Cell Death and Disease - Table of Contents alert Volume 9, February 2018

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TABLE OF CONTENTS Volume 9 (February 2018) In this issue Article Comment Review Article Meeting Report
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AGO1 may influence the prognosis of hepatocellular carcinoma through TGF-ß pathway Miao Wang, Lyu Zhang, Zeyang Liu, Jiamin Zhou, Qi Pan et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0338-y Abstract | Full Text
Glucose metabolism and NRF2 coordinate the antioxidant response in melanoma resistant to MAPK inhibitors Raeeka Khamari, Anne Trinh, Pierre Elliott Gabert, Paola Corazao-Rozas, Samuel Riveros-Cruz et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0340-4 Abstract | Full Text
Lysine methyltransferase SMYD2 promotes triple negative breast cancer progression Linda Xiaoyan Li, Julie Xia Zhou, James P. Calvet, Andrew K. Godwin, Roy A. Jensen et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0347-x Abstract | Full Text
Histone deacetylase inhibitors protect against cisplatin-induced acute kidney injury by activating autophagy in proximal tubular cells Jing Liu, Man J. Livingston, Guie Dong, Chengyuan Tang, Yunchao Su et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0374-7 Abstract | Full Text
Plasma exosomes induced by remote ischaemic preconditioning attenuate myocardial ischaemia/reperfusion injury by transferring miR-24 Wen Minghua, Gong Zhijian, Huang Chahua, Liang Qiang, Xu Minxuan et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0274-x Abstract | Full Text
Kupffer cell-derived TNF-a promotes hepatocytes to produce CXCL1 and mobilize neutrophils in response to necrotic cells Li Su, Na Li, Hua Tang, Ziyang Lou, Xiaodan Chong et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0377-4 Abstract | Full Text
CASC2/miR-24/miR-221 modulates the TRAIL resistance of hepatocellular carcinoma cell through caspase-8/caspase-3 Xiaoxin Jin, Lifeng Cai, Changfa Wang, Xiaofeng Deng, Shengen Yi et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0350-2 Abstract | Full Text
TCF7L2 positively regulates aerobic glycolysis via the EGLN2/HIF-1a axis and indicates prognosis in pancreatic cancer Jinfeng Xiang, Qiangsheng Hu, Yi Qin, Shunrong Ji, Wenyan Xu et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0367-6 Abstract | Full Text
Circular RNA GRB10 as a competitive endogenous RNA regulating nucleus pulposus cells death in degenerative intervertebral disk Wei Guo, Bin Zhang, Kun Mu, Shi-Qing Feng, Zhan-Yin Dong et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0232-z Abstract | Full Text
Estradiol signaling mediates gender difference in visceral adiposity via autophagy Zhipeng Tao, Louise D. Zheng, Cayleen Smith, Jing Luo, Alex Robinson et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0372-9 Abstract | Full Text
DZNep inhibits H3K27me3 deposition and delays retinal degeneration in the rd1 mice Shijie Zheng, Lirong Xiao, Yu Liu, Yujiao Wang, Lin Cheng et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0349-8 Abstract | Full Text
Role of autophagy in modulating post-maturation aging of mouse oocytes Fei-Hu Lin, Wei-Ling Zhang, Hong Li, Xiao-Dan Tian, Jie Zhang et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0368-5 Abstract | Full Text
Arginase-II activates mTORC1 through myosin-1b in vascular cell senescence and apoptosis   Cell Death & Disease 2018 9: 10.1038/s41419-018-0356-9 Abstract | Full Text
Metformin exerts multitarget antileukemia activity in JAK2V617F-positive myeloproliferative neoplasms João Agostinho Machado-Neto, Bruna Alves Fenerich, Renata Scopim-Ribeiro, Christopher A. Eide, Juan Luiz Coelho-Silva et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0256-4 Abstract | Full Text
PU.1/microRNA-142-3p targets ATG5/ATG16L1 to inactivate autophagy and sensitize hepatocellular carcinoma cells to sorafenib Kai Zhang, Jing Chen, Hao Zhou, Ying Chen, Yingru Zhi et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0344-0 Abstract | Full Text
Atm reactivation reverses ataxia telangiectasia phenotypes in vivo Sara Di Siena, Federica Campolo, Roberto Gimmelli, Chiara Di Pietro, Daniela Marazziti et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0357-8 Abstract | Full Text
PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis Bin Zhao, Lei Liu, Jun Mao, Zhiwei Zhang, Qifei Wang et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0348-9 Abstract | Full Text
Co-inhibition of BET proteins and NF-?B as a potential therapy for colorectal cancer through synergistic inhibiting MYC and FOXM1 expressions Tingyu Wu, Guanghui Wang, Wei Chen, Zhehui Zhu, Yun Liu et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0354-y Abstract | Full Text
Loss of the Drosophila m-AAA mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration Gautam Pareek, Ruth E. Thomas & Leo J. Pallanck Cell Death & Disease 2018 9: 10.1038/s41419-018-0365-8 Abstract | Full Text
IL-32 gamma reduces lung tumor development through upregulation of TIMP-3 overexpression and hypomethylation Jaesuk Yun, Mi Hee Park, Dong Ju Son, Kyung Tak Nam, Dae Bong Moon et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0375-6 Abstract | Full Text
Long glucocorticoid-induced leucine zipper regulates human thyroid cancer cell proliferation Emira Ayroldi, Maria Grazia Petrillo, Maria Cristina Marchetti, Lorenza Cannarile, Simona Ronchetti et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0346-y Abstract | Full Text
Identification of a novel microRNA-mRNA regulatory biomodule in human prostate cancer Yanqiong Zhang, Funeng Jiang, Huichan He, Jianheng Ye, Xia Mao et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0293-7 Abstract | Full Text
Embryonic lethality in mice lacking Trim59 due to impaired gastrulation development Xiaomin Su, Chenglei Wu, Xiaoying Ye, Ming Zeng, Zhujun Zhang et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0370-y Abstract | Full Text
