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Visit our open access funding page or contact openaccess@nature.com to learn more about APC funding. | | | | Latest Articles | View all Articles | | | Exercise contagion in a global social network OPEN | | Sinan Aral and Christos Nicolaides | | Some argue that health-related behaviours, such as obesity, are contagious, but empirical evidence of health contagion remains inconclusive. Here, using a large scale quasi-experiment in a global network of runners, Aral and Nicolaides show that this type of contagion exists in fitness behaviours. | | 18 April 2017 | doi: 10.1038/ncomms14753 | | | Large near-term projected snowpack loss over the western United States OPEN | | John C. Fyfe, Chris Derksen, Lawrence Mudryk, Gregory M. Flato, Benjamin D. Santer, Neil C. Swart, Noah P. Molotch, Xuebin Zhang, Hui Wan, Vivek K. Arora, John Scinocca and Yanjun Jiao | | Mountain snowpack in the western United States has declined over the past three decades. Fyfe et al. show that this trend cannot be explained by natural variability alone and show that under a business-as-usual scenario a further loss of up to 60% in mountain snowpack is projected in the coming three decades. | | 18 April 2017 | doi: 10.1038/ncomms14996 | | | Cumulative culture can emerge from collective intelligence in animal groups OPEN | | Takao Sasaki and Dora Biro | | Groups of animals tend to solve tasks better than individuals, but it is unclear whether such socially-derived knowledge accumulates over time. Sasaki and Biro demonstrate that homing pigeon flocks progressively improve the efficiency of their routes by culturally accumulating knowledge across generations. | | 18 April 2017 | doi: 10.1038/ncomms15049 | | | A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling OPEN | | Alexandre Beautrait, Justine S. Paradis, Brandon Zimmerman, Jenna Giubilaro, Ljiljana Nikolajev, Sylvain Armando, Hiroyuki Kobayashi, Lama Yamani, Yoon Namkung, Franziska M. Heydenreich, Etienne Khoury, Martin Audet, Philippe P. Roux, Dmitry B. Veprintsev, Stéphane A. Laporte and Michel Bouvier | | Beta-arrestins play central roles in the mechanisms regulating GPCR signalling and trafficking. Here the authors identify a selective inhibitor of the interaction between β-arrestin and the β2-adaptin subunit of the clathrin adaptor protein AP-2, which they use to dissect the role of the β-arrestin/β2-adaptin interaction in GPCR signalling. | | 18 April 2017 | doi: 10.1038/ncomms15054 | | | Unification of de novo and acquired ibrutinib resistance in mantle cell lymphoma OPEN | | Xiaohong Zhao, Tint Lwin, Ariosto Silva, Bijal Shah, Jiangchuan Tao, Bin Fang, Liang Zhang, Kai Fu, Chengfeng Bi, Jiannong Li, Huijuan Jiang, Mark B. Meads, Timothy Jacobson, Maria Silva, Allison Distler, Lancia Darville, Ling Zhang, Ying Han, Dmitri Rebatchouk, Maurizio Di Liberto et al. | | Ibrutinib has demonstrated high response rates in B-cell lymphomas but a lot of ibrutinib-treated patients relapse with resistance. This study unified TME-mediated de novo and acquired drug resistance through B-cell receptor signalling and PI3K-AKT-mTOR axis and provides a combination therapeutic strategy against B-cell malignancies. | | 18 April 2017 | doi: 10.1038/ncomms14920 | | | Optical-helicity-driven magnetization dynamics in metallic ferromagnets OPEN | | Gyung-Min Choi, André Schleife and David G. Cahill | | Optical switching of ferromagnets has attracted interest for use in ultrafast spintronics but the physical origin of the effect remains unclear. Here the authors determine the contributions of two proposed mechanisms, the inverse Faraday effect and optical spin-transfer torque. | | 18 April 2017 | doi: 10.1038/ncomms15085 | | | Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface OPEN | | HaoRan Tang, Leo Leung, Grazia Saturno, Amaya Viros, Duncan Smith, Gianpiero Di Leva, Eamonn Morrison, Dan Niculescu-Duvaz, Filipa