Molecular Therapy - Table of Contents alert Volume 23 Issue 4

If you are unable to see the message below, click here to view.

TABLE OF CONTENTS Volume 23, Issue 4 (April 2015) In this issue Editorial In This Issue Research Highlights Letter to the Editor Commentaries Original Articles Corrigendum Also new AOP Sign up for e-alerts Recommend to your library Web feed Subscribe Advertisement Celebrating the 25th Anniversary of SELEX: An Aptamer Symposium Supported by the American Society of Gene & Cell Therapy, the Aptamers Workshop will provide a unique opportunity to celebrate the 25th anniversary of aptamers and to meet researchers around the world developing nucleic acid aptamers as high affinity targeting reagents for both diagnosis and therapy. Find out more: www.asgct.org/am15/   Editorial Top From the Impact Factor to DORA and the Scientific Content of Articles Seppo Ylä-Herttuala Mol Ther 2015 23: 609; 10.1038/mt.2015.32 Full Text In This Issue Top In This Issue Mol Ther 2015 23: 610; 10.1038/mt.2015.33 Full Text Research Highlights Top Research Highlights Mol Ther 2015 23: 611; 10.1038/mt.2015.34 Full Text Letter to the Editor Top Transduction of antigen-presenting cells in the brain by AAV9 warrants caution in preclinical studies John Forsayeth and Krystof S Bankiewicz Mol Ther 2015 23: 612; 10.1038/mt.2015.35 Full Text In vivo secretion of anti-CD3 × anti-tumor bispecific antibodies by gene-modified cells: over a decade of T-cell engagement Marta Compte, Laura Sanz and Luis Álvarez-Vallina Mol Ther 2015 23: 612-613; 10.1038/mt.2015.36 Full Text Response to “In vivo secretion of anti-CD3 × anti-tumor bispecific antibodies by gene-modified cells: over a decade of T-cell engagement” Kota Iwahori, Xiao-Tong Song and Stephen Gottschalk Mol Ther 2015 23: 613; 10.1038/mt.2015.37 Full Text Commentaries Top A Shot in the Bone Corrects a Genetic Disease Brian D Brown Mol Ther 2015 23: 614-615; 10.1038/mt.2015.38 Full Text Antiobesity Strategy Targets Energy Economy Safeguards Michel Vivaudou and André Terzic Mol Ther 2015 23: 615-616; 10.1038/mt.2015.39 Full Text Original Articles Top Intraosseous Delivery of Lentiviral Vectors Targeting Factor VIII Expression in Platelets Corrects Murine Hemophilia A Xuefeng Wang, Simon C Shin, Andy F J Chiang, Iram Khan, Dao Pan, David J Rawlings and Carol H Miao Mol Ther 2015 23: 617-626; advance online publication, February 6, 2015; 10.1038/mt.2015.20 Abstract | Full Text Intra-Amniotic rAAV-Mediated Microdystrophin Gene Transfer Improves Canine X-Linked Muscular Dystrophy and May Induce Immune Tolerance Hiromi Hayashita-Kinoh, Naoko Yugeta, Hironori Okada, Yuko Nitahara-Kasahara, Tomoko Chiyo, Takashi Okada and Shin'ichi Takeda Mol Ther 2015 23: 627-637; advance online publication, January 14, 2015; 10.1038/mt.2015.5 Abstract | Full Text Broad Functional Correction of Molecular Impairments by Systemic Delivery of scAAVrh74-hSGSH Gene Delivery in MPS IIIA Mice F Jason Duncan, Bartholomew J Naughton, Kimberly Zaraspe, Darren A Murrey, Aaron S Meadows, Kelly Reed Clark, David E Newsom, Peter White, Haiyan Fu and Douglas M McCarty Mol Ther 2015 23: 638-647; advance online publication, January 16, 2015; 10.1038/mt.2015.9 Abstract | Full Text Characterization of a Bispecific FLT3 X CD3 Antibody in an Improved, Recombinant Format for the Treatment of Leukemia Michael Durben, Dominik Schmiedel, Martin Hofmann, Fabian Vogt, Tina Nübling, Elwira Pyz, Hans-Jörg