LINC01016 promotes the malignant phenotype of endometrial cancer cells by regulating the miR-302a-3p/miR-3130-3p/NFYA/SATB1 axis Xin Pan, Da Li, Jianing Huo, Fanfei Kong, Hui Yang et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0291-9 Abstract | Full Text
ALCAM+ stromal cells: role in giant cell tumor of bone progression Zhenhua Zhou, Yan Li, Xudong Wang, Jingjing Hu, Muyu Kuang et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0361-z Abstract | Full Text
The interactome and spatial redistribution feature of Ca2+ receptor protein calmodulin reveals a novel role in invadopodia-mediated invasion Tao Li, Li Yi, Long Hai, Haiwen Ma, Zhennan Tao et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0253-7 Abstract | Full Text
Ceramide-induced BOK promotes mitochondrial fission in preeclampsia Jonathan Ausman, Joelcio Abbade, Leonardo Ermini, Abby Farrell, Andrea Tagliaferro et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0360-0 Abstract | Full Text
Contribution of TMEM16F to pyroptotic cell death Jiraporn Ousingsawat, Podchanart Wanitchakool, Rainer Schreiber & Karl Kunzelmann Cell Death & Disease 2018 9: 10.1038/s41419-018-0373-8 Abstract | Full Text
Glutamate-induced and NMDA receptor-mediated neurodegeneration entails P2Y1 receptor activation Ana P. Simões, Carla G. Silva, Joana M. Marques, Daniela Pochmann, Lisiane O. Porciúncula et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0351-1 Abstract | Full Text
Dysfunctional immunoregulation in human liver allograft rejection associated with compromised galectin-1/CD7 pathway function Sidong Wei, Ding Cao, Zuojin Liu, Jinheng Li, Hao Wu et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0220-3 Abstract | Full Text
Induction of ER and mitochondrial stress by the alkylphosphocholine erufosine in oral squamous cell carcinoma cells Shariq S. Ansari, Ashwini K. Sharma, Himanshu Soni, Doaa M. Ali, Björn Tews et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0342-2 Abstract | Full Text
GRK5 functions as an oncogenic factor in non-small-cell lung cancer Li-Ping Jiang, Song-Qing Fan, Qiu-Xia Xiong, Yong-Chun Zhou, Zuo-Zhang Yang et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0299-1 Abstract | Full Text
Long noncoding RNA Gomafu upregulates Foxo1 expression to promote hepatic insulin resistance by sponging miR-139-5p   Cell Death & Disease 2018 9: 10.1038/s41419-018-0321-7 Abstract | Full Text
Calpain7 impairs embryo implantation by downregulating ß3-integrin expression via degradation of HOXA10 Qiang Yan, Chenyang Huang, Yue Jiang, Huizhi Shan, Ruiwei Jiang et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0317-3 Abstract | Full Text
The mycotoxin phomoxanthone A disturbs the form and function of the inner mitochondrial membrane Philip Böhler, Fabian Stuhldreier, Ruchika Anand, Arun Kumar Kondadi, David Schlütermann et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0312-8 Abstract | Full Text
Light action spectrum on oxidative stress and mitochondrial damage in A2E-loaded retinal pigment epithelium cells Mélanie Marie, Karine Bigot, Claire Angebault, Coralie Barrau, Pauline Gondouin et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0331-5 Abstract | Full Text
miR-142-3p regulates autophagy by targeting ATG16L1 in thymic-derived regulatory T cell (tTreg) Chuanyong Zhang, Hongbing shen, Yunjie Lu, Ji Gao, Shaopeng Zhang et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0298-2 Abstract | Full Text
Elevated intracellular cAMP exacerbates vulnerability to oxidative stress in optic nerve head astrocytes Myoung Sup Shim, Keun-Young Kim, Jung Hyun Bu, Hye Seung Nam, Seung Won Jeong et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0171-8 Abstract | Full Text
Erythrocyte glutathione transferase in kidney transplantation: a probe for kidney detoxification efficiency Alessio Bocedi, Annalisa Noce, Valentina Rovella, Giulia Marrone, Giada Cattani et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0289-3 Abstract | Full Text
ALS-related human cortical and motor neurons survival is differentially affected by Sema3A   Cell Death & Disease 2018 9: 10.1038/s41419-018-0294-6 Abstract | Full Text
Gambogenic acid inhibits fibroblast growth factor receptor signaling pathway in erlotinib-resistant non-small-cell lung cancer and suppresses patient-derived xenograft growth Linfeng Xu, Xiaoxiao Meng, Naihan Xu, Wenwei Fu, Hongsheng Tan et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0314-6 Abstract | Full Text
NIT1 suppresses tumour proliferation by activating the TGFß1–Smad2/3 signalling pathway in colorectal cancer Chun Lin, Jianming Zhang, Yanxia Lu, Xiaomin Li, Wenjuan Zhang et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0333-3 Abstract | Full Text
CRISPR whole-genome screening identifies new necroptosis regulators and RIPK1 alternative splicing Marinella G. Callow, Colin Watanabe, Katherine E. Wickliffe, Russell Bainer, Sarah Kummerfield et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0301-y Abstract | Full Text
Norisoboldine, a natural AhR agonist, promotes Treg differentiation and attenuates colitis via targeting glycolysis and subsequent NAD+/SIRT1/SUV39H1/H3K9me3 signaling pathway Qi Lv, Kai Wang, Simiao Qiao, Ling Yang, Yirong Xin et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0297-3 Abstract | Full Text
Long noncoding RNA MEG3 suppresses liver cancer cells growth through inhibiting ß-catenin by activating PKM2 and inactivating PTEN Qidi Zheng, Zhuojia Lin, Jie Xu, Yanan Lu, Qiuyu Meng et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0305-7 Abstract | Full Text
Cinacalcet-mediated activation of the CaMKKß-LKB1-AMPK pathway attenuates diabetic nephropathy in db/db mice by modulation of apoptosis and autophagy Ji Hee Lim, Hyung Wook Kim, Min Young Kim, Tae Woo Kim, Eun Nim Kim et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0324-4 Abstract | Full Text
