TABLE OF CONTENTS
| | | | Volume 18, Issue 1 (January 2018) | | In this issue Reviews Original Articles Consensus Article Also new AOP | | | | | Reviews | Top | | Pharmacogenetic biomarkers of response in Crohn’s disease T M Linares-Pineda, M Cañadas-Garre, A Sánchez-Pozo and M Á Calleja-Hernández Pharmacogenomics J 2018 18: 1-13; advance online publication, June 20, 2017; 10.1038/tpj.2017.27 Abstract | Full Text | | | | Predictive genetic markers in neoadjuvant chemoradiotherapy for locally advanced esophageal cancer: a long way to go. Review of the literature M Gusella, E Pezzolo, Y Modena, C Barile, D Menon, G Crepaldi, F La Russa, A P Fraccon and F Pasini Pharmacogenomics J 2018 18: 14-22; advance online publication, June 13, 2017; 10.1038/tpj.2017.25 Abstract | Full Text | | Original Articles | Top | | Epigenomics alternations and dynamic transcriptional changes in responses to 5-fluorouracil stimulation reveal mechanisms of acquired drug resistance of colorectal cancer cells OPEN Y Shen, M Tong, Q Liang, Y Guo, H Q Sun, W Zheng, L Ao, Z Guo and F She Pharmacogenomics J 2018 18: 23-28; advance online publication, January 3, 2017; 10.1038/tpj.2016.91 Abstract | Full Text | | | | Clinical relevance of EMT and stem-like gene expression in circulating tumor cells of metastatic colorectal cancer patients Y Ning, W Zhang, D L Hanna, D Yang, S Okazaki, M D Berger, Y Miyamoto, M Suenaga, M Schirripa, A El-Khoueiry and H-J Lenz Pharmacogenomics J 2018 18: 29-34; advance online publication, August 9, 2016; 10.1038/tpj.2016.62 Abstract | Full Text | | | | ABC transporter polymorphisms are associated with irinotecan pharmacokinetics and neutropenia M Li, E L Seiser, R M Baldwin, J Ramirez, M J Ratain, F Innocenti and D L Kroetz Pharmacogenomics J 2018 18: 35-42; advance online publication, November 15, 2016; 10.1038/tpj.2016.75 Abstract | Full Text | | | | A genetic variant in Rassf1a predicts outcome in mCRC patients treated with cetuximab plus chemotherapy: results from FIRE-3 and JACCRO 05 and 06 trials A Sebio, S Stintzing, V Heinemann, Y Sunakawa, W Zhang, W Ichikawa, A Tsuji, T Takahashi, A Parek, D Yang, S Cao, Y Ning, S Stremitzer, S Matsusaka, S Okazaki, A Barzi, M D Berger and H-J Lenz Pharmacogenomics J 2018 18: 43-48; advance online publication, October 4, 2016; 10.1038/tpj.2016.69 Abstract | Full Text | | | | Genetic polymorphisms as predictive biomarker of survival in patients with gastrointestinal stromal tumors treated with sunitinib J S L Kloth, M C Verboom, J J Swen, T van der Straaten, S Sleijfer, A K L Reyners, N Steeghs, H Gelderblom, H J Guchelaar and R H J Mathijssen Pharmacogenomics J 2018 18: 49-55; advance online publication, January 24, 2017; 10.1038/tpj.2016.83 Abstract | Full Text | | | | A systems biology approach to investigate the mechanism of action of trabectedin in a model of myelomonocytic leukemia OPEN L Mannarino, L Paracchini, I Craparotta, M Romano, S Marchini, R Gatta, E Erba, L Clivio, C Romualdi, M D’Incalci, L Beltrame and L Pattini Pharmacogenomics J 2018 18: 56-63; advance online publication, December 13, 2016; 10.1038/tpj.2016.76 Abstract | Full Text | | | | Association of CTH variant with sinusoidal obstruction syndrome in children receiving intravenous busulfan and cyclophosphamide before hematopoietic stem cell transplantation OPEN P Huezo-Diaz Curtis, C R S Uppugunduri, J Muthukumaran, M A Rezgui, C Peters, P Bader, M Duval, H Bittencourt, Maja Krajinovic and Marc Ansari on behalf of the Paediatric Disease Working Parties of the European Blood and Marrow Transplant group Pharmacogenomics J 2018 18: 64-69; advance online publication, October 25, 2016; 10.1038/tpj.2016.65 Abstract | Full Text | | | | New polymorphisms associated with response to anti-TNF drugs in patients with moderate-to-severe plaque psoriasis R Prieto-Pérez, G Solano-López, T Cabaleiro, M Román, D Ochoa, M Talegón, O Baniandrés, J L López-Estebaranz, P de la