Monday, May 14, 2018

Nature Reviews Microbiology contents June 2018 Volume 16 Number 6

Nature Reviews Microbiology

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June 2018 Volume 16, Issue 6

Research Highlights
News & Analysis
Amendments & Corrections

Research Highlights


To grow, or not to grow    p329
Ursula Hofer

Two large culture screens of the gut microbiota study the effects of defined media and drugs on bacterial growth.


The STING behind dengue virus infection    p330
Katharine Wrighton

Finding IRESs in mycoviruses    p330
Katharine Wrighton

Nanowires under the microscope    p330
Katharine Wrighton

Blasting through cells    pp330 - 331
Andrea Du Toit

This study reports that the mitogen-activated protein kinase pathway controls plant tissue invasion by Magnaporthe oryzae through the control of hyphal constriction and the expression of effectors to suppress plant immunity.


Treading the same path    pp330 - 331
Ashley York

A new study reports the discovery of 214 RNA viruses from diverse vertebrates that reveal new insights into host–virus relationships across evolutionary timescales.


A dormant state within cells    p331

At the end of KSHV’s tether    p331

Assessing chromatin accessibility    p331

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News & Analysis


Juggling resistance mutations    p332
Gavin G. Rutledge & Roberto Amato



CRISPR-based genomic tools for the manipulation of genetically intractable microorganisms    pp333 - 339
Rebecca S. Shapiro, Alejandro Chavez & James J. Collins

In this Progress article, Collins and colleagues discuss how CRISPR-based analyses in genetically intractable microorganisms, including mycobacteria, fungi and parasites, have enabled the discovery of novel gene functions, the investigation of genetic interaction networks and the identification of virulence factors.




Autophagy during viral infection — a double-edged sword    pp341 - 354
Younho Choi, James W. Bowman & Jae U. Jung

Autophagy is crucial for innate and adaptive antiviral immunity; in turn, viruses evade and subvert autophagy to support their replication and pathogenesis. In this Review, Choi, Bowman and Jung discuss the molecular mechanisms that govern autophagy during host–virus interactions.


Streptococcus pneumoniae: transmission, colonization and invasion    pp355 - 367
Jeffrey N. Weiser, Daniela M. Ferreira & James C. Paton

Carriage of Streptococcus pneumoniae on the mucosa of the upper respiratory tract is the prerequisite for transmission and tissue invasion. In this Review, Weiser, Ferreira and Paton summarize the mechanisms that allow pneumococci to transmit and progress from colonizer to pathogen.


The life cycle of non-polio enteroviruses and how to target it    pp368 - 381
Jim Baggen, Hendrik Jan Thibaut, Jeroen R. P. M. Strating & Frank J. M. van Kuppeveld

In recent years, several non-polio enteroviruses (NPEVs) have emerged as serious public health concerns. In this Review, van Kuppeveld and colleagues summarize recent insights from enterovirus research, with a special emphasis on NPEVs, and reflect on how recent discoveries may help in the development of new antiviral strategies.




The social network of microorganisms — how auxotrophies shape complex communities    pp383 - 390
Karsten Zengler & Livia S. Zaramela

Interactions among organisms are not limited to the exchange of electron donors. Most microorganisms are auxotrophs and thus rely on external nutrients for growth. In this Opinion article, Zengler and Zaramela postulate that auxotrophies and nutrient requirements among members of complex communities have profound implications for microbial interactions and thus the overall microbial network.


Amendments & Corrections


Publisher Correction: The life cycle of non-polio enteroviruses and how to target it    p391
Jim Baggen, Hendrik Jan Thibaut, Jeroen R. P. M. Strating & Frank J. M. van Kuppeveld

Correction: Bridging the gap for lipopolysaccharides    p391
Katharine H. Wrighton

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