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Visit our open access funding page or contact openaccess@nature.com to learn more about APC funding. | | | | | | Latest Editorial | View all Editorials | | | | | Rising to the challenge of surging seas OPEN | | | Amid increasingly extreme projections for future sea-level rise, concerns are mounting that policymakers are struggling to keep abreast of fast-paced scientific developments. To ease this burden and increase the accessibility of published research, we have compiled an editor-curated collection of the most recent sea-level rise articles published at Nature Communications. | | | 10 July 2017 | doi: 10.1038/ncomms16127 | | | | | | | | Latest Articles | View all Articles | | | | | A neural link between generosity and happiness OPEN | | | Soyoung Q. Park, Thorsten Kahnt, Azade Dogan, Sabrina Strang, Ernst Fehr and Philippe N. Tobler | | | Generous behaviour increases happiness, but the neural underpinnings of this link are unknown. Here, authors show that promising to be generous changes the neural response in the temporo-parietal junction, and that the connection between this region and the ventral striatum was related to happiness. | | | 11 July 2017 | doi: 10.1038/ncomms15964 | | |
| Innate scavenger receptor-A regulates adaptive T helper cell responses to pathogen infection OPEN | | | Zhipeng Xu, Lei Xu, Wei Li, Xin Jin, Xian Song, Xiaojun Chen, Jifeng Zhu, Sha Zhou, Yong Li, Weiwei Zhang, Xiaoxiao Dong, Xiaowei Yang, Feng Liu, Hui Bai, Qi Chen and Chuan Su | | | Scavenger receptors can function as pattern recognition receptors to sense infection. Here the authors show that, in response to worm and bacterial infection, scavenger receptor class A prevents nuclear localization of IRF5 and thereby drives M2 polarization and associated type 2 immune responses. | | | 11 July 2017 | doi: 10.1038/ncomms16035 | | |
| Dual loss of human POLQ and LIG4 abolishes random integration OPEN | | | Shinta Saito, Ryo Maeda and Noritaka Adachi | | | Homologous recombination mediated gene targeting is highly inefficient in human cells due to random integration events, Here the authors show that dual repression of polymerase θ and DNA ligase IV eliminate random integration events. | | | 11 July 2017 | doi: 10.1038/ncomms16112 | | |
| Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein OPEN | | | Yong Lei, Xiaotian Zhang, Jianzhong Su, Mira Jeong, Michael C. Gundry, Yung-Hsin Huang, Yubin Zhou, Wei Li and Margaret A. Goodell | | | Understanding how DNA methylation regulates gene expression requires the capacity to deploy it to regions of interest. The authors generate a highly rapid and locus-specific CpG methylation tool by fusing dCas9 to MQ1 DNA methyltransferase and show efficacy at multiple sites in vitro and in vivo. | | | 11 July 2017 | doi: 10.1038/ncomms16026 | | |
| Somatic chromosomal engineering identifies BCAN-NTRK1 as a potent glioma driver and therapeutic target OPEN | | | Peter J. Cook, Rozario Thomas, Ram Kannan, Esther Sanchez de Leon, Alexander Drilon, Marc K. Rosenblum, Maurizio Scaltriti, Robert Benezra and Andrea Ventura | | | The use of mouse models has been an invaluable resource in cancer research but their generation is lengthy and costly. Here the authors describe an approach to generate engineered mouse models carrying specific gene fusions and, as a proof of principle, show that Bcan-Ntrk1 fusion leads to glioblastomas. | | | 11 July 2017 | doi: 10.1038/ncomms15987 | | |
| The endothelial transcription factor ERG mediates Angiopoietin-1-dependent control of Notch signalling and vascular stability OPEN | | | A. V. Shah, G. M. Birdsey, C. Peghaire, M. E. Pitulescu, N. P. Dufton, Y. Yang, I. Weinberg, L. Osuna Almagro, L. Payne, J. C. Mason, H. Gerhardt, R. H. Adams and A. M. Randi | | | Vascular maturation and stability is regulated by Notch and Angiopoietin-1/Tie2 signalling. Here, Shah et al. show that the transcription factor ERG coordinates the Ang1, Notch and Wnt/β-catenin pathways to promote vascular maturation and stability. | | | 11 July 2017 | doi: 10.1038/ncomms16002 | | |
