Wednesday, December 28, 2016

Cell Death and Disease - Table of Contents alert Volume 7, December 2016

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Cell Death and Disease

Online-only and open access, Cell Death Discovery publishes scientifically sound research at the intersection of cell death and medicine. Increasing the reproducibility of research, the journal fosters a dynamic dialogue with a focus on cancer, neurobiology and inflammation research.

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Volume 7, December 2016

In this issue
News and Commentary
Original Articles
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Cell Death & Disease is an online-only, open access journal seeking to promote diverse and integrated areas of experimental and internal medicine with its specialities, including cancer, cancer metabolism, immunity and neuroscience.

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BNC2 is a putative tumor suppressor gene in high-grade serous ovarian carcinoma and impacts cell survival after oxidative stress

Laura Cesaratto, Eleonora Grisard, Michela Coan, Luigi Zandonà, Elena De Mattia, Elena Poletto, Erika Cecchin, Fabio Puglisi, Vincenzo Canzonieri, Maria Teresa Mucignat, Antonella Zucchetto, Gabriele Stocco, Alfonso Colombatti, Milena S Nicoloso and Riccardo Spizzo

Cell Death Dis 2016 7: e2526; 10.1038/cddis.2016.448

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MicroRNA-587 antagonizes 5-FU-induced apoptosis and confers drug resistance by regulating PPP2R1B expression in colorectal cancer

Y Zhang, G Talmon and J Wang

Cell Death Dis 2016 7: e2525; 10.1038/cddis.2016.450

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News and Commentary


Discovery of a novel target for cancer: PRR14

Shaowen Xiao and Mei Yang

Cell Death Dis 2016 7: e2502; 10.1038/cddis.2016.401

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Inflammation and Notch signaling: a crosstalk with opposite effects on tumorigenesis

Chiara Fazio and Luigi Ricciardiello

Cell Death Dis 2016 7: e2515; 10.1038/cddis.2016.408

Abstract | Full Text

Autophagy and epithelial–mesenchymal transition: an intricate interplay in cancer

Mila Gugnoni, Valentina Sancisi, Gloria Manzotti, Greta Gandolfi and Alessia Ciarrocchi

Cell Death Dis 2016 7: e2520; 10.1038/cddis.2016.415

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Extracellular histones, cell-free DNA, or nucleosomes: differences in immunostimulation

Gerben Marsman, Sacha Zeerleder and Brenda M Luken

Cell Death Dis 2016 7: e2518; 10.1038/cddis.2016.410

Abstract | Full Text

Original Articles


‘Normalizing’ the malignant phenotype of luminal breast cancer cells via alpha(v)beta(3)-integrin

Hanan Abu-Tayeh, Keren Weidenfeld, Alisa Zhilin-Roth, Sagi Schif-Zuck, Sonja Thaler, Cristina Cotarelo, Tuan Z Tan, Jean P Thiery, Jeffrey E Green, Geula Klorin, Edmond Sabo, Jonathan P Sleeman, Maty Tzukerman and Dalit Barkan

Cell Death Dis 2016 7: e2491; 10.1038/cddis.2016.387

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TRAP1 downregulation in human ovarian cancer enhances invasion and epithelial–mesenchymal transition

Maria R Amoroso, Danilo S Matassa, Ilenia Agliarulo, Rosario Avolio, Haonan Lu, Lorenza Sisinni, Giacomo Lettini, Hani Gabra, Matteo Landriscina and Franca Esposito

Cell Death Dis 2016 7: e2522; 10.1038/cddis.2016.400

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Anti-proliferative activity of the NPM1 interacting natural product avrainvillamide in acute myeloid leukemia

Vibeke Andresen, Bjarte S Erikstein, Herschel Mukherjee, André Sulen, Mihaela Popa, Steinar Sørnes, Håkon Reikvam, Kok-Ping Chan, Randi Hovland, Emmet McCormack, Øystein Bruserud, Andrew G Myers and Bjørn T Gjertsen

Cell Death Dis 2016 7: e2497; 10.1038/cddis.2016.392

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Sensitivity of hematopoietic stem cells to mitochondrial dysfunction by SdhD gene deletion

José Antonio Bejarano-García, África Millán-Uclés, Iván V Rosado, Luís Ignacio Sánchez-Abarca, Teresa Caballero-Velázquez, María José Durán-Galván, José Antonio Pérez-Simón and José I Piruat

