and 3D cellular structures in response to chemical stimulation. Our high-throughput ImageXpress® imaging portfolio expedites your studies with new tools to better understand complex imaging models.  Download eBook: Cellular Imaging Insights >   Advertisement BIOPHARMA DEALMAKERS Company Profiles and Partnering Opportunities   Advertisement KACST Impact KACST Impact is a new online publication highlighting the latest cutting edge scientific research conducted at King Abdulaziz City for Science and Technology (KACST) that features various stories ranging from exciting new scientific finds to the commercialization of innovative discoveries.  Learn more   Editorial   Wanted: a reward for antibiotic development    p555 doi:10.1038/nbt.4193 News   Drug designers embrace cryo-EM    pp557 - 558 Michael Eisenstein doi:10.1038/nbt0718-557 Golden Rice is safe to eat, says FDA    pp559 - 560 Brian Owens doi:10.1038/nbt0718-559a First migraine-prevention antibody approved    p559 doi:10.1038/nbt0718-559b New money flows to CARB-X for antimicrobials    p560 doi:10.1038/nbt0718-560 Clinical trials go virtual, big pharma dives in    pp561 - 562 Eric Smalley doi:10.1038/nbt0718-561 CRISPR gene therapy trial on hold    p562 doi:10.1038/nbt0718-562 Merck vaccine heads Ebola countermeasures    pp563 - 565 Cormac Sheridan doi:10.1038/nbt0718-563a Gates unveils biotech-within-a-charity    p563 doi:10.1038/nbt0718-563b Saying aye to the artificial iris    p565 doi:10.1038/nbt0718-565 Advertisement Benchtop Linear MALDI-TOF Mass Spec  Providing a dependable, robust, and easy-to-maintain platform, Shimadzu?s benchtop MALDI-8020 delivers sensitive detection and accurate mass determination by MALDI-TOF MS for routine analysis. Intuitive software simplifies operation and enables 21 CFR Part 11 compliance. Learn more.   Correspondence   KBase: The United States Department of Energy Systems Biology Knowledgebase    pp566 - 569 Adam P Arkin, Robert W Cottingham, Christopher S Henry, Nomi L Harris, Rick L Stevens et al. doi:10.1038/nbt.4163 The 160K Natural Organism Library, a unique resource for natural products research    pp570 - 573 Siew Bee Ng, Yoganathan Kanagasundaram, Hao Fan, Prakash Arumugam, Birgit Eisenhaber et al. doi:10.1038/nbt.4187 The European Union Court's Advocate General's Opinion and new plant breeding techniques    pp573 - 575 Kai P Purnhagen, Esther Kok, Gijs Kleter, Hanna Schebesta, Richard G F Visser et al. doi:10.1038/nbt.4174 Advertisement Synthetic Biology - Resource Allocation in Natural and Unnatural Systems  This nature conference will address the issue of resource allocation from several perspectives from design to implementation, explore current challenges and examine the approaches that are being taken to overcome these challenges. October 15-17, 2018 | Shanghai, China   Feature   Public biotech in 2017—the numbers    pp576 - 584 Chris Morrison & Riku Lähteenmäki doi:10.1038/nbt.4175 Patents Patent mining and landscaping of emerging recombinant factor VIII through network analysis    pp585 - 590 Cristiano Gonçalves Pereira, Virgínia Picanco-Castro, Dimas Tadeu Covas & Geciane Silveira Porto doi:10.1038/nbt.4178 Recent patents in organoids and organs-on-chips    p591 doi:10.1038/nbt.4190 News and Views   Cardiomyocytes remuscularize the heart    pp592 - 593 Wolfram-Hubertus Zimmermann doi:10.1038/nbt.4186 A new route to synthetic DNA    pp593 - 595 Adam Clore doi:10.1038/nbt.4185 Research Highlights    p595 doi:10.1038/nbt.4176 Reportage from the gut    p596 Irene Jarchum doi:10.1038/nbt.4177 Biotechnology JOBS of the week Assistant / Associate Professor, Tenure Track New York University School of Medicine Postdoctoral Research Fellowship Johns Hopkins University (JHU) Postdoctoral positions in Neuroscience Thomas Jefferson University (TJU) Tenure-Track Faculty Positions Ohio State University Postdoctoral Fellow- Immunology NYU Langone Health More Science jobs from Biotechnology EVENT International Colloquium on Biotechnology & Industrial Revolution 15.11.18 Dubai, UAE More science events from Research   Articles Human embryonic stem cell–derived cardiomyocytes restore function in infarcted hearts of non-human primates    pp597 - 605 Yen-Wen Liu, Billy Chen, Xiulan Yang, James A Fugate, Faith A Kalucki et al. doi:10.1038/nbt.4162 Cardiomyocyte transplantation after heart attack improves contractile function in monkeys. Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass    pp606 - 613 Ruwan Gunaratne, Shekhar Kumar, James W Frederiksen, Steven Stayrook, Jens L Lohrmann et al. doi:10.1038/nbt.4153 An aptamer is combined with a drug to prevent clot formation in a model of cardiopulmonary bypass. Precise, automated control of conditions for high-throughput growth of yeast and bacteria with eVOLVER    pp614 - 623 doi:10.1038/nbt.4151 Continuous culturing of individually controlled growth experiments in parallel and at high-throughput is enabled with an automated DIY platform. Custom selenoprotein production enabled by laboratory evolution of recoded bacterial strains    pp624 - 631 Ross Thyer, Raghav Shroff, Dustin R Klein, Simon d'Oelsnitz, Victoria C Cotham et al. doi:10.1038/nbt.4154 Selenocysteine is efficiently incorporated into recombinant proteins using evolved Escherichia coli strains. Letters Efficient generation of targeted large insertions by microinjection into two-cell-stage mouse embryos    pp632 - 637 Bin Gu, Eszter Posfai & Janet Rossant doi:10.1038/nbt.4166 Knock-in mice with precise insertions are efficiently generated through delivery of CRISPR–Cas9 to two-cell embryos. Encoding human serine phosphopeptides in bacteria for proteome-wide identification of phosphorylation-dependent interactions    pp638 - 644 Karl W Barber, Paul Muir, Richard V Szeligowski, Svetlana Rogulina, Mark Gerstein et al. doi:10.1038/nbt.4150 Screening with bacteria encoding human serine phosphopeptides reveals phosphoprotein interactions. De novo DNA synthesis using polymerase-nucleotide conjugates    pp645 - 650 Sebastian Palluk, Daniel H Arlow, Tristan de Rond, Sebastian Barthel, Justine S Kang et al. doi:10.1038/nbt.4173 An enzymatic approach enables synthesis of a defined DNA sequence using TdT with reversibly tethered dNTPs.   Immune-centric network of cytokines and cells in disease context identified by computational mining of PubMed    pp651 - 659 Ksenya Kveler, Elina Starosvetsky, Amit Ziv-Kenet, Yuval Kalugny, Yuri Gorelik et al. doi:10.1038/nbt.4152 Interactions between hundreds of immune cells and cytokines in disease are mined from PubMed. Careers and Recruitment   As life sciences sector's positive momentum continues, so do executive compensation levels    pp661 - 664 Bruce Rychlik doi:10.1038/nbt.4188 People People    p666 doi:10.1038/nbt.4191 Corrigenda   Corrigendum: Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea    p660 Robert M Bowers, Nikos C Kyrpides, Ramunas Stepanauskas, Miranda Harmon-Smith, Devin Doud et al. doi:10.1038/nbt0718-660a Corrigendum: Assisted reproductive technologies to prevent human mitochondrial disease transmission    p660 Andy Greenfield, Peter Braude, Frances Flinter, Robin Lovell-Badge, Caroline Ogilvie et al. doi:10.1038/nbt0718-660b Errata   Erratum: Random access in large-scale DNA data storage    p660 Lee Organick, Siena Dumas Ang, Yuan-Jyue Chen, Randolph Lopez, Sergey Yekhanin et al. doi:10.1038/nbt0718-660c Erratum: California voters and CIRM—will lightning strike twice?    p660 Laura DeFrancesco doi:10.1038/nbt0718-660d Advertisement Nature Briefing is an essential round-up of science news, opinion and analysis, free in your inbox every weekday. With Nature Briefing, we'll keep you updated on the latest research, so you can focus on yours. Click here to sign up.   Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here. Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. For event advertising opportunities across the Nature Publishing Group portfolio please contact natureevents@nature.com More Nature Events

You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/myaccount (You will need to log in to be recognised as a nature.com registrant) For further technical assistance, please contact our registration department For print subscription enquiries, please contact our subscription department For other enquiries, please contact our customer feedback department Springer Nature | One New York Plaza, Suite 4500 | New York | NY 10004-1562 | USA Springer Nature's worldwide offices: London - Paris - Munich - New Delhi - Tokyo - Melbourne San Diego - San Francisco - Washington - New York - Boston Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at The Campus, 4 Crinan Street, London, N1 9XW. © 2018 Macmillan Publishers Limited, part of Springer Nature. All Rights Reserved.