Cell Death and Disease - Table of Contents alert Volume 9, January 2018

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TABLE OF CONTENTS Volume 9 (January 2018) In this issue Editorial Original Article Article Comment Correspondence Review Article   Sign up for e-alerts Web feed Editorial   Cell death-based treatment of various diseases: a fifty-year journey Vitaliy O. Kaminskyy & Boris Zhivotovsky Cell Death & Disease 2018 9: 10.1038/s41419-017-0168-3 Abstract | Full Text Cell-in-cell phenomena, cannibalism, and autophagy: is there a relationship? Stefano Fais & Michael Overholtzer Cell Death & Disease 2018 9: 10.1038/s41419-017-0111-7 Abstract | Full Text Original Article   Influence of c-Src on hypoxic resistance to paclitaxel in human ovarian cancer cells and reversal of FV-429 Qinglong Guo, Lu Lu, Yan Liao, Xiaoping Wang, Yi Zhang et al. Cell Death & Disease 2018 9: 10.1038/cddis.2017.367 Abstract | Full Text Article   Ubiquitin C decrement plays a pivotal role in replicative senescence of bone marrow mesenchymal stromal cells Jiyeon Kim, Yonggoo Kim, Hayoung Choi, Ahlm Kwon, Dong Wook Jekarl et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0032-5 Abstract | Full Text Human papillomavirus E7 induces p63 expression to modulate DNA damage response Sahar Eldakhakhny, Qing Zhou, Emma J. Crosbie & Berna S. Sayan Cell Death & Disease 2018 9: 10.1038/s41419-017-0149-6 Abstract | Full Text microRNA-874 suppresses tumor proliferation and metastasis in hepatocellular carcinoma by targeting the DOR/EGFR/ERK pathway Yi Zhang, Yangchao Wei, Xuan Li, Xingsi Liang, Liming Wang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0131-3 Abstract | Full Text Neutralization of CD95 ligand protects the liver against ischemia-reperfusion injury and prevents acute liver failure Mohammed Al-Saeedi, Niels Steinebrunner, Hassan Kudsi, Niels Halama, Carolin Mogler et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0150-0 Abstract | Full Text Downregulation of annexin A3 inhibits tumor metastasis and decreases drug resistance in breast cancer Ruikai Du, Bingjie Liu, Lei Zhou, Dong Wang, Xueyan He et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0143-z Abstract | Full Text Synergistic effect of a novel autophagy inhibitor and Quizartinib enhances cancer cell death Amanda Tomie Ouchida, Yingbo Li, Jiefei Geng, Ayaz Najafov, Dimitry Ofengeim et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0170-9 Abstract | Full Text iPSC modeling of severe aplastic anemia reveals impaired differentiation and telomere shortening in blood progenitors Dario Melguizo-Sanchis, Yaobo Xu, Dheraj Taheem, Min Yu, Katarzyna Tilgner et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0141-1 Abstract | Full Text Dual PI3K/mTOR inhibitor BEZ235 as a promising therapeutic strategy against paclitaxel-resistant gastric cancer via targeting PI3K/Akt/mTOR pathway Dongshao Chen, Xiaoting Lin, Cheng Zhang, Zhentao Liu, Zuhua Chen et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0132-2 Abstract | Full Text Downregulation of MCL-1 and upregulation of PUMA using mTOR inhibitors enhance antitumor efficacy of BH3 mimetics in triple-negative breast cancer   Cell Death & Disease 2018 9: 10.1038/s41419-017-0169-2 Abstract | Full Text Targeting EHMT2 reverses EGFR-TKI resistance in NSCLC by epigenetically regulating the PTEN/AKT signaling pathway Lihui Wang, Xiaoyu Dong, Yong Ren, Juanjuan Luo, Pei Liu et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0120-6 Abstract | Full Text Involvement of both caspase-8 and Noxa-activated pathways in endoplasmic reticulum stress-induced apoptosis in triple-negative breast tumor cells   Cell Death & Disease 2018 9: 10.1038/s41419-017-0164-7 Abstract | Full Text SIRT1 induces epithelial-mesenchymal transition by promoting autophagic degradation of E-cadherin in melanoma cells   Cell Death & Disease 2018 9: 10.1038/s41419-017-0167-4 Abstract | Full Text FLI1 and PKC co-activation promote highly efficient differentiation of human embryonic stem cells into endothelial-like cells Hao Zhao, Yan Zhao, Zili Li, Qi Ouyang, Yi Sun et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0162-9 Abstract | Full Text Primed atypical ductal hyperplasia-associated fibroblasts promote cell growth and polarity changes of transformed epithelium-like breast cancer MCF-7 cells via miR-200b/c-IKKβ signaling Yan Sun, Dan Yang, Lei Xi, Yanlin