Lopes, Louise Johnson, Nathalie Dhomen, Caroline Springer and Richard Marais | | Lysyl oxidase is able to remodel the extracellular matrix and its expression correlates with poor prognosis. Here the authors show that this protein modulates trapping of the epidermal growth factor receptor at the cell surface, causing persistent signalling activation and tumour progression. | | 18 April 2017 | doi: 10.1038/ncomms14909 | | | Neutrophil stunning by metoprolol reduces infarct size OPEN | | Jaime García-Prieto, Rocío Villena-Gutiérrez, Mónica Gómez, Esther Bernardo, Andrés Pun-García, Inés García-Lunar, Georgiana Crainiciuc, Rodrigo Fernández-Jiménez, Vinatha Sreeramkumar, Rafael Bourio-Martínez, José M García-Ruiz, Alfonso Serrano del Valle, David Sanz-Rosa, Gonzalo Pizarro, Antonio Fernández-Ortiz, Andrés Hidalgo, Valentín Fuster and Borja Ibanez | | Metoprolol is a selective β1 adrenergic receptor blocker that reduces cardiac infarct size and improves cardiac function. The drug is believed to act on cardiomyocytes; however, here the authors show that metoprolol exerts its beneficial effect on infarcted heart by targeting neutrophils and altering their function and interaction with platelets. | | 18 April 2017 | doi: 10.1038/ncomms14780 | | | Seismic anisotropy of the D″ layer induced by (001) deformation of post-perovskite OPEN | | Xiang Wu, Jung-Fu Lin, Pamela Kaercher, Zhu Mao, Jin Liu, Hans-Rudolf Wenk and Vitali B. Prakapenka | | The source of the anisotropic layer (D'' layer) at the bottom of the lower mantle remains unclear. Here, using high pressure and temperature experiments, the authors find that seismic anisotropy observed at the D'' layer is caused by 50% deformation of the minerals post-perovskite and ferropericlase. | | 18 April 2017 | doi: 10.1038/ncomms14669 | | | Chiral acidic amino acids induce chiral hierarchical structure in calcium carbonate OPEN | | Wenge Jiang, Michael S. Pacella, Dimitra Athanasiadou, Valentin Nelea, Hojatollah Vali, Robert M. Hazen, Jeffrey J. Gray and Marc D. McKee | | Chiral structures are formed in numerous processes including biomineralization of calcium carbonate. Here, the authors demonstrate that the chiral, hierarchically-organized architecture of the calcium carbonate mineral, vaterite, can be controlled simply by the addition of chiral acidic amino acids. | | 13 April 2017 | doi: 10.1038/ncomms15066 | | | Single-molecule electrical contacts on silicon electrodes under ambient conditions OPEN | | Albert C. Aragonès, Nadim Darwish, Simone Ciampi, Fausto Sanz, J. Justin Gooding and Ismael Díez-Pérez | | The next level of miniaturization of electronic circuits calls for a connection between current single-molecule and traditional semiconductor processing technologies. Here, the authors show a method to prepare metal/molecule/silicon diodes that present high current rectification ratios exceeding 4,000. | | 13 April 2017 | doi: 10.1038/ncomms15056 | | | Implantable batteryless device for on-demand and pulsatile insulin administration OPEN | | Seung Ho Lee, Young Bin Lee, Byung Hwi Kim, Cheol Lee, Young Min Cho, Se-Na Kim, Chun Gwon Park, Yong-Chan Cho and Young Bin Choy | | Implantable insulin delivery devices can make a significant difference in the lives of patients although they are limited by the duration of their battery life, often requiring replacement. Here, the authors developed an implantable battery-less insulin delivery device with noninvasive actuation. | | 13 April 2017 | doi: 10.1038/ncomms15032 | | | Nanoscale interface confinement of ultrafast spin transfer torque driving non-uniform spin dynamics OPEN | | Ilya Razdolski, Alexandr Alekhin, Nikita Ilin, Jan P. Meyburg, Vladimir Roddatis, Detlef Diesing, Uwe Bovensiepen and Alexey Melnikov | | Fundamental understanding of ultrafast spin dynamics is crucial for spintronics applications. Here the authors demonstrate an ultrafast technique to explore the inhomogeneous