Monday, June 26, 2017

Cell Death and Differentiation - Table of Contents alert Volume 24 Issue 7

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Cell Death and Differentiation

Special issue on Ubiquitin in Inflammation and Cell Death

Inflammation and cell death are often accompanying processes during microbial infection and tissue maintenance, and their deregulation contributes to a wide range of pathologies, including immune disorders and cancer. The engagement of cytokine receptors and pattern recognition receptors that trigger inflammatory or anti-viral responses also stimulate cell death programmes under certain circumstances. Recently, it has become evident that these processes are closely connected and that the ubiquitin machinery is at the centre of the decision-making between inflammatory signalling, caspase-mediated apoptosis, and receptor-interacting protein kinase (RIPK)-mediated necroptosis. This special issue contains a series of state-of-the-art reviews by leading experts that collectively provide a comprehensive overview of the fascinating and still emerging ways by which ubiquitin intertwines with the cellular processes that control inflammation an d cell death.

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Volume 24, Issue 7 (July 2017)

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News And Commentary
Original Papers

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All roads lead to ubiquitin

Mads Gyrd-Hansen

Cell Death Differ 2017 24: 1135-1136; 10.1038/cdd.2017.93

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LACTB-mediated tumour suppression by increased mitochondrial lipid metabolism

Danilo Cucchi and Claudio Mauro

Cell Death Differ 2017 24: 1137-1139; advance online publication, May 5, 2017; 10.1038/cdd.2017.60

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Two paths to let the replisome go OPEN

Vincenzo D'Angiolella and Daniele Guardavaccaro

Cell Death Differ 2017 24: 1140-1141; advance online publication, May 19, 2017; 10.1038/cdd.2017.75

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SPATA2: more than a missing link

Lisa Schlicher, Prisca Brauns-Schubert, Florian Schubert and Ulrich Maurer

Cell Death Differ 2017 24: 1142-1147; advance online publication, March 10, 2017; 10.1038/cdd.2017.26

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The making of a mammalian peroxisome, version 2.0: mitochondria get into the mix

Michael Schrader and Luca Pellegrini

Cell Death Differ 2017 24: 1148-1152; advance online publication, April 14, 2017; 10.1038/cdd.2017.23

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The role of hybrid ubiquitin chains in the MyD88 and other innate immune signalling pathways OPEN

Philip Cohen and Sam Strickson

Cell Death Differ 2017 24: 1153-1159; advance online publication, May 5, 2017; 10.1038/cdd.2017.17

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Diverse ubiquitin linkages regulate RIP kinases-mediated inflammatory and cell death signaling

Axel Witt and Domagoj Vucic

Cell Death Differ 2017 24: 1160-1171; advance online publication, May 5, 2017; 10.1038/cdd.2017.33

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CYLD, A20 and OTULIN deubiquitinases in NF-κB signaling and cell death: so similar, yet so different

Marie Lork, Kelly Verhelst and Rudi Beyaert

Cell Death Differ 2017 24: 1172-1183; advance online publication, March 31, 2017; 10.1038/cdd.2017.46

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Initiation and execution mechanisms of necroptosis: an overview

Sasker Grootjans, Tom Vanden Berghe and Peter Vandenabeele

Cell Death Differ 2017 24: 1184-1195; advance online publication, May 12, 2017; 10.1038/cdd.2017.65

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The small molecule that packs a punch: ubiquitin-mediated regulation of RIPK1/FADD/caspase-8 complexes

Rebecca Feltham and John Silke

Cell Death Differ 2017 24: 1196-1204; advance online publication, June 2, 2017; 10.1038/cdd.2017.67

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miR-199a impairs autophagy and induces cardiac hypertrophy through mTOR activation OPEN

Z Li, Y Song, L Liu, N Hou, X An, D Zhan, Y Li, L Zhou, P Li, L Yu, J Xia, Y Zhang, J Wang and X Yang

Cell Death Differ 2017 24: 1205-1213; advance online publication, July 10, 2015; 10.1038/cdd.2015.95

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MALT1 is an intrinsic regulator of regulatory T cells OPEN

A Brüstle, D Brenner, C B Knobbe-Thomsen, M Cox, P A Lang, K S Lang and T W Mak

Cell Death Differ 2017 24: 1214-1223; advance online publication, September 25, 2015; 10.1038/cdd.2015.104

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Mesenchymal stem cells sense mitochondria released from damaged cells as danger signals to activate their rescue properties OPEN

