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TABLE OF CONTENTS
| | | | Volume 7, December 2016 | | In this issue Corrigendum Erratum News and Commentary Reviews Original Articles Correspondence | | | | | Advertisement | | Cell Death & Disease is an online-only, open access journal seeking to promote diverse and integrated areas of experimental and internal medicine with its specialities, including cancer, cancer metabolism, immunity and neuroscience.
Explore the benefits of submitting your next research article. | | | | | | Corrigendum | Top | | BNC2 is a putative tumor suppressor gene in high-grade serous ovarian carcinoma and impacts cell survival after oxidative stressLaura Cesaratto, Eleonora Grisard, Michela Coan, Luigi Zandonà, Elena De Mattia, Elena Poletto, Erika Cecchin, Fabio Puglisi, Vincenzo Canzonieri, Maria Teresa Mucignat, Antonella Zucchetto, Gabriele Stocco, Alfonso Colombatti, Milena S Nicoloso and Riccardo Spizzo Cell Death Dis 2016 7: e2526; 10.1038/cddis.2016.448 Full Text | | Erratum | Top | | MicroRNA-587 antagonizes 5-FU-induced apoptosis and confers drug resistance by regulating PPP2R1B expression in colorectal cancerY Zhang, G Talmon and J Wang Cell Death Dis 2016 7: e2525; 10.1038/cddis.2016.450 Full Text | | News and Commentary | Top | | Discovery of a novel target for cancer: PRR14Shaowen Xiao and Mei Yang Cell Death Dis 2016 7: e2502; 10.1038/cddis.2016.401 Full Text | | Reviews | Top | | Inflammation and Notch signaling: a crosstalk with opposite effects on tumorigenesisChiara Fazio and Luigi Ricciardiello Cell Death Dis 2016 7: e2515; 10.1038/cddis.2016.408 Abstract | Full Text | | | | Autophagy and epithelial–mesenchymal transition: an intricate interplay in cancerMila Gugnoni, Valentina Sancisi, Gloria Manzotti, Greta Gandolfi and Alessia Ciarrocchi Cell Death Dis 2016 7: e2520; 10.1038/cddis.2016.415 Abstract | Full Text | | | | Extracellular histones, cell-free DNA, or nucleosomes: differences in immunostimulationGerben Marsman, Sacha Zeerleder and Brenda M Luken Cell Death Dis 2016 7: e2518; 10.1038/cddis.2016.410 Abstract | Full Text | | Original Articles | Top | | ‘Normalizing’ the malignant phenotype of luminal breast cancer cells via alpha(v)beta(3)-integrinHanan Abu-Tayeh, Keren Weidenfeld, Alisa Zhilin-Roth, Sagi Schif-Zuck, Sonja Thaler, Cristina Cotarelo, Tuan Z Tan, Jean P Thiery, Jeffrey E Green, Geula Klorin, Edmond Sabo, Jonathan P Sleeman, Maty Tzukerman and Dalit Barkan Cell Death Dis 2016 7: e2491; 10.1038/cddis.2016.387 Abstract | Full Text | | | | TRAP1 downregulation in human ovarian cancer enhances invasion and epithelial–mesenchymal transitionMaria R Amoroso, Danilo S Matassa, Ilenia Agliarulo, Rosario Avolio, Haonan Lu, Lorenza Sisinni, Giacomo Lettini, Hani Gabra, Matteo Landriscina and Franca Esposito Cell Death Dis 2016 7: e2522; 10.1038/cddis.2016.400 Abstract | Full Text | | | | Anti-proliferative activity of the NPM1 interacting natural product avrainvillamide in acute myeloid leukemiaVibeke Andresen, Bjarte S Erikstein, Herschel Mukherjee, André Sulen, Mihaela Popa, Steinar Sørnes, Håkon Reikvam, Kok-Ping Chan, Randi Hovland, Emmet McCormack, Øystein Bruserud, Andrew G Myers and Bjørn T Gjertsen Cell Death Dis 2016 7: e2497; 10.1038/cddis.2016.392 Abstract | Full Text | | | | Sensitivity of hematopoietic stem cells to mitochondrial dysfunction by SdhD gene deletionJosé Antonio Bejarano-García, África Millán-Uclés, Iván V Rosado, Luís Ignacio Sánchez-Abarca, Teresa Caballero-Velázquez, María José