| R-Spondin chromosome rearrangements drive Wnt-dependent tumour initiation and maintenance in the intestine OPEN | | | Teng Han, Emma M. Schatoff, Charles Murphy, Maria Paz Zafra, John E. Wilkinson, Olivier Elemento and Lukas E. Dow | | | Recent evidence suggests that EIF3E–RSPO2 and PTPRK–RSPO3 gene fusions promote colorectal cancer. Here, using CRISPR-mediated genome editing, the authors show that endogenous Rspo2 or Rspo3 chromosome rearrangements result in intestinal tumours extremely sensitive to Wnt ligand inhibition. | | | 11 July 2017 | doi: 10.1038/ncomms15945 | | |
| A volumetric three-dimensional digital light photoactivatable dye display OPEN | | | Shreya K. Patel, Jian Cao and Alexander R. Lippert | | | Despite living in a three-dimensional world, almost all information in our society is conveyed in a two-dimensional format. Here, the authors provide a technique for the generation of spatially accurate and high-resolution three-dimensional images using fluorescent photoswitch chemistry. | | | 11 July 2017 | doi: 10.1038/ncomms15239 | | |
| Enhanced electron dephasing in three-dimensional topological insulators OPEN | | | Jian Liao, Yunbo Ou, Haiwen Liu, Ke He, Xucun Ma, Qi-Kun Xue and Yongqing Li | | | The electron dephasing mechanism in topological insulators remains unclear. Here, Liao et al. report a sublinear power law for the temperature dependence of the electron dephasing rate in (Bi,Sb)2Te3 thin films, representing a surprising deviation from conventional behaviours in two-dimensional electron systems. | | | 11 July 2017 | doi: 10.1038/ncomms16071 | | |
| Exploring the hidden interior of the Earth with directional neutrino measurements OPEN | | | Michael Leyton, Stephen Dye and Jocelyn Monroe | | | The detection of Earth’s anti neutrino emission from potassium and the mantle remain elusive. Here the authors propose a method for measuring potassium and mantle geo-neutrinos by detecting their elastic scattering on electrons with direction-sensitive detectors. | | | 10 July 2017 | doi: 10.1038/ncomms15989 | | |
| Global mismatch between fishing dependency and larval supply from marine reserves OPEN | | | Marco Andrello, François Guilhaumon, Camille Albouy, Valeriano Parravicini, Joeri Scholtens, Philippe Verley, Manuel Barange, U. Rashid Sumaila, Stéphanie Manel and David Mouillot | | | The effectiveness of marine reserves relies on whether they supply substantial recruitment outside their boundaries. Here, Andrello and colleagues use models of larval fish dispersal to show that countries most dependent on coastal fisheries receive the lowest larval supplies from marine reserves. | | | 10 July 2017 | doi: 10.1038/ncomms16039 | | |
| Crosstalk and the evolvability of intracellular communication OPEN | | | Michael A. Rowland, Joseph M. Greenbaum and Eric J. Deeds | | | The evolutionary rationale behind the extensive crosstalk between Metazoan signalling pathways remains elusive. Here the authors provide evidence that crosstalk in the human signalling network evolves as a means to allow efficient diversification of cellular responses to the same signals between different cell types. | | | 10 July 2017 | doi: 10.1038/ncomms16009 | | |
| An exported protein-interacting complex involved in the trafficking of virulence determinants in Plasmodium-infected erythrocytes OPEN | | | Steven Batinovic, Emma McHugh, Scott A. Chisholm, Kathryn Matthews, Boiyin Liu, Laure Dumont, Sarah C. Charnaud, Molly Parkyn Schneider, Paul R. Gilson, Tania F. de Koning-Ward, Matthew W. A. Dixon and Leann Tilley | | | Plasmodium-infected red blood cells export virulence factors, such as PfEMP1, to the cell surface. Here, the authors identify a protein complex termed EPIC that interacts with PfEMP1 during export, and they show that knockdown of an EPIC component affects parasite virulence. | | | 10 July 2017 | doi: 10.1038/ncomms16044 | | |
