Advertisement |  | | |  | TABLE OF CONTENTS
| June 2015 Volume 47, Issue 6 |  | | |  |  Editorial
News and Views
Research Highlights
Analysis
Brief Communications
Articles
Letters
Technical Report
Erratum
Corrigenda
| | | | | | | Advertisement | | Nature Communications is now fully open access
All new submissions if accepted, will be published open access and an article processing charge will apply. For more information visit the website.
Visit our open access funding page or contact openaccess@nature.com to learn more on APC funding. | | | | | | | Editorial |  Top | |  | | Call for crop improvement Analysis articles p561
doi:10.1038/ng.3334
We offer to publish Analyses of genomic and phenotypic data that present new concepts and strategies for the improvement of crop plant yield and nutritional value via the introduction, selection and use of genetic variation within the context of changes in markets, climate, water use and agronomic practices.
| | News and Views | Top | | | | | | Research Highlights | Top | | | | Heterochromatin and human aging | Fibrogenic lineage identified | Spermatogenic signaling through Rarg | Modeling NOTCH1 haploinsufficiency | Regulatory rewiring | Analysis | Top | | | | Understanding multicellular function and disease with human tissue-specific networks pp569 - 576
Casey S Greene, Arjun Krishnan, Aaron K Wong, Emanuela Ricciotti, Rene A Zelaya, Daniel S Himmelstein, Ran Zhang, Boris M Hartmann, Elena Zaslavsky, Stuart C Sealfon, Daniel I Chasman, Garret A FitzGerald, Kara Dolinski, Tilo Grosser & Olga G Troyanskaya
doi:10.1038/ng.3259
Olga Troyanskaya and colleagues present genome-wide functional interaction networks for 144 human tissues and cell types. They identify important disease-gene associations by combining data from GWAS and tissue-specific networks. They also developed a webserver, GIANT, that includes multi-gene query capability, network visualization and analysis tools.
| | Brief Communications | Top | | | | Fine mapping in the MHC region accounts for 18% additional genetic risk for celiac disease pp577 - 578
Javier Gutierrez-Achury, Alexandra Zhernakova, Sara L Pulit, Gosia Trynka, Karen A Hunt, Jihane Romanos, Soumya Raychaudhuri, David A van Heel, Cisca Wijmenga & Paul I W de Bakker
doi:10.1038/ng.3268
Cisca Wijmenga and colleagues report fine mapping of the association signal in the MHC region in individuals with celiac disease. They identify five additional risk factors that are independent of HLA-DQ alleles and that account for 18% of the genetic risk for this disease.
| | | | Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export pp579 - 581
Andrea Legati, Donatella Giovannini, Gaël Nicolas, Uriel López-Sánchez, Beatriz Quintáns, João R M Oliveira, Renee L Sears, Eliana Marisa Ramos, Elizabeth Spiteri, María-Jesús Sobrido, Ángel Carracedo, Cristina Castro-Fernández, Stéphanie Cubizolle, Brent L Fogel, Cyril Goizet, Joanna C Jen, Suppachok Kirdlarp, Anthony E Lang, Zosia Miedzybrodzka, Witoon Mitarnun, Martin Paucar, Henry Paulson, Jérémie Pariente, Anne-Claire Richard, Naomi S Salins, Sheila A Simpson, Pasquale Striano, Per Svenningsson, François Tison, Vivek K Unni, Olivier Vanakker, Marja W Wessels, Suppachok Wetchaphanphesat, Michele Yang, Francois Boller, Dominique Campion, Didier Hannequin, Marc Sitbon, Daniel H Geschwind, Jean-Luc Battini & Giovanni Coppola
doi:10.1038/ng.3289
Jean-Luc Battini, Giovanni Coppola and colleagues identify XPR1 mutations in several families with primary brain calcification. They further show that these mutations alter phosphate export activity, implicating defective phosphate homeostasis in the etiology of this disease.
| | Articles | Top | | | | Excess of rare, inherited truncating mutations in autism pp582 - 588
Niklas Krumm, Tychele N Turner, Carl Baker, Laura Vives, Kiana Mohajeri, Kali Witherspoon, Archana Raja, Bradley P Coe, Holly A Stessman, Zong-Xiao He, Suzanne M Leal, Raphael Bernier & Evan E Eichler
doi:10.1038/ng.3303
Evan Eichler and colleagues analyze the relative impact of de novo and rare, inherited variants on autism risk. They show a statistically independent role for rare, inherited mutations and implicate several new candidate genes likely contributing to autism risk.