Cueva, E Daudén and F Abad-Santos Pharmacogenomics J 2018 18: 70-75; advance online publication, September 27, 2016; 10.1038/tpj.2016.64 Abstract | Full Text | | | | IL17RA gene variants and anti-TNF response among psoriasis patients A Batalla, E Coto, J Gómez, N Eirís, D González-Fernández, C Gómez-De Castro, E Daudén, M Llamas-Velasco, R Prieto-Perez, F Abad-Santos, G Carretero, F S García, Y B Godoy, L F Cardo, B Alonso, S Iglesias and P Coto-Segura Pharmacogenomics J 2018 18: 76-80; advance online publication, September 27, 2016; 10.1038/tpj.2016.70 Abstract | Full Text | | | | Confirmation of an IRAK3 polymorphism as a genetic marker predicting response to anti-TNF treatment in rheumatoid arthritis J Sode, U Vogel, S Bank, P S Andersen, M L Hetland, H Locht, N H H Heegaard and V Andersen Pharmacogenomics J 2018 18: 81-86; advance online publication, October 4, 2016; 10.1038/tpj.2016.66 Abstract | Full Text | | | | Genetically determined high activity of IL-12 and IL-18 in ulcerative colitis and TLR5 in Crohns disease were associated with non-response to anti-TNF therapy S Bank, P S Andersen, J Burisch, N Pedersen, S Roug, J Galsgaard, S Y Turino, J B Brodersen, S Rashid, B K Rasmussen, S Avlund, T B Olesen, H J Hoffmann, B A Nexø, J Sode, U Vogel and V Andersen Pharmacogenomics J 2018 18: 87-97; advance online publication, January 31, 2017; 10.1038/tpj.2016.84 Abstract | Full Text | | | | Genes differentially expressed by methylprednisolone in vivo in CD4 T lymphocytes from multiple sclerosis patients: potential biomarkers C De Andres, M I García, H Goicoechea, M L Martínez-Ginés, J M García-Domínguez, M L Martín, F Romero-Delgado, A Benguría, M Sanjurjo and L A López-Fernández Pharmacogenomics J 2018 18: 98-105; advance online publication, September 27, 2016; 10.1038/tpj.2016.71 Abstract | Full Text | | | | Genome-wide association study identifies pharmacogenomic loci linked with specific antihypertensive drug treatment and new-onset diabetes S-W Chang, C W McDonough, Y Gong, T A Johnson, T Tsunoda, E R Gamazon, M A Perera, A Takahashi, T Tanaka, M Kubo, C J Pepine, J A Johnson and R M Cooper-DeHoff Pharmacogenomics J 2018 18: 106-112; advance online publication, September 27, 2016; 10.1038/tpj.2016.67 Abstract | Full Text | | | | Cost-effectiveness of cytochrome P450 2C19 *2 genotype-guided selection of clopidogrel or ticagrelor in Chinese patients with acute coronary syndrome Y Wang, B P Yan, D Liew and V W Y Lee Pharmacogenomics J 2018 18: 113-120; advance online publication, January 24, 2017; 10.1038/tpj.2016.94 Abstract | Full Text | | | | Increasing BMI is associated with reduced expression of P-glycoprotein (ABCB1 gene) in the human brain with a stronger association in African Americans than Caucasians OPEN J Vendelbo, R H Olesen, J K Lauridsen, J Rungby, J E Kleinman, T M Hyde and A Larsen Pharmacogenomics J 2018 18: 121-126; advance online publication, November 29, 2016; 10.1038/tpj.2016.74 Abstract | Full Text | | | | Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals: CHARGE Pharmacogenomics Working Group J S Floyd, C M Sitlani, C L Avery, R Noordam, X Li, A V Smith, S M Gogarten, J Li, L Broer, D S Evans, S Trompet, J A Brody, J D Stewart, J D Eicher, A A Seyerle, J Roach, L A Lange, H J Lin, J A Kors, T B Harris, R Li-Gao, N Sattar, S R Cummings, K L Wiggins, M D Napier, T Stürmer, J C Bis, K F Kerr, A G Uitterlinden, K D Taylor, D J Stott, R de Mutsert, L J Launer, E L Busch, R Méndez-Giráldez, N Sotoodehnia, E Z Soliman, Y Li, Q Duan, F R Rosendaal, P E Slagboom, K C Wilhelmsen, A P Reiner, Y-DI Chen, S R Heckbert, R C Kaplan, K M Rice, J W Jukema, A D Johnson, Y Liu, D O Mook-Kanamori, V Gudnason, J G Wilson, J I Rotter, C C Laurie, B M Psaty, E A Whitsel, L A Cupples and B H Stricker Pharmacogenomics J 2018 18: 127-135; advance online publication, December 13, 2016; 10.1038/tpj.2016.90 Abstract | Full Text | | | | Nicotine dependence is associated