TABLE OF CONTENTS
|  |  |  | Volume 135, Issue 5 (May 2015) |  | In this issue Editorial Research Techniques Made Simple JID VisualDx Quiz Cells to Surgery Quiz Commentaries Reviews Original Articles Letters to the Editor
Also new    AOP | |  |  |  | | Advertisement |  | The International Societies of Investigative Dermatology Announce an Informational Open Discussion on Goals, Approach and Membership Opportunities
Designated representatives of cutaneous biology research societies worldwide are invited to attend. The meeting will be held on Saturday, May 9, 2015 at 2:00 pm in the Hilton Atlanta Hotel. Details can be found here. | | | |  |  | Editorial | Top |  | Biologics for Psoriasis: A Translational Research Success StoryMark Lebwohl J Invest Dermatol 2015 135: 1205-1207; 10.1038/jid.2014.549 Full Text | PDF |  |  |  | Clinical SnippetsJ Invest Dermatol 2015 135: 1208; 10.1038/jid.2015.96 Full Text | PDF |  |  |  | BJD Editor's ChoiceJ Invest Dermatol 2015 135: 1209; 10.1038/jid.2015.97 Full Text | PDF |  |  |  | Editors' PicksJ Invest Dermatol 2015 135: 1210; 10.1038/jid.2015.98 Full Text | PDF |  | Research Techniques Made Simple
| Top |  | How MicroRNAs Modify Protein ProductionJessica L Feig, Keith M Giles, Iman Osman and Andrew G Franks Jr. J Invest Dermatol 2015 135: e32; 10.1038/jid.2015.99 Full Text | PDF |  | JID VisualDx Quiz
| Top |  | JID VisualDx Quiz: May 2015Alejandra C Vivas and Robert S Kirsner J Invest Dermatol 2015 135: e28; 10.1038/jid.2015.100 Full Text | PDF |  | Cells to Surgery Quiz
| Top |  | Cells to Surgery Quiz: May 2015Fleta N Bray, Mohammed Alsaidan, Leyre Falto-Aizpurua, Brian J Simmons, Mohammad-Ali Yazdani Abyaneh, Robert D Griffith and Keyvan Nouri J Invest Dermatol 2015 135: e13; 10.1038/jid.2015.101 Full Text | PDF |  | Commentaries | Top |  | Association between Betapapillomavirus Seropositivity and Keratinocyte Carcinoma—Prospects for Prophylactic Vaccination?Herbert Pfister J Invest Dermatol 2015 135: 1211-1213; 10.1038/jid.2014.523 Abstract | Full Text | PDF |  |  |  | Itch, Eosinophils, and Autoimmunity: A Novel Murine Model of Bullous PemphigoidKim B Yancey J Invest Dermatol 2015 135: 1213-1215; 10.1038/jid.2014.537 Abstract | Full Text | PDF |  |  |  | Autophagy as a Melanocytic Self-Defense MechanismVijayasaradhi Setaluri J Invest Dermatol 2015 135: 1215-1217; 10.1038/jid.2015.19 Abstract | Full Text | PDF |  |  |  | Multifaceted Contributions of Epidermal Langerhans Cells to Cutaneous CarcinogenesisBjörn E Clausen and Stephan Grabbe J Invest Dermatol 2015 135: 1218-1220; 10.1038/jid.2014.520 Abstract | Full Text | PDF |  |  |  | How does the Merkel Polyomavirus Lead to a Lethal Cancer? Many Answers, Many Questions, and a New Mouse ModelCandice D Church and Paul Nghiem J Invest Dermatol 2015 135: 1221-1224; 10.1038/jid.2015.4 Abstract | Full Text | PDF |  | Reviews | Top |  | The Role of Human Dendritic Cells in HIV-1 InfectionZahra Ahmed, Tatsuyoshi Kawamura, Shinji Shimada and Vincent Piguet J Invest Dermatol 2015 135: 1225-1233; advance online publication, November 19, 2014; 10.1038/jid.2014.490 Abstract | Full Text | PDF |  |  |  | Placebo Effects on Itch: A Meta-Analysis of Clinical Trials of Patients with Dermatological ConditionsAntoinette I M van Laarhoven, Ineke M van der Sman-Mauriks, A Rogier T Donders, Mathilde C Pronk, Peter C M van de Kerkhof and Andrea W M Evers J Invest Dermatol 2015 135: 1234-1243; advance online publication, December 1, 2014; 10.1038/jid.2014.522 