Nature Reviews Microbiology contents June 2017 Volume 15 Number 6 pp 319-379

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TABLE OF CONTENTS
June 2017 Volume 15 Number 6
2015 2-year Impact Factor 24.727 Journal Metrics 2-year Median 19.5	In this issue Research Highlights News and Analysis Reviews Also this month Article series: New technologies: methods and applications  Featured article: Assembly, structure, function and regulation of type III secretion systems Wanyin Deng, Natalie C. Marshall, Jennifer L. Rowland, James M. McCoy, Liam J. Worrall, Andrew S. Santos, Natalie C. J. Strynadka & B. Brett Finlay
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RESEARCH HIGHLIGHTS Top Bacterial physiology: Shuttling lipids across bacterial membranes p319 | doi:10.1038/nrmicro.2017.49 Two recent studies provide novel mechanistic and structural insights into lipid and lipoprotein transport between the inner and outer bacterial membranes, across the periplasmic space. PDF Biofilms: Communities in sync p320 | doi:10.1038/nrmicro.2017.46 This study shows that distant biofilms can coordinate their behaviour and use time-sharing to increase their growth rate under nutrient-limiting conditions PDF Parasite development: Plasmodium breaks the linkage p320 | doi:10.1038/nrmicro.2017.48 Burda et al. found that Plasmodium berghei liver-stage merozoites induce the disruption of the actin-plasma membrane linkage, which might promote merosome formation. PDF Viral pathogenesis: Masked by macrophages p320 | doi:10.1038/nrmicro.2017.52 This study provides experimental support that macrophages may represent a persistent viral reservoir for HIV-1 in vivo. PDF IN BRIEF Bacterial physiology: Hsp90 is the hot guy for Shewanella oneidensis | Microbiota: Clostridia protect from gut infections in early life | Biofilms: New ways for streptococci to settle down PDF Nature Reviews Microbiology JOBS of the week Postdoc researcher microbiology In Ovo Postdoctoral Associate University of South Florida Health Microbial genomics expert University Hospital Basel Scientist in Human Microbiome Nestlé Research Center (NRC) Postdoc Position Max-Planck-Institute for Infection Biology More Science jobs from Nature Reviews Microbiology EVENT The International Conference on Microbiology, Virology and Immunology (CMVI 2017) 01.12.17 Sanya, China More science events from
NEWS AND ANALYSIS		Top
GENOME WATCH Reshaping the tree of life Eva Heinz & Daryl Domman p322 | doi:10.1038/nrmicro.2017.51 This month's Genome Watch highlights how metagenomics is continuing to reveal the diversity of microorganisms in the environment and how it is challenging and expanding our understanding of how life evolved on Earth. PDF
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REVIEWS		Top
Assembly, structure, function and regulation of type III secretion systems Wanyin Deng, Natalie C. Marshall, Jennifer L. Rowland, James M. McCoy, Liam J. Worrall, Andrew S. Santos, Natalie C. J. Strynadka & B. Brett Finlay p323 | doi:10.1038/nrmicro.2017.20 Type III secretion systems (T3SSs) are protein transport nanomachines that resemble molecular syringes and are found in numerous Gram-negative bacterial species. This Review summarizes our current understanding of the structure and function of these important protein secretion systems, incorporating new advances from cryo-electron microscopy and integrative imaging studies. Abstract | Full Text | PDF
Metal homeostasis and resistance in bacteria Pete Chandrangsu, Christopher Rensing & John D. Helmann p338 | doi:10.1038/nrmicro.2017.15 In this Review, Chandrangsu et al. discuss recent insights into metalloregulatory systems that are used by bacteria and how they respond to metal limitation and intoxication, as well as how these systems influence host-pathogen interactions. Abstract | Full Text | PDF
Article series: New technologies: methods and applications A CRISPR toolbox to study virus-host interactions Andreas S. Puschnik, Karim Majzoub, Yaw Shin Ooi & Jan E. Carette p351 | doi:10.1038/nrmicro.2017.29 In this Review, Puschnik and colleagues discuss the technical aspects of using CRISPR-Cas technology in genome-scale knockout screens to study virus-host interactions, and they compare these screens with alternative genetic screening technologies. Abstract | Full Text | PDF
A comprehensive guide to pilus biogenesis in Gram-negative bacteria Manuela K. Hospenthal, Tiago R. D. Costa & Gabriel Waksman p365 | doi:10.1038/nrmicro.2017.40 Pili are crucial virulence factors in many Gram-negative pathogens; these surface structures enable bacteria to interact with, and attach to structures in, their environment and can also facilitate horizontal gene transfer. In this Review, Waksman et al. examine recent advances in our structural understanding of various pilus systems in Gram-negative bacteria and discuss their functional implications. Abstract | Full Text | PDF
Corrigendum: Metal homeostasis and resistance in bacteria Pete Chandrangsu, Christopher Rensing & John D. Helmann p379 | doi:10.1038/nrmicro.2017.53 Full Text | PDF
Corrigendum: Assembly, structure, function and regulation of type III secretion systems Wanyin Deng, Natalie C. Marshall, Jennifer L. Rowland, James M. McCoy, Liam J. Worrall, Andrew S. Santos, Natalie C. J. Strynadka & B. Brett Finlay p379 | doi:10.1038/nrmicro.2017.54 Full Text | PDF
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