with functional variation in FMO3, an enzyme that metabolizes nicotine in the brain A M Teitelbaum, S E Murphy, G Akk, T B Baker, A Germann, L B von Weymarn, L J Bierut, A Goate, E D Kharasch and A J Bloom Pharmacogenomics J 2018 18: 136-143; advance online publication, March 14, 2017; 10.1038/tpj.2016.92 Abstract | Full Text | | | | Systems genetics analysis of pharmacogenomics variation during antidepressant treatment M B Madsen, L J A Kogelman, H N Kadarmideen and H B Rasmussen Pharmacogenomics J 2018 18: 144-152; advance online publication, October 18, 2016; 10.1038/tpj.2016.68 Abstract | Full Text | | | | An integrated pharmacokinetic/pharmacogenomic analysis of ABCB1 and SLCO1B1 polymorphisms on edoxaban exposure OPEN A G Vandell, J Lee, M Shi, I Rubets, K S Brown and J R Walker Pharmacogenomics J 2018 18: 153-159; advance online publication, November 29, 2016; 10.1038/tpj.2016.82 Abstract | Full Text | | | | The glutathione transferase Mu null genotype leads to lower 6-MMPR levels in patients treated with azathioprine but not with mercaptopurine M M T J Broekman, D R Wong, G J A Wanten, H M Roelofs, C J van Marrewijk, O H Klungel, A L M Verbeek, P M Hooymans, H-J Guchelaar, H Scheffer, L J J Derijks, M J H Coenen and D J de Jong in collaboration with TOPIC Recruitment Team Pharmacogenomics J 2018 18: 160-166; advance online publication, January 3, 2017; 10.1038/tpj.2016.87 Abstract | Full Text | | | | Influence of IL6R gene polymorphisms in the effectiveness to treatment with tocilizumab in rheumatoid arthritis M Maldonado-Montoro, M Cañadas-Garre, A González-Utrilla and M Ángel Calleja-Hernández Pharmacogenomics J 2018 18: 167-172; advance online publication, December 13, 2016; 10.1038/tpj.2016.88 Abstract | Full Text | | | | A polymorphism in the OPRM1 3′-untranslated region is associated with methadone efficacy in treating opioid dependence R C Crist, G A Doyle, E C Nelson, L Degenhardt, N G Martin, G W Montgomery, A J Saxon, W Ling and W H Berrettini Pharmacogenomics J 2018 18: 173-179; advance online publication, December 13, 2016; 10.1038/tpj.2016.89 Abstract | Full Text | | | | Weight of ABCB1 and POR genes on oral tacrolimus exposure in CYP3A5 nonexpressor pediatric patients with stable kidney transplant G N Almeida-Paulo, I Dapía García, R Lubomirov, A M Borobia, N L Alonso-Sánchez, L Espinosa and A J Carcas-Sansuán Pharmacogenomics J 2018 18: 180-186; advance online publication, January 17, 2017; 10.1038/tpj.2016.93 Abstract | Full Text | | | | The global spectrum of protein-coding pharmacogenomic diversity OPEN G E B Wright, B Carleton, M R Hayden and C J D Ross Pharmacogenomics J 2018 18: 187-195; advance online publication, October 25, 2016; 10.1038/tpj.2016.77 Abstract | Full Text | | Consensus Article | Top | | Association between DRD2 and DRD3 gene polymorphisms and gastrointestinal symptoms induced by levodopa therapy in Parkinson’s disease M Rieck, A F Schumacher-Schuh, V Altmann, S M Callegari-Jacques, C R M Rieder and M H Hutz Pharmacogenomics J 2018 18: 196-200; advance online publication, October 25, 2016; 10.1038/tpj.2016.79 Abstract | Full Text | | | | | | | | | | | | Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here. Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. For event advertising opportunities across the Nature Publishing Group portfolio please contact natureevents@nature.com | | | | | | | | Please note that you need to be a subscriber or site-licence holder to enjoy full-text access to The Pharmacogenomics Journal. In order to do so, please purchase a subscription. You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/nams/svc/myaccount (You will need to log in to be recognised as a nature.com registrant). For further technical assistance, please contact our registration department. For print subscription enquiries, please contact our subscription department. 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