Durán-Galván, José Antonio Pérez-Simón and José I Piruat Cell Death Dis 2016 7: e2516; 10.1038/cddis.2016.411 Abstract | Full Text | | | | Bcl-3 regulates TGFβ signaling by stabilizing Smad3 during breast cancer pulmonary metastasisXi Chen, Xinwei Cao, Xiaohua Sun, Rong Lei, Pengfei Chen, Yongxu Zhao, Yuhang Jiang, Jie Yin, Ran Chen, Deji Ye, Qi Wang, Zhanjie Liu, Sanhong Liu, Chunyan Cheng, Jie Mao, Yingyong Hou, Mingliang Wang, Ulrich Siebenlist, Y Eugene Chin, Ying Wang, Liu Cao, Guohong Hu and Xiaoren Zhang Cell Death Dis 2016 7: e2508; 10.1038/cddis.2016.405 Abstract | Full Text | | | | Downregulation of ASPP2 improves hepatocellular carcinoma cells survival via promoting BECN1-dependent autophagy initiationRui Chen, Hao Wang, Beibei Liang, Guoke Liu, Min Tang, Rongjie Jia, Xiaoyu Fan, Wei Jing, Xuyu Zhou, Huajing Wang, Yang Yang, Huafeng Wei, Bohua Li and Jian Zhao Cell Death Dis 2016 7: e2512; 10.1038/cddis.2016.407 Abstract | Full Text | | | | Systemic application of 3-methyladenine markedly inhibited atherosclerotic lesion in ApoE−/− mice by modulating autophagy, foam cell formation and immune-negative moleculesShen Dai, Bo Wang, Wen Li, Liyang Wang, Xingguo Song, Chun Guo, Yulan Li, Fengming Liu, Faliang Zhu, Qun Wang, Xiaoyan Wang, Yongyu Shi, Jianing Wang, Wei Zhao and Lining Zhang Cell Death Dis 2016 7: e2498; 10.1038/cddis.2016.376 Abstract | Full Text | | | | Sensitivity of GBM cells to cAMP agonist-mediated apoptosis correlates with CD44 expression and agonist resistance with MAPK signalingPaul M Daniel, Gulay Filiz and Theo Mantamadiotis Cell Death Dis 2016 7: e2494; 10.1038/cddis.2016.393 Abstract | Full Text | | | | Impaired haematopoietic stem cell differentiation and enhanced skewing towards myeloid progenitors in aged caspase-2-deficient miceSwati Dawar, Nur Hezrin Shahrin, Nikolina Sladojevic, Richard J D'Andrea, Loretta Dorstyn, Devendra K Hiwase and Sharad Kumar Cell Death Dis 2016 7: e2509; 10.1038/cddis.2016.406 Abstract | Full Text | | | | Robust high-throughput kinetic analysis of apoptosis with real-time high-content live-cell imagingJesse D Gelles and Jerry Edward Chipuk Cell Death Dis 2016 7: e2493; 10.1038/cddis.2016.332 Abstract | Full Text | | | | Epigenetic programming of Dnmt3a mediated by AP2α is required for granting preadipocyte the ability to differentiateWei Guo, Jiangnan Chen, Ying Yang, Jianbei Zhu and Jiarui Wu Cell Death Dis 2016 7: e2496; 10.1038/cddis.2016.378 Abstract | Full Text | | | | Combined nifuroxazide and SAT05f therapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantationHuijie Jia, Tiesuo Zhao, Yinghua Ji, Xiaolong Jia, Wenjing Ren, Chen Li, Minming Li, Yali Xiao, Hui Wang and Kailin Xu Cell Death Dis 2016 7: e2507; 10.1038/cddis.2016.399 Abstract | Full Text | | | | STAT6 deficiency ameliorates Graves’ disease severity by suppressing thyroid epithelial cell hyperplasiaXuechao Jiang, Bingbing Zha, Xiaoming Liu, Ronghua Liu, Jun Liu, Enyu Huang, Tingting Qian, Jiajing Liu, Zhiming Wang, Dan Zhang, Luman Wang and Yiwei Chu Cell Death Dis 2016 7: e2506; 10.1038/cddis.2016.398 Abstract | Full Text | | | | Dual targeting of glutaminase 1 and thymidylate synthase elicits death synergistically in NSCLCJae-Seon Lee, Joon H Kang, Seon-Hyeong Lee, Dongwan Hong, Jaekyoung Son, Kyeong M Hong, Jaewhan Song and Soo-Youl Kim Cell Death Dis 2016 7: e2511; 10.1038/cddis.2016.404 Abstract | Full Text | | | | Hypericin-mediated sonodynamic therapy induces autophagy and decreases lipids in THP-1 macrophage by promoting ROS-dependent