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May 2017 Volume 17 Number 5 | Advertisement | |||||||||||||||||||||||||||||||||||||||
In this issue Research Highlights Reviews Correction
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REVIEWS | Top | |||||||||||||||||||||||||||||||||||||||
Microbiota: a key orchestrator of cancer therapy Soumen Roy & Giorgio Trinchieri p271 | doi:10.1038/nrc.2017.13 The human microbiota influences a whole range of physiological functions. In this Review, Roy and Trinchieri discuss our current understanding of how the gut microbiota modulates responses to cancer therapy as well as mediating susceptibility to toxic side effects. Abstract | Full Text | PDF | ||||||||||||||||||||||||||||||||||||||||
Prospects for combining targeted and conventional cancer therapy with immunotherapy Philip Gotwals et al. p286 | doi:10.1038/nrc.2017.17 Insights into the effects of targeted therapies, conventional chemotherapy and radiation therapy, on the induction of antitumour immunity will help to advance the design of combination strategies that increase the rate of complete and durable clinical responses in patients. Abstract | Full Text | PDF | ||||||||||||||||||||||||||||||||||||||||
Pre-metastatic niches: organ-specific homes for metastases Héctor Peinado et al. p302 | doi:10.1038/nrc.2017.6 This Review summarizes the natural progression of pre-metastatic niche formation and evolution, highlighting recent advances and future hurdles. Abstract | Full Text | PDF | ||||||||||||||||||||||||||||||||||||||||
Advances and challenges in targeting FGFR signalling in cancer Irina S. Babina & Nicholas C. Turner p318 | doi:10.1038/nrc.2017.8 Deregulation of fibroblast growth factor (FGF) signalling is observed in several types of cancer, which makes this pathway a highly promising potential therapeutic target. However, aberrant FGF receptor (FGFR) signalling can be challenging. In this Review, Babina et al. discuss the differences between diverse mechanisms of oncogenic activation of FGFR, and the factors that determine response and resistance to FGFR targeting. Abstract | Full Text | PDF | ||||||||||||||||||||||||||||||||||||||||
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Leukaemia: 'Gimme shelter' Nicola McCarthy p332 | doi:10.1038/nrc.2017.14 Full Text | PDF | ||||||||||||||||||||||||||||||||||||||||
Corrigendum: New frontiers in translational control of the cancer genome Morgan L. Truitt & Davide Ruggero p332 | doi:10.1038/nrc.2017.30 Full Text | PDF | ||||||||||||||||||||||||||||||||||||||||
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