Abstract | Full Text | PDF |  | Original Articles | Top |  | APPENDAGES | Oxidative Stress–Associated Senescence in Dermal Papilla Cells of Men with Androgenetic AlopeciaJames H Upton, Rosalind F Hannen, Adiam W Bahta, Nilofer Farjo, Bessam Farjo and Michael P Philpott J Invest Dermatol 2015 135: 1244-1252; advance online publication, February 3, 2015; 10.1038/jid.2015.28 Abstract | Full Text | PDF |  |  |  | An Autosomal Recessive Mutation of DSG4 Causes Monilethrix through the ER Stress ResponseMadoka Kato, Akira Shimizu, Yoko Yokoyama, Kyoichi Kaira, Yutaka Shimomura, Akemi Ishida-Yamamoto, Kiyoko Kamei, Fuminori Tokunaga and Osamu Ishikawa J Invest Dermatol 2015 135: 1253-1260; advance online publication, January 23, 2015; 10.1038/jid.2015.12 Abstract | Full Text | PDF |  |  |  | CLINICAL RESEARCH | Monochloroacetic Acid Application Is an Effective Alternative to Cryotherapy for Common and Plantar Warts in Primary Care: A Randomized Controlled TrialSjoerd C Bruggink, Jacobijn Gussekloo, Paulette F Egberts, Jan Nico Bouwes Bavinck, Margot W M de Waal, Willem J J Assendelft and Just A H Eekhof J Invest Dermatol 2015 135: 1261-1267; advance online publication, February 5, 2015; 10.1038/jid.2015.1 Abstract | Full Text | PDF |  |  |  | CONNECTIVE TISSUE | MMP-1 and -3 Promoter Variants Are Indicative of a Common Susceptibility for Skin and Lung Aging: Results from a Cohort of Elderly Women (SALIA)Andrea Vierkötter, Tamara Schikowski, Dorothea Sugiri, Mary S Matsui, Ursula Krämer and Jean Krutmann J Invest Dermatol 2015 135: 1268-1274; advance online publication, January 19, 2015; 10.1038/jid.2015.7 Abstract | Full Text | PDF |  |  |  | EPIDEMIOLOGY | The Presence of Betapapillomavirus Antibodies around Transplantation Predicts the Development of Keratinocyte Carcinoma in Organ Transplant Recipients: A Cohort StudyRoel E Genders, Hadi Mazlom, Angelika Michel, Elsemieke I Plasmeijer, Koen D Quint, Michael Pawlita, Els van der Meijden, Tim Waterboer, Hans de Fijter, Frans H Claas, Ron Wolterbeek, Mariet C W Feltkamp and Jan Nico Bouwes Bavinck J Invest Dermatol 2015 135: 1275-1282; advance online publication, October 27, 2014; 10.1038/jid.2014.456 Abstract | Full Text | PDF |  |  |  | Psoriasis and Cardiometabolic Traits: Modest Association but Distinct Genetic ArchitecturesManja Koch, Hansjörg Baurecht, Janina S Ried, Elke Rodriguez, Sabrina Schlesinger, Natalie Volks, Christian Gieger, Ina-Maria Rückert, Luise Heinrich, Christina Willenborg, Catherine Smith, Annette Peters, Barbara Thorand, Wolfgang Koenig, Claudia Lamina, Henning Jansen, Florian Kronenberg, Jochen Seissler, Joachim Thiery, Wolfgang Rathmann, Heribert Schunkert, Jeanette Erdmann, Jonathan Barker, Rajan P Nair, Lam C Tsoi, James T Elder, Ulrich Mrowietz, Michael Weichenthal, Sören Mucha, Stefan Schreiber, Andre Franke, Jochen Schmitt, Wolfgang Lieb and Stephan Weidinger J Invest Dermatol 2015 135: 1283-1293; advance online publication, January 19, 2015; 10.1038/jid.2015.8 Abstract | Full Text | PDF |  |  |  | GENETICS | Genetic Heterogeneity of Pseudoxanthoma Elasticum: The Chinese Signature Profile of ABCC6 and ENPP1 MutationsLiang Jin, Qiujie Jiang, Zhengsheng Wu, Changxia Shao, Yong Zhou, Luting Yang, Jouni Uitto and Gang Wang J Invest Dermatol 2015 135: 1294-1302; advance online publication, January 23, 2015; 10.1038/jid.2015.10 Abstract | Full Text | PDF |  |  |  | IMMUNOLOGY/INFECTION | Deletion of the Major Bullous Pemphigoid Epitope Region of Collagen XVII Induces