nuclear translocation of TFEBXuesong Li, Xin Zhang, Longbin Zheng, Jiayuan Kou, Zhaoyu Zhong, Yueqing Jiang, Wei Wang, Zengxiang Dong, Zhongni Liu, Xiaobo Han, Jing Li, Ye Tian, Yajun Zhao and Liming Yang Cell Death Dis 2016 7: e2527; 10.1038/cddis.2016.433 Abstract | Full Text | | | | Therapeutic advantage of pro-electrophilic drugs to activate the Nrf2/ARE pathway in Alzheimer’s disease modelsStuart A Lipton, Tayebeh Rezaie, Anthony Nutter, Kevin M Lopez, James Parker, Kunio Kosaka, Takumi Satoh, Scott R McKercher, Eliezer Masliah and Nobuki Nakanishi Cell Death Dis 2016 7: e2499; 10.1038/cddis.2016.389 Abstract | Full Text | | | | Large-scale pharmacological profiling of 3D tumor models of cancer cellsLesley A Mathews Griner, Xiaohu Zhang, Rajarshi Guha, Crystal McKnight, Ian S Goldlust, Madhu Lal-Nag, Kelli Wilson, Sam Michael, Steve Titus, Paul Shinn, Craig J Thomas and Marc Ferrer Cell Death Dis 2016 7: e2492; 10.1038/cddis.2016.360 Abstract | Full Text | | | | Inflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosisXiao-Ming Meng, Shuang Wang, Xiao-Ru Huang, Chen Yang, Jun Xiao, Yang Zhang, Ka-Fai To, David J Nikolic-Paterson and Hui-Yao Lan Cell Death Dis 2016 7: e2495; 10.1038/cddis.2016.402 Abstract | Full Text | | | | Preimplantation factor is an anti-apoptotic effector in human trophoblasts involving p53 signaling pathwayHadia Moindjie, Esther Dos Santos, Rita-Josiane Gouesse, Nelly Swierkowski-Blanchard, Valérie Serazin, Eytan R Barnea, François Vialard and Marie-Noëlle Dieudonné Cell Death Dis 2016 7: e2504; 10.1038/cddis.2016.382 Abstract | Full Text | | | | Non-amyloidogenic effects of α2 adrenergic agonists: implications for brimonidine-mediated neuroprotectionShereen Nizari, Li Guo, Benjamin M Davis, Eduardo M Normando, Joana Galvao, Lisa A Turner, Mukhtar Bizrah, Mohammad Dehabadi, Kailin Tian and M Francesca Cordeiro Cell Death Dis 2016 7: e2514; 10.1038/cddis.2016.397 Abstract | Full Text | | | | Phosphorylated STAT5 regulates p53 expression via BRCA1/BARD1-NPM1 and MDM2Zhuo Ren, Joeri L Aerts, Hugo Vandenplas, Jiance A Wang, Olena Gorbenko, Jack P Chen, Philippe Giron, Carlo Heirman, Cleo Goyvaerts, Eldad Zacksenhaus, Mark D Minden, Vuk Stambolic, Karine Breckpot and Jacques De Grève Cell Death Dis 2016 7: e2560; 10.1038/cddis.2016.430 Abstract | Full Text | | | | Distinct outcomes of CRL–Nedd8 pathway inhibition reveal cancer cell plasticityAnastasia V Rulina, Frédérique Mittler, Patricia Obeid, Sophie Gerbaud, Laurent Guyon, Eric Sulpice, Frédérique Kermarrec, Nicole Assard, Monika E Dolega, Xavier Gidrol and Maxim Y Balakirev Cell Death Dis 2016 7: e2505; 10.1038/cddis.2016.395 Abstract | Full Text | | | | A mechanism for overcoming P-glycoprotein-mediated drug resistance: novel combination therapy that releases stored doxorubicin from lysosomes via lysosomal permeabilization using Dp44mT or DpCNicole A Seebacher, Des R Richardson and Patric J Jansson Cell Death Dis 2016 7: e2510; 10.1038/cddis.2016.381 Abstract | Full Text | | | | Human umbilical cord blood-stem cells direct macrophage polarization and block inflammasome activation to alleviate rheumatoid arthritisTae-Hoon Shin, Hyung-Sik Kim, Tae-Wook Kang, Byung-Chul Lee, Hwa-Yong Lee, Yoon-Jin Kim, Ji-Hee Shin, Yoojin Seo, Soon Won Choi, Seunghee Lee, Kichul Shin, Kwang-Won Seo and Kyung-Sun Kang Cell Death Dis 2016 7: e2524; 10.1038/cddis.2016.442 Abstract | Full Text | | | | Hyperhomocysteinemia causes ER stress and impaired autophagy that is reversed by Vitamin B supplementationMadhulika