Cell Death Dis 2016 7: e2516; 10.1038/cddis.2016.411

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Bcl-3 regulates TGFβ signaling by stabilizing Smad3 during breast cancer pulmonary metastasis

Xi Chen, Xinwei Cao, Xiaohua Sun, Rong Lei, Pengfei Chen, Yongxu Zhao, Yuhang Jiang, Jie Yin, Ran Chen, Deji Ye, Qi Wang, Zhanjie Liu, Sanhong Liu, Chunyan Cheng, Jie Mao, Yingyong Hou, Mingliang Wang, Ulrich Siebenlist, Y Eugene Chin, Ying Wang, Liu Cao, Guohong Hu and Xiaoren Zhang

Cell Death Dis 2016 7: e2508; 10.1038/cddis.2016.405

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Downregulation of ASPP2 improves hepatocellular carcinoma cells survival via promoting BECN1-dependent autophagy initiation

Rui Chen, Hao Wang, Beibei Liang, Guoke Liu, Min Tang, Rongjie Jia, Xiaoyu Fan, Wei Jing, Xuyu Zhou, Huajing Wang, Yang Yang, Huafeng Wei, Bohua Li and Jian Zhao

Cell Death Dis 2016 7: e2512; 10.1038/cddis.2016.407

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Systemic application of 3-methyladenine markedly inhibited atherosclerotic lesion in ApoE/ mice by modulating autophagy, foam cell formation and immune-negative molecules

Shen Dai, Bo Wang, Wen Li, Liyang Wang, Xingguo Song, Chun Guo, Yulan Li, Fengming Liu, Faliang Zhu, Qun Wang, Xiaoyan Wang, Yongyu Shi, Jianing Wang, Wei Zhao and Lining Zhang

Cell Death Dis 2016 7: e2498; 10.1038/cddis.2016.376

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Sensitivity of GBM cells to cAMP agonist-mediated apoptosis correlates with CD44 expression and agonist resistance with MAPK signaling

Paul M Daniel, Gulay Filiz and Theo Mantamadiotis

Cell Death Dis 2016 7: e2494; 10.1038/cddis.2016.393

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Impaired haematopoietic stem cell differentiation and enhanced skewing towards myeloid progenitors in aged caspase-2-deficient mice

Swati Dawar, Nur Hezrin Shahrin, Nikolina Sladojevic, Richard J D'Andrea, Loretta Dorstyn, Devendra K Hiwase and Sharad Kumar

Cell Death Dis 2016 7: e2509; 10.1038/cddis.2016.406

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Robust high-throughput kinetic analysis of apoptosis with real-time high-content live-cell imaging

Jesse D Gelles and Jerry Edward Chipuk

Cell Death Dis 2016 7: e2493; 10.1038/cddis.2016.332

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Epigenetic programming of Dnmt3a mediated by AP2α is required for granting preadipocyte the ability to differentiate

Wei Guo, Jiangnan Chen, Ying Yang, Jianbei Zhu and Jiarui Wu

Cell Death Dis 2016 7: e2496; 10.1038/cddis.2016.378

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Combined nifuroxazide and SAT05f therapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantation

Huijie Jia, Tiesuo Zhao, Yinghua Ji, Xiaolong Jia, Wenjing Ren, Chen Li, Minming Li, Yali Xiao, Hui Wang and Kailin Xu

Cell Death Dis 2016 7: e2507; 10.1038/cddis.2016.399

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STAT6 deficiency ameliorates Graves’ disease severity by suppressing thyroid epithelial cell hyperplasia

Xuechao Jiang, Bingbing Zha, Xiaoming Liu, Ronghua Liu, Jun Liu, Enyu Huang, Tingting Qian, Jiajing Liu, Zhiming Wang, Dan Zhang, Luman Wang and Yiwei Chu

Cell Death Dis 2016 7: e2506; 10.1038/cddis.2016.398

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Dual targeting of glutaminase 1 and thymidylate synthase elicits death synergistically in NSCLC

Jae-Seon Lee, Joon H Kang, Seon-Hyeong Lee, Dongwan Hong, Jaekyoung Son, Kyeong M Hong, Jaewhan Song and Soo-Youl Kim

Cell Death Dis 2016 7: e2511; 10.1038/cddis.2016.404

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Hypericin-mediated sonodynamic therapy induces autophagy and decreases lipids in THP-1 macrophage by promoting ROS-dependent nuclear translocation of TFEB