The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity Jose M. Mellado-Gil, Esther Fuente-Martín, Petra I. Lorenzo, Nadia Cobo-Vuilleumier, Livia López-Noriega et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0272-z Abstract | Full Text
Non-alcoholic fatty liver disease severity is modulated by transglutaminase type 2 Mauro Piacentini, Andrea Baiocchini, Franca Del Nonno, Gerry Melino, Nickolai A. Barlev et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0292-8 Abstract | Full Text
Predictive and preventive significance of AMPK activation on hepatocarcinogenesis in patients with liver cirrhosis Xiaoli Yang, Yan Liu, Menghui Li, Hao Wu, Yunbing Wang et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0308-4 Abstract | Full Text
The pro-inflammatory phenotype of the human non-classical monocyte subset is attributed to senescence Siew-Min Ong, Eva Hadadi, Truong-Minh Dang, Wei-Hseun Yeap, Crystal Tze-Ying Tan et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0327-1 Abstract | Full Text
Nuclear factor 90 promotes angiogenesis by regulating HIF-1a/VEGF-A expression through the PI3K/Akt signaling pathway in human cervical cancer Wenqian Zhang, Zhengai Xiong, Tianqin Wei, Qiumeng Li, Ying Tan et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0334-2 Abstract | Full Text
Senescence-associated secretory factors induced by cisplatin in melanoma cells promote non-senescent melanoma cell growth through activation of the ERK1/2-RSK1 pathway Xuerong Sun, Benyan Shi, Huiling Zheng, Ling Min, Jie Yang et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0303-9 Abstract | Full Text
EGFR-PI3K-PDK1 pathway regulates YAP signaling in hepatocellular carcinoma: the mechanism and its implications in targeted therapy Hongwei Xia, Xinyu Dai, Huangfei Yu, Sheng Zhou, Zhenghai Fan et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0302-x Abstract | Full Text
G9A promotes gastric cancer metastasis by upregulating ITGB3 in a SET domain-independent manner Lei Hu, Ming-de Zang, He-xiao Wang, Bao-gui Zhang, Zhen-qiang Wang et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0322-6 Abstract | Full Text
Rhinovirus 3C protease suppresses apoptosis and triggers caspase-independent cell death Mark Lötzerich, Pascal S. Roulin, Karin Boucke, Robert Witte, Oleg Georgiev et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0306-6 Abstract | Full Text
Intravenous injections of the oncolytic virus M1 as a novel therapy for muscle-invasive bladder cancer Cheng Hu, Ying Liu, Yuan Lin, Jian-Kai Liang, Wen-Wen Zhong et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0325-3 Abstract | Full Text
Glucocorticoids promote apoptosis of proinflammatory monocytes by inhibiting ERK activity Adrian Achuthan, Ahmad S. M. Aslam, Quyen Nguyen, Pui-Yeng Lam, Andrew J. Fleetwood et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0332-4 Abstract | Full Text
Transcriptional repression of DNA repair genes is a hallmark and a cause of cellular senescence   Cell Death & Disease 2018 9: 10.1038/s41419-018-0300-z Abstract | Full Text
Knockout of zebrafish interleukin 7 receptor (IL7R) by the CRISPR/Cas9 system delays retinal neurodevelopment Shijiao Cai, Yang Chen, Yue Shang, Jianlin Cui, Zongjin Li et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0337-z Abstract | Full Text
PEAK1, acting as a tumor promoter in colorectal cancer, is regulated by the EGFR/KRas signaling axis and miR-181d Lanlan Huang, Chuangyu Wen, Xiangling Yang, Qiong Lou, Xiaoyan Wang et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0320-8 Abstract | Full Text
Hemopexin is required for adult neurogenesis in the subventricular zone/olfactory bulb pathway Yanling Zhu, Yang Qiu, Mengjia Chen, Yi Zhang, Li Cao et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0328-0 Abstract | Full Text
Chir99021 and Valproic acid reduce the proliferative advantage of Apc mutant cells Alistair J. Langlands, Thomas D. Carroll, Yu Chen & Inke Näthke Cell Death & Disease 2018 9: 10.1038/s41419-017-0199-9 Abstract | Full Text
Toll-like receptor 4 modulation influences human neural stem cell proliferation and differentiation Chiara Grasselli, Daniela Ferrari, Cristina Zalfa, Matias Soncini, Gianluigi Mazzoccoli et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0139-8 Abstract | Full Text
CFTR mutation enhances Dishevelled degradation and results in impairment of Wnt-dependent hematopoiesis Huaqin Sun, Yan Wang, Jieting Zhang, Yan Chen, Yanyan Liu et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0311-9 Abstract | Full Text
S100A4 promotes lung tumor development through ß-catenin pathway-mediated autophagy inhibition Shasha Hou, Tian Tian, Dianwen Qi, Kaiji Sun, Qi Yuan et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0319-1 Abstract | Full Text
Downregulation of SREBP inhibits tumor growth and initiation by altering cellular metabolism in colon cancer Yang-An Wen, Xiaopeng Xiong, Yekaterina Y. Zaytseva, Dana L. Napier, Emma Vallee et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0330-6 Abstract | Full Text
TR4 nuclear receptor suppresses HCC cell invasion via downregulating the EphA2 expression Ren'an Jin, Hui Lin, Gonghui Li, Junjie Xu, Liang Shi et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0287-5 Abstract | Full Text
Downregulation of PERK activity and eIF2a serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells Jothilatha Krishnamoorthy, Clara Tenkerian, Jyotsana Gupta, Nour Ghaddar, Shuo Wang et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0326-2 Abstract | Full Text
The long non-coding RNA FOXD2-AS1 promotes bladder cancer progression and recurrence through a positive feedback loop with Akt and E2F1 Feng Su, Wang He, Changhao Chen, Mo Liu, Hongwei Liu et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0275-9 Abstract | Full Text
Dural effects of oxidative stress on cardiomyogenesis via Gata4 transcription and protein ubiquitination   Cell Death & Disease 2018 9: 10.1038/s41419-018-0281-y Abstract | Full Text