Tripathi, Cheng Wu Zhang, Brijesh Kumar Singh, Rohit Anthony Sinha, Kyaw Thu Moe, Deidre Anne DeSilva and Paul Michael Yen Cell Death Dis 2016 7: e2513; 10.1038/cddis.2016.374 Abstract | Full Text | | | | miR-148a-3p represses proliferation and EMT by establishing regulatory circuits between ERBB3/AKT2/c-myc and DNMT1 in bladder cancerXiao Wang, Zhen Liang, Xin Xu, Jiangfeng Li, Yi Zhu, Shuai Meng, Shiqi Li, Song Wang, Bo Xie, Alin Ji, Ben Liu, Xiangyi Zheng and Liping Xie Cell Death Dis 2016 7: e2503; 10.1038/cddis.2016.373 Abstract | Full Text | | | | Upregulation of MiR-205 under hypoxia promotes epithelial–mesenchymal transition by targeting ASPP2Xingwen Wang, Miao Yu, Kunming Zhao, Mengmeng He, Wenjie Ge, Yuhui Sun, Yihua Wang, Haizhu Sun and Ying Hu Cell Death Dis 2016 7: e2517; 10.1038/cddis.2016.412 Abstract | Full Text | | | | 1-Methyl-tryptophan attenuates regulatory T cells differentiation due to the inhibition of estrogen-IDO1-MRC2 axis in endometriosisChunyan Wei, Jie Mei, Lingli Tang, Yukai Liu, Dajin Li, Mingqing Li and Xiaoyong Zhu Cell Death Dis 2016 7: e2489; 10.1038/cddis.2016.375 Abstract | Full Text | | | | The Yersinia Type III secretion effector YopM Is an E3 ubiquitin ligase that induced necrotic cell death by targeting NLRP3Congwen Wei, Ying Wang, Zongmin Du, Kai Guan, Ye Cao, Huiying Yang, Pengyu Zhou, Feixiang Wu, Jiankang Chen, Penghao Wang, Zirui Zheng, Pingping Zhang, Yanhong Zhang, Shengli Ma, Ruifu Yang, Hui Zhong and Xiang He Cell Death Dis 2016 7: e2519; 10.1038/cddis.2016.413 Abstract | Full Text | | | | Downregulated expression of microRNA-124 in pediatric intestinal failure patients modulates macrophages activation by inhibiting STAT3 and AChEYong-Tao Xiao, Jun Wang, Wei Lu, Yi Cao and Wei Cai Cell Death Dis 2016 7: e2521; 10.1038/cddis.2016.426 Abstract | Full Text | | | | Rab17 mediates differential antigen sorting following efferocytosis and phagocytosisCharles Yin, Yohan Kim, Dean Argintaru and Bryan Heit Cell Death Dis 2016 7: e2529; 10.1038/cddis.2016.431 Abstract | Full Text | | | | Smad3-related miRNAs regulated oncogenic TRIB2 promoter activity to effectively suppress lung adenocarcinoma growthYan-Xia Zhang, Yun-Fei Yan, Yue-Mei Liu, You-Jie Li, Han-Han Zhang, Min Pang, Jin-Xia Hu, Wei Zhao, Ning Xie, Ling Zhou, Ping-Yu Wang and Shu-Yang Xie Cell Death Dis 2016 7: e2528; 10.1038/cddis.2016.432 Abstract | Full Text | | | | Rab8a/Rab11a regulate intercellular communications between neural cells via tunneling nanotubesHui Zhu, Chengbin Xue, Xi Xu, Yibing Guo, Xiaohong Li, Jingjing Lu, Shaoqing Ju, Yongjun Wang, Zheng Cao and Xiaosong Gu Cell Death Dis 2016 7: e2523; 10.1038/cddis.2016.441 Abstract | Full Text | | | | PINK1-dependent phosphorylation of PINK1 and Parkin is essential for mitochondrial quality controlNa Zhuang, Lin Li, She Chen and Tao Wang Cell Death Dis 2016 7: e2501; 10.1038/cddis.2016.396 Abstract | Full Text | | Correspondence | Top | | Male sterility in Mcl-1-flox mice is not due to enhanced Mcl1 protein stabilityCasey Ah-Cann, Maximilien Tailler, Andrew J Kueh, Marco J Herold, Joseph T Opferman, Marie-Liesse Asselin-Labat and Philippe Bouillet Cell Death Dis 2016 7: e2490; 10.1038/cddis.2016.391 Full Text | | | | | Advertisement | | Oncogenesis is an online-only, open access journal exploring the molecular basis of cancer and related phenomena. The journal seeks to promote diverse and integrated areas of molecular biology, cell biology, oncology, and genetics.
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