Xuesong Li, Xin Zhang, Longbin Zheng, Jiayuan Kou, Zhaoyu Zhong, Yueqing Jiang, Wei Wang, Zengxiang Dong, Zhongni Liu, Xiaobo Han, Jing Li, Ye Tian, Yajun Zhao and Liming Yang

Cell Death Dis 2016 7: e2527; 10.1038/cddis.2016.433

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Therapeutic advantage of pro-electrophilic drugs to activate the Nrf2/ARE pathway in Alzheimer’s disease models

Stuart A Lipton, Tayebeh Rezaie, Anthony Nutter, Kevin M Lopez, James Parker, Kunio Kosaka, Takumi Satoh, Scott R McKercher, Eliezer Masliah and Nobuki Nakanishi

Cell Death Dis 2016 7: e2499; 10.1038/cddis.2016.389

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Large-scale pharmacological profiling of 3D tumor models of cancer cells

Lesley A Mathews Griner, Xiaohu Zhang, Rajarshi Guha, Crystal McKnight, Ian S Goldlust, Madhu Lal-Nag, Kelli Wilson, Sam Michael, Steve Titus, Paul Shinn, Craig J Thomas and Marc Ferrer

Cell Death Dis 2016 7: e2492; 10.1038/cddis.2016.360

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Inflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosis

Xiao-Ming Meng, Shuang Wang, Xiao-Ru Huang, Chen Yang, Jun Xiao, Yang Zhang, Ka-Fai To, David J Nikolic-Paterson and Hui-Yao Lan

Cell Death Dis 2016 7: e2495; 10.1038/cddis.2016.402

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Preimplantation factor is an anti-apoptotic effector in human trophoblasts involving p53 signaling pathway

Hadia Moindjie, Esther Dos Santos, Rita-Josiane Gouesse, Nelly Swierkowski-Blanchard, Valérie Serazin, Eytan R Barnea, François Vialard and Marie-Noëlle Dieudonné

Cell Death Dis 2016 7: e2504; 10.1038/cddis.2016.382

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Non-amyloidogenic effects of α2 adrenergic agonists: implications for brimonidine-mediated neuroprotection

Shereen Nizari, Li Guo, Benjamin M Davis, Eduardo M Normando, Joana Galvao, Lisa A Turner, Mukhtar Bizrah, Mohammad Dehabadi, Kailin Tian and M Francesca Cordeiro

Cell Death Dis 2016 7: e2514; 10.1038/cddis.2016.397

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Phosphorylated STAT5 regulates p53 expression via BRCA1/BARD1-NPM1 and MDM2

Zhuo Ren, Joeri L Aerts, Hugo Vandenplas, Jiance A Wang, Olena Gorbenko, Jack P Chen, Philippe Giron, Carlo Heirman, Cleo Goyvaerts, Eldad Zacksenhaus, Mark D Minden, Vuk Stambolic, Karine Breckpot and Jacques De Grève

Cell Death Dis 2016 7: e2560; 10.1038/cddis.2016.430

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Distinct outcomes of CRL–Nedd8 pathway inhibition reveal cancer cell plasticity

Anastasia V Rulina, Frédérique Mittler, Patricia Obeid, Sophie Gerbaud, Laurent Guyon, Eric Sulpice, Frédérique Kermarrec, Nicole Assard, Monika E Dolega, Xavier Gidrol and Maxim Y Balakirev

Cell Death Dis 2016 7: e2505; 10.1038/cddis.2016.395

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A mechanism for overcoming P-glycoprotein-mediated drug resistance: novel combination therapy that releases stored doxorubicin from lysosomes via lysosomal permeabilization using Dp44mT or DpC

Nicole A Seebacher, Des R Richardson and Patric J Jansson

Cell Death Dis 2016 7: e2510; 10.1038/cddis.2016.381

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Human umbilical cord blood-stem cells direct macrophage polarization and block inflammasome activation to alleviate rheumatoid arthritis

Tae-Hoon Shin, Hyung-Sik Kim, Tae-Wook Kang, Byung-Chul Lee, Hwa-Yong Lee, Yoon-Jin Kim, Ji-Hee Shin, Yoojin Seo, Soon Won Choi, Seunghee Lee, Kichul Shin, Kwang-Won Seo and Kyung-Sun Kang

Cell Death Dis 2016 7: e2524; 10.1038/cddis.2016.442

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Hyperhomocysteinemia causes ER stress and impaired autophagy that is reversed by Vitamin B supplementation