| Ancient hydrothermal seafloor deposits in Eridania basin on Mars OPEN | | | Joseph R. Michalski, Eldar Z. Noe Dobrea, Paul B. Niles and Javier Cuadros | | | The Eridania basin on Mars was once the site of a vast inland sea. Here, the authors show that the most ancient materials in the Eridania basin were formed in a deep-water hydrothermal setting and may be an analogue for early environmental conditions on Earth. | | | 10 July 2017 | doi: 10.1038/ncomms15978 | | |
| Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma OPEN | | | Jianguo Huang, Mark Chen, Melodi Javid Whitley, Hsuan-Cheng Kuo, Eric S. Xu, Andrea Walens, Yvonne M. Mowery, David Van Mater, William C. Eward, Diana M. Cardona, Lixia Luo, Yan Ma, Omar M. Lopez, Christopher E. Nelson, Jacqueline N. Robinson-Hamm, Anupama Reddy, Sandeep S. Dave, Charles A. Gersbach, Rebecca D. Dodd and David G. Kirsch et al. | | | Site-specific recombination and CRISPR-Cas9 have been used to generate genetically engineered mouse models of cancer. Here the authors compare sarcomas generated using both systems and see similar genetic and cellular phenotypes, suggesting CRISPR-Cas9 can be used to rapidly generate sarcoma models. | | | 10 July 2017 | doi: 10.1038/ncomms15999 | | |
| Controlled spatial separation of spins and coherent dynamics in spin-orbit-coupled nanostructures OPEN | | | Shun-Tsung Lo, Chin-Hung Chen, Ju-Chun Fan, L. W. Smith, G. L. Creeth, Che-Wei Chang, M. Pepper, J. P. Griffiths, I. Farrer, H. E. Beere, G. A. C. Jones, D. A. Ritchie and Tse-Ming Chen | | | The development of spintronics relies on the exploitation of techniques to control different spin species separately. Here the authors make use of spin orbit coupling to spatially separate two spin populations and control the subsequent coherent evolution. | | | 10 July 2017 | doi: 10.1038/ncomms15997 | | |
| Dehydration of subducting slow-spread oceanic lithosphere in the Lesser Antilles OPEN | | | Michele Paulatto, Mireille Laigle, Audrey Galve, Philippe Charvis, Martine Sapin, Gaye Bayrakci, Mikael Evain and Heidrun Kopp | | | During subduction water is transported into the mantle, but constraining its release remains challenging. Here, using seismic tomography of the Lesser Antilles arc, the authors track the multistage dehydration of the slab and its lateral variations associated with heterogeneous slab composition. | | | 10 July 2017 | doi: 10.1038/ncomms15980 | | |
| Instructing cells with programmable peptide DNA hybrids OPEN | | | Ronit Freeman, Nicholas Stephanopoulos, Zaida Álvarez, Jacob A Lewis, Shantanu Sur, Chris M Serrano, Job Boekhoven, Sungsoo S. Lee and Samuel I. Stupp | | | The extracellular matrix can affect cell behaviour both physically and biochemically. Here, the authors developed a substrate that is based on peptides and nucleic acids hybrids that can dynamically present signals upon demand which regulate cell adhesion and migration, thereby controlling cell organisation. | | | 10 July 2017 | doi: 10.1038/ncomms15982 | | |
| The self-inhibitory nature of metabolic networks and its alleviation through compartmentalization OPEN | | | Mohammad Tauqeer Alam, Viridiana Olin-Sandoval, Anna Stincone, Markus A. Keller, Aleksej Zelezniak, Ben F. Luisi and Markus Ralser | | | Metabolites act as enzyme inhibitors, but their global impact on metabolism has scarcely been considered. Here, the authors generate a human genome-wide metabolite-enzyme inhibition network, and find that inhibition occurs largely due to limited structural diversity of metabolites, leading to a global constraint on metabolism which subcellular compartmentalization minimizes. | | | 10 July 2017 | doi: 10.1038/ncomms16018 | | |
