Nature Reviews Neuroscience contents March 2018 Volume 19 Number 3 pp 119-180

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TABLE OF CONTENTS
March 2018 Volume 19 Number 3		Advertisement
2016 2-year Impact Factor 28.880 Journal Metrics 2-year Median 23	In this issue Research Highlights Reviews   Also this month Article series: Food intake, metabolism and the brain  Featured article: Imaging structural and functional brain development in early childhood John H. Gilmore, Rebecca C. Knickmeyer & Wei Gao	An open access journal dedicated to highlighting the most important scientific advances in Parkinson's disease research, spanning the motor and non-motor disorders of Parkinson's disease. Part of the Nature Partner Journals series, npj Parkinson's Disease is published in partnership with the Parkinson's Foundation.   Open for submissions >>>
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RESEARCH HIGHLIGHTS   Top Behavioural neuroscience: In hunt mode p119 | doi:10.1038/nrn.2018.18 Two studies characterize inputs to the periaqueductal grey that regulate hunting behaviour in mice. PDF Neural development: 'Enhancing' human cognition p120 | doi:10.1038/nrn.2018.11 Human-gained enhancers (regulatory elements in the human genome that are more active in the human lineage) are shown to regulate progenitor proliferation in the outer subventricular zone, an area that is substantially larger in humans compared with other primates. PDF Cell biology of the neuron: ARC goes viral p120 | doi:10.1038/nrn.2018.9 Two recent papers reveal that the activity-regulated cytoskeleton-associated proteins ARC and Drosophila melanogaster dArc1 auto-assemble into mRNA-containing, virus-like capsids that are released by neurons in exosomal vesicles and that can be endocytosed at the postsynaptic compartment. PDF Neural repair: Tagging mRNA drives regeneration p121 | doi:10.1038/nrn.2018.14 A dynamic mRNA modification promotes axon regeneration in injured peripheral sensory neurons. PDF Spatial processing: An 'other' kind of place cell p122 | doi:10.1038/nrn.2018.12 'Social place cells' of the dorsal hippocampal CA1 region in bats and in rats encode the position of an observed conspecific. PDF Neuroimmunology: Dietary salt-induced deficits p122 | doi:10.1038/nrn.2018.15 In mice, consumption of a high-salt diet induces accumulation of T helper 17 lymphocytes in the gut, leading to a rise in plasma interleukin-17 levels as well as neurovascular dysfunction and cognitive deficits. PDF   Nature Reviews Neuroscience JOBS of the week Professor and Head of the School of Physiology, Pharmacology and Neuroscience University of Bristol Neuroscience Postdoctoral Programme Link�ping University (LiU) Postdoctoral Research Fellow- Computational Nueroscience National Institutes of Health, National Institute on Drug Abuse IRP SRH - Post-Doctoral Research Fellow Spaulding Rehabilitation Hospital Early Clinical Development Director Servier Group More Science jobs from Nature Reviews Neuroscience EVENT 22nd Biennial Meeting of the International Society for Developmental Neuroscience (ISDN2018) 22.05.18 Nara, Japan More science events from
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REVIEWS		Top
Imaging structural and functional brain development in early childhood John H. Gilmore, Rebecca C. Knickmeyer & Wei Gao p123 | doi:10.1038/nrn.2018.1 The human brain undergoes rapid development during the first 2 years of life. Here, Gilmore and colleagues give an overview of recent neuroimaging studies of the developmental trajectories of brain structure and function in the first years after birth. Abstract | Full Text | PDF
Microglia in neuropathic pain: cellular and molecular mechanisms and therapeutic potential Kazuhide Inoue & Makoto Tsuda p138 | doi:10.1038/nrn.2018.2 The changes in spinal cord excitability proposed to drive neuropathic pain have been linked to alterations in microglial function. Inoue and Tsuda describe our current understanding of the molecular mechanisms involved and consider implications for therapeutic approaches to chronic pain. Abstract | Full Text | PDF
Article series: Food intake, metabolism and the brain Leptin and brain–adipose crosstalks Alexandre Caron, Syann Lee, Joel K. Elmquist & Laurent Gautron p153 | doi:10.1038/nrn.2018.7 The brain regulates adipose tissue metabolism through sympathetic efferent pathways; in turn, adipose tissues relay energy-status information to the brain. This Review gives an overview of interactions between the brain and adipose tissues, with a particular focus on leptin as a regulator of these communications. Abstract | Full Text | PDF
Control of synaptic plasticity in deep cortical networks Pieter R. Roelfsema & Anthony Holtmaat p166 | doi:10.1038/nrn.2018.6 How are synapses optimally strengthened or weakened to improve network performance? Roelfsema and Holtmaat provide an overview of factors that influence synaptic plasticity, particularly in deep, multilayered biological networks, and present a specific framework in which neuromodulators and feedback connections may interact to selectively potentiate synapses responsible for rewarded action. Abstract | Full Text | PDF
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