TABLE OF CONTENTS
|  |  |  | | Volume 32, Issue 3 (March 2018) |  | In this issue Original Articles Letters to the Editor Also new AOP | |  |  |  | Original Articles |  |  |  | | Acute myeloid leukemia |  | Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion B Kumar, M Garcia, L Weng, X Jung, J L Murakami et al. Leukemia 2017 32 :575 - 587; August 17, 2017; 10.1038/leu.2017.259 Abstract | Full Text |  |  |  |  | Interleukin 4 induces apoptosis of acute myeloid leukemia cells in a Stat6-dependent manner P Peña-Martínez, M Eriksson, R Ramakrishnan, M Chapellier, C Högberg et al. Leukemia 2017 32 :588 - 596; August 18, 2017; 10.1038/leu.2017.261 Abstract | Full Text |  |  |  |  | RSK2 is a new Pim2 target with pro-survival functions in FLT3-ITD-positive acute myeloid leukemia M-A Hospital, A Jacquel, F Mazed, E Saland, C Larrue et al. Leukemia 2017 32 :597 - 605; September 15, 2017; 10.1038/leu.2017.284 Abstract | Full Text |  | | Acute lymphoblastic leukemia |  | Results of NOPHO ALL2008 treatment for patients aged 145 years with acute lymphoblastic leukemia N Toft, H Birgens, J Abrahamsson, L Grikevicius, H Hallböök et al. Leukemia 2017 32 :606 - 615; August 18, 2017; 10.1038/leu.2017.265 Abstract | Full Text |  |  |  |  | Targeting the vulnerability to NAD+ depletion in B-cell acute lymphoblastic leukemia S Takao, W Chien, V Madan, D-C Lin, L-W Ding et al. Leukemia 2017 32 :616 - 625; September 14, 2017; 10.1038/leu.2017.281 Abstract | Full Text |  |  |  |  | High-dose methotrexate therapy significantly improved survival of adult acute lymphoblastic leukemia: a phase III study by JALSG T Sakura, F Hayakawa, I Sugiura, T Murayama, K Imai et al. Leukemia 2017 32 :626 - 632; September 15, 2017; 10.1038/leu.2017.283 Abstract | Full Text |  |  |  |  | NG2 antigen is involved in leukemia invasiveness and central nervous system infiltration in MLL-rearranged infant B-ALL C Prieto, B López-Millán, H Roca-Ho, R W Stam, D Romero-Moya et al. Leukemia 2017 32 :633 - 644; September 25, 2017; 10.1038/leu.2017.294 Abstract | Full Text |  | | Chronic lymphocytic leukemia |  | Clinical impact of the subclonal architecture and mutational complexity in chronic lymphocytic leukemia F Nadeu, G Clot, J Delgado, D Martín-García, T Baumann et al. Leukemia 2017 32 :645 - 653; September 19, 2017; 10.1038/leu.2017.291 Abstract | Full Text |  |  |  |  | NOTCH1 mutations are associated with high CD49d expression in chronic lymphocytic leukemia: link between the NOTCH1 and the NF-?B pathways D Benedetti, E Tissino, F Pozzo, T Bittolo, C Caldana et al. Leukemia 2017 32 :654 - 662; September 22, 2017; 10.1038/leu.2017.296 Abstract | Full Text |  | | Lymphoma |  | Targeting nucleolin for better survival in diffuse large B-cell lymphoma N Jain, H Zhu, T Khashab, Q Ye, B George et al. Leukemia 2017 32 :663 - 674; July 10, 2017; 10.1038/leu.2017.215 Abstract | Full Text |  |  |  |  | Integrating genomic alterations in diffuse large B-cell lymphoma identifies new relevant pathways and potential therapeutic targets K Karube, A Enjuanes, I Dlouhy, P Jares, D Martin-Garcia et al. Leukemia 2017 32 :675 - 684; August 14, 2017; 10.1038/leu.2017.251 Abstract | Full Text |  |  |  |  | Differences between BCL2-break positive and negative follicular lymphoma unraveled by whole-exome sequencing A Zamò, J Pischimarov, M Schlesner, P Rosenstiel, R Bomben et al. Leukemia 2017 32 :685 - 693; August 21, 2017; 10.1038/leu.2017.270 Abstract | Full Text |  |  |  |  | Activation of RHOAVAV1 signaling in angioimmunoblastic T-cell lymphoma M Fujisawa, M Sakata-Yanagimoto, S Nishizawa, D Komori, P Gershon et al. Leukemia 2017 32 :694 - 702; August 23, 2017; 10.1038/leu.2017.273 Abstract | Full Text |  |  |  |  | HDAC6 regulates microRNA-27b that suppresses proliferation, promotes apoptosis and target MET in diffuse large B-cell lymphoma Y J Jia, Z B Liu, W G Wang, C B Sun, P Wei et al. Leukemia 2017 32 :703 - 711; September 28, 2017; 10.1038/leu.2017.299 Abstract | Full Text |  | | Multiple myeloma, gammopathies |  | Outcomes of maintenance therapy with lenalidomide or bortezomib in multiple myeloma in the setting of early autologous stem cell transplantation R Chakraborty, E Muchtar, S K Kumar, F K Buadi, D Dingli et al. Leukemia 2017 32 :712 - 718; August 14, 2017; 10.1038/leu.2017.256 Abstract | Full Text |  |  |  |  | Pomalidomidedexamethasone in refractory multiple myeloma: long-term follow-up of a multi-cohort phase II clinical trial S Ailawadhi, J R Mikhael, B R LaPlant, K M Laumann, S Kumar et al. Leukemia 2017 32 :719 - 728; September 01, 2017; 10.1038/leu.2017.258 