Wednesday, May 10, 2017

British Journal of Cancer - Table of Contents alert Volume 116 Issue 10

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British Journal of Cancer


Volume 116, Issue 10 (1247-1373)
Published online 9 May 2017

In this issue
Clinical Studies
Translational Therapeutics
Molecular Diagnostics

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Clinical Studies


Quality-adjusted survival with combination nal-IRI+5-FU/LV vs 5-FU/LV alone in metastatic pancreatic cancer patients previously treated with gemcitabine-based therapy: a Q-TWiST analysis

Uwe Pelzer, Jean-Frédéric Blanc, Davide Melisi, Antonio Cubillo, Daniel D Von Hoff, Andrea Wang-Gillam, Li-Tzong Chen, Jens T Siveke, Yin Wan, Caitlyn T Solem, Marc F Botteman, Yoojung Yang, Floris A de Jong and Richard A Hubner

Br J Cancer 2017 116: 1247-1253; advance online publication, March 28, 2017; 10.1038/bjc.2017.67

Abstract | Full Text

Evaluating wait times from screening to breast cancer diagnosis among women undergoing organised assessment vs usual care

Anna M Chiarelli, Derek Muradali, Kristina M Blackmore, Courtney R Smith, Lucia Mirea, Vicky Majpruz, Frances P O'Malley, May Lynn Quan and Claire MB Holloway

Br J Cancer 2017 116: 1254-1263; advance online publication, March 30, 2017; 10.1038/bjc.2017.87

Abstract | Full Text

Long-term results and recurrence patterns from SCALOP: a phase II randomised trial of gemcitabine- or capecitabine-based chemoradiation for locally advanced pancreatic cancer

C N Hurt, S Falk, T Crosby, A McDonald, R Ray, G Joseph, J Staffurth, R A Abrams, G Griffiths, T Maughan and S Mukherjee

Br J Cancer 2017 116: 1264-1270; advance online publication, April 4, 2017; 10.1038/bjc.2017.95

Abstract | Full Text

Cetuximab in treatment of metastatic colorectal cancer: final survival analyses and extended RAS data from the NORDIC-VII study

Tormod Kyrre Guren, Maria Thomsen, Elin H Kure, Halfdan Sorbye, Bengt Glimelius, Per Pfeiffer, Pia Österlund, Fridbjörn Sigurdsson, Inger Marie Bowitz Lothe, Astrid Marie Dalsgaard, Eva Skovlund, Thoralf Christoffersen and Kjell Magne Tveit

Br J Cancer 2017 116: 1271-1278; advance online publication, April 11, 2017; 10.1038/bjc.2017.93

Abstract | Full Text

A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation

M A Calegari, A Inno, S Monterisi, A Orlandi, D Santini, M Basso, A Cassano, M Martini, T Cenci, I de Pascalis, F Camarda, B Barbaro, L M Larocca, S Gori, G Tonini and C Barone

Br J Cancer 2017 116: 1279-1286; advance online publication, April 20, 2017; 10.1038/bjc.2017.109

Abstract | Full Text

Translational Therapeutics


Methylation of MYLK3 gene promoter region: a biomarker to stratify surgical care in ovarian cancer in a multicentre study

David L Phelps, Jane V Borley, Kirsty J Flower, Roberto Dina, Silvia Darb-Esfahani, Ioana Braicu, Jalid Sehouli, Christina Fotopoulou, Charlotte S Wilhelm-Benartzi, Hani Gabra, Joseph Yazbek, Jayanta Chatterjee, Jacey Ip, Harun Khan, Marina-Therese Likos-Corbett, Robert Brown and Sadaf Ghaem-Maghami

Br J Cancer 2017 116: 1287-1293; advance online publication, March 28, 2017; 10.1038/bjc.2017.83

Abstract | Full Text

Safety and utility of image-guided research biopsies in relapsed high-grade serous ovarian carcinoma—experience of the BriTROC consortium

T Goranova, D Ennis, A M Piskorz, G Macintyre, L A Lewsley, J Stobo, C Wilson, D Kay, R M Glasspool, M Lockley, E Brockbank, A Montes, A Walther, S Sundar, R Edmondson, G D Hall, A Clamp, C Gourley, M Hall, C Fotopoulou, H Gabra, S Freeman, L Moore, M Jimenez-Linan, J Paul, J D Brenton and I A McNeish on behalf of the BriTROC investigators18