| Western tropical Pacific multidecadal variability forced by the Atlantic multidecadal oscillation OPEN | | | Cheng Sun, Fred Kucharski, Jianping Li, Fei-Fei Jin, In-Sik Kang and Ruiqiang Ding | | | The western tropical Pacific is a main source of heat and moisture for the global atmosphere, yet the mechanism for the multidecadal sea surface temperature variability in this region remains unknown. Here, the authors show that this variability is forced by the remote Atlantic multidecadal oscillation | | | 07 July 2017 | doi: 10.1038/ncomms15998 | | |
| Understanding extreme sea levels for broad-scale coastal impact and adaptation analysis OPEN | | | T. Wahl, I. D. Haigh, R. J. Nicholls, A. Arns, S. Dangendorf, J. Hinkel and A. B. A. Slangen | | | Uncertainties in contemporary extreme sea levels (ESL) from mean sea level rise (SLR) projections have been overlooked in broad-scale risk and adaptation studies. Here, the authors quantify the uncertainties in present-day global ESL estimates and find that they exceed those from global SLR projections. | | | 07 July 2017 | doi: 10.1038/ncomms16075 | | |
| Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA OPEN | | | María José Lista, Rodrigo Prado Martins, Olivier Billant, Marie-Astrid Contesse, Sarah Findakly, Pierre Pochard, Chrysoula Daskalogianni, Claire Beauvineau, Corinne Guetta, Christophe Jamin, Marie-Paule Teulade-Fichou, Robin Fåhraeus, Cécile Voisset and Marc Blondel | | | Cells infected with Epstein-Barr virus (EBV) express the virus-encoded EBNA1, which is essential for viral genome maintenance but also highly antigenic. Here the authors implicate nucleolin as a host factor that mediates the repression of EBNA1-derived antigenic peptides through binding of the G4-quadruplex structure present within the EBNA1 mRNA. | | | 07 July 2017 | doi: 10.1038/ncomms16043 | | |
| On-chip inter-modal Brillouin scattering OPEN | | | Eric A. Kittlaus, Nils T. Otterstrom and Peter T. Rakich | | | Here, Kittlaus et al. demonstrate stimulated inter-modal Brillouin scattering on-chip. Through this process, a Brillouin interaction couples light fields that propagate in distinct spatial modes of a Brillouin-active silicon waveguide, which may allow a variety of new processes in silicon photonics. | | | 07 July 2017 | doi: 10.1038/ncomms15819 | | |
| Nonlinear cavity optomechanics with nanomechanical thermal fluctuations OPEN | | | Rick Leijssen, Giada R. La Gala, Lars Freisem, Juha T. Muhonen and Ewold Verhagen | | | Optomechanical experiments often assume linear coupling between optical fluctuations and mechanical displacements. Here, Leijssen et al. experimentally demonstrate the nonlinear interaction from thermally induced fluctuations in a sliced nanobeam cavity with high cooperativity. | | | 07 July 2017 | doi: 10.1038/ncomms16024 | | |
| Immobility responses are induced by photoactivation of single glomerular species responsive to fox odour TMT OPEN | | | Harumi Saito, Hirofumi Nishizumi, Satoshi Suzuki, Hideyuki Matsumoto, Nao Ieki, Takaya Abe, Hiroshi Kiyonari, Masahiko Morita, Hideo Yokota, Nozomi Hirayama, Takahiro Yamazaki, Takefumi Kikusui, Kensaku Mori and Hitoshi Sakano | | | The olfactory bulb is arranged in glomeruli defined by their olfactory receptor expression. The authors identify an olfactory receptor for fox odour, TMT, and show that activation of the glomerulus expressing that receptor in mice leads to immobility, but does not lead to other fear behaviours. | | | 07 July 2017 | doi: 10.1038/ncomms16011 | | |
