Molecular Systems Biology - New articles published - 1 Apr 2016

March 2016 | Volume 12, Number 3 Submit Table of Contents Articles Volume 12, Number 3 Articles Integrative analyses reveal signaling pathways underlying familial breast cancer susceptibility A pathway‐based integrative analysis of genomic and transcriptomic datasets and follow‐up experimental validations indicate the dysregulation of cell adhesion pathways in women at high risk for familial breast cancer. Stephen R Piccolo, Laura M Hoffman, Thomas Conner, Gajendra Shrestha, Adam L Cohen, Jeffrey R Marks, Leigh A Neumayer, Cori A Agarwal, Mary C Beckerle, Irene L Andrulis, Avrum E Spira, Philip J Moos, Saundra S Buys, William Evan Johnson, and Andrea H Bild Published online 10.03.2016 Environment‐induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children Genome‐wide epigenomic and transcriptomic data reveal that maternal smoking induces important changes in the methylome of mothers and their children that affect in particular enhancer regions. These changes are stably maintained for years in the epigenome of the child. Tobias Bauer, Saskia Trump, Naveed Ishaque, Loreen Thürmann, Lei Gu, Mario Bauer, Matthias Bieg, Zuguang Gu, Dieter Weichenhan, Jan‐Philipp Mallm, Stefan Röder, Gunda Herberth, Eiko Takada, Oliver Mücke, Marcus Winter, Kristin M Junge, Konrad Grützmann, Ulrike Rolle‐Kampczyk, Qi Wang, Christian Lawerenz, Michael Borte, Tobias Polte, Matthias Schlesner, Michaela Schanne, Stefan Wiemann, Christina Geörg, Hendrik G Stunnenberg, Christoph Plass, Karsten Rippe, Junichiro Mizuguchi, Carl Herrmann, Roland Eils, and Irina Lehmann Published online 24.03.2016   Unsubscribe from or edit your subscription for this service. Or by mail: Customer Service * 425 Broadway St * Redwood City, CA 94063 * U.S.A. Copyright © 2016 by the European Molecular Biology Organisation.