Immunology and Cell Biology - Table of Contents alert Volume 95 Issue 6

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Since microscopes were first invented, scientists have constantly been drawn to these marvellous machines. This is because microscopes provide their user with the ability to view first hand minuscule objects and processes they have often dedicated their entire careers to studying. It is this ability to view biology at work in both space and time, from a single molecule to an entire organism that makes imaging such a powerful tool. In this Special Feature, we have compiled a series of articles that discuss the history of microscopes and imaging modalities. We look at how current platforms have influenced basic research of immunology and cell biology as well as their use in the clinic to diagnose and treat disease. We also discuss how future developments in technology will open avenues for an even deeper understanding of fundamental principles in biology and the challenges associated with handling vast amounts of data generated by technology that gives such a high level of deta iled information. Immunology & Cell Biology thanks the coordinator of this Special Feature - Edwin Hawkins - for his planning and input. Please see articles marked TABLE OF CONTENTS Volume 95, Issue 6 (July 2017) In this issue News And Commentary Editorial Reviews Original Articles Short Communication Sign up for e-alerts Recommend to your library Web feed Subscribe News And Commentary Top Tumour vessel normalization and immune checkpoint blockade: a new synergism Ruth Ganss Immunol Cell Biol 2017 95: 497-498; advance online publication, May 23, 2017; 10.1038/icb.2017.30 Full Text Editorial Top Advanced microscopy and imaging techniques in immunology and cell biology   Edwin D Hawkins Immunol Cell Biol 2017 95: 499-500; 10.1038/icb.2017.34 Full Text | PDF Reviews Top In vitro tracking and intracellular protein distribution in immunology   Kajal Zibaei and Sarah M Russell Immunol Cell Biol 2017 95: 501-505; advance online publication, April 10, 2017; 10.1038/icb.2017.29 Abstract | Full Text Intravital microscopy in historic and contemporary immunology   Judith Secklehner, Cristina Lo Celso and Leo M Carlin Immunol Cell Biol 2017 95: 506-513; advance online publication, April 3, 2017; 10.1038/icb.2017.25 Abstract | Full Text Viewing immune regulation as it happens: in vivo imaging for investigation of regulatory T-cell function   Michael J Hickey and Zachary Chow Immunol Cell Biol 2017 95: 514-519; advance online publication, April 19, 2017; 10.1038/icb.2017.33 Abstract | Full Text The reinvention of twentieth century microscopy for three-dimensional imaging   Lachlan W Whitehead, Kate McArthur, Niall D Geoghegan and Kelly L Rogers Immunol Cell Biol 2017 95: 520-524; advance online publication, April 27, 2017; 10.1038/icb.2017.36 Abstract | Full Text Machine learning applications in cell image analysis   Andrey Kan Immunol Cell Biol 2017 95: 525-530; advance online publication, March 15, 2017; 10.1038/icb.2017.16 Abstract | Full Text Imaging to study solid tumour origin and progression: lessons from research and clinical oncology   Stefania Raimondo and Giovanni Zito Immunol Cell Biol 2017 95: 531-537; advance online publication, April 4, 2017; 10.1038/icb.2017.17 Abstract | Full Text Original Articles Top Myeloid-derived suppressor cells can be efficiently generated from human hematopoietic progenitors and peripheral blood monocytes Sílvia Casacuberta-Serra, Marta Parés, Arantxa Golbano, Elisabet Coves, Carmen Espejo and Jordi Barquinero Immunol Cell Biol 2017 95: 538-548; advance online publication, January 21, 2017; 10.1038/icb.2017.4 Abstract | Full Text Predominant contribution of DGKζ over DGKα in the control of PKC/PDK-1-regulated functions in T cells Antonia Ávila-Flores, Javier Arranz-Nicolás, Elena Andrada, Denise Soutar and Isabel Mérida Immunol Cell Biol 2017 95: 549-563; advance online publication, February 6, 2017; 10.1038/icb.2017.7 Abstract | Full Text Short Communication Top Development of SH2 probes and pull-down assays to detect pathogen-induced, site-specific tyrosine phosphorylation of the TLR adaptor SCIMP Lin Luo, Samuel J Tong, Adam A Wall, Tatiana Khromykh, Matthew J Sweet and Jennifer L Stow Immunol Cell Biol 2017 95: 564-570; advance online publication, March 14, 2017; 10.1038/icb.2017.10 Abstract | Full Text Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. 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