Blistering, Autoimmunization, and Itching in MiceTiina Hurskainen, Nina Kokkonen, Raija Sormunen, Joanna Jackow, Stefanie Löffek, Raija Soininen, Claus-Werner Franzke, Leena Bruckner-Tuderman and Kaisa Tasanen J Invest Dermatol 2015 135: 1303-1310; advance online publication, October 13, 2014; 10.1038/jid.2014.443 Abstract | Full Text | PDF |  |  |  | NKG2D-Dependent Activation of Dendritic Epidermal T Cells in Contact HypersensitivityMorten M Nielsen, Beatrice Dyring-Andersen, Jonas D Schmidt, Deborah Witherden, Paola Lovato, Anders Woetmann, Niels Ødum, Steen S Poulsen, Wendy L Havran, Carsten Geisler and Charlotte M Bonefeld J Invest Dermatol 2015 135: 1311-1319; advance online publication, January 29, 2015; 10.1038/jid.2015.23 Abstract | Full Text | PDF |  |  |  | KERATINOCYTES/EPIDERMIS | Genetic and Pharmacological Analysis Identifies a Physiological Role for the AHR in Epidermal DifferentiationEllen H van den Bogaard, Michael A Podolsky, Jos P Smits, Xiao Cui, Christian John, Krishne Gowda, Dhimant Desai, Shantu G Amin, Joost Schalkwijk, Gary H Perdew and Adam B Glick J Invest Dermatol 2015 135: 1320-1328; advance online publication, January 20, 2015; 10.1038/jid.2015.6 Abstract | Full Text | PDF |  |  |  | An Alternatively Spliced IL-15 Isoform Modulates Abrasion-Induced Keratinocyte ActivationTsung-Lin Lee, Mei-Ling Chang, Yu-Jei Lin, Ming-Hsun Tsai, Yi-Hsuan Chang, Che-Ming Chuang, Yun Chien, Tomasz Sosinowski, Chih-Hsiu Wang, Yi-Yuan Chen, Chien-Kuo Lee, Jau-Shiuh Chen, Li-Fang Wang, John T Kung and Chia-Chi Ku J Invest Dermatol 2015 135: 1329-1337; advance online publication, January 23, 2015; 10.1038/jid.2015.17 Abstract | Full Text | PDF |  |  |  | Keratitis-Ichthyosis-Deafness Syndrome-Associated Cx26 Mutants Produce Nonfunctional Gap Junctions but Hyperactive Hemichannels When Co-Expressed With Wild Type Cx43Isaac E García, Jaime Maripillán, Oscar Jara, Ricardo Ceriani, Angelina Palacios-Muñoz, Jayalakshmi Ramachandran, Pablo Olivero, Tomas Perez-Acle, Carlos González, Juan C Sáez, Jorge E Contreras and Agustín D Martínez J Invest Dermatol 2015 135: 1338-1347; advance online publication, January 27, 2015; 10.1038/jid.2015.20 Abstract | Full Text | PDF |  |  |  | MELANOCYTES/MELANOMA | Suppression of Autophagy Dysregulates the Antioxidant Response and Causes Premature Senescence of MelanocytesCheng-Feng Zhang, Florian Gruber, Chunya Ni, Michael Mildner, Ulrich Koenig, Susanne Karner, Caterina Barresi, Heidemarie Rossiter, Marie-Sophie Narzt, Ionela M Nagelreiter, Lionel Larue, Desmond J Tobin, Leopold Eckhart and Erwin Tschachler J Invest Dermatol 2015 135: 1348-1357; advance online publication, October 7, 2014; 10.1038/jid.2014.439 Abstract | Full Text | PDF |  |  |  | eIF4E Is an Adverse Prognostic Marker of Melanoma Patient Survival by Increasing Melanoma Cell InvasionShahram Khosravi, Kevin J Tam, Gholamreza S Ardekani, Magdalena Martinka, Kevin J McElwee and Christopher J Ong J Invest Dermatol 2015 135: 1358-1367; advance online publication, January 6, 2015; 10.1038/jid.2014.552 Abstract | Full Text | PDF |  |  |  | The Role of eIF4E in Response and Acquired Resistance to Vemurafenib in MelanomaYao Zhan, Michael S Dahabieh, Arjuna Rajakumar, Monica C Dobocan, Marie-Noël M’Boutchou, Christophe Goncalves, Lucy Shiru L., Filippa Pettersson, Ivan Topisirovic, Léon van Kempen, Sonia V del Rincón and Wilson H Miller Jr. J Invest Dermatol 2015 135: 1368-1376; advance online publication, January 23, 2015; 