Meriem Mahrouf-Yorgov, Lionel Augeul, Claire Crola Da Silva, Maud Jourdan, Muriel Rigolet, Sylvie Manin, René Ferrera, Michel Ovize, Adeline Henry, Aurélie Guguin, Jean-Paul Meningaud, Jean-Luc Dubois-Randé, Roberto Motterlini, Roberta Foresti and Anne-Marie Rodriguez

Cell Death Differ 2017 24: 1224-1238; advance online publication, May 19, 2017; 10.1038/cdd.2017.51

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A defined metabolic state in pre B cells governs B-cell development and is counterbalanced by Swiprosin-2/EFhd1

Merle Stein, Sebastian Dütting, Dimitrios Mougiakakos, Michael Bösl, Kristin Fritsch, Dorothea Reimer, Sophia Urbanczyk, Tobit Steinmetz, Wolfgang Schuh, Aline Bozec, Thomas H Winkler, Hans-Martin Jäck and Dirk Mielenz

Cell Death Differ 2017 24: 1239-1252; advance online publication, May 19, 2017; 10.1038/cdd.2017.52

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MicroRNA-30a attenuates mutant KRAS-driven colorectal tumorigenesis via direct suppression of ME1

Hongxing Shen, Chuan Xing, Kaisa Cui, Yunxiao Li, Jinxiang Zhang, Runlei Du, Xiaodong Zhang and Youjun Li

Cell Death Differ 2017 24: 1253-1262; advance online publication, May 5, 2017; 10.1038/cdd.2017.63

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A novel microRNA regulator of prostate cancer epithelial–mesenchymal transition

Nathan Bucay, Divya Bhagirath, Kirandeep Sekhon, Thao Yang, Shinichiro Fukuhara, Shahana Majid, Varahram Shahryari, ZLaura Tabatabai, Kirsten L Greene, Yutaka Hashimoto, Marisa Shiina, Soichiro Yamamura, Yuichiro Tanaka, Guoren Deng, Rajvir Dahiya and Sharanjot Saini

Cell Death Differ 2017 24: 1263-1274; advance online publication, May 12, 2017; 10.1038/cdd.2017.69

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Inhibition of Twist1-mediated invasion by Chk2 promotes premature senescence in p53-defective cancer cells

Debasis Nayak, Anmol Kumar, Souneek Chakraborty, Reyaz ur Rasool, Hina Amin, Archana Katoch, Veena Gopinath, Vidushi Mahajan, Mahesh K Zilla, Bilal Rah, Sumit G Gandhi, Asif Ali, Lekha Dinesh Kumar and Anindya Goswami

Cell Death Differ 2017 24: 1275-1287; advance online publication, May 12, 2017; 10.1038/cdd.2017.70

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Signalome-wide RNAi screen identifies GBA1 as a positive mediator of autophagic cell death OPEN

Santosh K Dasari, Shani Bialik, Smadar Levin-Zaidman, Vered Levin-Salomon, Alfred H Merrill, Jr, Anthony H Futerman and Adi Kimchi

Cell Death Differ 2017 24: 1288-1302; advance online publication, June 2, 2017; 10.1038/cdd.2017.80

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PTEN deficiency permits the formation of pancreatic cancer in the absence of autophagy OPEN

Mathias T Rosenfeldt, Jim O'Prey, Lucia Flossbach, Colin Nixon, Jennifer P Morton, Owen J Sansom and Kevin M Ryan

Cell Death Differ 2017 24: 1303-1304; advance online publication, January 20, 2017; 10.1038/cdd.2016.120

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A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR

A Tosco, F De Gregorio, S Esposito, D De Stefano, I Sana, E Ferrari, A Sepe, L Salvadori, P Buonpensiero, A Di Pasqua, R Grassia, C A Leone, S Guido, G De Rosa, S Lusa, G Bona, G Stoll, M C Maiuri, A Mehta, G Kroemer, L Maiuri and V Raia

Cell Death Differ 2017 24: 1305; advance online publication, July 22, 2016; 10.1038/cdd.2016.43

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An RNA interference screen identifies new avenues for nephroprotection

E R Zynda, B Schott, S Gruener, E Wernher, G D Nguyen, M Ebeling and E S Kandel

Cell Death Differ 2017 24: 1306; advance online publication, November 18, 2016; 10.1038/cdd.2016.98

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