Bühring, Hans-Georg Rammensee, Helmut R Salih, Ludger Große-Hovest and Gundram Jung Mol Ther 2015 23: 648-655; advance online publication, January 12, 2015; 10.1038/mt.2015.2 Abstract | Full Text HDAC Inhibitors Target HDAC5, Upregulate MicroRNA-125a-5p, and Induce Apoptosis in Breast Cancer Cells Tsung-Hua Hsieh, Chia-Yi Hsu, Cheng-Fang Tsai, Cheng-Yu Long, Chin-Hu Wu, Deng-Chyang Wu, Jau-Nan Lee, Wei-Chun Chang and Eing-Mei Tsai Mol Ther 2015 23: 656-666; advance online publication, December 22, 2014; 10.1038/mt.2014.247 Abstract | Full Text Hybrid Nonviral/Viral Vector Systems for Improved piggyBac DNA Transposon In Vivo Delivery Ashley L Cooney, Brajesh K Singh and Patrick L Sinn Mol Ther 2015 23: 667-674; advance online publication, January 5, 2015; 10.1038/mt.2014.254 Abstract | Full Text High Capsid–Genome Correlation Facilitates Creation of AAV Libraries for Directed Evolution Mathieu Nonnenmacher, Harm van Bakel, Roger J Hajjar and Thomas Weber Mol Ther 2015 23: 675-682; advance online publication, January 14, 2015; 10.1038/mt.2015.3 Abstract | Full Text Cell Cycle Status of CD34+ Hemopoietic Stem Cells Determines Lentiviral Integration in Actively Transcribed and Development-related Genes Eleni Papanikolaou, Anna Paruzynski, Ioannis Kasampalidis, Annette Deichmann, Evangelos Stamateris, Manfred Schmidt, Christof von Kalle and Nicholas P Anagnou Mol Ther 2015 23: 683-696; advance online publication, December 19, 2014; 10.1038/mt.2014.246 Abstract | Full Text Intrinsic Transgene Immunogenicity Gears CD8+ T-cell Priming After rAAV-Mediated Muscle Gene Transfer Maxime Carpentier, Stéphanie Lorain, Pascal Chappert, Mélanie Lalfer, Romain Hardet, Dominique Urbain, Cécile Peccate, Sahil Adriouch, Luis Garcia, Jean Davoust and David-Alexandre Gross Mol Ther 2015 23: 697-706; advance online publication, December 10, 2014; 10.1038/mt.2014.235 Abstract | Full Text Disruption of KATP Channel Expression in Skeletal Muscle by Targeted Oligonucleotide Delivery Promotes Activity-linked Thermogenesis Siva Rama Krishna Koganti, Zhiyong Zhu, Ekaterina Subbotina, Zhan Gao, Ana Sierra, Manuel Proenza, Liping Yang, Alexey Alekseev, Denice Hodgson-Zingman and Leonid Zingman Mol Ther 2015 23: 707-716; advance online publication, February 4, 2015; 10.1038/mt.2015.21 Abstract | Full Text The Clinical Relevance of the miR-197/CKS1B/STAT3-mediated PD-L1 Network in Chemoresistant Non-small-cell Lung CancerMTOPEN Yu Fujita, Shigehiro Yagishita, Keitaro Hagiwara, Yusuke Yoshioka, Nobuyoshi Kosaka, Fumitaka Takeshita, Tomohiro Fujiwara, Koji Tsuta, Hiroshi Nokihara, Tomohide Tamura, Hisao Asamura, Makoto Kawaishi, Kazuyoshi Kuwano and Takahiro Ochiya Mol Ther 2015 23: 717-727; advance online publication, January 19, 2015; 10.1038/mt.2015.10 Abstract | Full Text PET Imaging of Oncolytic VSV Expressing the Mutant HSV-1 Thymidine Kinase Transgene in a Preclinical HCC Rat Model Kim A Muñoz-Álvarez, Jennifer Altomonte, Iina Laitinen, Sibylle Ziegler, Katja Steiger, Irene Esposito, Roland M Schmid and Oliver Ebert Mol Ther 2015 23: 728-736; advance online publication, January 22, 2015; 10.1038/mt.2015.12 Abstract | Full Text Perforin Gene Transfer Into Hematopoietic Stem Cells Improves Immune Dysregulation in Murine Models of Perforin DeficiencyMTOPEN Marlene Carmo, Kimberly A Risma, Paritha Arumugam, Swati Tiwari, Adrianne E Hontz, Claudia A Montiel-Equihua, Maria E Alonso-Ferrero, Michael P Blundell, Axel Schambach, Christopher Baum, Punam Malik, Adrian J Thrasher, Michael B Jordan and H Bobby Gaspar Mol Ther 2015 23: 737-745; advance online publication, December 19, 2014; 10.1038/mt.2014.242 Abstract | Full Text Paracrine Factors of Human Fetal MSCs Inhibit Liver Cancer Growth Through Reduced Activation of IGF-1R/PI3K/Akt Signaling Yulyana Yulyana, Ivy A W Ho, Kian Chuan Sia, Jennifer P Newman, Xin Yi Toh, Berwini B Endaya, Jerry K Y Chan, Massimiliano Gnecchi, Hung Huynh, Alexander Y F Chung, Kiat Hon Lim, Hui Sun Leong, Narayanan Gopalakrishna Iyer, Kam Man Hui and Paula Y P Lam Mol Ther 2015 23: 746-756; advance online publication, January 26, 2015; 10.1038/mt.2015.13 Abstract | Full Text Chimeric Antigen Receptors With Mutated IgG4 Fc Spacer Avoid Fc Receptor Binding and Improve T Cell Persistence and Antitumor Efficacy Mahesh Jonnalagadda, Armen Mardiros, Ryan Urak, Xiuli Wang, Lauren J Hoffman, Alyssa Bernanke, Wen-Chung Chang, William Bretzlaff, Renate Starr, Saul Priceman, Julie R Ostberg, Stephen J Forman and Christine E Brown Mol Ther 2015 23: 757-768; advance online publication, November 4, 2014; 10.1038/mt.2014.208 Abstract | Full Text Enhancing Antitumor Efficacy of Chimeric Antigen Receptor T Cells Through Constitutive CD40L Expression Kevin J Curran, Beatrijs A Seinstra, Yan Nikhamin, Raymond Yeh, Yelena Usachenko, Dayenne G van Leeuwen, Terence Purdon, Hollie J Pegram and Renier J Brentjens Mol Ther 2015 23: 769-778; advance online publication, January 13, 2015; 10.1038/mt.2015.4 Abstract | Full Text First-in-man Phase 1 Clinical Trial of Gene Therapy for Advanced Pancreatic Cancer: Safety, Biodistribution, and Preliminary Clinical Findings Louis Buscail, Barbara Bournet, Fabienne Vernejoul, Gilles Cambois, Hubert Lulka, Naïma Hanoun, Marlène Dufresne, Aline Meulle, Alix Vignolle-Vidoni, Laetitia Ligat, Nathalie Saint-Laurent, Frédéric Pont, Sébastien Dejean, Marion Gayral, Frédéric Martins, Jérôme Torrisani, Odile Barbey, Fabian Gross, Rosine Guimbaud, Philippe Otal, Frédéric Lopez, Gérard Tiraby and Pierre Cordelier Mol Ther 2015 23: 779-789; advance online publication, January 14, 2015; 10.1038/mt.2015.1 Abstract | Full Text Corrigendum Top Corrigendum to “CD133-targeted Gene Transfer Into Long-term Repopulating Hematopoietic Stem Cells” Mol Ther 2015 23: 790; 10.1038/mt.2015.26 Full Text Corrigendum to “Let-7 microRNAs Regenerate Peripheral Nerve Regeneration by Targeting Nerve Growth Factor” Mol Ther 2015 23: 790; 10.1038/mt.2014.255 Full Text Please note that you need to be a subscriber or site-license holder to enjoy full-text access to Molecular Therapy. In order to do so, please purchase a subscription. You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/nams/svc/myaccount (You will need to log in to be recognised as a nature.com registrant). For further technical assistance, please contact our registration department. For print subscription enquiries, please contact our subscription department. For other enquiries, please contact our customer feedback department. Nature Publishing Group | 75 Varick Street, 9th Floor | New York | NY 10013-1917 | USA Nature Publishing Group's worldwide offices: London - Paris - Munich - New Delhi - Tokyo - Melbourne San Diego - San Francisco - Washington - New York - Boston Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at Brunel Road, Houndmills, Basingstoke, Hampshire RG21 6XS. © 2015 Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.