| Greening of the Sahara suppressed ENSO activity during the mid-Holocene OPEN | | | Francesco S. R. Pausata, Qiong Zhang, Francesco Muschitiello, Zhengyao Lu, Léon Chafik, Eva M. Niedermeyer, J. Curt Stager, Kim M. Cobb and Zhengyu Liu | | | Evolution of the El Niño-Southern Oscillation through the Holocene remains uncertain. Here, via fully coupled model simulations, the authors show that increased Saharan vegetation and reduced dust emissions 6 kyr BP significantly affect ENSO variability through changes in the West African Monsoon strength. | | | 07 July 2017 | doi: 10.1038/ncomms16020 | | |
| Thermodynamic stability of ligand-protected metal nanoclusters OPEN | | | Michael G. Taylor and Giannis Mpourmpakis | | | The thermodynamic stability of atomically precise, liganded metal nanoclusters remains poorly understood. Here, the authors use first-principles calculations to derive a new theory that rationalizes the stability of these nanoclusters as a function of their composition and morphology. | | | 07 July 2017 | doi: 10.1038/ncomms15988 | | |
| MiR-497∼195 cluster regulates angiogenesis during coupling with osteogenesis by maintaining endothelial Notch and HIF-1α activity OPEN | | | Mi Yang, Chang-Jun Li, Xi Sun, Qi Guo, Ye Xiao, Tian Su, Man-Li Tu, Hui Peng, Qiong Lu, Qing Liu, Hong-Bo He, Tie-Jian Jiang, Min-Xiang Lei, Mei Wan, Xu Cao and Xiang-Hang Luo | | | H-type endothelium, defined by the high expression of CD31 and endomucin, is found in the bone where it promotes angiogenesis and osteogensis. Here Yang et al. show that the miR-497∼195 cluster regulates the generation and maintenance of the H-type endothelium by controlling the levels of Notch regulator Fbxw7 and the HIF regulator P4HTM. | | | 07 July 2017 | doi: 10.1038/ncomms16003 | | |
| The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs OPEN | | | Aitor Garzia, Seyed Mehdi Jafarnejad, Cindy Meyer, Clément Chapat, Tasos Gogakos, Pavel Morozov, Mehdi Amiri, Maayan Shapiro, Henrik Molina, Thomas Tuschl and Nahum Sonenberg | | | Translation of aberrant mRNAs causes ribosome stalling and translation arrest, followed by recycling of the stalled ribosome complex. Here the authors show that the Zinc Finger Protein 598 (ZNF598/Hel2) is implicated in sensing faulty translation of prematurely polyadenylated mRNAs through the recognition of AAA codons. | | | 07 July 2017 | doi: 10.1038/ncomms16056 | | |
| Meniscus-assisted solution printing of large-grained perovskite films for high-efficiency solar cells OPEN | | | Ming He, Bo Li, Xun Cui, Beibei Jiang, Yanjie He, Yihuang Chen, Daniel O’Neil, Paul Szymanski, Mostafa A. EI-Sayed, Jinsong Huang and Zhiqun Lin | | | The morphology control of metal halide perovskite crystalline films is of importance to enable high-performance solar cells. Here, He et al. use a meniscus-assisted solution-based method to print microsized perovskite grains at 60 °C, which results in high optoelectronic device efficiency of 20%. | | | 07 July 2017 | doi: 10.1038/ncomms16045 | | |
| Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions OPEN | | | Orianne Olivares, Jared R. Mayers, Victoire Gouirand, Margaret E. Torrence, Tristan Gicquel, Laurence Borge, Sophie Lac, Julie Roques, Marie-Noëlle Lavaut, Patrice Berthezène, Marion Rubis, Veronique Secq, Stéphane Garcia, Vincent Moutardier, Dominique Lombardo, Juan Lucio Iovanna, Richard Tomasini, Fabienne Guillaumond, Matthew G. Vander Heiden and Sophie Vasseur et al. | | | Cancer cells adapt their metabolism to survive limited nutrient availability. Here, the authors show that in conditions of limited glucose or glutamine availability, pancreatic ductal adenocarcinoma cells can use collagen-derived proline to foster the TCA cycle and allow cell survival both in vitro and in vivo. | | | 07 July 2017 | doi: 10.1038/ncomms16031 | | |
| El Niño-like teleconnection increases California precipitation in response to warming OPEN | | | Robert J. Allen and Rainer Luptowitz | | | California lies in the transition zone where mid-latitude regions are expected to become wetter and subtropical regions drier, and precipitation projections for the region remain uncertain. Here the authors use a multitude of models to show consistent increases in California precipitation under a business-as-usual scenario. | | | 06 July 2017 | doi: 10.1038/ncomms16055 | | |