THz spin dynamics in Fe/Au/Fe multilayers triggered by spin transfer torque. | | 13 April 2017 | doi: 10.1038/ncomms15007 | | | Simultaneous loss of interlayer coherence and long-range magnetism in quasi-two-dimensional PdCrO2 OPEN | | S. Ghannadzadeh, S. Licciardello, S. Arsenijević, P. Robinson, H. Takatsu, M. I. Katsnelson and N. E. Hussey | | Incoherent transport is an important feature of many anisotropic quantum materials but often its origin is not well understood. Here, the authors show that in a layered quantum magnet, incoherence is driven by the interaction of electrons with spin fluctuations after the melting of magnetic order. | | 13 April 2017 | doi: 10.1038/ncomms15001 | | | Regio- and conformational isomerization critical to design of efficient thermally-activated delayed fluorescence emitters OPEN | | Marc K. Etherington, Flavio Franchello, Jamie Gibson, Thomas Northey, Jose Santos, Jonathan S. Ward, Heather F. Higginbotham, Przemyslaw Data, Aleksandra Kurowska, Paloma Lays Dos Santos, David R. Graves, Andrei S. Batsanov, Fernando B. Dias, Martin R. Bryce, Thomas J. Penfold and Andrew P. Monkman | | The search for brighter emitting materials is essential to the development of OLED devices. Etherington et al. show how the presence of two regioisomers of a donor-acceptor-donor thermally-activated delayed fluorescence molecule affects the device efficiency, with one acting as a triplet quencher. | | 13 April 2017 | doi: 10.1038/ncomms14987 | | | Tunable transmission of quantum Hall edge channels with full degeneracy lifting in split-gated graphene devices OPEN | | Katrin Zimmermann, Anna Jordan, Frédéric Gay, Kenji Watanabe, Takashi Taniguchi, Zheng Han, Vincent Bouchiat, Hermann Sellier and Benjamin Sacépé | | Quantum point contacts are gate-tunable constrictions allowing for control of charge carrier transmission in 2D electron gases. Here, the authors fabricate a hBN/graphene/hBN van der Waals heterojunction to enable quantum point contact devices in the integer and fractional quantum Hall regimes. | | 13 April 2017 | doi: 10.1038/ncomms14983 | | | Organic light emitting board for dynamic interactive display OPEN | | Eui Hyuk Kim, Sung Hwan Cho, Ju Han Lee, Beomjin Jeong, Richard Hahnkee Kim, Seunggun Yu, Tae-Woo Lee, Wooyoung Shim and Cheolmin Park | | Kim et al. report a polymeric-based electroluminescent interactive display that actively detects and visualizes an external conductive object under an alternating current. Fingerprint visualization and dynamic monitoring of metallic liquid flow are demonstrated. | | 13 April 2017 | doi: 10.1038/ncomms14964 | | | Rapid population decline in migratory shorebirds relying on Yellow Sea tidal mudflats as stopover sites OPEN | | Colin E. Studds, Bruce E. Kendall, Nicholas J. Murray, Howard B. Wilson, Danny I. Rogers, Robert S. Clemens, Ken Gosbell, Chris J. Hassell, Rosalind Jessop, David S. Melville, David A. Milton, Clive D. T. Minton, Hugh P. Possingham, Adrian C. Riegen, Phil Straw, Eric J. Woehler and Richard A. Fuller | | Stopover sites are crucial to migratory birds, but the influence of this habitat on population dynamics has not been quantified. Here, Studds et al. show that, among ten migratory species, the degree of reliance on disappearing stopover habitat in the Yellow Sea tidal flats predicts the extent of recent population declines. | | 13 April 2017 | doi: 10.1038/ncomms14895 | | | Pathways for balancing CO2 emissions and sinks OPEN | | Brian Walsh, Philippe Ciais, Ivan A. Janssens, Josep Peñuelas, Keywan Riahi, Felicjan Rydzak, Detlef P. van Vuuren and Michael Obersteiner | | COP21 led to a global commitment to decarbonization before 2100 to combat climate change, but leaves the timing and scale of mitigation efforts to individual countries. Here, the authors show that global carbon emissions need to peak within a decade to maintain realistic pathways for achieving the Paris Agreement. | | 13 April 