Journal of Antibiotics - Table of Contents alert Volume 71 Issue 2

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TABLE OF CONTENTS Special Issue Dedicated to K. C. Nicolaou: Groundbreaking work at the frontiers of total synthesis and chemical biology The February issue of The Journal of Antibiotics is dedicated to Professor KC Nicolaou for his great scientific contribution to total synthesis of highly complex and biologically important natural products. We are grateful to each of the contributors worldwide and particularly to Prof. Nicolaou for his continuous support with organizing this effort. We would like to thank Drs Keiichi Ajito and Nicolas Winssinger for their great devotion in planning and coordinating this issue. The Journal of Antibiotics Volume 71, Issue 2 (February 2018) In this issue Editorial Review Articles Original Articles Notes Communication to the Editor Corrigenda Also new AOP   Sign up for e-alerts Recommend to your library Web feed Subscribe Editorial Biography of Professor Nicolaou: a journey to the extremes of molecular complexity Nicolas Winssinger The Journal of Antibiotics 2018 71: 149 - 150; January 29, 2018; 10.1038/ja.2017.144   Abstract | Full Text Professor KC Nicolaou expanded the world of synthetic organic chemistry by total synthesis and his laboratories have fostered many talented researchers Keiichi Ajito The Journal of Antibiotics 2018 71: 151 - 152; January 29, 2018; 10.1038/ja.2017.147   Abstract | Full Text Review Articles A brief history of antibiotics and select advances in their synthesis Kyriacos C Nicolaou & Stephan Rigol The Journal of Antibiotics 2017 71: 153 - 184; July 05, 2017; 10.1038/ja.2017.62   Abstract | Full Text Total synthesis of architecturally complex indole terpenoids: strategic and tactical evolution Yike Zou & Amos B Smith III The Journal of Antibiotics 2017 71: 185 - 204; August 30, 2017; 10.1038/ja.2017.94   Abstract | Full Text Chemotherapeutics overcoming nonsense mutation-associated genetic diseases: medicinal chemistry of negamycin Akihiro Taguchi, Keisuke Hamada & Yoshio Hayashi The Journal of Antibiotics 2017 71: 205 - 214; September 27, 2017; 10.1038/ja.2017.112   Abstract | Full Text Challenges and discoveries in the total synthesis of complex polyketide natural products Ian Paterson & Nelson Yuen Sum Lam The Journal of Antibiotics 2017 71: 215 - 233; October 25, 2017; 10.1038/ja.2017.111   Abstract | Full Text Original Articles Enantiospecific total synthesis of the squalene synthase inhibitors (–)-CJ-13,982 and its enantiomer from a common intermediate Dayna Sturgess, Zongjia Chen, Jonathan M White & Mark A Rizzacasa The Journal of Antibiotics 2017 71: 234 - 239; October 25, 2017; 10.1038/ja.2017.127   Abstract | Full Text Total synthesis of (+)-lysergic acid Rentaro Kanno, Satoshi Yokoshima, Motomu Kanai & Tohru Fukuyama The Journal of Antibiotics 2017 71: 240 - 247; July 19, 2017; 10.1038/ja.2017.80   Abstract | Full Text Synthesis of deoxyelephantopin analogues Roman Lagoutte, Christelle Serba & Nicolas Winssinger The Journal of Antibiotics 2017 71: 248 - 256; November 01, 2017; 10.1038/ja.2017.132   Abstract | Full Text Formal synthesis of englerin A utilizing regio- and diastereoselective [4+3] cycloaddition Shuichi Hagihara, Kengo Hanaya, Takeshi Sugai & Mitsuru Shoji The Journal of Antibiotics 2017 71: 257 - 262; August 02, 2017; 10.1038/ja.2017.91   Abstract | Full Text Progress towards the total synthesis of hamigerans C and D: a direct approach to an elaborated 6-7-5 carbocyclic core Douglas Charles Duquette, Thomas Jensen & Brian Mark Stoltz The Journal of Antibiotics 2017 71: 263 - 267; September 06, 2017; 10.1038/ja.2017.96   Abstract | Full Text Toward the total synthesis of luminamicin; an anaerobic antibiotic: construction of highly functionalized cis-decalin containing a bridged ether moiety Hiroyasu Ando, Aoi Kimishima, Motoyoshi Ohara, Tomoyasu