Lup-20(29)-en-3ß,28-di-yl-nitrooxy acetate affects MCF-7 proliferation through the crosstalk between apoptosis and autophagy in mitochondria Xiaoning Yan, Lei Yang, Gaili Feng, Zhuli Yu, Minjie Xiao et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0255-5 Abstract | Full Text
Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy Valentina Celestini, Tugsan Tezil, Luciana Russo, Candida Fasano, Paola Sanese et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0336-0 Abstract | Full Text
Long non-coding RNA PVT1 predicts poor prognosis and induces radioresistance by regulating DNA repair and cell apoptosis in nasopharyngeal carcinoma Yi He, Yizhou Jing, Fang Wei, Yanyan Tang, Liting Yang et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0265-y Abstract | Full Text
Rage induces hepatocellular carcinoma proliferation and sorafenib resistance by modulating autophagy Jun Li, Peng-Wen Wu, Yuan Zhou, Bo Dai, Peng-Fei Zhang et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0329-z Abstract | Full Text
Interleukin 4 modulates microglia homeostasis and attenuates the early slowly progressive phase of amyotrophic lateral sclerosis Chiara Rossi, Melania Cusimano, Martina Zambito, Annamaria Finardi, Alessia Capotondo et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0288-4 Abstract | Full Text
A novel autophagy inhibitor berbamine blocks SNARE-mediated autophagosome-lysosome fusion through upregulation of BNIP3 Ruoqiu Fu, Qin Deng, Hongwei Zhang, Xiaoye Hu, Yunong Li et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0276-8 Abstract | Full Text
MYCN drives glutaminolysis in neuroblastoma and confers sensitivity to an ROS augmenting agent Tingting Wang, Lingling Liu, Xuyong Chen, Yuqing Shen, Gaojian Lian et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0295-5 Abstract | Full Text
Granzyme B deficiency promotes osteoblastic differentiation and calcification of vascular smooth muscle cells in hypoxic pulmonary hypertension Min Mao, Min Zhang, Anqi Ge, Xin Ge, Rui Gu et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0315-5 Abstract | Full Text
Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification Qingquan Zhang, Ru Huang, Youqiong Ye, Xiaoxia Guo, Jun Lu et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0283-9 Abstract | Full Text
SPRY2 is a novel MET interactor that regulates metastatic potential and differentiation in rhabdomyosarcoma Masum Saini, Aakanksha Verma & Sam J. Mathew Cell Death & Disease 2018 9: 10.1038/s41419-018-0261-2 Abstract | Full Text
Baicalin administration attenuates hyperglycemia-induced malformation of cardiovascular system Guang Wang, Jianxin Liang, Lin-rui Gao, Zhen-peng Si, Xiao-tan Zhang et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0318-2 Abstract | Full Text
The chemokine receptor CCR10 promotes inflammation-driven hepatocarcinogenesis via PI3K/Akt pathway activation Qiong Wu, Jin-xian Chen, Yu Chen, Li-li Cai, Xiao-zhong Wang et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0267-9 Abstract | Full Text
Microfluidic cell sorting by stiffness to examine heterogenic responses of cancer cells to chemotherapy Muhymin Islam, Roman Mezencev, Brynn McFarland, Hannah Brink, Betsy Campbell et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0266-x Abstract | Full Text
Let-7c inhibits cholangiocarcinoma growth but promotes tumor cell invasion and growth at extrahepatic sites Yu Xie, Hang Zhang, Xing-Jun Guo, Ye-Chen Feng, Rui-Zhi He et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0286-6 Abstract | Full Text
Canagliflozin mediated dual inhibition of mitochondrial glutamate dehydrogenase and complex I: an off-target adverse effect Philipp F. Secker, Sascha Beneke, Nadja Schlichenmaier, Johannes Delp, Simon Gutbier et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0273-y Abstract | Full Text
Non-toxic engineered carbon nanodiamond concentrations induce oxidative/nitrosative stress, imbalance of energy metabolism, and mitochondrial dysfunction in microglial and alveolar basal epithelial cells Claudia G. Fresta, Aishik Chakraborty, Manjula B. Wijesinghe, Angela M. Amorini, Giacomo Lazzarino et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0280-z Abstract | Full Text
The cytotoxicity of coxsackievirus B3 is associated with a blockage of autophagic flux mediated by reduced syntaxin 17 expression Lang Tian, Yeyi Yang, Chunyun Li, Jia Chen, Zhuoying Li et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0271-0 Abstract | Full Text
Glycogen synthase kinase-3ß inhibition promotes lysosome-dependent degradation of c-FLIPL in hepatocellular carcinoma Na Zhang, Xiaojia Liu, Lu Liu, Zhesong Deng, Qingxuan Zeng et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0309-3 Abstract | Full Text
BRM270 inhibits cancer stem cell maintenance via microRNA regulation in chemoresistant A549 lung adenocarcinoma cells Taeho Kwon, Nisansala Chandimali, Do Luong Huynh, Jiao Jiao Zhang, Nameun Kim et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0277-7 Abstract | Full Text
Pyruvate kinase M2 regulates photoreceptor structure, function, and viability Ammaji Rajala, Yuhong Wang, Richard S. Brush, Kristine Tsantilas, Connor S. R. Jankowski et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0296-4 Abstract | Full Text
Impaired autophagic flux is associated with the severity of trauma and the role of A2AR in brain cells after traumatic brain injury Xu-Jia Zeng, Ping Li, Ya-Lei Ning, Yan Zhao, Yan Peng et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0316-4 Abstract | Full Text
The oncogene Etv5 promotes MET in somatic reprogramming and orchestrates epiblast/primitive endoderm specification during mESCs differentiation Jinglong Zhang, Hongxia Cao, Jing Xie, Chen Fan, Youlong Xie et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0335-1 Abstract | Full Text
Long noncoding RNA GAS5 promotes bladder cancer cells apoptosis through inhibiting EZH2 transcription Miao Wang, Chen Guo, Liang Wang, Gang Luo, Chao Huang et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0264-z Abstract | Full Text
