Monday, March 13, 2017

Nature Reviews Microbiology contents April 2017 Volume 15 Number 4 pp 193-254

Nature Reviews Microbiology

Advertisement webcasts

Springer Nature presents a custom webcast on: Analyzing Ebola virus glycoprotein and its interactions with therapeutic antibodies using CG-MALS

Date: Wednesday, March 15, 2017
Time: 8am PDT | 11am EDT | 3pm GMT | 4pm CET

Register for FREE

Sponsored by: Wyatt Technology Corporation
April 2017 Volume 15 Number 4
Nature Reviews Microbiology cover
2015 2-year Impact Factor 24.727 Journal Metrics 2-year Median 19.5
In this issue
Research Highlights
News and Analysis

Also this month
Article series:
Vector-borne diseases
 Featured article:
Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need
Mark C. Field, David Horn, Alan H. Fairlamb, Michael A. J. Ferguson, David W. Gray, Kevin D. Read, Manu De Rycker, Leah S. Torrie, Paul G. Wyatt, Susan Wyllie & Ian H. Gilbert

Recommend to library
Nature Reviews Microbiology: Collection on Antimicrobial Resistance 

This collection of articles from several Nature journals describes how antimicrobial resistance emerges and details discovery strategies for urgently needed new antimicrobials. 

Access this collection free online for six months

Produced with support from 
Merck & Co., Inc., Kenilworth, NJ, USA

Bacterial physiology: Treadmilling runs bacterial division
p193 | doi:10.1038/nrmicro.2017.24
Two new studies show that FtsZ treadmilling controls and organizes cell wall synthesis to drive bacterial cell division.


Bacterial physiology: Persisters running out of energy
p194 | doi:10.1038/nrmicro.2017.19
This study shows that ATP depletion lowers the antibiotic target activity and thus functions as a general mechanism for the formation of persisters.


CRISPR patent results

p194 | doi:10.1038/nrmicro.2017.21
The CRISPR-Cas9 patents filed by the Broad Institute are upheld by the US Patent and Trademark Office


Symbiosis: Wolbachia's matchmaking secret revealed
p194 | doi:10.1038/nrmicro.2017.25
Two new studies identify the basis of cytoplasmic incompatibility, a process by which obligate intracellular Wolbachia bacteria favour their inheritance in their female insect hosts.


Bacterial pathogenesis: Hitching a ride with DCs
p195 | doi:10.1038/nrmicro.2017.18
Pseudogenization of a single Salmonella effector protein gene facilitates pathogen hijacking of dendritic cells for systemic spread.


Bringing Treponema into the spotlight
Isobel Everall & Leonor Sanchez-Buso
p196 | doi:10.1038/nrmicro.2017.23
This month's Genome Watch highlights how culture-independent selective enrichment approaches coupled to whole-genome sequencing enable the analysis of unculturable microorganisms.

The β-barrel assembly machinery in motion
Nicholas Noinaj, James C. Gumbart & Susan K. Buchanan
p197 | doi:10.1038/nrmicro.2016.191
In this Progress article, Buchanan and colleagues discuss recent studies that have advanced our understanding of the structure of the fully assembled β-barrel assembly machinery (BAM) complex and the interactions between the individual components. They also detail the mechanistic insights that have been gained and explore two emerging models for BAM-mediated outer membrane protein biogenesis in bacteria.

Abstract | Full Text | PDF
Open for Submissions

A new open access, multi-and interdisciplinary journal dedicated to publishing the finest research on both microbial biofilms and microbiomes, the journal is now open for submissions.

Explore the benefits of submitting your next research article.
Virus–host interactions and their roles in coral reef health and disease
Rebecca Vega Thurber, Jérôme P. Payet, Andrew R. Thurber & Adrienne M. S. Correa
p205 | doi:10.1038/nrmicro.2016.176
Coral reefs are complex ecosystems that are populated by diverse microorganisms. In this Review, Vega Thurber et al. summarize the diversity of reef viruses that infect corals and their associated microbiota, and highlight their roles in coral disease and reef decline.
Abstract | Full Text | PDF

Article series: Vector-borne diseases
Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need
Mark C. Field, David Horn, Alan H. Fairlamb, Michael A. J. Ferguson, David W. Gray, Kevin D. Read, Manu De Rycker, Leah S. Torrie, Paul G. Wyatt, Susan Wyllie & Ian H. Gilbert
p217 | doi:10.1038/nrmicro.2016.193
Trypanosomatid parasites can cause life-threatening diseases, such as human African trypanosomiasis, leishmaniasis and Chagas disease. In this Review, Gilbert and colleagues discuss the drug discovery landscape and describe some of the challenges that are involved in the development of new drugs to treat these diseases.
Abstract | Full Text | PDF

Timing the day: what makes bacterial clocks tick?
Carl Hirschie Johnson, Chi Zhao, Yao Xu & Tetsuya Mori
p232 | doi:10.1038/nrmicro.2016.196
Circadian rhythms enable cells to anticipate cyclic changes in their environment. In this Review, Johnson et al. explore timekeeping systems that range from prototypical circadian clocks to hourglass timers and their role in different bacteria, including cyanobacteria and members of the microbiota.
Abstract | Full Text | PDF

Mimivirus: leading the way in the discovery of giant viruses of amoebae
Philippe Colson, Bernard La Scola, Anthony Levasseur, Gustavo Caetano-Anollés & Didier Raoult
p243 | doi:10.1038/nrmicro.2016.197
The discovery of the giant amoebal virus mimivirus, in 2003, opened up a new area of virology. Extended studies, including those of mimiviruses, have since revealed that these viruses have genetic, proteomic and structural features that are more complex than those of conventional viruses.
Abstract | Full Text | PDF | Supplementary information

An open access, online-only, multidisciplinary research journal dedicated to publishing the most important scientific advances in the life sciences, physical sciences, and engineering fields that are facilitated by spaceflight and analogue platforms.
Explore the benefits of submitting your next research article.
nature events
Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here.

Find the latest scientific conferences, courses, meetings and symposia on For event advertising opportunities across the Nature Publishing Group portfolio please contact
More Nature Events

You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your account at:
(You will need to log in to be recognised as a registrant).

For further technical assistance, please contact our registration department

For print subscription enquiries, please contact our subscription department

For other enquiries, please contact our feedback department

Nature Publishing Group | One New York Plaza, Suite 4500 | New York | NY 10004-1562 | USA

Nature Publishing Group's worldwide offices:
London - Paris - Munich - New Delhi - Tokyo - Melbourne
San Diego - San Francisco - Washington - New York - Boston

Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at The Campus, 4 Crinan Street, London, N1 9XW.

© 2017 Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.

nature publishing group

No comments: