Molecular Therapy - Methods & Clinical Development: now indexed in PubMed and PubMed Central
An online-only, open access journal publishing top-quality, novel methods and technology development, as well as significant improvements to established research techniques in basic, translational, and clinical cell and gene therapy.
Explore the benefits of submitting your next manuscript. |  | | |  | | Editorial | Top |  | Gene Therapy for Heart Failure: Back to the BenchSeppo Ylä-Herttuala Mol Ther 2015 23: 1551-1552; 10.1038/mt.2015.158 Full Text |  | In This Issue | Top |  | In This IssueMol Ther 2015 23: 1554; 10.1038/mt.2015.159 Full Text |  | Research Highlights | Top |  | Research HighlightsMol Ther 2015 23: 1555; 10.1038/mt.2015.160 Full Text |  | Commentaries | Top |  | Emerging Roles of tRNA-derived Fragments in Viral Infections: The Case of Respiratory Syncytial VirusPavel Ivanov Mol Ther 2015 23: 1557-1558; 10.1038/mt.2015.161 Full Text |  |  |  | Strain-dependent Lethal Toxicity in NKG2D Ligand-targeted CAR T-cell TherapyRachel C Lynn and Daniel J Powell, Jr Mol Ther 2015 23: 1559-1561; 10.1038/mt.2015.162 Full Text |  | Original Articles | Top |  | Optogenetic Vision Restoration Using Rhodopsin for Enhanced SensitivityMTOPENBenjamin M Gaub, Michael H Berry, Amy E Holt, Ehud Y Isacoff and John G Flannery Mol Ther 2015 23: 1562-1571; advance online publication, July 3, 2015; 10.1038/mt.2015.121 Abstract | Full Text |  |  |  | Benefits of Neuronal Preferential Systemic Gene Therapy for Neurotransmitter DeficiencyNi-Chung Lee, Shin-Ichi Muramatsu, Yin-Hsiu Chien, Wen-Shin Liu, Wei-Hua Wang, Chia-Hao Cheng, Meng-Kai Hu, Pin-Wen Chen, Kai-Yuan Tzen, Barry J Byrne and Wuh-Liang Hwu Mol Ther 2015 23: 1572-1581; advance online publication, July 3, 2015; 10.1038/mt.2015.122 Abstract | Full Text |  |  |  | Riboswitch-mediated Attenuation of Transgene Cytotoxicity Increases Adeno-associated Virus Vector Yields in HEK-293 CellsBenjamin Strobel, Benedikt Klauser, Jörg S Hartig, Thorsten Lamla, Florian Gantner and Sebastian Kreuz Mol Ther 2015 23: 1582-1591; advance online publication, July 3, 2015; 10.1038/mt.2015.123 Abstract | Full Text |  |  |  | MitoTALEN: A General Approach to Reduce Mutant mtDNA Loads and Restore Oxidative Phosphorylation Function in Mitochondrial DiseasesMasami Hashimoto, Sandra R Bacman, Susana Peralta, Marni J Falk, Anne Chomyn, David C Chan, Sion L Williams and Carlos T Moraes Mol Ther 2015 23: 1592-1599; advance online publication, July 10, 2015; 10.1038/mt.2015.126 Abstract | Full Text |  |  |  | T Cells Engineered With Chimeric Antigen Receptors Targeting NKG2D Ligands Display Lethal Toxicity in MiceHeather VanSeggelen, Joanne A Hammill, Anna Dvorkin-Gheva, Daniela GM Tantalo, Jacek M Kwiecien, Galina F Denisova, Brian Rabinovich, Yonghong Wan and Jonathan L Bramson Mol Ther 2015 23: 1600-1610; advance online publication, June 30, 2015; 10.1038/mt.2015.119 Abstract | Full Text |  |  |  | Dual TNF-α/IL-12p40 Interference as a Strategy to Protect Against Colitis Based on miR-16 Precursors With Macrophage Targeting VectorsZhen Huang, Junting Ma, Mengjie Chen, Haoyang Jiang, Yong Fu, Jingjing Gan, Lei Dong, Junfeng Zhang and Jiangning Chen Mol Ther 2015 23: 1611-1621; advance online publication, June 15, 2015; 10.1038/mt.2015.111 Abstract | Full Text |  |  |  | Respiratory Syncytial Virus Utilizes a tRNA Fragment to Suppress Antiviral Responses Through a Novel Targeting MechanismJunfang Deng, Ryan N Ptashkin, Yu Chen, Zhi Cheng, Guangliang Liu, Thien Phan, Xiaoling Deng, Jiehua Zhou, Inhan Lee, Yong Sun Lee and Xiaoyong Bao Mol Ther 2015 23: 1622-1629; advance online publication, July 9, 2015; 10.1038/mt.2015.124 Abstract | Full Text |  |  |  | Viral Infection of Tumors Overcomes Resistance to PD-1-immunotherapy by Broadening Neoantigenome-directed T-cell ResponsesNorman Woller, Engin Gürlevik, Bettina Fleischmann-Mundt, Anja Schumacher, Sarah Knocke, Arnold M Kloos, Michael Saborowski, Robert Geffers, Michael P Manns, Thomas C Wirth, Stefan Kubicka and Florian Kühnel Mol Ther 2015 23: 1630-1640; advance online publication, June 26, 2015; 10.1038/mt.2015.115 Abstract | Full Text |  |  |  | Biodistribution Analysis of Oncolytic Adenoviruses in Patient Autopsy Samples Reveals Vascular Transduction of Noninjected Tumors and TissuesAnniina Koski, Simona Bramante, Anja Kipar, Minna Oksanen, Juuso Juhila, Lotta Vassilev, Timo Joensuu, Anna Kanerva and Akseli Hemminki Mol Ther 2015 23: 1641-1652; advance online publication, July 9, 2015; 10.1038/mt.2015.125 Abstract | Full Text |  |  |  | Ubiquitin-like Molecule ISG15 Acts as an Immune Adjuvant to Enhance Antigen-specific CD8 T-cell Tumor ImmunityDaniel O Villarreal, Megan C Wise, Rebekah J Siefert, Jian Yan, Laurence M Wood and David B Weiner Mol Ther 2015 23: 1653-1662; advance online publication, June 30, 2015; 10.1038/mt.2015.120 Abstract | Full Text |  |  |  | Human Rhinovirus Presenting 4E10 Epitope of HIV-1 MPER Elicits Neutralizing Antibodies in Human ICAM-1 Transgenic MiceGuohua Yi, Xiongying Tu, Preeti Bharaj, Hua Guo, Junli Zhang, Premlata Shankar and N Manjunath Mol Ther 2015 23: 1663-1670; advance online publication, June 10, 2015; 10.1038/mt.2015.107 Abstract | Full Text |  | Erratum | Top |  | Erratum to “Hyperactive PiggyBac Transposons for Sustained and Robust Liver-targeted Gene Therapy”Mol Ther 2015 23: 1671; advance online publication, July 28, 2015; 10.1038/mt.2015.132 Full Text |  |  |  | Please note that you need to be a subscriber or site-license holder to enjoy full-text access to Molecular Therapy. 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