Loss of NDRG2 in liver microenvironment inhibits cancer liver metastasis by regulating tumor associate macrophages polarization Mengyang Li, Xiaofeng Lai, Ying Zhao, Yuan Zhang, Minghui Li et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0284-8 Abstract | Full Text
Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip Sasan Jalili-Firoozinezhad, Rachelle Prantil-Baun, Amanda Jiang, Ratnakar Potla, Tadanori Mammoto et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0304-8 Abstract | Full Text
STK17B promotes carcinogenesis and metastasis via AKT/GSK-3ß/Snail signaling in hepatocellular carcinoma Yaliang Lan, Jihua Han, Yan Wang, Jiabei Wang, Guangchao Yang et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0262-1 Abstract | Full Text
Lenalidomide regulates CNS autoimmunity by promoting M2 macrophages polarization Qinjie Weng, Jiaying Wang, Jiajia Wang, Jing Wang, Fahmida Sattar et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0290-x Abstract | Full Text
Genetic modification to induce CXCR2 overexpression in mesenchymal stem cells enhances treatment benefits in radiation-induced oral mucositis Zongshan Shen, Jiancheng Wang, Qiting Huang, Yue Shi, Zhewei Wei et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0310-x Abstract | Full Text
Fibroblast growth factor-21 prevents diabetic cardiomyopathy via AMPK-mediated antioxidation and lipid-lowering effects in the heart Hong Yang, Anyun Feng, Sundong Lin, Lechu Yu, Xiufei Lin et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0307-5 Abstract | Full Text
Baicalin induces cellular senescence in human colon cancer cells via upregulation of DEPP and the activation of Ras/Raf/MEK/ERK signaling Zhou Wang, Lingman Ma, Mengqi Su, Yiran Zhou, Ke Mao et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0223-0 Abstract | Full Text
Effect of mitochondrial uncouplers niclosamide ethanolamine (NEN) and oxyclozanide on hepatic metastasis of colon cancer Amer Alasadi, Michael Chen, G. V. T. Swapna, Hanlin Tao, Jingjing Guo et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0092-6 Abstract | Full Text
KRAS induces lung tumorigenesis through microRNAs modulation Lei Shi, Justin Middleton, Young-Jun Jeon, Peter Magee, Dario Veneziano et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0243-9 Abstract | Full Text
Inhibition of KRAS-dependent lung cancer cell growth by deltarasin: blockage of autophagy increases its cytotoxicity Elaine Lai Han Leung, Lian Xiang Luo, Zhong Qiu Liu, Vincent Kam Wai Wong, Lin Lin Lu et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0065-9 Abstract | Full Text
Human umbilical cord mesenchymal stem cell-derived extracellular vesicles promote lung adenocarcinoma growth by transferring miR-410 Liyang Dong, Yanan Pu, Lina Zhang, Qianqian Qi, Lei Xu et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0323-5 Abstract | Full Text
Association of cytosolic sialidase Neu2 with plasma membrane enhances Fas-mediated apoptosis by impairing PI3K-Akt/mTOR-mediated pathway in pancreatic cancer cells Shalini Nath, Chhabinath Mandal, Uttara Chatterjee & Chitra Mandal Cell Death & Disease 2018 9: 10.1038/s41419-017-0191-4 Abstract | Full Text
Autophagy mediates glucose starvation-induced glioblastoma cell quiescence and chemoresistance through coordinating cell metabolism, cell cycle, and survival Lian Wang, Zhouchun Shang, Yang Zhou, Xinyu Hu, Yihong Chen et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0242-x Abstract | Full Text
Dopamine D2 receptor-mediated neuroprotection in a G2019S Lrrk2 genetic model of Parkinson's disease Alessandro Tozzi, Michela Tantucci, Saverio Marchi, Petra Mazzocchetti, Michele Morari et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0221-2 Abstract | Full Text
Glutamine metabolism regulates FLIP expression and sensitivity to TRAIL in triple-negative breast cancer cells Marta Mauro-Lizcano & Abelardo López-Rivas Cell Death & Disease 2018 9: 10.1038/s41419-018-0263-0 Abstract | Full Text
Preconditioning, induced by sub-toxic dose of the neurotoxin L-BMAA, delays ALS progression in mice and prevents Na+/Ca2+ exchanger 3 downregulation Serenella Anzilotti, Paola Brancaccio, Giuseppe Simeone, Valeria Valsecchi, Antonio Vinciguerra et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0227-9 Abstract | Full Text
Glucagon-like peptide-1 receptor regulates endoplasmic reticulum stress-induced apoptosis and the associated inflammatory response in chondrocytes and the progression of osteoarthritis in rat Jian Chen, Jun-Jun Xie, Ke-Si Shi, Yun-Tao Gu, Cong-Cong Wu et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0217-y Abstract | Full Text
Mechanical stretch-induced osteogenic differentiation of human jaw bone marrow mesenchymal stem cells (hJBMMSCs) via inhibition of the NF-?B pathway Xiaoyan Chen, Yuan Liu, Wanghui Ding, Jiejun Shi, Shenglai Li et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0279-5 Abstract | Full Text
MiR-22 suppresses epithelial–mesenchymal transition in bladder cancer by inhibiting Snail and MAPK1/Slug/vimentin feedback loop Mingjie Xu, Jiangfeng Li, Xiao Wang, Shuai Meng, Jiaying Shen et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0206-1 Abstract | Full Text
Ablation of protein phosphatase 5 (PP5) leads to enhanced both bone and cartilage development in mice Jun Wang, Yong Cao, Bin Qiu, Jianyong Du, Tingting Wang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0254-6 Abstract | Full Text
BRD4 regulates cellular senescence in gastric cancer cells via E2F/miR-106b/p21 axis   Cell Death & Disease 2018 9: 10.1038/s41419-017-0181-6 Abstract | Full Text
Actin nucleator Spire 1 is a regulator of ectoplasmic specialization in the testis Qing Wen, Nan Li, Xiang Xiao, Wing-yee Lui, Darren S. Chu et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0201-6 Abstract | Full Text
RIPK1-dependent cell death: a novel target of the Aurora kinase inhibitor Tozasertib (VX-680) Sofie Martens, Vera Goossens, Lars Devisscher, Sam Hofmans, Polien Claeys et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0245-7 Abstract | Full Text