| Sea level fall during glaciation stabilized atmospheric CO2 by enhanced volcanic degassing OPEN | | | Jörg Hasenclever, Gregor Knorr, Lars H. Rüpke, Peter Köhler, Jason Morgan, Kristin Garofalo, Stephen Barker, Gerrit Lohmann and Ian R. Hall | | | Ice core data show a breakdown in the long-term temperature-atmospheric CO2 correlation during interglacial-glacial transitions. Here, via a novel modelling approach, the authors reveal marine volcanism, triggered by a fall in sea level, as a likely mechanism for the observed delayed decline in atmospheric CO2. | | | 06 July 2017 | doi: 10.1038/ncomms15867 | | |
| Ballistic superconductivity in semiconductor nanowires OPEN | | | Hao Zhang, Önder Gül, Sonia Conesa-Boj, Michał P. Nowak, Michael Wimmer, Kun Zuo, Vincent Mourik, Folkert K. de Vries, Jasper van Veen, Michiel W. A. de Moor, Jouri D. S. Bommer, David J. van Woerkom, Diana Car, Sébastien R Plissard, Erik P.A.M. Bakkers, Marina Quintero-Pérez, Maja C. Cassidy, Sebastian Koelling, Srijit Goswami, Kenji Watanabe et al. | | | Disorder has been a prime challenge to study the topological properties in a hybrid system. Here, Zhang et al. report ballistic superconductivity in InSb nanowires interfacing with a NbTiN superconductor, paving the way for disorder-free Majorana devices. | | | 06 July 2017 | doi: 10.1038/ncomms16025 | | |
| A defect in myoblast fusion underlies Carey-Fineman-Ziter syndrome OPEN | | | Silvio Alessandro Di Gioia, Samantha Connors, Norisada Matsunami, Jessica Cannavino, Matthew F. Rose, Nicole M. Gilette, Pietro Artoni, Nara Lygia de Macena Sobreira, Wai-Man Chan, Bryn D. Webb, Caroline D. Robson, Long Cheng, Carol Van Ryzin, Andres Ramirez-Martinez, Payam Mohassel, Mark Leppert, Mary Beth Scholand, Christopher Grunseich, Carlos R. Ferreira, Tyler Hartman et al. | | | During embryogenesis, the cytoplasmic protein Myomarker (MYMK) mediates muscle fibre formation by fusion of myoblasts. Here, the authors identify autosomal recessive mutations in MYMK that cause Carey-Fineman-Ziter syndrome in humans, and model the disease variants in zebrafish. | | | 06 July 2017 | doi: 10.1038/ncomms16077 | | |
| MIS-11 duration key to disappearance of the Greenland ice sheet OPEN | | | Alexander Robinson, Jorge Alvarez-Solas, Reinhard Calov, Andrey Ganopolski and Marisa Montoya | | | The most pronounced deglaciation of Greenland of the last several hundred thousand years occurred during Marine Isotope Stage 11. Here, the authors show that it was the exceptional duration of the interglacial period that allowed Greenland to melt even though temperatures were only moderately warmer than today. | | | 06 July 2017 | doi: 10.1038/ncomms16008 | | |
| Transparent flexible thermoelectric material based on non-toxic earth-abundant p-type copper iodide thin film OPEN | | | C. Yang, D. Souchay, M. Kneiß, M. Bogner, H. M. Wei, M. Lorenz, O. Oeckler, G. Benstetter, Y. Q. Fu and M. Grundmann | | | Flexible thermoelectric devices with high optical transparency may enable new applications; however, the lack of a p-type counterpart has hitherto hindered its development. Yang et al., report a transparent p-type thermoelectric based on polycrystalline copper iodide thin film with record performance. | | | 06 July 2017 | doi: 10.1038/ncomms16076 | | |
| Coordinated force generation of skeletal myosins in myofilaments through motor coupling OPEN | | | Motoshi Kaya, Yoshiaki Tani, Takumi Washio, Toshiaki Hisada and Hideo Higuchi | | | Skeletal muscle myosin forms large ensembles to generate force against high loads. Using optical tweezers and simulation Kaya et al. provide experimental evidence for cooperative force generation, and describe how the molecular properties of skeletal myosins are tuned for coordinated power strokes. | | | 06 July 2017 | doi: 10.1038/ncomms16036 | | |
