Special issue on Ubiquitin in Inflammation and Cell Death |
| | Inflammation and cell death are often accompanying processes during microbial infection and tissue maintenance, and their deregulation contributes to a wide range of pathologies, including immune disorders and cancer. The engagement of cytokine receptors and pattern recognition receptors that trigger inflammatory or anti-viral responses also stimulate cell death programmes under certain circumstances. Recently, it has become evident that these processes are closely connected and that the ubiquitin machinery is at the centre of the decision-making between inflammatory signalling, caspase-mediated apoptosis, and receptor-interacting protein kinase (RIPK)-mediated necroptosis. This special issue contains a series of state-of-the-art reviews by leading experts that collectively provide a comprehensive overview of the fascinating and still emerging ways by which ubiquitin intertwines with the cellular processes that control inflammation an d cell death. Please see articles marked | | TABLE OF CONTENTS
| | | | Volume 24, Issue 7 (July 2017) | | In this issue Editorial News And Commentary Perspectives Reviews Original Papers Correspondence Corrigenda
Also new AOP | | | | EDITORIAL | Top | | All roads lead to ubiquitinMads Gyrd-Hansen Cell Death Differ 2017 24: 1135-1136; 10.1038/cdd.2017.93 Full Text | PDF | NEWS AND COMMENTARIES | Top | | LACTB-mediated tumour suppression by increased mitochondrial lipid metabolismDanilo Cucchi and Claudio Mauro Cell Death Differ 2017 24: 1137-1139; advance online publication, May 5, 2017; 10.1038/cdd.2017.60 Full Text | Two paths to let the replisome go OPENVincenzo D'Angiolella and Daniele Guardavaccaro Cell Death Differ 2017 24: 1140-1141; advance online publication, May 19, 2017; 10.1038/cdd.2017.75 Full Text | PERSPECTIVES | Top | | SPATA2: more than a missing linkLisa Schlicher, Prisca Brauns-Schubert, Florian Schubert and Ulrich Maurer Cell Death Differ 2017 24: 1142-1147; advance online publication, March 10, 2017; 10.1038/cdd.2017.26 Abstract | Full Text | The making of a mammalian peroxisome, version 2.0: mitochondria get into the mixMichael Schrader and Luca Pellegrini Cell Death Differ 2017 24: 1148-1152; advance online publication, April 14, 2017; 10.1038/cdd.2017.23 Abstract | Full Text | REVIEWS | Top | | The role of hybrid ubiquitin chains in the MyD88 and other innate immune signalling pathways OPENPhilip Cohen and Sam Strickson Cell Death Differ 2017 24: 1153-1159; advance online publication, May 5, 2017; 10.1038/cdd.2017.17 Abstract | Full Text | Diverse ubiquitin linkages regulate RIP kinases-mediated inflammatory and cell death signalingAxel Witt and Domagoj Vucic Cell Death Differ 2017 24: 1160-1171; advance online publication, May 5, 2017; 10.1038/cdd.2017.33 Abstract | Full Text | CYLD, A20 and OTULIN deubiquitinases in NF-κB signaling and cell death: so similar, yet so differentMarie Lork, Kelly Verhelst and Rudi Beyaert Cell Death Differ 2017 24: 1172-1183; advance online publication, March 31, 2017; 10.1038/cdd.2017.46 Abstract | Full Text | Initiation and execution mechanisms of necroptosis: an overviewSasker Grootjans, Tom Vanden Berghe and Peter Vandenabeele Cell Death Differ 2017 24: 1184-1195; advance online publication, May 12, 2017; 10.1038/cdd.2017.65 Abstract | Full Text | The small molecule that packs a punch: ubiquitin-mediated regulation of RIPK1/FADD/caspase-8 complexesRebecca Feltham and John Silke Cell Death Differ 2017 24: 1196-1204; advance online publication, June 2, 2017; 10.1038/cdd.2017.67 Abstract | Full Text | ORIGINAL PAPERS | Top | | miR-199a impairs autophagy and induces cardiac hypertrophy through mTOR activation OPENZ Li, Y Song, L Liu, N Hou, X An, D Zhan, Y Li, L Zhou, P Li, L Yu, J Xia, Y Zhang, J Wang and X Yang Cell Death Differ 2017 24: 1205-1213; advance online publication, July 10, 2015; 10.1038/cdd.2015.95 Abstract | Full Text | MALT1 is an