Madhulika Tripathi, Cheng Wu Zhang, Brijesh Kumar Singh, Rohit Anthony Sinha, Kyaw Thu Moe, Deidre Anne DeSilva and Paul Michael Yen

Cell Death Dis 2016 7: e2513; 10.1038/cddis.2016.374

Abstract | Full Text

miR-148a-3p represses proliferation and EMT by establishing regulatory circuits between ERBB3/AKT2/c-myc and DNMT1 in bladder cancer

Xiao Wang, Zhen Liang, Xin Xu, Jiangfeng Li, Yi Zhu, Shuai Meng, Shiqi Li, Song Wang, Bo Xie, Alin Ji, Ben Liu, Xiangyi Zheng and Liping Xie

Cell Death Dis 2016 7: e2503; 10.1038/cddis.2016.373

Abstract | Full Text

Upregulation of MiR-205 under hypoxia promotes epithelial–mesenchymal transition by targeting ASPP2

Xingwen Wang, Miao Yu, Kunming Zhao, Mengmeng He, Wenjie Ge, Yuhui Sun, Yihua Wang, Haizhu Sun and Ying Hu

Cell Death Dis 2016 7: e2517; 10.1038/cddis.2016.412

Abstract | Full Text

1-Methyl-tryptophan attenuates regulatory T cells differentiation due to the inhibition of estrogen-IDO1-MRC2 axis in endometriosis

Chunyan Wei, Jie Mei, Lingli Tang, Yukai Liu, Dajin Li, Mingqing Li and Xiaoyong Zhu

Cell Death Dis 2016 7: e2489; 10.1038/cddis.2016.375

Abstract | Full Text

The Yersinia Type III secretion effector YopM Is an E3 ubiquitin ligase that induced necrotic cell death by targeting NLRP3

Congwen Wei, Ying Wang, Zongmin Du, Kai Guan, Ye Cao, Huiying Yang, Pengyu Zhou, Feixiang Wu, Jiankang Chen, Penghao Wang, Zirui Zheng, Pingping Zhang, Yanhong Zhang, Shengli Ma, Ruifu Yang, Hui Zhong and Xiang He

Cell Death Dis 2016 7: e2519; 10.1038/cddis.2016.413

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Downregulated expression of microRNA-124 in pediatric intestinal failure patients modulates macrophages activation by inhibiting STAT3 and AChE

Yong-Tao Xiao, Jun Wang, Wei Lu, Yi Cao and Wei Cai

Cell Death Dis 2016 7: e2521; 10.1038/cddis.2016.426

Abstract | Full Text

Rab17 mediates differential antigen sorting following efferocytosis and phagocytosis

Charles Yin, Yohan Kim, Dean Argintaru and Bryan Heit

Cell Death Dis 2016 7: e2529; 10.1038/cddis.2016.431

Abstract | Full Text

Smad3-related miRNAs regulated oncogenic TRIB2 promoter activity to effectively suppress lung adenocarcinoma growth

Yan-Xia Zhang, Yun-Fei Yan, Yue-Mei Liu, You-Jie Li, Han-Han Zhang, Min Pang, Jin-Xia Hu, Wei Zhao, Ning Xie, Ling Zhou, Ping-Yu Wang and Shu-Yang Xie

Cell Death Dis 2016 7: e2528; 10.1038/cddis.2016.432

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Rab8a/Rab11a regulate intercellular communications between neural cells via tunneling nanotubes

Hui Zhu, Chengbin Xue, Xi Xu, Yibing Guo, Xiaohong Li, Jingjing Lu, Shaoqing Ju, Yongjun Wang, Zheng Cao and Xiaosong Gu

Cell Death Dis 2016 7: e2523; 10.1038/cddis.2016.441

Abstract | Full Text

PINK1-dependent phosphorylation of PINK1 and Parkin is essential for mitochondrial quality control

Na Zhuang, Lin Li, She Chen and Tao Wang

Cell Death Dis 2016 7: e2501; 10.1038/cddis.2016.396

Abstract | Full Text



Male sterility in Mcl-1-flox mice is not due to enhanced Mcl1 protein stability

Casey Ah-Cann, Maximilien Tailler, Andrew J Kueh, Marco J Herold, Joseph T Opferman, Marie-Liesse Asselin-Labat and Philippe Bouillet

Cell Death Dis 2016 7: e2490; 10.1038/cddis.2016.391

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