Chen, Lixin Fu et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0133-1 Abstract | Full Text The responsively decreased PKM2 facilitates the survival of pancreatic cancer cells in hypoglucose Xiang Li, Shichang Deng, Mingliang Liu, Yan Jin, Shuai Zhu et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0158-5 Abstract | Full Text The BAX/BAK-like protein BOK is a prognostic marker in colorectal cancer Steven Carberry, Beatrice D’Orsi, Naser Monsefi, Manuela Salvucci, Orna Bacon et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0140-2 Abstract | Full Text c-FLIP is a target of the E3 ligase deltex1 in gastric cancer Tzu-Sheng Hsu, Shu-Ting Mo, Ping-Ning Hsu & Ming-Zong Lai Cell Death & Disease 2018 9: 10.1038/s41419-017-0165-6 Abstract | Full Text Cell death-based treatment of lung adenocarcinoma Tatiana V. Denisenko, Inna N. Budkevich & Boris Zhivotovsky Cell Death & Disease 2018 9: 10.1038/s41419-017-0063-y Abstract | Full Text Defining the role of the tumor vasculature in antitumor immunity and immunotherapy Marco B. Schaaf, Abhishek D. Garg & Patrizia Agostinis Cell Death & Disease 2018 9: 10.1038/s41419-017-0061-0 Abstract | Full Text MIF inhibits the formation and toxicity of misfolded SOD1 amyloid aggregates: implications for familial ALS Neta Shvil, Victor Banerjee, Guy Zoltsman, Tom Shani, Joy Kahn et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0130-4 Abstract | Full Text Givinostat reduces adverse cardiac remodeling through regulating fibroblasts activation Marika Milan, Valentina Pace, Fabio Maiullari, Maila Chirivì, Denisa Baci et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0174-5 Abstract | Full Text Cell death-based treatment of childhood cancer Mike-Andrew Westhoff, Nicolas Marschall, Michael Grunert, Georg Karpel-Massler, Stefan Burdach et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0062-z Abstract | Full Text Non-alcoholic fatty liver disease phenotypes in patients with inflammatory bowel disease Alessandro Sartini, Stefano Gitto, Marcello Bianchini, Maria Chiara Verga, Maria Di Girolamo et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0124-2 Abstract | Full Text Induced neural stem cell-derived astrocytes modulate complement activation and mediate neuroprotection following closed head injury Mou Gao, Qin Dong, Yingzhou Lu, Hui Yao, Mingming Zou et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0172-7 Abstract | Full Text Identification of microRNA signature in the progression of gestational trophoblastic disease Jiu-Ru Zhao, Wei-Wei Cheng, Ya-Xin Wang, Mei Cai, Wei-Bin Wu et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0108-2 Abstract | Full Text Differential effects of reticulophagy and mitophagy on nonalcoholic fatty liver disease Lijun Pang, Kai Liu, Daojie Liu, Fudong Lv, Yunjin Zang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0136-y Abstract | Full Text Honokiol is a FOXM1 antagonist Marianna Halasi, Ben Hitchinson, Binal N. Shah, Renáta Váraljai, Irum Khan et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0156-7 Abstract | Full Text HMG-box transcription factor 1: a positive regulator of the G1/S transition through the Cyclin-CDK-CDKI molecular network in nasopharyngeal carcinoma Shiwei He, Sheng Yang, Man Niu, Yancheng Zhong, Dan Gao et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0175-4 Abstract | Full Text MicroRNA-379-5p is associate with biochemical premature ovarian insufficiency through PARP1 and XRCC6 Yujie Dang, Xiaoyan Wang, Yajing Hao, Xinyue Zhang, Shidou Zhao et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0163-8 Abstract | Full Text miR-375 is involved in Hippo pathway by targeting YAP1/TEAD4-CTGF axis in gastric carcinogenesis Wei Kang, Tingting Huang, Yuhang Zhou, Jinglin Zhang, Raymond W. M. Lung et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0134-0 Abstract | Full Text The cytomegalovirus protein US31 induces inflammation through mono-macrophages in systemic lupus erythematosus by promoting NF-κB2 activation Gangqiang Guo, Sisi Ye, Shangdan Xie, Lele Ye, Cong Lin et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0122-4 Abstract | Full Text Elimination of stem-like cancer cell side-population by auranofin through modulation of ROS and glycolysis Guo-Xin Hou, Pan-Pan Liu, Shengyi Zhang, Mengqi Yang, Jianwei Liao et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0159-4 Abstract | Full Text Optineurin-mediated