Temozolomide–perillyl alcohol conjugate downregulates O6-methylguanin DNA methltransferase via inducing ubiquitination-dependent proteolysis in non-small cell lung cancer Xingguo Song, Li Xie, Minghui Chang, Xinran Geng, Xingwu Wang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0193-2 Abstract | Full Text
Alterations of specific chromatin conformation affect ATRA-induced leukemia cell differentiation Yanjian Li, Yi He, Zhengyu Liang, Yang Wang, Fengling Chen et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0173-6 Abstract | Full Text
Glycogen synthase protects neurons from cytotoxicity of mutant huntingtin by enhancing the autophagy flux Anupama Rai, Pankaj Kumar Singh, Virender Singh, Vipendra Kumar, Rohit Mishra et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0190-5 Abstract | Full Text
Pharmacological activation of autophagy favors the clearing of intracellular aggregates of misfolded prion protein peptide to prevent neuronal death Stefano Thellung, Beatrice Scoti, Alessandro Corsaro, Valentina Villa, Mario Nizzari et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0252-8 Abstract | Full Text
Regulation of senescence escape by the cdk4–EZH2–AP2M1 pathway in response to chemotherapy Mélanie Le Duff, Julien Gouju, Barbara Jonchère, Jordan Guillon, Bertrand Toutain et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0209-y Abstract | Full Text
bFGF plays a neuroprotective role by suppressing excessive autophagy and apoptosis after transient global cerebral ischemia in rats Dawei Sun, Wenying Wang, Xintao Wang, Yan Wang, Xiaotao Xu et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0229-7 Abstract | Full Text
miR-27b-3p inhibits proliferation and potentially reverses multi-chemoresistance by targeting CBLB/GRB2 in breast cancer cells Danni Chen, Wengong Si, Jiaying Shen, Chengyong Du, Weiyang Lou et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0211-4 Abstract | Full Text
Regenerative potential of tonsil mesenchymal stem cells on surgical cutaneous defect Sung-Chan Shin, Yoojin Seo, Hee Young Park, Da-Woon Jung, Tae-Hoon Shin et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0248-4 Abstract | Full Text
Bone morphogenetic protein 2 promotes human trophoblast cell invasion by upregulating N-cadherin via non-canonical SMAD2/3 signaling Hong-Jin Zhao, Christian Klausen, Yan Li, Hua Zhu, Yan-Ling Wang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0230-1 Abstract | Full Text
Oncogenic HSP60 regulates mitochondrial oxidative phosphorylation to support Erk1/2 activation during pancreatic cancer cell growth Chao Zhou, Hongwei Sun, Chen Zheng, Jing Gao, Qingzi Fu et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0196-z Abstract | Full Text
Homocysteine activates autophagy by inhibition of CFTR expression via interaction between DNA methylation and H3K27me3 in mouse liver Anning Yang, Yun Jiao, Songhao Yang, Mei Deng, Xiaoling Yang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0216-z Abstract | Full Text
Plasma Hemopexin ameliorates murine spinal cord injury by switching microglia from the M1 state to the M2 state Dunxin Han, Zhongwang Yu, Weili Liu, Dou Yin, Yingyan Pu et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0236-8 Abstract | Full Text
LanCL1 protects prostate cancer cells from oxidative stress via suppression of JNK pathway Jianqing Wang, Qianyi Xiao, Xu Chen, Shijun Tong, Jianliang Sun et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0207-0 Abstract | Full Text
Combination therapy with proteasome inhibitors and TLR agonists enhances tumour cell death and IL-1ß production Anthony C Tang, Seyed M Rahavi, Shan-Yu Fung, Henry Y Lu, Hong Yang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0194-1 Abstract | Full Text
Sphingolipid de novo biosynthesis is essential for intestine cell survival and barrier function Zhiqiang Li, Inamul Kabir, Gladys Tietelman, Chongmin Huan, Jianglin Fan et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0214-1 Abstract | Full Text
PDE5 inhibition eliminates cancer stem cells via induction of PKA signaling Saskia Klutzny, Anna Anurin, Barbara Nicke, Joseph L. Regan, Martin Lange et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0202-5 Abstract | Full Text
Downregulation of ß1,4-galactosyltransferase 5 improves insulin resistance by promoting adipocyte commitment and reducing inflammation Shu-Fen Li, Cui-Song Zhu, Yu-Meng Wang, Xin-Xin Xie, Liu-Ling Xiao et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0239-5 Abstract | Full Text
miR-143-3p targeting of ITGA6 suppresses tumour growth and angiogenesis by downregulating PLGF expression via the PI3K/AKT pathway in gallbladder carcinoma Yun-Peng Jin, Yun-Ping Hu, Xiang-Song Wu, Yao-Shi Wu, Yuan-Yuan Ye et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0258-2 Abstract | Full Text
Osteopontin promotes metastasis of intrahepatic cholangiocarcinoma through recruiting MAPK1 and mediating Ser675 phosphorylation of ß-Catenin Yan Zheng, Chuang Zhou, Xin-Xin Yu, Chao Wu, Hu-Liang Jia et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0226-x Abstract | Full Text
Long noncoding RNA PANDAR blocks CDKN1A gene transcription by competitive interaction with p53 protein in gastric cancer Jun Liu, Qiwen Ben, Eryi Lu, Xiangyi He, Xiaoqun Yang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0246-6 Abstract | Full Text
Multiple molecular mechanisms form a positive feedback loop driving amyloid ß42 peptide-induced neurotoxicity via activation of the TRPM2 channel in hippocampal neurons Xin Li & Lin-Hua Jiang Cell Death & Disease 2018 9: 10.1038/s41419-018-0270-1 Abstract | Full Text
LncRNA NCK1-AS1 promotes proliferation and induces cell cycle progression by crosstalk NCK1-AS1/miR-6857/CDK1 pathway   Cell Death & Disease 2018 9: 10.1038/s41419-017-0249-3 Abstract | Full Text
