Genetics in Medicine contents: Volume 17, Issue 6

TABLE OF CONTENTS Volume 17, Issue 6 (June 2015) In this issue Research Highlights Systematic Review Commentary Review Original Research Article Brief Report ACMG Policy Statement Letter to the Editor Genetic Legacy Corrigendum Erratum Podcast Facebook Twitter Subscribe Recommend to your library RSS ACMG Advertisement Web Focus: Genetics and Gastrointestinal Diseases Genetics and genomics are beginning to strongly influence the care of patients with GI conditions. This web focus brings together seminal articles exploring new genomic findings in clinical practice that have been published in Genetics in Medicine, The American Journal of Gastroenterology and Clinical and Translational Gastroenterology. Access the focus online.    Research Highlights Top In this Issue Genet Med 2015 17: 429; 10.1038/gim.2015.66 Full Text News Briefs Genet Med 2015 17: 429-430; 10.1038/gim.2015.77 Full Text Systematic Review Top An overview of recommendations and translational milestones for genomic tests in cancer Christine Q. Chang, Sharna R. Tingle, Kelly K. Filipski, Muin J. Khoury, Tram Kim Lam, Sheri D. Schully and John P.A. Ioannidis Genet Med 2015 17: 431-440; advance online publication, October 23, 2014; 10.1038/gim.2014.133 Abstract | Full Text Commentary Top Genomic screening of the general adult population: key concepts for assessing net benefit with systematic evidence reviews Anya E.R. Prince, Jonathan S. Berg, James P. Evans, Daniel E. Jonas and Gail Henderson Genet Med 2015 17: 441-443; advance online publication, September 18, 2014; 10.1038/gim.2014.129 Full Text Review Top Solving the molecular diagnostic testing conundrum for Mendelian disorders in the era of next-generation sequencing: single-gene, gene panel, or exome/genome sequencing Yuan Xue, Arunkanth Ankala, William R. Wilcox and Madhuri R. Hegde Genet Med 2015 17: 444-451; advance online publication, September 18, 2014; 10.1038/gim.2014.122 Abstract | Full Text Original Research Articles Top Mortality of New York children with sickle cell disease identified through newborn screening Ying Wang, Gang Liu, Michele Caggana, Joseph Kennedy, Regina Zimmerman, Suzette O. Oyeku, Ellen M. Werner, Althea M. Grant, Nancy S. Green and Scott D. Grosse Genet Med 2015 17: 452-459; advance online publication, September 25, 2014; 10.1038/gim.2014.123 Abstract | Full Text Refinement of the critical 2p25.3 deletion region: the role of MYT1L in intellectual disability and obesity Nina De Rocker, Sarah Vergult, David Koolen, Eva Jacobs, Alexander Hoischen, Susan Zeesman, Birgitte Bang, Frédérique Béna, Nele Bockaert, Ernie M. Bongers, Thomy de Ravel, Koenraad Devriendt, Sabrina Giglio, Laurence Faivre, Shelagh Joss, Saskia Maas, Nathalie Marle, Francesca Novara, Malgorzata J.M. Nowaczyk, Hilde Peeters, Abeltje Polstra, Filip Roelens, Carla Rosenberg, Julien Thevenon, Zeynep Tümer, Suzanne Vanhauwaert, Konstantinos Varvagiannis, Andy Willaert, Marjolein Willemsen, Marjolaine Willems, Orsetta Zuffardi, Paul Coucke, Frank Speleman, Evan E. Eichler, Tjitske Kleefstra and Björn Menten Genet Med 2015 17: 460-466; advance online publication, September 18, 2014; 10.1038/gim.2014.124 Abstract | Full Text Disparities in uptake of BRCA1/2 genetic testing in a randomized trial of telephone counseling OPEN Morgan Butrick, Scott Kelly, Beth N. Peshkin, George Luta, Rachel Nusbaum, Gillian W. Hooker, Kristi Graves, Lisa Feeley, Claudine Isaacs, Heiddis B. Valdimarsdottir, Lina Jandorf, Tiffani DeMarco, Marie Wood, Wendy McKinnon, Judy Garber, Shelley R. McCormick and Marc D. Schwartz Genet Med 2015 17: 467-475; advance online publication, September 18, 2014; 10.1038/gim.2014.125 Abstract | Full Text Is it all Lynch syndrome?: An assessment of family history in individuals with mismatch repair–deficient tumors Katherine M. Dempsey, Russell Broaddus, Y. Nancy You, Sarah Jane Noblin, Maureen Mork, Bryan Fellman, Diana Urbauer, Molly Daniels and Karen Lu Genet Med 