mitophagy protects renal tubular epithelial cells against accelerated senescence in diabetic nephropathy Kehong Chen, Huanzi Dai, Junjie Yuan, Jia Chen, Lirong Lin et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0127-z Abstract | Full Text Long non-coding RNA HOTTIP promotes BCL-2 expression and induces chemoresistance in small cell lung cancer by sponging miR-216a Yanqin Sun, Bingshuang Hu, Qiongyao Wang, Minting Ye, Qianqian Qiu et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0113-5 Abstract | Full Text Covalent ISG15 conjugation to CHIP promotes its ubiquitin E3 ligase activity and inhibits lung cancer cell growth in response to type I interferon Lang Yoo, A-Rum Yoon, Chae-Ok Yun & Kwang Chul Chung Cell Death & Disease 2018 9: 10.1038/s41419-017-0138-9 Abstract | Full Text The inhibition of UBC13 expression and blockage of the DNMT1-CHFR-Aurora A pathway contribute to paclitaxel resistance in ovarian cancer Xu Zhang, Yan Feng, Xin-Yu Wang, Ya-Nan Zhang, Chun-Nv Yuan et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0137-x Abstract | Full Text CD40L mediated alternative NFκB-signaling induces resistance to BCR-inhibitors in patients with mantle cell lymphoma Hilka Rauert-Wunderlich, Martina Rudelius, Ingolf Berberich & Andreas Rosenwald Cell Death & Disease 2018 9: 10.1038/s41419-017-0157-6 Abstract | Full Text Multifunctional viral protein γ34.5 manipulates nucleolar protein NOP53 for optimal viral replication of HSV-1   Cell Death & Disease 2018 9: 10.1038/s41419-017-0116-2 Abstract | Full Text Rosmarinic acid attenuates cardiac fibrosis following long-term pressure overload via AMPKα/Smad3 signaling Xin Zhang, Zhen-Guo Ma, Yu-Pei Yuan, Si-Chi Xu, Wen-Ying Wei et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0123-3 Abstract | Full Text Prolactin inhibits the progression of intervertebral disc degeneration through inactivation of the NF-κB pathway in rats Xiexing Wu, Yu Liu, Xiaobin Guo, Wei Zhou, Liangliang Wang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0151-z Abstract | Full Text Transmembrane protein 170B is a novel breast tumorigenesis suppressor gene that inhibits the Wnt/β-catenin pathway Mengwei Li, Yanzhen Han, Haoze Zhou, Xin Li, Chenyu Lin et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0128-y Abstract | Full Text Long non-coding RNA and microRNA-675/let-7a mediates the protective effect of melatonin against early brain injury after subarachnoid hemorrhage via targeting TP53 and neural growth factor Song Yang, Wanzhong Tang, Yuchao He, Linbao Wen, Bin Sun et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0155-8 Abstract | Full Text Dysfunctional autophagy following exposure to pro-inflammatory cytokines contributes to pancreatic β-cell apoptosis Martine Lambelet, Leticia F. Terra, Makiko Fukaya, Kira Meyerovich, Leticia Labriola et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0121-5 Abstract | Full Text Overexpression of parkin protects retinal ganglion cells in experimental glaucoma Yi Dai, Xinxin Hu & Xinghuai Sun Cell Death & Disease 2018 9: 10.1038/s41419-017-0146-9 Abstract | Full Text Dual roles of miR-374a by modulated c-Jun respectively targets CCND1-inducing PI3K/AKT signal and PTEN-suppressing Wnt/β-catenin signaling in non-small-cell lung cancer Mengyang Zhao, Ping Xu, Zhen Liu, Yan Zhen, Yiyu Chen et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0103-7 Abstract | Full Text Inhibition of p53 prevents diabetic cardiomyopathy by preventing early-stage apoptosis and cell senescence, reduced glycolysis, and impaired angiogenesis Junlian Gu, Shudong Wang, Hua Guo, Yi Tan, Yaqin Liang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0093-5 Abstract | Full Text MicroRNA miR-4779 suppresses tumor growth by inducing apoptosis and cell cycle arrest through direct targeting of PAK2 and CCND3 Kyung Hee Koo & Heechung Kwon Cell Death & Disease 2018 9: 10.1038/s41419-017-0100-x Abstract | Full Text A caspase-2-RFXANK interaction and its implication for MHC class II expression Jeremy Forsberg, Xinge Li, Birce Akpinar, Roger Salvatori, Martin Ott et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0144-y Abstract | Full Text A novel ruthenium complex with xanthoxylin induces S-phase arrest and causes ERK1/2-mediated apoptosis in HepG2 cells through a p53-independent pathway Nanashara C. de Carvalho, Sara P. Neves, Rosane B. Dias, Ludmila de F. Valverde, Caroline