| | | | The impact of low-frequency and rare variants on lipid levels pp589 - 597
Ida Surakka, Momoko Horikoshi, Reedik Mägi, Antti-Pekka Sarin, Anubha Mahajan, Vasiliki Lagou, Letizia Marullo, Teresa Ferreira, Benjamin Miraglio, Sanna Timonen, Johannes Kettunen, Matti Pirinen, Juha Karjalainen, Gudmar Thorleifsson, Sara Hägg, Jouke-Jan Hottenga, Aaron Isaacs, Claes Ladenvall, Marian Beekman, Tõnu Esko, Janina S Ried, Christopher P Nelson, Christina Willenborg, Stefan Gustafsson, Harm-Jan Westra, Matthew Blades, Anton J M de Craen, Eco J de Geus, Joris Deelen, Harald Grallert, Anders Hamsten, Aki S Havulinna, Christian Hengstenberg, Jeanine J Houwing-Duistermaat, Elina Hyppönen, Lennart C Karssen, Terho Lehtimäki, Valeriya Lyssenko, Patrik K E Magnusson, Evelin Mihailov, Martina Müller-Nurasyid, John-Patrick Mpindi, Nancy L Pedersen, Brenda W J H Penninx, Markus Perola, Tune H Pers, Annette Peters, Johan Rung, Johannes H Smit, Valgerdur Steinthorsdottir, Martin D Tobin, Natalia Tsernikova, Elisabeth M van Leeuwen, Jorma S Viikari, Sara M Willems, Gonneke Willemsen, Heribert Schunkert, Jeanette Erdmann, Nilesh J Samani, Jaakko Kaprio, Lars Lind, Christian Gieger, Andres Metspalu, P Eline Slagboom, Leif Groop, Cornelia M van Duijn, Johan G Eriksson, Antti Jula, Veikko Salomaa, Dorret I Boomsma, Christine Power, Olli T Raitakari, Erik Ingelsson, Marjo-Riitta Järvelin, Unnur Thorsteinsdottir, Lude Franke, Elina Ikonen, Olli Kallioniemi, Vilja Pietiäinen, Cecilia M Lindgren, Kari Stefansson, Aarno Palotie, Mark I McCarthy, Andrew P Morris, Inga Prokopenko, Samuli Ripatti & ENGAGE Consortium
doi:10.1038/ng.3300
Samuli Ripatti and colleagues report the results of a genome-wide association study for circulating lipid levels based on 1000 Genomes Project imputation. Their results implicate several new loci, refine the association signals at many established loci and highlight the impact of low-frequency variants on lipid traits.
| | | | Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C pp598 - 606
Borbala Mifsud, Filipe Tavares-Cadete, Alice N Young, Robert Sugar, Stefan Schoenfelder, Lauren Ferreira, Steven W Wingett, Simon Andrews, William Grey, Philip A Ewels, Bram Herman, Scott Happe, Andy Higgs, Emily LeProust, George A Follows, Peter Fraser, Nicholas M Luscombe & Cameron S Osborne
doi:10.1038/ng.3286
Nicholas Luscombe, Cameron Osborne and colleagues report the use of Capture Hi-C (CHi-C) to detect the long-range interactions of almost 22,000 promoters in 2 human cell types. They found that transcriptionally inactive genes interact with previously uncharacterized elements that may act as long-range silencers.
| | | | NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells pp607 - 614
Steven W Paugh, Erik J Bonten, Daniel Savic, Laura B Ramsey, William E Thierfelder, Prajwal Gurung, R K Subbarao Malireddi, Marcelo Actis, Anand Mayasundari, Jaeki Min, David R Coss, Lucas T Laudermilk, John C Panetta, J Robert McCorkle, Yiping Fan, Kristine R Crews, Gabriele Stocco, Mark R Wilkinson, Antonio M Ferreira, Cheng Cheng, Wenjian Yang, Seth E Karol, Christian A Fernandez, Barthelemy Diouf, Colton Smith, J Kevin Hicks, Alessandra Zanut, Audrey Giordanengo, Daniel Crona, Joy J Bianchi, Linda Holmfeldt, Charles G Mullighan, Monique L den Boer, Rob Pieters, Sima Jeha, Thomas L Dunwell, Farida Latif, Deepa Bhojwani, William L Carroll, Ching-Hon Pui, Richard M Myers, R Kiplin Guy, Thirumala-Devi Kanneganti, Mary V Relling & William E Evans
doi:10.1038/ng.3283
William Evans and colleagues find that the proinflammatory genes CASP1 and NLRP3 are expressed at higher levels in primary acute lymphoblastic leukemia cells that are resistant than in those that are sensitive to glucocorticoid treatment. They find that CASP1 mediates glucocorticoid resistance through cleavage of the glucocorticoid receptor.