2015 17: 476-484; advance online publication, October 23, 2014; 10.1038/gim.2014.131 Abstract | Full Text Development of a tiered and binned genetic counseling model for informed consent in the era of multiplex testing for cancer susceptibility Angela R. Bradbury, Linda Patrick-Miller, Jessica Long, Jacquelyn Powers, Jill Stopfer, Andrea Forman, Christina Rybak, Kristin Mattie, Amanda Brandt, Rachelle Chambers, Wendy K. Chung, Jane Churpek, Mary B. Daly, Laura Digiovanni, Dana Farengo-Clark, Dominique Fetzer, Pamela Ganschow, Generosa Grana, Cassandra Gulden, Michael Hall, Lynne Kohler, Kara Maxwell, Shana Merrill, Susan Montgomery, Rebecca Mueller, Sarah Nielsen, Olufunmilayo Olopade, Kimberly Rainey, Christina Seelaus, Katherine L. Nathanson and Susan M. Domchek Genet Med 2015 17: 485-492; advance online publication, October 9, 2014; 10.1038/gim.2014.134 Abstract | Full Text Clinically relevant lessons from Family HealthLink: a cancer and coronary heart disease familial risk assessment tool Kevin Sweet, Amy C. Sturm, Amy Rettig, Joseph McElroy and Doreen Agnese Genet Med 2015 17: 493-500; advance online publication, October 30, 2014; 10.1038/gim.2014.136 Abstract | Full Text Brief Report Top Parents are interested in newborn genomic testing during the early postpartum period Susan E. Waisbren, Danielle K. Bäck, Christina Liu, Sarah S. Kalia, Steven A. Ringer, Ingrid A. Holm and Robert C. Green Genet Med 2015 17: 501-504; advance online publication, December 4, 2014; 10.1038/gim.2014.139 Abstract | Full Text ACMG Policy Statement Top Clinical utility of genetic and genomic services: a position statement of the American College of Medical Genetics and Genomics ACMG Board of Directors1 Genet Med 2015 17: 505-507; advance online publication, March 12, 2015; 10.1038/gim.2015.41 Abstract | Full Text Letter to the Editor Top The challenge of defining pathogenicity: the example of AHI1 Raoul Heller and Hanno J. Bolz Genet Med 2015 17: 508; 10.1038/gim.2015.46 Full Text Response to Heller and Bolz Zi-Bing Jin and Xiu-Feng Huang Genet Med 2015 17: 508-509; 10.1038/gim.2015.48 Full Text The cost-effectiveness of routine testing for Lynch syndrome in newly diagnosed patients with colorectal cancer in the United States: corrected estimates Scott D. Grosse, Glenn E. Palomaki, Mercy Mvundura and Heather Hampel Genet Med 2015 17: 510-511; 10.1038/gim.2015.53 Full Text Genetic Legacy Top Reproducing Genetics Joe Leigh Simpson Genet Med 2015 17: 512-514; 10.1038/gim.2015.37 Full Text Corrigendum Top CORRIGENDUM: Too much, too soon?: Commercial provision of noninvasive prenatal screening for subchromosomal abnormalities and beyond Genet Med 2015 17: 515; 10.1038/gim.2015.64 Full Text Erratum Top ERRATUM: A genome sequencing program for novel undiagnosed diseases Genet Med 2015 17: 515; 10.1038/gim.2015.63 Full Text Podcast Top Listen to the latest podcast here. Advertisement Genomic advances are revolutionizing our understanding of oncology. Over the past year, Genetics in Medicine has published articles of great relevance to oncologists and their patients, spanning the spectrum from rare cancers to common malignancies. In the new Focus on Oncology, the editors have selected pertinent articles that will be useful for practitioners in the field.     You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/nams/svc/myaccount (You will need to log in to be recognised as a nature.com registrant). For further technical assistance, please contact our registration department. For other enquiries, please contact our customer feedback department. Nature Publishing Group | 75 Varick Street, 9th Floor | New York | NY 10013-1917 | USA Nature Publishing Group's worldwide offices: London - Paris - Munich - New Delhi - Tokyo - Melbourne San Diego - San Francisco - Washington - New York - Boston Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at Brunel Road, Houndmills, Basingstoke, Hampshire RG21 6XS. © 2015 Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.