Abstract | Full Text |  |  |  |  | Clinical presentation and outcomes in light chain amyloidosis patients with non-evaluable serum free light chains S Sidana, N Tandon, A Dispenzieri, M A Gertz, F K Buadi et al. Leukemia 2017 32 :729 - 735; September 18, 2017; 10.1038/leu.2017.286 Abstract | Full Text |  |  |  |  | JAM-A as a prognostic factor and new therapeutic target in multiple myeloma A G Solimando, A Brandl, K Mattenheimer, C Graf, M Ritz et al. Leukemia 2017 32 :736 - 743; September 28, 2017; 10.1038/leu.2017.287 Abstract | Full Text |  |  |  |  | 14-3-3ζ binds the proteasome, limits proteolytic function and enhances sensitivity to proteasome inhibitors Y Gu, K Xu, C Torre, M Samur, B G Barwick et al. Leukemia 2017 32 :744 - 751; September 19, 2017; 10.1038/leu.2017.288 Abstract | Full Text |  |  |  |  | Identification and characterization of HLA-A24-specific XBP1, CD138 (Syndecan-1) and CS1 (SLAMF7) peptides inducing antigens-specific memory cytotoxic T lymphocytes targeting multiple myeloma J Bae, T Hideshima, G L Zhang, J Zhou, D B Keskin et al. Leukemia 2017 32 :752 - 764; November 01, 2017; 10.1038/leu.2017.316 Abstract | Full Text |  | | Stem cell transplantation |  | Extracellular vesicles as potential biomarkers of acute graft-vs-host disease G Lia, L Brunello, S Bruno, A Carpanetto, P Omedè et al. Leukemia 2017 32 :765 - 773; August 30, 2017; 10.1038/leu.2017.277 Abstract | Full Text |  | | Molecular targets for therapy |  | Discovery of novel drug sensitivities in T-PLL by high-throughput ex vivo drug testing and mutation profiling E I Andersson, S Pützer, B Yadav, O Dufva, S Khan et al. Leukemia 2017 32 :774 - 787; August 14, 2017; 10.1038/leu.2017.252 Abstract | Full Text |  |  |  |  | Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia S Degryse, C E de Bock, S Demeyer, I Govaerts, S Bornschein et al. Leukemia 2017 32 :788 - 800; August 30, 2017; 10.1038/leu.2017.276 Abstract | Full Text |  | | Immunotherapy |  | Toll-like receptor 2 costimulation potentiates the antitumor efficacy of CAR T Cells Y Lai, J Weng, X Wei, L Qin, P Lai et al. Leukemia 2017 32 :801 - 808; August 03, 2017; 10.1038/leu.2017.249 Abstract | Full Text |  | | Transcriptional control and signal transduction, cell cycle |  | The T-cell leukemia-associated ribosomal RPL10 R98S mutation enhances JAK-STAT signaling T Girardi, S Vereecke, S O Sulima, Y Khan, L Fancello et al. Leukemia 2017 32 :809 - 819; July 24, 2017; 10.1038/leu.2017.225 Abstract | Full Text |  |  |  |  | Phosphorylation of SOS1 on tyrosine 1196 promotes its RAC GEF activity and contributes to BCR-ABL leukemogenesis S Gerboth, E Frittoli, A Palamidessi, F C Baltanas, M Salek et al. Leukemia 2017 32 :820 - 827; August 18, 2017; 10.1038/leu.2017.267 Abstract | Full Text |  |  |  |  | C-terminal BRE overexpression in 11q23-rearranged and t(8;16) acute myeloid leukemia is caused by intragenic transcription initiation A E Marneth, K H M Prange, A S A Al Hinai, S M Bergevoet, N Tesi et al. Leukemia 2017 32 :828 - 836; September 05, 2017; 10.1038/leu.2017.280 Abstract | Full Text |  | Letters to the Editor |  |  | Prognostic significance of ASXL1 mutation types and allele burden in myelofibrosis A Tefferi, T L Lasho, C Finke, N Gangat, C A Hanson et al. Leukemia 2017 32 :837 - 839; November 01, 2017; 10.1038/leu.2017.318 Abstract | Full Text |  |  |  |  | A novel genetic and morphologic phenotype of ARID2-mediated myelodysplasia H Sakai, N Hosono, H Nakazawa, B Przychodzen, C Polprasert et al. Leukemia 2017 32 :839 - 843; November 03, 2017; 10.1038/leu.2017.319 Abstract | Full Text |  |  |  |  | Combination of a novel HDAC6 inhibitor ACY-241 and anti-PD-L1 antibody enhances anti-tumor immunity and cytotoxicity in multiple myeloma A Ray, D S Das, Y Song, T Hideshima, Y-T Tai et al. Leukemia 2017 32 :843 - 846; November 06, 2017; 10.1038/leu.2017.322 Abstract | Full Text |  |  |  |  | Bruton's tyrosine kinase and RAC1 promote cell survival in MLL-rearranged acute myeloid leukemia S C Nimmagadda, S Frey, B Edelmann, C Hellmich, L Zaitseva et al. Leukemia 2017 32 :846 - 849; November 07, 2017; 10.1038/leu.2017.324 Abstract | Full Text |  |  |  |  | Genotoxic stresses promote clonal expansion of hematopoietic stem cells expressing mutant p53 S Chen, R Gao, C Yao, M Kobayashi, S Z Liu et al. Leukemia 2017 32 :850 - 854; November 16, 2017; 10.1038/leu.2017.325 Abstract | Full Text |  |  |  |  |  |  |  | Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here. Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. 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