| | | | A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis pp615 - 624
Branden S Moriarity, George M Otto, Eric P Rahrmann, Susan K Rathe, Natalie K Wolf, Madison T Weg, Luke A Manlove, Rebecca S LaRue, Nuri A Temiz, Sam D Molyneux, Kwangmin Choi, Kevin J Holly, Aaron L Sarver, Milcah C Scott, Colleen L Forster, Jaime F Modiano, Chand Khanna, Stephen M Hewitt, Rama Khokha, Yi Yang, Richard Gorlick, Michael A Dyer & David A Largaespada
doi:10.1038/ng.3293
Branden Moriarity, David Largaespada and colleagues report a Sleeping Beauty forward genetic screen in mice that identifies candidate genes and pathways for osteosarcoma tumor development and progression. They identify sites specifically associated with tumorigenesis and metastasis and find that several candidate oncogenes are involved in axon guidance.
See also: News and Views by Jones | | | | The draft genome of the grass carp (Ctenopharyngodon idellus) provides insights into its evolution and vegetarian adaptation OPEN pp625 - 631
Yaping Wang, Ying Lu, Yong Zhang, Zemin Ning, Yan Li, Qiang Zhao, Hengyun Lu, Rong Huang, Xiaoqin Xia, Qi Feng, Xufang Liang, Kunyan Liu, Lei Zhang, Tingting Lu, Tao Huang, Danlin Fan, Qijun Weng, Chuanrang Zhu, Yiqi Lu, Wenjun Li, Ziruo Wen, Congcong Zhou, Qilin Tian, Xiaojun Kang, Mijuan Shi, Wanting Zhang, Songhun Jang, Fukuan Du, Shan He, Lanjie Liao, Yongming Li, Bin Gui, Huihui He, Zhen Ning, Cheng Yang, Libo He, Lifei Luo, Rui Yang, Qiong Luo, Xiaochun Liu, Shuisheng Li, Wen Huang, Ling Xiao, Haoran Lin, Bin Han & Zuoyan Zhu
doi:10.1038/ng.3280
Bin Han and colleagues report the draft genome sequence of the grass carp Ctenopharyngodon idellus, a major commercially farmed species of freshwater fish. Analyses of the grass carp genome identify lineage-specific duplications that may have contributed to the adaptation of this species to a vegetarian diet.
| | | | Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events pp632 - 639
Vanessa K Wong, Stephen Baker, Derek J Pickard, Julian Parkhill, Andrew J Page, Nicholas A Feasey, Robert A Kingsley, Nicholas R Thomson, Jacqueline A Keane, François-Xavier Weill, David J Edwards, Jane Hawkey, Simon R Harris, Alison E Mather, Amy K Cain, James Hadfield, Peter J Hart, Nga Tran Vu Thieu, Elizabeth J Klemm, Dafni A Glinos, Robert F Breiman, Conall H Watson, Samuel Kariuki, Melita A Gordon, Robert S Heyderman, Chinyere Okoro, Jan Jacobs, Octavie Lunguya, W John Edmunds, Chisomo Msefula, Jose A Chabalgoity, Mike Kama, Kylie Jenkins, Shanta Dutta, Florian Marks, Josefina Campos, Corinne Thompson, Stephen Obaro, Calman A MacLennan, Christiane Dolecek, Karen H Keddy, Anthony M Smith, Christopher M Parry, Abhilasha Karkey, E Kim Mulholland, James I Campbell, Sabina Dongol, Buddha Basnyat, Muriel Dufour, Don Bandaranayake, Take Toleafoa Naseri, Shalini Pravin Singh, Mochammad Hatta, Paul Newton, Robert S Onsare, Lupeoletalalei Isaia, David Dance, Viengmon Davong, Guy Thwaites, Lalith Wijedoru, John A Crump, Elizabeth De Pinna, Satheesh Nair, Eric J Nilles, Duy Pham Thanh, Paul Turner, Sona Soeng, Mary Valcanis, Joan Powling, Karolina Dimovski, Geoff Hogg, Jeremy Farrar, Kathryn E Holt & Gordon Dougan
doi:10.1038/ng.3281
Vanessa Wong and colleagues report whole-genome sequencing of 1,832 Salmonella enterica serovar Typhi isolates from 63 endemic countries. They identify mutations that define the multidrug resistant (MDR) H58 lineage and report numerous inter- and intracontinental transmissions of this lineage as well as an ongoing MDR typhoid epidemic in Africa.