| Quantized circular photogalvanic effect in Weyl semimetals OPEN | | | Fernando de Juan, Adolfo G. Grushin, Takahiro Morimoto and Joel E Moore | | | Photocurrent switches depend on circular polarization of the incident light. Here, De Juan et al. report a quantized circular photogalvanic effect as a measure of the topological charge of Weyl points in a class of Weyl semimetals and three-dimensional Rashba materials. | | | 06 July 2017 | doi: 10.1038/ncomms15995 | | |
| Combining photocatalytic hydrogen generation and capsule storage in graphene based sandwich structures OPEN | | | Li Yang, Xiyu Li, Guozhen Zhang, Peng Cui, Xijun Wang, Xiang Jiang, Jin Zhao, Yi Luo and Jun Jiang | | | Photocatalytic water splitting is an attractive route to hydrogen production, but safely isolating hydrogen and oxygen products remains a challenge. Here, the authors propose a carbon nitride/grapheme (GR)-based sandwich structure, providing safe and effective photocatalytic hydrogen generation and capsule storage. | | | 06 July 2017 | doi: 10.1038/ncomms16049 | | |
| The role of the 5f valence orbitals of early actinides in chemical bonding OPEN | | | T. Vitova, I. Pidchenko, D. Fellhauer, P. S. Bagus, Y. Joly, T. Pruessmann, S. Bahl, E. Gonzalez-Robles, J. Rothe, M. Altmaier, M. A. Denecke and H. Geckeis | | | Understanding the chemistry of heavy radioactive elements is crucial to harnessing them for fuel and medicine. Here, the authors combine advanced X-ray spectroscopy and modelling to the study the chemical bonding of the 5f valence orbitals of uranium, neptunium and plutonium. | | | 06 July 2017 | doi: 10.1038/ncomms16053 | | |
| Bacterial lipid droplets bind to DNA via an intermediary protein that enhances survival under stress OPEN | | | Congyan Zhang, Li Yang, Yunfeng Ding, Yang Wang, Lan Lan, Qin Ma, Xiang Chi, Peng Wei, Yongfang Zhao, Alexander Steinbüchel, Hong Zhang and Pingsheng Liu | | | The MLDS protein is a major component of lipid droplets (LDs) in oleaginous bacteria. Here, Zhang et al. show that LDs bind to genomic DNA via MLDS, which enhances bacterial survival under certain stress conditions. | | | 06 July 2017 | doi: 10.1038/ncomms15979 | | |
| YAP determines the cell fate of injured mouse hepatocytes in vivo OPEN | | | Norio Miyamura, Shoji Hata, Tohru Itoh, Minoru Tanaka, Miki Nishio, Michiko Itoh, Yoshihiro Ogawa, Shuji Terai, Isao Sakaida, Akira Suzuki, Atsushi Miyajima and Hiroshi Nishina | | | Senescent and injured cells affect tissue functions and can drive tumorigenesis. Thus, efficient elimination of these cells is pivotal for tissue integrity. Here Miyamura et al. show that YAP acts as a cellular stress sensor and promotes the elimination of damaged cells to maintain tissue homeostasis. | | | 06 July 2017 | doi: 10.1038/ncomms16017 | | |
| Marine viruses discovered via metagenomics shed light on viral strategies throughout the oceans OPEN | | | Felipe H. Coutinho, Cynthia B. Silveira, Gustavo B. Gregoracci, Cristiane C. Thompson, Robert A. Edwards, Corina P. D. Brussaard, Bas E. Dutilh and Fabiano L. Thompson | | | The understanding of marine virus diversity and function is in its infancy. Here, Coutinho et al. assemble a data set of new viral contigs and use co-occurrence analyses to identify the putative hosts, elucidate infection strategies and viral strategies for exploiting their hosts. | | | 05 July 2017 | doi: 10.1038/ncomms15955 | | |
| Enhancing a slow and weak optomechanical nonlinearity with delayed quantum feedback OPEN | | | Zhaoyou Wang and Amir H. Safavi-Naeini | | | Realization of photon-photon interaction is an interesting but challenging goal in photonics and quantum optics. Here the authors use a coherently delayed optomechanical platform with quantum feedback to generate the strong interaction between the single photons propagating in a waveguide. | | | 05 July 2017 | doi: 10.1038/ncomms15886 | | |