Neuroglobin boosts axon regeneration during ischemic reperfusion via p38 binding and activation depending on oxygen signal Xin Xin Xiong, Feng Pan, Ruo Qiao Chen, Dian Xing Hu, Xin Yao Qiu et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0260-8 Abstract | Full Text
Epigenetic inhibition of Wnt pathway suppresses osteogenic differentiation of BMSCs during osteoporosis Huan Jing, Xiaoxia Su, Bo Gao, Yi Shuai, Ji Chen et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0231-0 Abstract | Full Text
14-3-3? delivered by hepatocellular carcinoma-derived exosomes impaired anti-tumor function of tumor-infiltrating T lymphocytes Xiaochen Wang, Haiyuan Shen, Guangyan Zhangyuan, Ruyi Huang, Wenjie Zhang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0180-7 Abstract | Full Text
Photosensitization of A2E triggers telomere dysfunction and accelerates retinal pigment epithelium senescence Jing Wang, Yiji Feng, Peng Han, Fenghua Wang, Xueting Luo et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0200-7 Abstract | Full Text
UHRF1 depletion sensitizes retinoblastoma cells to chemotherapeutic drugs via downregulation of XRCC4 Heng He, Chunsik Lee & Jong Kyong Kim Cell Death & Disease 2018 9: 10.1038/s41419-017-0203-4 Abstract | Full Text
Fasudil increases temozolomide sensitivity and suppresses temozolomide-resistant glioma growth via inhibiting ROCK2/ABCG2 Xin Zhang, Xiuting Liu, Wei Zhou, Mengdi Yang, Yang Ding et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0251-9 Abstract | Full Text
The binding landscape of a partially-selective isopeptidase inhibitor with potent pro-death activity, based on the bis(arylidene)cyclohexanone scaffold Sonia Ciotti, Riccardo Sgarra, Andrea Sgorbissa, Carlotta Penzo, Andrea Tomasella et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0259-1 Abstract | Full Text
ROS-independent ER stress-mediated NRF2 activation promotes warburg effect to maintain stemness-associated properties of cancer-initiating cells Ching-Wen Chang, Yu-Syuan Chen, Yeou-Guang Tsay, Chia-Li Han, Yu-Ju Chen et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0250-x Abstract | Full Text
PHB2 interacts with LC3 and SQSTM1 is required for bile acids-induced mitophagy in cholestatic liver   Cell Death & Disease 2018 9: 10.1038/s41419-017-0228-8 Abstract | Full Text
Osteoblast-targeted delivery of miR-33-5p attenuates osteopenia development induced by mechanical unloading in mice Han Wang, Zebing Hu, Fei Shi, Jingjing Dong, Lei Dang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0210-5 Abstract | Full Text
The antitumor natural product tanshinone IIA inhibits protein kinase C and acts synergistically with 17-AAG Chao Lv, Hua-Wu Zeng, Jin-Xin Wang, Xing Yuan, Chuang Zhang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0247-5 Abstract | Full Text
Evaluation of autophagy inducers in epithelial cells carrying the ?F508 mutation of the cystic fibrosis transmembrane conductance regulator CFTR Shaoyi Zhang, Gautier Stoll, José Manuel Bravo San Pedro, Valentina Sica, Allan Sauvat et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0235-9 Abstract | Full Text
Genome-wide DNA methylation analysis reveals that mouse chemical iPSCs have closer epigenetic features to mESCs than OSKM-integrated iPSCs Wangfang Ping, Jian Hu, Gongcheng Hu, Yawei Song, Qing Xia et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0234-x Abstract | Full Text
EZH2 inhibits autophagic cell death of aortic vascular smooth muscle cells to affect aortic dissection Rui Li, Xin Yi, Xiang Wei, Bo Huo, Xian Guo et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0213-2 Abstract | Full Text
MicroRNA-27a-5p regulation by promoter methylation and MYC signaling in prostate carcinogenesis Daniela Barros-Silva, Pedro Costa-Pinheiro, Henrique Duarte, Elsa Joana Sousa, Adriane Feijó Evangelista et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0241-y Abstract | Full Text
miR-195 targets cyclin D3 and survivin to modulate the tumorigenesis of non-small cell lung cancer Xiaojie Yu, Yiqiang Zhang, David Cavazos, Xiuye Ma, Zhenze Zhao et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0219-9 Abstract | Full Text
MicroRNA-1253 suppresses cell proliferation and invasion of non-small-cell lung carcinoma by targeting WNT5A Meiyue Liu, Yue Zhang, Jie Zhang, Haifeng Cai, Chao Zhang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0218-x Abstract | Full Text
Antitumor activity of EGFR-specific CAR T cells against non-small-cell lung cancer cells in vitro and in mice He Li, Yao Huang, Du-Qing Jiang, Lian-Zhen Cui, Zhou He et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0238-6 Abstract | Full Text
Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis Xianxian Wu, Haiying Zhang, Wei Qi, Ying Zhang, Jiamin Li et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0257-3 Abstract | Full Text
Role of c-Abl and nephrin in podocyte cytoskeletal remodeling induced by angiotensin II Yiqiong Ma, Qian Yang, Zhentong Zhong, Wei Liang, Lu Zhang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0225-y Abstract | Full Text
circHIPK3 regulates cell proliferation and migration by sponging miR-124 and regulating AQP3 expression in hepatocellular carcinoma Genwen Chen, Yanting Shi, Mengmeng Liu & Jianyong Sun Cell Death & Disease 2018 9: 10.1038/s41419-017-0204-3 Abstract | Full Text
Honokiol induces apoptosis and autophagy via the ROS/ERK1/2 signaling pathway in human osteosarcoma cells in vitro and in vivo Kangmao Huang, Yanyan Chen, Rui Zhang, Yizheng Wu, Yan Ma et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0166-5 Abstract | Full Text
Notch1 is a prognostic factor that is distinctly activated in the classical and proneural subtype of glioblastoma and that promotes glioma cell survival via the NF-?B(p65) pathway Long Hai, Chen Zhang, Tao Li, Xingchen Zhou, Bo Liu et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0119-z Abstract | Full Text