See also: News and Views by Wirth | | Letters | Top | | | | Analysis of loss-of-function variants and 20 risk factor phenotypes in 8,554 individuals identifies loci influencing chronic disease pp640 - 642
Alexander H Li, Alanna C Morrison, Christie Kovar, L Adrienne Cupples, Jennifer A Brody, Linda M Polfus, Bing Yu, Ginger Metcalf, Donna Muzny, Narayanan Veeraraghavan, Xiaoming Liu, Thomas Lumley, Thomas H Mosley, Richard A Gibbs & Eric Boerwinkle
doi:10.1038/ng.3270
Eric Boerwinkle and colleagues carried out exome sequencing on 8,554 individuals and tested loss-of-function variants for association with 20 phenotypes related to common chronic diseases. They identified several new associations and illustrate the value of applying exome sequencing to a large sample of deeply phenotyped individuals.
| | | | Germline RECQL mutations are associated with breast cancer susceptibility pp643 - 646
Cezary Cybulski, Jian Carrot-Zhang, Wojciech Kluźniak, Barbara Rivera, Aniruddh Kashyap, Dominika Wokołorczyk, Sylvie Giroux, Javad Nadaf, Nancy Hamel, Shiyu Zhang, Tomasz Huzarski, Jacek Gronwald, Tomasz Byrski, Marek Szwiec, Anna Jakubowska, Helena Rudnicka, Marcin Lener, Bartłomiej Masojć, Patrica N Tonin, Francois Rousseau, Bohdan Górski, Tadeusz Dębniak, Jacek Majewski, Jan Lubiński, William D Foulkes, Steven A Narod & Mohammad R Akbari
doi:10.1038/ng.3284
Mohammad Akbari and colleagues report that rare truncating mutations in RECQL are associated with breast cancer susceptibility. RECQL encodes a helicase that helps prevent double-stranded DNA breaks by stabilizing stalled or regressed replication forks.
| | | | PDE3A mutations cause autosomal dominant hypertension with brachydactyly pp647 - 653
Philipp G Maass, Atakan Aydin, Friedrich C Luft, Carolin Schächterle, Anja Weise, Sigmar Stricker, Carsten Lindschau, Martin Vaegler, Fatimunnisa Qadri, Hakan R Toka, Herbert Schulz, Peter M Krawitz, Dmitri Parkhomchuk, Jochen Hecht, Irene Hollfinger, Yvette Wefeld-Neuenfeld, Eireen Bartels-Klein, Astrid Mühl, Martin Kann, Herbert Schuster, David Chitayat, Martin G Bialer, Thomas F Wienker, Jürg Ott, Katharina Rittscher, Thomas Liehr, Jens Jordan, Ghislaine Plessis, Jens Tank, Knut Mai, Ramin Naraghi, Russell Hodge, Maxwell Hopp, Lars O Hattenbach, Andreas Busjahn, Anita Rauch, Fabrice Vandeput, Maolian Gong, Franz Rüschendorf, Norbert Hübner, Hermann Haller, Stefan Mundlos, Nihat Bilginturan, Matthew A Movsesian, Enno Klussmann, Okan Toka & Sylvia Bähring
doi:10.1038/ng.3302
Friedrich Luft and colleagues identify missense mutations in PDE3A in six unrelated families with an autosomal dominant syndrome marked by severe hypertension and brachydactyly. They further show that the mutations result in gain of enzymatic function, leading to increased vascular smooth muscle cell proliferation and vessel wall hyperplasia.