2017 | doi: 10.1038/ncomms14856 | | | Intercalant-independent transition temperature in superconducting black phosphorus OPEN | | R. Zhang, J. Waters, A. K. Geim and I. V. Grigorieva | | No superconductivity could so far be achieved in black phosphorus in its normal orthorhombic form. Here, the authors demonstrate that intercalation with alkali metals makes black phosphorus superconducting with intercalant-independent transition temperature and near-identical superconducting characteristics. | | 12 April 2017 | doi: 10.1038/ncomms15036 | | | Inverting polar domains via electrical pulsing in metallic germanium telluride OPEN | | Pavan Nukala, Mingliang Ren, Rahul Agarwal, Jacob Berger, Gerui Liu, A. T. Charlie Johnson and Ritesh Agarwal | | Polar metals such as GeTe could store information using electric domains but the high conductivity screens electric fields, preventing the use of usual domain control techniques. Here, the authors demonstrate that polar domains in GeTe can be manipulated using electrically generated heat shocks. | | 12 April 2017 | doi: 10.1038/ncomms15033 | | | Probing the symmetry of the potential of localized surface plasmon resonances with phase-shaped electron beams OPEN | | Giulio Guzzinati, Armand Béché, Hugo Lourenço-Martins, Jérôme Martin, Mathieu Kociak and Jo Verbeeck | | The sign of the field in plasmonic excitations cannot be accessed by direct measurements. Here Guzzinati et al. overcome this limitation by shaping the wavefunction of an electron beam to match the symmetry of the plasmon’s charge symmetry, offering selective detection of specific plasmon modes. | | 12 April 2017 | doi: 10.1038/ncomms14999 | | | Nanomechanics of individual aerographite tetrapods OPEN | | Raimonds Meija, Stefano Signetti, Arnim Schuchardt, Kerstin Meurisch, Daria Smazna, Matthias Mecklenburg, Karl Schulte, Donats Erts, Oleg Lupan, Bodo Fiedler, Yogendra Kumar Mishra, Rainer Adelung and Nicola M. Pugno | | Aerographite is a highly porous and lightweight carbon material obtained from hollow tubular tetrapod building units. Here, the authors present a comprehensive investigation of tetrapod deformation mechanisms which are at the core of aerographite nanomechanical properties. | | 12 April 2017 | doi: 10.1038/ncomms14982 | | | Magnetically-driven colossal supercurrent enhancement in InAs nanowire Josephson junctions OPEN | | J. Tiira, E. Strambini, M. Amado, S. Roddaro, P. San-Jose, R. Aguado, F. S. Bergeret, D. Ercolani, L. Sorba and F. Giazotto | | Physical details of a Josephson junction may drastically modify the properties of supercurrent. Here, the authors observe a colossal enhancement of the critical supercurrent in a Josephson junction subject to a perpendicular magnetic field, indicating topological phase transitions. | | 12 April 2017 | doi: 10.1038/ncomms14984 | | | Genome assembly with in vitro proximity ligation data and whole-genome triplication in lettuce OPEN | | Sebastian Reyes-Chin-Wo, Zhiwen Wang, Xinhua Yang, Alexander Kozik, Siwaret Arikit, Chi Song, Liangfeng Xia, Lutz Froenicke, Dean O. Lavelle, María-José Truco, Rui Xia, Shilin Zhu, Chunyan Xu, Huaqin Xu, Xun Xu, Kyle Cox, Ian Korf, Blake C. Meyers and Richard W. Michelmore | | Genome assembly for many plant species can be challenging due to large size and high repeat content. Here, the authors use in vitro proximity ligation to assemble the genome of lettuce, revealing a family-specific triplication event and providing a comprehensive reference genome for a member of the Compositae. | | 12 April 2017 | doi: 10.1038/ncomms14953 | | | Stimuli-controlled self-assembly of diverse tubular aggregates from one single small monomer OPEN | | Qixun Shi, Tomas Javorskis, Karl-Erik Bergquist, Artūras Ulčinas, Gediminas Niaura, Ieva Matulaitienė, Edvinas Orentas and Kenneth Wärnmark | | Hydrogen bonds are powerful supramolecular motifs, owing to their selective and dynamic nature. Here, the authors build