B. S. Sales et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0104-6 Abstract | Full Text Nrf2 antioxidant pathway suppresses Numb-mediated epithelial–mesenchymal transition during pulmonary fibrosis Zhihui Zhang, Jiao Qu, Cheng Zheng, Panpan Zhang, Wencheng Zhou et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0198-x Abstract | Full Text Arsenic trioxide promoting ETosis in acute promyelocytic leukemia through mTOR-regulated autophagy Tao Li, Ruishuang Ma, Yan Zhang, Hongdan Mo, Xiaoyan Yang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0018-3 Abstract | Full Text Mitochondria are transported along microtubules in membrane nanotubes to rescue distressed cardiomyocytes from apoptosis Jing Shen, Jiang-Hui Zhang, Han Xiao, Ji-Min Wu, Kang-Min He et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0145-x Abstract | Full Text Transcriptional regulation of P63 on the apoptosis of male germ cells and three stages of spermatogenesis in mice Hong Wang, Qingqing Yuan, Minghui Niu, Wenhui Zhang, Liping Wen et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0046-z Abstract | Full Text TACC3 transcriptionally upregulates E2F1 to promote cell growth and confer sensitivity to cisplatin in bladder cancer   Cell Death & Disease 2018 9: 10.1038/s41419-017-0112-6 Abstract | Full Text BIM and NOXA are mitochondrial effectors of TAF6δ-driven apoptosis Aurélie Delannoy, Emmanuelle Wilhelm, Sebastian Eilebrecht, Edith Milena Alvarado-Cuevas, Arndt G Benecke et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0115-3 Abstract | Full Text Dihydropyrimidine dehydrogenase predicts survival and response to interferon-α in hepatocellular carcinoma Wei-Ping Zhu, Ze-Yang Liu, Yi-Ming Zhao, Xi-Gan He, Qi Pan et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0098-0 Abstract | Full Text Pathological hydrogen peroxide triggers the fibrillization of wild-type SOD1 via sulfenic acid modification of Cys-111 Wen-Chang Xu, Jin-Zhao Liang, Cheng Li, Zhi-Xin He, Han-Ye Yuan et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0106-4 Abstract | Full Text Impairment of Fas-ligand–caveolin-1 interaction inhibits Fas-ligand translocation to rafts and Fas-ligand-induced cell death   Cell Death & Disease 2018 9: 10.1038/s41419-017-0109-1 Abstract | Full Text PLZF inhibits proliferation and metastasis of gallbladder cancer by regulating IFIT2 Hui Shen, Ming Zhan, Yonglong Zhang, Shuai Huang, Sunwang Xu et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0107-3 Abstract | Full Text Anthelmintic niclosamide suppresses transcription of BCR-ABL fusion oncogene via disabling Sp1 and induces apoptosis in imatinib-resistant CML cells harboring T315I mutant Bei Jin, Chengyan Wang, Yingying Shen & Jingxuan Pan Cell Death & Disease 2018 9: 10.1038/s41419-017-0075-7 Abstract | Full Text SOCE induced calcium overload regulates autophagy in acute pancreatitis via calcineurin activation   Cell Death & Disease 2018 9: 10.1038/s41419-017-0073-9 Abstract | Full Text Insight into the role of PIKK family members and NF-кB in DNAdamage-induced senescence and senescence-associated secretory phenotype of colon cancer cells   Cell Death & Disease 2018 9: 10.1038/s41419-017-0069-5 Abstract | Full Text Polo-like kinase 4 mediates epithelial–mesenchymal transition in neuroblastoma via PI3K/Akt signaling pathway Xiangdong Tian, Dejun Zhou, Lu Chen, Yao Tian, Benfu Zhong et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0088-2 Abstract | Full Text Melatonin inhibits apoptotic cell death induced by Vibrio vulnificus VvhA via melatonin receptor 2 coupling with NCF-1 Sei-Jung Lee, Hyun Jik Lee, Young Hyun Jung, Jun Sung Kim, Sang Ho Choi et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0083-7 Abstract | Full Text Hepatic SMARCA4 predicts HCC recurrence and promotes tumour cell proliferation by regulating SMAD6 expression Zhiao Chen, Xinyuan Lu, Deshui Jia, Ying Jing, Di Chen et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0090-8 Abstract | Full Text Nucleolin and ErbB2 inhibition reduces tumorigenicity of ErbB2-positive breast cancer   Cell Death & Disease 2018 9: 10.1038/s41419-017-0067-7 Abstract | Full Text Epstein-Barr virus encoded latent membrane protein 1 suppresses necroptosis through targeting RIPK1/3 ubiquitination Xiaolan Liu, Yueshuo Li, Songling Peng, Xinfang Yu, Wei Li et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0081-9 Abstract | Full Text Mitochondrial glutamine metabolism via GOT2 supports pancreatic cancer growth through senescence inhibition Seungyeon Yang, Sunsook Hwang, Minjoong Kim, Sung Bin Seo, Jeong-Hwa Lee et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0089-1 Abstract | Full Text miR-663 sustains NSCLC by inhibiting mitochondrial outer membrane permeabilization (MOMP) through PUMA/BBC3 and BTG2   Cell Death & Disease 2018 9: 10.1038/s41419-017-0080-x Abstract | Full Text PI3K/mTOR inhibition promotes the regression of experimental vascular malformations driven by PIK3CA-activating mutations Laura di Blasio, Alberto Puliafito, Paolo Armando Gagliardi, Valentina Comunanza, Desiana Somale et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0064-x Abstract | Full Text Ethanol sensitizes hepatocytes for TGF-β-triggered apoptosis Haristi Gaitantzi, Christoph Meyer, Pia Rakoczy, Maria Thomas, Kristin Wahl et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0071-y Abstract | Full Text 2,5-Hexanedione induces dopaminergic neurodegeneration through integrin αMβ2/NADPH oxidase axis-mediated microglial activation Cong Zhang, Liyan Hou, Jie Yang, Yuning Che, Fuqiang Sun et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0091-7 Abstract | Full Text ZEB1 confers chemotherapeutic resistance to breast cancer by activating ATM Xiang Zhang, Zhen Zhang, Qing Zhang, Quansheng Zhang, Peiqing Sun et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0087-3 Abstract | Full Text U-box ubiquitin ligase PPIL2 suppresses breast cancer invasion and metastasis by altering cell morphology and promoting SNAI1 ubiquitination and degradation Zhaojun Jia, Miao Wang, Shujing Li, Xiahui Li, Xiao-Yan Bai et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0094-4 Abstract | Full Text Glycolysis promotes caspase-3 activation in lipid rafts in T cells Michael A. Secinaro, Karen A. Fortner, Oliver Dienz, Angela Logan, Michael P. Murphy et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0099-z Abstract | Full Text Autophagy promotes MSC-mediated vascularization in cutaneous wound healing via regulation of VEGF secretion Y. An, W. J. Liu, P. Xue, Y. Ma, L. Q. Zhang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0082-8 Abstract | Full Text The silent healer: miR-205-5p up-regulation inhibits epithelial to mesenchymal transition in colon cancer cells by indirectly up-regulating E-cadherin expression Diana Gulei, Lorand Magdo, Ancuta Jurj, Lajos Raduly, Roxana Cojocneanu-Petric et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0102-8 Abstract | Full Text Systems modeling accurately predicts responses to genotoxic agents and their synergism with BCL-2 inhibitors in triple negative breast cancer cells   Cell Death & Disease 2018 9: 10.1038/s41419-017-0039-y Abstract | Full Text HBV infection potentiates resistance to S-phase arrest-inducing chemotherapeutics by inhibiting CHK2 pathway in diffuse large B-cell lymphoma Xinying Zhao, Xudong Guo, Libo Xing, Wenqin Yue, Haisen Yin et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0097-1 Abstract | Full Text FBXL10 contributes to the development of diffuse large B-cell lymphoma by epigenetically enhancing ERK1/2 signaling pathway Xiujuan Zhao, Xing Wang, Qian Li, Wanbiao Chen, Na Zhang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0066-8 Abstract | Full Text Sirt6 overexpression suppresses senescence and apoptosis of nucleus pulposus cells by inducing autophagy in a model of intervertebral disc degeneration Jian Chen, Jun-Jun Xie, Meng-Yun Jin, Yun-Tao Gu, Cong-Cong Wu et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0085-5 Abstract | Full Text PCDHGA9 acts as a tumor suppressor to induce tumor cell apoptosis and autophagy and inhibit the EMT process in human gastric cancer Junyong Weng, Jingbo Xiao, Yushuai Mi, Xu Fang, Yahuang Sun et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0189-y Abstract | Full Text Dual suppression of inner and outer mitochondrial membrane functions augments apoptotic responses to oncogenic MAPK inhibition Madhavika N. Serasinghe, Jesse D. Gelles, Kent Li, Lauren Zhao, Franco Abbate et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0044-1 Abstract | Full Text EGFR activation triggers cellular hypertrophy and lysosomal disease in NAGLU-depleted cardiomyoblasts, mimicking the hallmarks of mucopolysaccharidosis IIIB Valeria De Pasquale, Antonio Pezone, Patrizia