See also: News and Views by Houslay | | | | COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis pp654 - 660
Levi B Watkin, Birthe Jessen, Wojciech Wiszniewski, Timothy J Vece, Max Jan, Youbao Sha, Maike Thamsen, Regie L P Santos-Cortez, Kwanghyuk Lee, Tomasz Gambin, Lisa R Forbes, Christopher S Law, Asbjørg Stray-Pedersen, Mickie H Cheng, Emily M Mace, Mark S Anderson, Dongfang Liu, Ling Fung Tang, Sarah K Nicholas, Karen Nahmod, George Makedonas, Debra L Canter, Pui-Yan Kwok, John Hicks, Kirk D Jones, Samantha Penney, Shalini N Jhangiani, Michael D Rosenblum, Sharon D Dell, Michael R Waterfield, Feroz R Papa, Donna M Muzny, Noah Zaitlen, Suzanne M Leal, Claudia Gonzaga-Jauregui, Baylor-Hopkins Center for Mendelian Genomics, Eric Boerwinkle, N Tony Eissa, Richard A Gibbs, James R Lupski, Jordan S Orange & Anthony K Shum
doi:10.1038/ng.3279
Anthony Shum, Jordan Orange, James Lupski and colleagues show that mutations in the coatamer subunit gene COPA cause an autoimmune syndrome characterized by inflammatory arthritis and interstitial lung disease. They further show that the mutations disrupt ER-Golgi transport, leading to ER stress and altered T cell function.
| | | | Mutations in KCNH1 and ATP6V1B2 cause Zimmermann-Laband syndrome pp661 - 667
Fanny Kortüm, Viviana Caputo, Christiane K Bauer, Lorenzo Stella, Andrea Ciolfi, Malik Alawi, Gianfranco Bocchinfuso, Elisabetta Flex, Stefano Paolacci, Maria Lisa Dentici, Paola Grammatico, Georg Christoph Korenke, Vincenzo Leuzzi, David Mowat, Lal D V Nair, Thi Tuyet Mai Nguyen, Patrick Thierry, Susan M White, Bruno Dallapiccola, Antonio Pizzuti, Philippe M Campeau, Marco Tartaglia & Kerstin Kutsche
doi:10.1038/ng.3282
Kerstin Kutsche, Marco Tartaglia and colleagues show that missense mutations in KCNH1 and ATP6V1B2 cause Zimmermann-Laband syndrome, a disorder characterized by facial dysmorphism, intellectual disability, digit anomalies and hypertrichosis. Functional studies indicate that the KCNH1 mutations lead to altered channel activity.
| | | | A germline homozygous mutation in the base-excision repair gene NTHL1 causes adenomatous polyposis and colorectal cancer pp668 - 671
Robbert D A Weren, Marjolijn J L Ligtenberg, C Marleen Kets, Richarda M de Voer, Eugène T P Verwiel, Liesbeth Spruijt, Wendy A G van Zelst-Stams, Marjolijn C Jongmans, Christian Gilissen, Jayne Y Hehir-Kwa, Alexander Hoischen, Jay Shendure, Evan A Boyle, Eveline J Kamping, Iris D Nagtegaal, Bastiaan B J Tops, Fokko M Nagengast, Ad Geurts van Kessel, J Han J M van Krieken, Roland P Kuiper & Nicoline Hoogerbrugge
doi:10.1038/ng.3287
Roland Kuiper and colleagues identify a homozygous germline nonsense mutation in the base-excision repair gene NTHL1 in three families with recessive inheritance of adenomatous polyposis.
| | | | The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia pp672 - 676
Kajsa Paulsson, Henrik Lilljebjörn, Andrea Biloglav, Linda Olsson, Marianne Rissler, Anders Castor, Gisela Barbany, Linda Fogelstrand, Ann Nordgren, Helene Sjögren, Thoas Fioretos & Bertil Johansson
doi:10.1038/ng.3301
Kajsa Paulsson and colleagues performed whole-genome and/or whole-exome sequencing of 51 cases of high hyperdiploid pediatric acute lymphoblastic leukemia, which is characterized by a massive nonrandom gain of chromosomes. They found that high hyperdiploidy arose early during leukemogenesis and was the main leukemogenic event.
| | | | DNA replication fidelity in Mycobacterium tuberculosis is mediated by an ancestral prokaryotic proofreader pp677 - 681
Jeremy M Rock, Ulla F Lang, Michael R Chase, Christopher B Ford, Elias R Gerrick, Richa Gawande, Mireia Coscolla, Sebastien Gagneux, Sarah M Fortune & Meindert H Lamers
doi:10.1038/ng.3269
Sarah Fortune, Meindert Lamers and colleagues show that, unlike Escherichia coli, Mycobacterium tuberculosis uses an exonuclease domain in polymerase DnaE1 to proofread DNA replication. Importantly, this proofreading mechanism renders mycobacteria sensitive to nucleoside analogs, a class of small molecules used to treat viral infections and cancer.