intrinsic regulator of regulatory T cells OPENA Brüstle, D Brenner, C B Knobbe-Thomsen, M Cox, P A Lang, K S Lang and T W Mak Cell Death Differ 2017 24: 1214-1223; advance online publication, September 25, 2015; 10.1038/cdd.2015.104 Abstract | Full Text | Mesenchymal stem cells sense mitochondria released from damaged cells as danger signals to activate their rescue properties OPENMeriem Mahrouf-Yorgov, Lionel Augeul, Claire Crola Da Silva, Maud Jourdan, Muriel Rigolet, Sylvie Manin, René Ferrera, Michel Ovize, Adeline Henry, Aurélie Guguin, Jean-Paul Meningaud, Jean-Luc Dubois-Randé, Roberto Motterlini, Roberta Foresti and Anne-Marie Rodriguez Cell Death Differ 2017 24: 1224-1238; advance online publication, May 19, 2017; 10.1038/cdd.2017.51 Abstract | Full Text | A defined metabolic state in pre B cells governs B-cell development and is counterbalanced by Swiprosin-2/EFhd1Merle Stein, Sebastian Dütting, Dimitrios Mougiakakos, Michael Bösl, Kristin Fritsch, Dorothea Reimer, Sophia Urbanczyk, Tobit Steinmetz, Wolfgang Schuh, Aline Bozec, Thomas H Winkler, Hans-Martin Jäck and Dirk Mielenz Cell Death Differ 2017 24: 1239-1252; advance online publication, May 19, 2017; 10.1038/cdd.2017.52 Abstract | Full Text | MicroRNA-30a attenuates mutant KRAS-driven colorectal tumorigenesis via direct suppression of ME1Hongxing Shen, Chuan Xing, Kaisa Cui, Yunxiao Li, Jinxiang Zhang, Runlei Du, Xiaodong Zhang and Youjun Li Cell Death Differ 2017 24: 1253-1262; advance online publication, May 5, 2017; 10.1038/cdd.2017.63 Abstract | Full Text | A novel microRNA regulator of prostate cancer epithelial–mesenchymal transitionNathan Bucay, Divya Bhagirath, Kirandeep Sekhon, Thao Yang, Shinichiro Fukuhara, Shahana Majid, Varahram Shahryari, ZLaura Tabatabai, Kirsten L Greene, Yutaka Hashimoto, Marisa Shiina, Soichiro Yamamura, Yuichiro Tanaka, Guoren Deng, Rajvir Dahiya and Sharanjot Saini Cell Death Differ 2017 24: 1263-1274; advance online publication, May 12, 2017; 10.1038/cdd.2017.69 Abstract | Full Text | Inhibition of Twist1-mediated invasion by Chk2 promotes premature senescence in p53-defective cancer cellsDebasis Nayak, Anmol Kumar, Souneek Chakraborty, Reyaz ur Rasool, Hina Amin, Archana Katoch, Veena Gopinath, Vidushi Mahajan, Mahesh K Zilla, Bilal Rah, Sumit G Gandhi, Asif Ali, Lekha Dinesh Kumar and Anindya Goswami Cell Death Differ 2017 24: 1275-1287; advance online publication, May 12, 2017; 10.1038/cdd.2017.70 Abstract | Full Text | Signalome-wide RNAi screen identifies GBA1 as a positive mediator of autophagic cell death OPENSantosh K Dasari, Shani Bialik, Smadar Levin-Zaidman, Vered Levin-Salomon, Alfred H Merrill, Jr, Anthony H Futerman and Adi Kimchi Cell Death Differ 2017 24: 1288-1302; advance online publication, June 2, 2017; 10.1038/cdd.2017.80 Abstract | Full Text | CORRESPONDENCE | Top | | PTEN deficiency permits the formation of pancreatic cancer in the absence of autophagy OPENMathias T Rosenfeldt, Jim O'Prey, Lucia Flossbach, Colin Nixon, Jennifer P Morton, Owen J Sansom and Kevin M Ryan Cell Death Differ 2017 24: 1303-1304; advance online publication, January 20, 2017; 10.1038/cdd.2016.120 Full Text | CORRIGENDA | Top | | A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTRA Tosco, F De Gregorio, S Esposito, D De Stefano, I Sana, E Ferrari, A Sepe, L Salvadori, P Buonpensiero, A Di Pasqua, R Grassia, C A Leone, S Guido, G De Rosa, S Lusa, G Bona, G Stoll, M C Maiuri, A Mehta, G Kroemer, L Maiuri and V Raia Cell Death Differ 2017 24: 1305; advance online publication, July 22, 2016; 10.1038/cdd.2016.43 Full Text | An RNA interference screen identifies new avenues for nephroprotectionE R Zynda, B Schott, S Gruener, E Wernher, G D Nguyen, M Ebeling and E S Kandel Cell Death Differ 2017 24: 1306; advance online publication, November 18, 2016; 10.1038/cdd.2016.98 Full Text | | | | | | | | | | Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. 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