TRIM36, a novel androgen-responsive gene, enhances anti-androgen efficacy against prostate cancer by inhibiting MAPK/ERK signaling pathways Chao Liang, Shangqian Wang, Chao Qin, Meilin Bao, Gong Cheng et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0197-y Abstract | Full Text
Mesenchymal stem cells over-expressing cxcl12 enhance the radioresistance of the small intestine Pengyu Chang, Boyin Zhang, Lihong Shao, Wei Song, Weiyan Shi et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0222-1 Abstract | Full Text
Ubiquitin-specific protease 4 promotes hepatocellular carcinoma progression via cyclophilin A stabilization and deubiquitination Tianyi Li, Bin Yan, Yang Ma, Junyong Weng, Shouwen Yang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0182-5 Abstract | Full Text
Game-changing restraint of Ros-damaged phenylalanine, upon tumor metastasis Geraldine Gueron, Nicolás Anselmino, Paula Chiarella, Emiliano G. Ortiz, Sofia Lage Vickers et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0147-8 Abstract | Full Text
Clinorotation-induced autophagy via HDM2-p53-mTOR pathway enhances cell migration in vascular endothelial cells Cheng-Fei Li, Jia-Xing Sun, Yuan Gao, Fei Shi, Yi-Kai Pan et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0185-2 Abstract | Full Text
SMAD4 feedback regulates the canonical TGF-ß signaling pathway to control granulosa cell apoptosis   Cell Death & Disease 2018 9: 10.1038/s41419-017-0205-2 Abstract | Full Text
The MiR-135b–BMAL1–YY1 loop disturbs pancreatic clockwork to promote tumourigenesis and chemoresistance Weiliang Jiang, Senlin Zhao, Jia Shen, Lihong Guo, Yi Sun et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0233-y Abstract | Full Text
Inactivation of ribosomal protein S27-like confers radiosensitivity via the Mdm2-p53 and Mdm2–MRN–ATM axes   Cell Death & Disease 2018 9: 10.1038/s41419-017-0192-3 Abstract | Full Text
Cooperation between Hsp90 and mortalin/GRP75 in resistance to cell death induced by complement C5b-9   Cell Death & Disease 2018 9: 10.1038/s41419-017-0240-z Abstract | Full Text
Nicotine associated breast cancer in smokers is mediated through high level of EZH2 expression which can be reversed by methyltransferase inhibitor DZNepA Kanchan Kumari, Biswajit Das, Amit Adhya, Sanjib Chaudhary, Shantibhusan Senapati et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0224-z Abstract | Full Text
YAP triggers the Wnt/ß-catenin signalling pathway and promotes enterocyte self-renewal, regeneration and tumorigenesis after DSS-induced injury Feihong Deng, Liang Peng, Zhijun Li, Gao Tan, Erbo Liang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0244-8 Abstract | Full Text
Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe Silvia Pietrobono, Roberta Santini, Sinforosa Gagliardi, Francesca Dapporto, David Colecchia et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0142-0 Abstract | Full Text
IL-6 potentiates BMP-2-induced osteogenesis and adipogenesis via two different BMPR1A-mediated pathways Ru-Lin Huang, Yangbai Sun, Chia-Kang Ho, Kai Liu, Qi-Qun Tang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0126-0 Abstract | Full Text
Upregulation of kinesin family member 4A enhanced cell proliferation via activation of Akt signaling and predicted a poor prognosis in hepatocellular carcinoma Yanlin Huang, Hongbo Wang, Yifan Lian, Xiaojuan Wu, Liang Zhou et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0114-4 Abstract | Full Text
Mixed lineage kinase ZAK promotes epithelial–mesenchymal transition in cancer progression Linna Li, Ning Su, Ting Zhou, Dayong Zheng, Zheng Wang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0161-x Abstract | Full Text
RAP80 is an independent prognosis biomarker for the outcome of patients with esophageal squamous cell carcinoma Qingyuan Yang, Wanrun Lin, Zhiwei Liu, Jiabei Zhu, Nan Huang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0177-2 Abstract | Full Text
Comment		Top
Organellar stress intersects the astrocyte endoplasmic reticulum, mitochondria and nucleolus in HIV associated neurodegeneration Shruthi Nooka & Anuja Ghorpade Cell Death & Disease 2018 9: 10.1038/s41419-018-0341-3 Abstract | Full Text
NDRG2 programs tumor-associated macrophages for tumor support Silvia von Karstedt Cell Death & Disease 2018 9: 10.1038/s41419-018-0268-8 Abstract | Full Text
Heterogeneity and cell fate flux in single human pancreatic islet cells Natasha H. J. Ng & Adrian K. K. Teo Cell Death & Disease 2018 9: 10.1038/s41419-018-0269-7 Abstract | Full Text
Beclin1 circulating levels and accelerated aging markers in COPD Frédéric Schlemmer, Laurent Boyer, Thibaud Soumagne, Audrey Ridoux, Christos Chouaid et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0178-1 Abstract | Full Text
Review Article		Top
Hints on ATGL implications in cancer: beyond bioenergetic clues Rolando Vegliante, Luca Di Leo, Fabio Ciccarone & Maria Rosa Ciriolo Cell Death & Disease 2018 9: 10.1038/s41419-018-0345-z Abstract | Full Text
CAR-T cells: the long and winding road to solid tumors   Cell Death & Disease 2018 9: 10.1038/s41419-018-0278-6 Abstract | Full Text
Long non-coding RNAs in ischemic stroke Mei-Hua Bao, Vivian Szeto, Burton B. Yang, Shu-zhen Zhu, Hong-Shuo Sun et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0282-x Abstract | Full Text
The carnitine system and cancer metabolic plasticity Melone Mariarosa Anna Beatrice, Valentino Anna, Margarucci Sabrina, Galderisi Umberto, Giordano Antonio et al. Cell Death & Disease 2018 9: 10.1038/s41419-018-0313-7 Abstract | Full Text
Targeting deubiquitinase USP28 for cancer therapy Xiaofang Wang, Zhiyi Liu, Li Zhang, Zhaozhi Yang, Xingxing Chen et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0208-z Abstract | Full Text
Meeting Report		Top
Meeting Report: The 8th Barossa Meeting—Cell Signaling in Cancer Medicine in the Barossa Valley, Australia Guillermo A. Gomez, Joanna M. Woodcock, Vinay Tergaonkar & Philip A. Gregory Cell Death & Disease 2018 9: 10.1038/s41419-018-0285-7 Abstract | Full Text
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