Hirose, Takanori Matsumaru et al. The Journal of Antibiotics 2017 71: 268 - 272; July 05, 2017; 10.1038/ja.2017.77   Abstract | Full Text Halistanol sulfates I and J, new SIRT1–3 inhibitory steroid sulfates from a marine sponge of the genus Halichondria Fumiaki Nakamura, Norio Kudo, Yuki Tomachi, Akiko Nakata, Misao Takemoto et al. The Journal of Antibiotics 2017 71: 273 - 278; November 29, 2017; 10.1038/ja.2017.145   Abstract | Full Text Using experimental evolution to identify druggable targets that could inhibit the evolution of antimicrobial resistance Heer H Mehta, Amy G Prater & Yousif Shamoo The Journal of Antibiotics 2017 71: 279 - 286; September 20, 2017; 10.1038/ja.2017.108   Abstract | Full Text Heterocyclyl tetracyclines. 2. 7-Methoxy-8-pyrrolidinyltetracyclines: discovery of TP-2758, a potent, orally efficacious antimicrobial against Gram-negative pathogens Cuixiang Sun, Yonghong Deng, Diana K Hunt, Corey Fyfe, Chi-Li Chen et al. The Journal of Antibiotics 2017 71: 287 - 297; July 26, 2017; 10.1038/ja.2017.86   Abstract | Full Text Synthesis and SARs of novel lincomycin derivatives Part 5: optimization of lincomycin analogs exhibiting potent antibacterial activities by chemical modification at the 6- and 7-positions Yoshinari Wakiyama, Ko Kumura, Eijiro Umemura, Satomi Masaki, Kazutaka Ueda et al. The Journal of Antibiotics 2017 71: 298 - 317; November 01, 2017; 10.1038/ja.2017.114   Abstract | Full Text Large-scale preparation of key building blocks for the manufacture of fully synthetic macrolide antibiotics Philip C Hogan, Chi-Li Chen, Kristen M Mulvihill, Jonathan F Lawrence, Eric Moorhead et al. The Journal of Antibiotics 2017 71: 318 - 325; October 11, 2017; 10.1038/ja.2017.116   Abstract | Full Text A three-component coupling approach to the ACE-ring substructure of C19-diterpene alkaloids Kosuke Minagawa, Daisuke Urabe & Masayuki Inoue The Journal of Antibiotics 2017 71: 326 - 332; June 14, 2017; 10.1038/ja.2017.69   Abstract | Full Text Notes Isolation and structure elucidation of lipopeptide antibiotic taromycin B from the activated taromycin biosynthetic gene cluster Kirk A Reynolds, Hanna Luhavaya, Jie Li, Samira Dahesh, Victor Nizet et al. The Journal of Antibiotics 2017 71: 333 - 338; November 29, 2017; 10.1038/ja.2017.146   Abstract | Full Text Albiducins A and B, salicylaldehyde antibiotics from the ash tree-associated saprotrophic fungus Hymenoscyphus albidus Sandra Halecker, Frank Surup, Halvor Solheim & Marc Stadler The Journal of Antibiotics 2017 71: 339 - 341; June 07, 2017; 10.1038/ja.2017.66   Abstract | Full Text Synthesis of unique spirocyclic orthoester-type derivatives of isothiazolo[4,3-d]pyrimidine nucleosides Alexander R Rovira & Yitzhak Tor The Journal of Antibiotics 2017 71: 342 - 344; July 26, 2017; 10.1038/ja.2017.87   Abstract | Full Text Communication to the Editor Discovery of 2-hydroxyarbekacin, a new aminoglycoside antibiotic with reduced nephrotoxicity Yoshiaki Takahashi, Eijiro Umemura, Yoshihiko Kobayashi, Shoichi Murakami, Toru Nawa et al. The Journal of Antibiotics 2017 71: 345 - 347; June 28, 2017; 10.1038/ja.2017.60   Abstract | Full Text Corrigenda Corrigendum: Total synthesis and absolute configuration of avenolide, extracellular factor in Streptomyces avermitilis Miho Uchida, Satoshi Takamatsu, Shiho Arima, Kiyoko T Miyamoto, Shigeru Kitani et al. The Journal of Antibiotics 2018 71: 348 - 348; January 29, 2018; 10.1038/ja.2017.148   Abstract | Full Text Corrigendum: Microbial metabolites and derivatives targeted at inflammation and bone diseases therapy: chemistry, biological activity and pharmacology Hayamitsu Adachi, Koichi Nakae, Shuichi Sakamoto, Chisato Nosaka, Sonoko Atsumi et al. The Journal of Antibiotics 2018 71: 349 - 349; January 29, 2018; 10.1038/ja.2017.149   Abstract | Full Text Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here. 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