| | Technical Report | Top | | | | Improved genome inference in the MHC using a population reference graph pp682 - 688
Alexander Dilthey, Charles Cox, Zamin Iqbal, Matthew R Nelson & Gil McVean
doi:10.1038/ng.3257
Gil McVean, Alexander Dilthey and colleagues present a graphical model-based method for accurate genomic assembly that uses the diversity present in multiple reference sequences, as represented by a population reference graph. The method is applied to simulated and empirical data from the human MHC region to demonstrate the improved accuracy of genomic inference.
| | Erratum | Top | | | | Erratum: The genome and transcriptome of the zoonotic hookworm Ancylostoma ceylanicum identify infection-specific gene families p689
Erich M Schwarz, Yan Hu, Igor Antoshechkin, Melanie M Miller, Paul W Sternberg & Raffi V Aroian
doi:10.1038/ng0615-689a
| | Corrigenda | Top | | | | Corrigendum: Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue p689
Colin S Cooper, Rosalind Eeles, David C Wedge, Peter Van Loo, Gunes Gundem, Ludmil B Alexandrov, Barbara Kremeyer, Adam Butler, Andrew G Lynch, Niedzica Camacho, Charlie E Massie, Jonathan Kay, Hayley J Luxton, Sandra Edwards, Zsofia Kote-Jarai, Nening Dennis, Sue Merson, Daniel Leongamornlert, Jorge Zamora, Cathy Corbishley, Sarah Thomas, Serena Nik-Zainal, Manasa Ramakrishna, Sarah O'Meara, Lucy Matthews, Jeremy Clark, Rachel Hurst, Richard Mithen, Robert G Bristow, Paul C Boutros, Michael Fraser, Susanna Cooke, Keiran Raine, David Jones, Andrew Menzies, Lucy Stebbings, Jon Hinton, Jon Teague, Stuart McLaren, Laura Mudie, Claire Hardy, Elizabeth Anderson, Olivia Joseph, Victoria Goody, Ben Robinson, Mark Maddison, Stephen Gamble, Christopher Greenman, Dan Berney, Steven Hazell, Naomi Livni, the ICGC Prostate Group, Cyril Fisher, Christopher Ogden, Pardeep Kumar, Alan Thompson, Christopher Woodhouse, David Nicol, Erik Mayer, Tim Dudderidge, Nimish C Shah, Vincent Gnanapragasam, Thierry Voet, Peter Campbell, Andrew Futreal, Douglas Easton, Anne Y Warren, Christopher S Foster, Michael R Stratton, Hayley C Whitaker, Ultan McDermott, Daniel S Brewer & David E Neal
doi:10.1038/ng0615-689b
| |  | | Corrigendum: A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome p689
Tin Aung, Mineo Ozaki, Takanori Mizoguchi, R Rand Allingham, Zheng Li, Aravind Haripriya, Satoko Nakano, Steffen Uebe, Jeffrey M Harder, Anita S Y Chan, Mei Chin Lee, Kathryn P Burdon, Yury S Astakhov, Khaled K Abu-Amero, Juan C Zenteno, Yildirim Nilgün, Tomasz Zarnowski, Mohammad Pakravan, Leen Abu Safieh, Liyun Jia, Ya Xing Wang, Susan Williams, Daniela Paoli, Patricio G Schlottmann, Lulin Huang, Kar Seng Sim, Jia Nee Foo, Masakazu Nakano, Yoko Ikeda, Rajesh S Kumar, Morio Ueno, Shin-ichi Manabe, Ken Hayashi, Shigeyasu Kazama, Ryuichi Ideta, Yosai Mori, Kazunori Miyata, Kazuhisa Sugiyama, Tomomi Higashide, Etsuo Chihara, Kenji Inoue, Satoshi Ishiko, Akitoshi Yoshida, Masahide Yanagi, Yoshiaki Kiuchi, Makoto Aihara, Tsutomu Ohashi, Toshiya Sakurai, Takako Sugimoto, Hideki Chuman, Fumihiko Matsuda, Kenji Yamashiro, Norimoto Gotoh, Masahiro Miyake, Sergei Y Astakhov, Essam A Osman, Saleh