Sarogni, Alfonso Tramontano, Gabriele Giacomo Schiattarella et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0187-0 Abstract | Full Text Expression of inflammasome proteins and inflammasome activation occurs in human, but not in murine keratinocytes Jennifer Sand, Eric Haertel, Thomas Biedermann, Emmanuel Contassot, Ernst Reichmann et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0009-4 Abstract | Full Text AMP-activated protein kinase agonist N6-(3-hydroxyphenyl)adenosine protects against fulminant hepatitis by suppressing inflammation and apoptosis Jin Li, Bo Chen, Liping Zhong, Feng Gao, Haibo Zhu et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0118-0 Abstract | Full Text Discovery of a small-molecule protein kinase Cδ-selective activator with promising application in colon cancer therapy Cláudia Bessa, Joana Soares, Liliana Raimundo, Joana B. Loureiro, Célia Gomes et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0154-9 Abstract | Full Text Phosphorylation of ULK1 by AMPK is essential for mouse embryonic stem cell self-renewal and pluripotency Jiaqi Gong, Haifeng Gu, Lin Zhao, Liang Wang, Pinglei Liu et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0054-z Abstract | Full Text Sensitizing tumor cells to conventional drugs: HSP70 chaperone inhibitors, their selection and application in cancer models Vladimir F. Lazarev, Dmitry V. Sverchinsky, Elena R. Mikhaylova, Pavel I. Semenyuk, Elena Y. Komarova et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0160-y Abstract | Full Text FEZF1-AS1/miR-107/ZNF312B axis facilitates progression and Warburg effect in pancreatic ductal adenocarcinoma Huilin Ye, Quanbo Zhou, Shangyou Zheng, Guolin Li, Qing Lin et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0052-1 Abstract | Full Text MicroRNA-146a-5p attenuates irradiation-induced and LPS-induced hepatic stellate cell activation and hepatocyte apoptosis through inhibition of TLR4 pathway Yuhan Chen, Zhifeng Wu, Baoying Yuan, Yinying Dong, Li Zhang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0038-z Abstract | Full Text Human colorectal cancer-derived mesenchymal stem cells promote colorectal cancer progression through IL-6/JAK2/STAT3 signaling Xiaochao Zhang, Fayong Hu, Geng Li, Guodong Li, Xi Yang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0176-3 Abstract | Full Text The histone methyltransferase DOT1L inhibits osteoclastogenesis and protects against osteoporosis Yanpan Gao & Wei Ge Cell Death & Disease 2018 9: 10.1038/s41419-017-0040-5 Abstract | Full Text Preclinical evaluation of antitumor activity of the proteasome inhibitor MLN2238 (ixazomib) in hepatocellular carcinoma cells Giuseppa Augello, Martina Modica, Antonina Azzolina, Roberto Puleio, Giovanni Cassata et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0195-0 Abstract | Full Text Efficacy of MEK inhibition in a K-Ras-driven cholangiocarcinoma preclinical model Mingjie Dong, Xianqiong Liu, Katja Evert, Kirsten Utpatel, Michele Peters et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0183-4 Abstract | Full Text Monoglyceride lipase gene knockout in mice leads to increased incidence of lung adenocarcinoma Renyan Liu, Xin Wang, Christopher Curtiss, Steve Landas, Rong Rong et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0188-z Abstract | Full Text Insulin-like growth factor 2 is a key mitogen driving liver repopulation in mice Min-Jun Wang, Fei Chen, Qing-Gui Liu, Chang-Cheng Liu, Hao Yao et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0186-1 Abstract | Full Text NDRG2 contributes to cisplatin sensitivity through modulation of BAK-to-Mcl-1 ratio Soojong Park, Sang-Seok Oh, Ki Won Lee, Yeon-Kyeong Lee, Nae Yu Kim et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0184-3 Abstract | Full Text Intrinsic apoptotic pathway activation increases response to anti-estrogens in luminal breast cancers Michelle M. Williams, Linus Lee, Thomas Werfel, Meghan M. Morrison Joly, Donna J. Hicks et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0072-x Abstract | Full Text MCL-1 is a prognostic indicator and drug target in breast cancer Kirsteen J. Campbell, Sandeep Dhayade, Nicola Ferrari, Andrew H. Sims, Emma Johnson et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0035-2 Abstract | Full Text miR-181a-5p suppresses invasion and migration of HTR-8/SVneo cells by directly targeting IGF2BP2 Liang Wu, Wen-yan Song, Ya