Nature Reviews Cancer contents January 2018 Volume 18 Number 1 1-63

If you are unable to see the message below, click here to view.
 

TABLE OF CONTENTS
January 2018 Volume 18 Number 1
2016 2-year Impact Factor 37.147 Journal Metrics 2-year Median 28	In this issue Research Highlights Reviews Perspectives   Also this month Article series: Cancer origins  Featured article: Non-coding RNA networks in cancer Eleni Anastasiadou, Leni S. Jacob & Frank J. Slack
Subscribe   Facebook   RSS   Recommend to library   Twitter
Advertisement
AACR Annual Meeting 2018  Join us April 14-18, 2018 in Chicago, IL as the AACR Annual Meeting highlights the work of the best minds in cancer research and medicine from institutions all over the world. Learn more.
RESEARCH HIGHLIGHTS   Top Tumour microenvironment: Microbes matter p1 | doi:10.1038/nrc.2017.120 The gut microbiome can modulate the clinical response to anti-programmed cell death protein 1 (PD1) immunotherapy in patients with solid tumours. PDF Immunotherapy: Burning fences p2 | doi:10.1038/nrc.2017.119 New research published in Nature now demonstrates that immune checkpoint blockade can alleviate hepatocellular carcinoma progression in patients with nonalcoholic steatohepatitis (NASH) by inhibiting immunosuppressive immunoglobulin A-producing cells in the liver. PDF Metabolism: Adapting to the environment p2 | doi:10.1038/nrc.2017.123 Alvarez, Sviderskiy et al. have identified a pathway that allows primary lung tumour cells or lung metastatic breast tumour cells to survive in the high oxygen concentrations present in the lung. PDF Targeted therapies: Strategies for mature T cell cancers p3 | doi:10.1038/nrc.2017.124 Two new papers provide insight into the future treatment of mature T cell cancers. PDF   Nature Reviews Cancer JOBS of the week PhD Positions in Cancer Research at the German Cancer Research Center German Cancer Research Center (DKFZ). Assistant or Associate Professor - Genome Editing & Functional Cancer Genomics Children's Hospital of Philadelphia Post-doctoral or Master's level position - Computational Biology Dana-Farber Cancer Institute (DFCI) Medical Oncologist, GU Cancers Princess Margaret Cancer Centre Post doctoral fellow in cancer genomics Indiana University - Purdue University Indianapolis More Science jobs from Nature Reviews Cancer EVENT World Cancer Congress 18.03.18 New Delhi, India More science events from
REVIEWS		Top
Non-coding RNA networks in cancer Eleni Anastasiadou, Leni S. Jacob & Frank J. Slack p5 | doi:10.1038/nrc.2017.99 Non-coding RNAs (ncRNAs) are functional molecules that regulate physiological programmes in developmental and disease contexts. This Review article discusses the complex networks of interactions that ncRNAs engage in and how these confer oncogenic or tumour-suppressive effects in cancer. Abstract | Full Text | PDF
Article series: Cancer origins An evolutionary perspective on field cancerization Kit Curtius, Nicholas A. Wright & Trevor A. Graham p19 | doi:10.1038/nrc.2017.102 Field cancerization underlies the development of many types of cancer. This Review examines the biological mechanisms that drive the evolution of cancerized fields and discusses how measuring field evolution could improve cancer risk prediction in patients with pre-malignant disease. Abstract | Full Text | PDF
Sphingolipid metabolism in cancer signalling and therapy Besim Ogretmen p33 | doi:10.1038/nrc.2017.96 Sphingolipids, specifically ceramide and sphingosine-1-phosphate, have opposing roles in regulating cancer cell death and survival, respectively. This Review discusses the mechanistic and clinical studies of sphingolipid signalling and metabolism in cancer, highlighting current and emerging therapeutic strategies to target these bioactive lipids. Abstract | Full Text | PDF
PERSPECTIVES		Top
OPINION Ribosome biogenesis in cancer: new players and therapeutic avenues Joffrey Pelletier, George Thomas & Sinisa Volarevic p51 | doi:10.1038/nrc.2017.104 Causal associations have been established between dysregulated ribosome biogenesis and cancer. In this Opinion article, the authors highlight emerging mechanistic data on the molecular basis of ribosomes in cancer and offer their perspective on how these advances present therapeutic opportunities. Abstract | Full Text | PDF
Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here. Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. For event advertising opportunities across the Nature Publishing Group portfolio please contact natureevents@nature.com More Nature Events

You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/myaccount (You will need to log in to be recognised as a nature.com registrant). For further technical assistance, please contact our registration department For print subscription enquiries, please contact our subscription department For other enquiries, please contact our feedback department Springer Nature | One New York Plaza, Suite 4500 | New York | NY 10004-1562 | USA Springer Nature's worldwide offices: London - Paris - Munich - New Delhi - Tokyo - Melbourne San Diego - San Francisco - Washington - New York - Boston Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at The Campus, 4 Crinan Street, London, N1 9XW. © 2018 Macmillan Publishers Limited, part of Springer Nature. All Rights Reserved.