Br J Cancer 2017 116: 1294-1301; advance online publication, March 30, 2017; 10.1038/bjc.2017.86

Abstract | Full Text

Lithium enhances the antitumour effect of temozolomide against TP53 wild-type glioblastoma cells via NFAT1/FasL signalling

Sheng Han, Lingxuan Meng, Yang Jiang, Wen Cheng, Xinxin Tie, Junzhe Xia and Anhua Wu

Br J Cancer 2017 116: 1302-1311; advance online publication, March 30, 2017; 10.1038/bjc.2017.89

Abstract | Full Text

Towards better dose individualisation: metabolic phenotyping to predict cabazitaxel pharmacokinetics in men with prostate cancer

A Janssen, C P M Verkleij, A van der Vlist, R H J Mathijssen, H J Bloemendal and R ter Heine

Br J Cancer 2017 116: 1312-1317; advance online publication, April 11, 2017; 10.1038/bjc.2017.91

Abstract | Full Text

Decreased levels of baseline and drug-induced tubulin polymerisation are hallmarks of resistance to taxanes in ovarian cancer cells and are associated with epithelial-to-mesenchymal transition

George E Duran, Yan C Wang, François Moisan, E Brian Francisco and Branimir I Sikic

Br J Cancer 2017 116: 1318-1328; advance online publication, April 11, 2017; 10.1038/bjc.2017.102

Abstract | Full Text

Predicting breast cancer response to neoadjuvant chemotherapy using pretreatment diffuse optical spectroscopic texture analysis

William T Tran, Mehrdad J Gangeh, Lakshmanan Sannachi, Lee Chin, Elyse Watkins, Silvio G Bruni, Rashin Fallah Rastegar, Belinda Curpen, Maureen Trudeau, Sonal Gandhi, Martin Yaffe, Elzbieta Slodkowska, Charmaine Childs, Ali Sadeghi-Naini and Gregory J Czarnota

Br J Cancer 2017 116: 1329-1339; advance online publication, April 18, 2017; 10.1038/bjc.2017.97

Abstract | Full Text

Differential pattern of HIF-1α expression in HNSCC cancer stem cells after carbon ion or photon irradiation: one molecular explanation of the oxygen effect

Anne-Sophie Wozny, Alexandra Lauret, Priscillia Battiston-Montagne, Jean-Baptiste Guy, Michael Beuve, Micaela Cunha, Yannick Saintigny, Emilie Blond, Nicolas Magne, Philippe Lalle, Dominique Ardail, Gersende Alphonse and Claire Rodriguez-Lafrasse

Br J Cancer 2017 116: 1340-1349; advance online publication, April 13, 2017; 10.1038/bjc.2017.100

Abstract | Full Text

Molecular Diagnostics


Targeting of CCBE1 by miR-330-3p in human breast cancer promotes metastasis

Aruz Mesci, Xiaoyong Huang, Samira Taeb, Sahar Jahangiri, Yohan Kim, Emmanouil Fokas, Jeff Bruce, Hon S Leong and Stanley K Liu

Br J Cancer 2017 116: 1350-1357; advance online publication, April 18, 2017; 10.1038/bjc.2017.105

Abstract | Full Text



Serum inflammatory markers and colorectal cancer risk and survival

Sundeep Ghuman, Mieke Van Hemelrijck, Hans Garmo, Lars Holmberg, Håkan Malmström, Mats Lambe, Niklas Hammar, Göran Walldius, Ingmar Jungner and Wahyu Wulaningsih

Br J Cancer 2017 116: 1358-1365; advance online publication, April 4, 2017; 10.1038/bjc.2017.96

Abstract | Full Text

Tyrosine kinase-targeting drugs-associated heart failure

N Gronich, I Lavi, O Barnett-Griness, W Saliba, D R Abernethy and G Rennert

Br J Cancer 2017 116: 1366-1373; advance online publication, April 11, 2017; 10.1038/bjc.2017.88

Abstract | Full Text

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