Xie, Lin-li Hu, Xiao-man Hou et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0045-0 Abstract | Full Text Ecotropic viral integration site 1 promotes metastasis independent of epithelial mesenchymal transition in colon cancer cells Kasturi Bala Nayak, I. S. Sajitha, T. R. Santhosh Kumar & Soumen Chakraborty Cell Death & Disease 2018 9: 10.1038/s41419-017-0036-1 Abstract | Full Text Plumbagin inhibits the proliferation and survival of esophageal cancer cells by blocking STAT3-PLK1-AKT signaling Ying-Ya Cao, Jing Yu, Ting-Ting Liu, Kai-Xia Yang, Li-Yan Yang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0068-6 Abstract | Full Text MiR-770 suppresses the chemo-resistance and metastasis of triple negative breast cancer via direct targeting of STMN1 Yaming Li, Yiran Liang, Yuting Sang, Xiaojin Song, Hanwen Zhang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0030-7 Abstract | Full Text Oridonin exerts anticancer effect on osteosarcoma by activating PPAR-γ and inhibiting Nrf2 pathway Ying Lu, Yang Sun, Jianwei Zhu, Lisha Yu, Xiubo Jiang et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0031-6 Abstract | Full Text NF-κB/miR-223-3p/ARID1A axis is involved in Helicobacter pylori CagA-induced gastric carcinogenesis and progression Fenghua Yang, Yugang Xu, Chao Liu, Cunying Ma, Shuiyan Zou et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0020-9 Abstract | Full Text The expression of inhibitor of bruton’s tyrosine kinase gene is progressively up regulated in the clinical course of chronic lymphocytic leukaemia conferring resistance to apoptosis Francesco Albano, Federico Chiurazzi, Selena Mimmi, Eleonora Vecchio, Arianna Pastore et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0026-3 Abstract | Full Text miRNA-3473b contributes to neuroinflammation following cerebral ischemia Xiaoyu Wang, Shuangshuang Chen, Jingshu Ni, Jian Cheng, Jia Jia et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0014-7 Abstract | Full Text Glucose-6-phosphate dehydrogenase is indispensable in embryonic development by modulation of epithelial-mesenchymal transition via the NOX/Smad3/miR-200b axis Yi-Hsuan Wu, Ying-Hsuan Lee, Hung-Yu Shih, Shih-Hsiang Chen, Yi-Chuan Cheng et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0005-8 Abstract | Full Text EphB3 signaling induces cortical endothelial cell death and disrupts the blood–brain barrier after traumatic brain injury Poincyane Assis-Nascimento, Yanina Tsenkina & Daniel J. Liebl Cell Death & Disease 2018 9: 10.1038/s41419-017-0016-5 Abstract | Full Text Neogenin, a regulator of adult hippocampal neurogenesis, prevents depressive-like behavior Dong Sun, Xiang-Dong Sun, Lu Zhao, Dae-Hoon Lee, Jin-Xia Hu et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0019-2 Abstract | Full Text Lamin A/C augments Th1 differentiation and response against vaccinia virus and Leishmania major Raquel Toribio-Fernández, Virginia Zorita, Vera Rocha-Perugini, Salvador Iborra, Gloria Martínez del Hoyo et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0007-6 Abstract | Full Text Epithelial cell adhesion molecule overexpression regulates epithelial-mesenchymal transition, stemness and metastasis of nasopharyngeal carcinoma cells via the PTEN/AKT/mTOR pathway Meng-He Wang, Rui Sun, Xiao-Min Zhou, Mei-Yin Zhang, Jia-Bin Lu et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0013-8 Abstract | Full Text Short-term retinoic acid treatment sustains pluripotency and suppresses differentiation of human induced pluripotent stem cells Maria Teresa De Angelis, Elvira Immacolata Parrotta, Gianluca Santamaria & Giovanni Cuda Cell Death & Disease 2018 9: 10.1038/s41419-017-0028-1 Abstract | Full Text The epigenetically regulated miR-494 associates with stem-cell phenotype and induces sorafenib resistance in hepatocellular carcinoma Daniela Pollutri, Clarissa Patrizi, Sara Marinelli, Catia Giovannini, Elena Trombetta et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0076-6 Abstract | Full Text EGBMMDA: Extreme Gradient Boosting Machine for MiRNA-Disease Association prediction Xing Chen, Li Huang, Di Xie & Qi Zhao Cell Death & Disease 2018 9: 10.1038/s41419-017-0003-x Abstract | Full Text Anti-Trop2 blockade enhances the therapeutic efficacy of ErbB3 inhibition in head and neck squamous cell carcinoma Nathan Redlich, Anthony M. Robinson, Kwangok P. Nickel, Andrew P. Stein, Deric L. Wheeler