Monday, June 19, 2017

Nature Reviews Neuroscience contents July 2017 Volume 18 Number 7 pp 385-450

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Nature Reviews Neuroscience

Web collection: Parkinson disease 

2017 marks the 200th anniversary since James Parkinson published An Essay on the Shaking Palsy. To mark this event, Nature Reviews Disease Primers, Nature Reviews Neuroscience and Nature Reviews Neurology present this collection of articles about cutting-edge basic and clinical research into Parkinson disease. 

Take a look at the collection
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In this issue
Research Highlights

Also this month
 Featured article:
The sleep-deprived human brain
Adam J. Krause, Eti Ben Simon, Bryce A. Mander, Stephanie M. Greer, Jared M. Saletin, Andrea N. Goldstein-Piekarski & Matthew P. Walker


An open access journal dedicated to highlighting the most important scientific advances in Parkinson's disease research, spanning the motor and non-motor disorders of Parkinson's disease.

Part of the Nature Partner Journals series, npj Parkinson's Disease is published in partnership with the Parkinson's Disease Foundation. 

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Working memory: Persistence is key
p385 | doi:10.1038/nrn.2017.70
Three studies demonstrate that thalamocortical connections are necessary to maintain cortical delay activity in mice.


Neuron—glia interactions: Waking the synapse
p386 | doi:10.1038/nrn.2017.69
Wakefulness influences synaptic function in the hippocampus through the modulation of NMDA receptor co-agonist availability by astrocytes.


Learning and memory: When novel becomes familiar
p386 | doi:10.1038/nrn.2017.73
The transition from an odour being novel to being familiar in Drosophila Melanogaster involves dopaminergic modulation of the kenyon cell–α′3 mushroom body output neuron synapse in the fly mushroom body.



Sleep: Labelling sleep generators | Neurodevelopment: Organizing the second brain | Neural circuits: An angle on navigation | Neurodevelopmental disorders: Taking on FXS with a diabetes drug

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Functional consequences of neuropeptide and small-molecule co-transmission
Michael P. Nusbaum, Dawn M. Blitz & Eve Marder
p389 | doi:10.1038/nrn.2017.56
Small-molecule-neuropeptide co-transmission is pervasive throughout the nervous system of all animals. In this Review, Nusbaum, Blitz and Marder discuss how co-transmission is an important source for the considerable flexibility that has been established for synapses, circuits and behaviour.
Abstract | Full Text | PDF

The sleep-deprived human brain
Adam J. Krause, Eti Ben Simon, Bryce A. Mander, Stephanie M. Greer, Jared M. Saletin, Andrea N. Goldstein-Piekarski & Matthew P. Walker
p404 | doi:10.1038/nrn.2017.55
How does sleep deprivation affect the human brain? Walker and colleagues review neuroimaging studies on the consequences of sleep deprivation on cognition and emotion — with specific focuses on attention and working memory, positive and negative emotion, and hippocampal learning — and the mechanisms underlying these effects.
Abstract | Full Text | PDF

Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease
Kassandra Kisler, Amy R. Nelson, Axel Montagne & Berislav V. Zlokovic
p419 | doi:10.1038/nrn.2017.48
Cerebral blood flow regulation is essential for normal brain function. In this Review, Kisler and colleagues examine the cellular and molecular mechanisms that underlie cerebral blood flow regulation at the arteriole and capillary level, and how neurovascular dysfunction contributes to neurodegenerative disorders such as Alzheimer disease.
Abstract | Full Text | PDF

Non-motor features of Parkinson disease
Anthony H.V. Schapira, K. Ray Chaudhuri & Peter Jenner
p435 | doi:10.1038/nrn.2017.62
Parkinson disease is often characterized as a disorder of movement; however, it is also associated with many non-motor features, some of which appear early in the disease course. In this article, Schapira and colleagues provide an overview of these diverse features and their neurobiological basis.
Abstract | Full Text | PDF

Linking social context and addiction neuroscience: a computational psychiatry approach
Andrea Reiter, Andreas Heinz & Lorenz Deserno
p450 | doi:10.1038/nrn.2017.67
Full Text | PDF
Call for nominations: 2017 John Maddox Prize for Standing up for Science.

Recognising the work of individuals who promote science in the face of hostility. Winners will be announced at a reception in London, as well as in Nature, and will receive £2,000.

Closing date for nominations is 31st July 2017.

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