| ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase ANKRD16 attenuates neurodegeneration induced by a mutation in the editing domain of alanyl tRNA synthetase by directly accepting mis-activated serine from the synthetase before transfer to the tRNA, establishing a new mechanism by which editing defects are prevented. My-Nuong Vo, Markus Terrey, Jeong Woong Lee et al. | | | An absolute sodium abundance for a cloud-free ‘hot Saturn’ exoplanet The optical transmission spectrum for the ‘hot Saturn’ exoplanet WASP-96b reveals a clear atmosphere, an atmospheric sodium abundance and hence its metallicity, which is consistent with the metallicity trend observed in Solar System planets and exoplanets. N. Nikolov, D. K. Sing, J. J. Fortney et al. | | Fundamental limits to graphene plasmonics The fundamental limits to plasmon damping in graphene are determined using nanoscale infrared imaging at cryogenic temperatures, and plasmon polaritons are observed to propagate over 10 micrometres in high-mobility encapsulated graphene. G. X. Ni, A. S. McLeod, Z. Sun et al. | | Self-reporting and self-regulating liquid crystals Liquid crystals are used to self-report and self-regulate either continuous or transient release of droplets or microparticles trapped within them in response to thermal, chemical, mechanical or biological stimuli. Young-Ki Kim, Xiaoguang Wang, Pranati Mondkar et al. | | Inference of ecological and social drivers of human brain-size evolution Using estimates of metabolic costs of the brain and body, mathematical predictions suggest that the evolution of adult Homo sapiens-sized brains and bodies is driven by ecological rather than social challenges and is perhaps strongly promoted by culture. Mauricio González-Forero, Andy Gardner | | Mxra8 is a receptor for multiple arthritogenic alphaviruses The cell adhesion molecule Mxra8 is identified as a receptor for multiple arthritogenic alphaviruses such as chikungunya virus, and anti-Mxra8 monoclonal antibodies are shown to reduce rates of chikungunya virus infection in mice and a range of human cells. Rong Zhang, Arthur S. Kim, Julie M. Fox et al. | | Structural basis for gating pore current in periodic paralysis Crystal structures and molecular dynamics simulations of voltage-gated sodium channels containing mutations that cause hypokalaemic and normokalaemic periodic paralysis indicate the pathogenic mechanisms of these conditions and suggest a target for the design of potential therapeutic and symptomatic drugs. Daohua Jiang, Tamer M. Gamal El-Din, Christopher Ing et al. | | | | | |
No comments:
Post a Comment