et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0029-0 Abstract | Full Text Oxidative stress preconditioning of mouse perivascular myogenic progenitors selects a subpopulation of cells with a distinct survival advantage in vitro and in vivo Cesare Gargioli, Giuseppina Turturici, Maria M. Barreca, Walter Spinello, Claudia Fuoco et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0012-9 Abstract | Full Text Comment   Glutamine metabolism, the Achilles heel for medulloblastoma tumor Maria Victoria Niklison-Chirou Cell Death & Disease 2018 9: 10.1038/s41419-017-0117-1 Abstract | Full Text Suppressing autophagy: a strategy by Escherichia coli O157:H7 for its survival on host epithelial cells Yansong Xue & Mei-Jun Zhu Cell Death & Disease 2018 9: 10.1038/s41419-017-0095-3 Abstract | Full Text One protein, different cell fate: the differential outcome of depleting GRP75 during oxidative stress in neurons Birgit Honrath, Carsten Culmsee & Amalia M Dolga Cell Death & Disease 2018 9: 10.1038/s41419-017-0148-7 Abstract | Full Text Co-selected mutations in VCP: a novel mechanism of resistance to VCP inhibitors Prabhakar Bastola & Jeremy Chien Cell Death & Disease 2018 9: 10.1038/s41419-017-0049-9 Abstract | Full Text How BMP-2 induces EMT and breast cancer stemness through Rb and CD44? Guanglin Zhang, Peide Huang, Anan Chen, Weiyi He, Zhen Li et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0037-0 Abstract | Full Text Correspondence   Rare mutations inapoptosis related genes APAF1, CASP9, and CASP3 contribute to human neural tube defects Xiangyu Zhou, Weijia Zeng, Huili Li, Haitao Chen, Gang Wei et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0096-2 Abstract | Full Text Puromycin labeling does not allow protein synthesis to be measured in energy-starved cells Ran Marciano, Gabriel Leprivier & Barak Rotblat Cell Death & Disease 2018 9: 10.1038/s41419-017-0056-x Abstract | Full Text Review Article   N6-methyladenosine links RNA metabolism to cancer progression   Cell Death & Disease 2018 9: 10.1038/s41419-017-0129-x Abstract | Full Text Regulatory B cells: the cutting edge of immune tolerance in kidney transplantation Bo Peng, Yingzi Ming & Cheng Yang Cell Death & Disease 2018 9: 10.1038/s41419-017-0152-y Abstract | Full Text Immunological consequences of kidney cell death   Cell Death & Disease 2018 9: 10.1038/s41419-017-0057-9 Abstract | Full Text Functional and structural damage of neurons by innate immune mechanisms during neurodegeneration Christina Ising & Michael T. Heneka Cell Death & Disease 2018 9: 10.1038/s41419-017-0153-x Abstract | Full Text Cell death-based treatment of glioblastoma Simone Fulda Cell Death & Disease 2018 9: 10.1038/s41419-017-0021-8 Abstract | Full Text Necroptosis and neutrophil-associated disorders Xiaoliang Wang, Shida Yousefi & Hans-Uwe Simon Cell Death & Disease 2018 9: 10.1038/s41419-017-0058-8 Abstract | Full Text Cell death-based approaches in treatment of the urinary tract-associated diseases: a fight for survival in the killing fields Diego Martin-Sanchez, Miguel Fontecha-Barriuso, Maria Dolores Sanchez-Niño, Adrian M. Ramos, Ramiro Cabello et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0043-2 Abstract | Full Text Cellular death, reactive oxygen species (ROS) and diabetic complications Caroline Maria Oliveira Volpe, Pedro Henrique Villar-Delfino, Paula Martins Ferreira dos Anjos & José Augusto Nogueira-Machado Cell Death & Disease 2018 9: 10.1038/s41419-017-0135-z Abstract | Full Text Cell death-based treatments of melanoma:conventional treatments and new therapeutic strategies Gianfranco Mattia, Rossella Puglisi, Barbara Ascione, Walter Malorni, Alessandra Carè et al. Cell Death & Disease 2018 9: 10.1038/s41419-017-0059-7 Abstract | Full Text Cell death-based treatment of neuroblastoma Kadri Valter, Boris Zhivotovsky & Vladimir Gogvadze Cell Death & Disease 2018 9: 10.1038/s41419-017-0060-1 Abstract | Full Text STIL balancing primary microcephaly and cancer   Cell Death & Disease 2018 9: 10.1038/s41419-017-0101-9 Abstract | Full Text Molecular and physiological roles of the adaptor protein CARD9 in immunity Xiaoming Zhong, Bin Chen, Liang Yang & Zhiwen Yang Cell Death & Disease 2018 9: 10.1038/s41419-017-0084-6 Abstract | Full Text Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here. Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. 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