| Brain network dynamics in high-functioning individuals with autism OPEN | | | Takamitsu Watanabe and Geraint Rees | | | Though individuals with autism spectrum disorder (ASD) show a number of neural abnormalities, the relationship between global dynamic neural patterns and ASD symptoms remains unclear. Here, authors describe such global brain dynamics, relate these to cognitive abilities, ASD symptoms, and predict ASD diagnosis. | | | 05 July 2017 | doi: 10.1038/ncomms16048 | | |
| CTCF orchestrates the germinal centre transcriptional program and prevents premature plasma cell differentiation OPEN | | | Arantxa Pérez-García, Ester Marina-Zárate, Ángel F. Álvarez-Prado, Jose M. Ligos, Niels Galjart and Almudena R. Ramiro | | | Activated B cells differentiate into antibody-producing plasma cells in the germinal centre in secondary lymphoid organs. Here the authors show that this differentiation process and related transcription programs are modulated by the transcription factor CTCF, partly by suppressing the premature expression of Blimp-1. | | | 05 July 2017 | doi: 10.1038/ncomms16067 | | |
| Ballistic edge states in Bismuth nanowires revealed by SQUID interferometry OPEN | | | Anil Murani, Alik Kasumov, Shamashis Sengupta, Yu A. Kasumov, V. T. Volkov, I. I. Khodos, F. Brisset, Raphaëlle Delagrange, Alexei Chepelianskii, Richard Deblock, Hélène Bouchiat and Sophie Guéron | | | Demonstration of ballistic conduction and spin polarization of edge state currents in two dimensional topological insulators remains a challenge. Here, Murani et al. report a direct signature of ballistic one dimensional transport along the topological surfaces of a bismuth nanowire connected to superconducting electrodes. | | | 05 July 2017 | doi: 10.1038/ncomms15941 | | |
| SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits OPEN | | | Guillaume M. Hautbergue, Lydia M. Castelli, Laura Ferraiuolo, Alvaro Sanchez-Martinez, Johnathan Cooper-Knock, Adrian Higginbottom, Ya-Hui Lin, Claudia S. Bauer, Jennifer E. Dodd, Monika A. Myszczynska, Sarah M. Alam, Pierre Garneret, Jayanth S. Chandran, Evangelia Karyka, Matthew J. Stopford, Emma F. Smith, Janine Kirby, Kathrin Meyer, Brian K. Kaspar, Adrian M. Isaacs et al. | | | The RNA for ALS- and frontotemporal dementia-associated C9ORF72 gene is exported from nucleus via an unknown mechanism. This study shows that reduction of nuclear export adaptor SRSF1 can alleviate neuronal cell death and nuclear export of C9ORF72 in Drosophila and patient-derived induced motor neurons. | | | 05 July 2017 | doi: 10.1038/ncomms16063 | | |
| Electrical gate control of spin current in van der Waals heterostructures at room temperature OPEN | | | André Dankert and Saroj P. Dash | | | Two-dimensional materials are unique to build heterostructures with contrasting spintronic properties. Here, Dankert and Dash utilize a van der Waals heterostructure with graphene and MoS2 to demonstrate an all-electrical device for creation, transport and control of the spin current up to room temperature. | | | 05 July 2017 | doi: 10.1038/ncomms16093 | | | | | | | | | | | | | Latest Corrigendum | | | | | | | | | | | | Latest Errata | | | | |
| | | | | Erratum: ACF7 regulates inflammatory colitis and intestinal wound response by orchestrating tight junction dynamics OPEN | | | Yanlei Ma, Jiping Yue, Yao Zhang, Chenzhang Shi, Matt Odenwald, Wenguang G. Liang, Qing Wei, Ajay Goel, Xuewen Gou, Jamie Zhang, Shao-Yu Chen, Wei-Jen Tang, Jerrold R. Turner, Feng Yang, Hong Liang, Huanlong Qin and Xiaoyang Wu | | | 11 July 2017 | doi: 10.1038/ncomms16121 | | |
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