orthogonal hydrogen-bonding sites into a single molecule, allowing it to form diverse hierarchical assemblies and exhibit self-sorting behaviour in response to certain stimuli. | | 12 April 2017 | doi: 10.1038/ncomms14943 | | | Anisotropic forces from spatially constrained focal adhesions mediate contact guidance directed cell migration OPEN | | Arja Ray, Oscar Lee, Zaw Win, Rachel M. Edwards, Patrick W. Alford, Deok-Ho Kim and Paolo P. Provenzano | | Contact guidance on aligned substrates leads to directed cell migration through a poorly defined mechanism. Here the authors show that alignment of adhesion structures and F-actin generates anisotropic traction stress to drive directional migration, and cell-cell contact reduces force orientation and directional response. | | 12 April 2017 | doi: 10.1038/ncomms14923 | | | Electrically driven cation exchange for in situ fabrication of individual nanostructures OPEN | | Qiubo Zhang, Kuibo Yin, Hui Dong, Yilong Zhou, Xiaodong Tan, Kaihao Yu, Xiaohui Hu, Tao Xu, Chao Zhu, Weiwei Xia, Feng Xu, Haimei Zheng and Litao Sun | | Cation exchange, traditionally driven by ion solvation or thermal activation, is a robust approach for preparing heterogeneous nanostructures but lacks selectivity for preparation of individual nanocrystals. Here, the authors report an electrically driven cation exchange reaction that enables them to fabricate individual nanocrystals with high selectivity. | | 12 April 2017 | doi: 10.1038/ncomms14889 | | | Classical synchronization indicates persistent entanglement in isolated quantum systems OPEN | | Dirk Witthaut, Sandro Wimberger, Raffaella Burioni and Marc Timme | | Collective phenomena in many-body systems include synchronization in classical and entanglement in quantum systems. Here the authors study isolated many-body quantum systems and demonstrate that synchronization emerges intrinsically, accompanied by the onset of quantum coherence and persistent entanglement. | | 12 April 2017 | doi: 10.1038/ncomms14829 | | | Cognate antigen engagement on parenchymal cells stimulates CD8+ T cell proliferation in situ OPEN | | Robyn M. Sutherland, Sarah L. Londrigan, Jamie L. Brady, Emma M. Carrington, Julia M. Marchingo, Susanne Heinzel, Philip D. Hodgkin, Kate L. Graham, Thomas W. Kay, Yifan Zhan and Andrew M. Lew | | Professional antigen presenting cells (APC) are the major activator of T cells that then hone to sites of inflammation. Using islet cell grafts, here the authors show that parenchymal cells can present antigen to activate CD8+ T cells at inflammatory sites, coining this a ‘mezzanine response’ distinct from primary and secondary responses associated with professional APCs. | | 12 April 2017 | doi: 10.1038/ncomms14809 | | | Multiscale structural and electronic control of molybdenum disulfide foam for highly efficient hydrogen production OPEN | | Jiao Deng, Haobo Li, Suheng Wang, Ding Ding, Mingshu Chen, Chuan Liu, Zhongqun Tian, K. S. Novoselov, Chao Ma, Dehui Deng and Xinhe Bao | | The hydrogen evolution reaction is a complicated process involving liquid-solid-gas three-phase interface behaviour. Here, the authors report the multiscale structural and electronic control of molybdenum disulfide foam and demonstrate its high activity and stability for hydrogen evolution. | | 12 April 2017 | doi: 10.1038/ncomms14430 | | | | | | | | | | | Latest Corrigenda | | | | Corrigendum: The OncoPPi network of cancer-focused protein–protein interactions to inform biological insights and therapeutic strategies OPEN | | Zenggang Li, Andrei A. Ivanov, Rina Su, Valentina Gonzalez-Pecchi, Qi Qi, Songlin Liu, Philip Webber, Elizabeth McMillan, Lauren Rusnak, Cau Pham, Xiaoqian Chen, Xiulei Mo, Brian Revennaugh, Wei Zhou, Adam Marcus, Sahar Harati, Xiang Chen, Margaret A. Johns, Michael A. White, Carlos S. Moreno et al. | | 18 April 2017 | doi: 10.1038/ncomms15350 | | |
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