A Al-Obeidan, Ohoud Owaidhah, Leyla Al-Jasim, Sami Al Shahwan, Rhys A Fogarty, Paul Leo, Yaz Yetkin, Çilingir Oğuz, Mozhgan Rezaei Kanavi, Afsaneh Naderi Beni, Shahin Yazdani, Evgeny L Akopov, Kai-Yee Toh, Gareth R Howell, Andrew C Orr, Yufen Goh, Wee Yang Meah, Su Qin Peh, Ewa Kosior-Jarecka, Urszula Lukasik, Mandy Krumbiegel, Eranga N Vithana, Tien Yin Wong, Yutao Liu, Allison E Ashley Koch, Pratap Challa, Robyn M Rautenbach, David A Mackey, Alex W Hewitt, Paul Mitchell, Jie Jin Wang, Ari Ziskind, Trevor Carmichael, Rangappa Ramakrishnan, Kalpana Narendran, Rangaraj Venkatesh, Saravanan Vijayan, Peiquan Zhao, Xueyi Chen, Dalia Guadarrama-Vallejo, Ching Yu Cheng, Shamira A Perera, Rahat Husain, Su-Ling Ho, Ulrich-Christoph Welge-Luessen, Christian Mardin, Ursula Schloetzer-Schrehardt, Axel M Hillmer, Stefan Herms, Susanne Moebus, Markus M Nöthen, Nicole Weisschuh, Rohit Shetty, Arkasubhra Ghosh, Yik Ying Teo, Matthew A Brown, Ignacio Lischinsky, Blue Mountains Eye Study GWAS Team, Wellcome Trust Case Control Consortium 2, Jonathan G Crowston, Michae Coote, Bowen Zhao, Jinghong Sang, Nihong Zhang, Qisheng You, Vera Vysochinskaya, Panayiota Founti, Anthoula Chatzikyriakidou, Alexandros Lambropoulos, Eleftherios Anastasopoulos, Anne L Coleman, M Roy Wilson, Douglas J Rhee, Jae Hee Kang, Inna May-Bolchakova, Steffen Heegaard, Kazuhiko Mori, Wallace L M Alward, Jost B Jonas, Liang Xu, Jeffrey M Liebmann, Balram Chowbay, Elke Schaeffeler, Matthias Schwab, Fabian Lerner, Ningli Wang, Zhenglin Yang, Paolo Frezzotti, Shigeru Kinoshita, John H Fingert, Masaru Inatani, Kei Tashiro, André Reis, Deepak P Edward, Louis R Pasquale, Toshiaki Kubota, Janey L Wiggs, Francesca Pasutto, Fotis Topouzis, Michael Dubina, Jamie E Craig, Nagahisa Yoshimura, Periasamy Sundaresan, Simon W M John, Robert Ritch, Michael A Hauser & Chiea-Chuen Khor
doi:10.1038/ng0615-689c
| | | | Corrigendum: Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance p690
James J Crowley, Vasyl Zhabotynsky, Wei Sun, Shunping Huang, Isa Kemal Pakatci, Yunjung Kim, Jeremy R Wang, Andrew P Morgan, John D Calaway, David L Aylor, Zaining Yun, Timothy A Bell, Ryan J Buus, Mark E Calaway, John P Didion, Terry J Gooch, Stephanie D Hansen, Nashiya N Robinson, Ginger D Shaw, Jason S Spence, Corey R Quackenbush, Cordelia J Barrick, Randal J Nonneman, Kyungsu Kim, James Xenakis, Yuying Xie, William Valdar, Alan B Lenarcic, Wei Wang, Catherine E Welsh, Chen-Ping Fu, Zhaojun Zhang, James Holt, Zhishan Guo, David W Threadgill, Lisa M Tarantino, Darla R Miller, Fei Zou, Leonard McMillan, Patrick F Sullivan & Fernando Pardo-Manuel de Villena
doi:10.1038/ng0615-690a
| | | Top | | | Advertisement | | Nature Genetics in association with the Wellcome Trust present:
The Genomics of Common Diseases 2015
September 2-5, 2015 | Cambridge, UK
Register now! |  | | | | | | | | | | | | Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here.
Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. For event advertising opportunities across the Nature Publishing Group portfolio please contact natureevents@nature.com | | | | | |
| |
|
|
No comments:
Post a Comment