10.1038/jid.2015.11 Abstract | Full Text | PDF |  |  |  | Independent Validation of Six Melanoma Risk Prediction ModelsCatherine M Olsen, Rachel E Neale, Adèle C Green, Penelope M Webb, the QSkin Study, the Epigene Study and David C Whiteman J Invest Dermatol 2015 135: 1377-1384; advance online publication, December 30, 2014; 10.1038/jid.2014.533 Abstract | Full Text | PDF |  |  |  | p21-Activated Kinase 4 Critically Regulates Melanogenesis via Activation of the CREB/MITF and β-Catenin/MITF PathwaysCheong-Yong Yun, Soon-Tae You, Jin-Hwa Kim, Jin H Chung, Sang-Bae Han, Eun-Young Shin and Eung-Gook Kim J Invest Dermatol 2015 135: 1385-1394; advance online publication, January 5, 2015; 10.1038/jid.2014.548 Abstract | Full Text | PDF |  |  |  | PHOTOBIOLOGY | Caspase-1 Activity Is Required for UVB-Induced Apoptosis of Human KeratinocytesGabriel Sollberger, Gerhard E Strittmatter, Serena Grossi, Martha Garstkiewicz, Ulrich auf dem Keller, Lars E French and Hans-Dietmar Beer J Invest Dermatol 2015 135: 1395-1404; advance online publication, January 6, 2015; 10.1038/jid.2014.551 Abstract | Full Text | PDF |  |  |  | TUMOR BIOLOGY | Mechanisms of Chemical Cooperative Carcinogenesis by Epidermal Langerhans CellsJulia M Lewis, Christina D Bürgler, Juliet A Fraser, Haihui Liao, Kseniya Golubets, Cynthia L Kucher, Peter Y Zhao, Renata B Filler, Robert E Tigelaar and Michael Girardi J Invest Dermatol 2015 135: 1405-1414; advance online publication, September 18, 2014; 10.1038/jid.2014.411 Abstract | Full Text | PDF |  |  |  | Merkel Cell Polyomavirus Small T Antigen Is Oncogenic in Transgenic MiceMonique E Verhaegen, Doris Mangelberger, Paul W Harms, Tracy D Vozheiko, Jack W Weick, Dawn M Wilbert, Thomas L Saunders, Alexandre N Ermilov, Christopher K Bichakjian, Timothy M Johnson, Michael J Imperiale and Andrzej A Dlugosz J Invest Dermatol 2015 135: 1415-1424; advance online publication, October 14, 2014; 10.1038/jid.2014.446 Abstract | Full Text | PDF |  |  |  | WOUND HEALING | Kruppel-Like Factor KLF4 Facilitates Cutaneous Wound Healing by Promoting Fibrocyte Generation from Myeloid-Derived Suppressor CellsLingling Ou, Ying Shi, Wenqi Dong, Chunming Liu, Thomas J Schmidt, Prakash Nagarkatti, Mitzi Nagarkatti, Daping Fan and Walden Ai J Invest Dermatol 2015 135: 1425-1434; advance online publication, January 12, 2015; 10.1038/jid.2015.3 Abstract | Full Text | PDF |  |  |  | Reduced Granulation Tissue and Wound Strength in the Absence of α11β1 IntegrinJIDOPENJan-Niklas Schulz, Cédric Zeltz, Ida W Sørensen, Malgorzata Barczyk, Sergio Carracedo, Ralf Hallinger, Anja Niehoff, Beate Eckes and Donald Gullberg J Invest Dermatol 2015 135: 1435-1444; advance online publication, January 29, 2015; 10.1038/jid.2015.24 Abstract | Full Text | PDF |  | Letters to the Editor | Top |  | Malignancies in Pemphigus and Pemphigoid DiseasesFranziska Schulze, Kathrin Neumann, Andreas Recke, Detlef Zillikens, Roland Linder and Enno Schmidt J Invest Dermatol 2015 135: 1445-1447; advance online publication, January 5, 2015; 10.1038/jid.2014.547 Full Text | PDF |  |  |  | The Kindler Syndrome: A Spectrum of FERMT1 Mutations in Iranian FamiliesLeila Youssefian, Hassan Vahidnezhad, Mohammadreza Barzegar, Qiaoli Li, Soheila Sotoudeh, Ameneh Yazdanfar, Amir Hooshang Ehsani, Abdol-Mohammad Kajbafzadeh, Nikoo Mozafari, Nasser Ebrahimi Daryani, Farzaneh Agha-hosseini, Sirous Zeinali and Jouni Uitto J Invest Dermatol 2015 135: 1447-1450; advance online publication, January 19, 2015; 10.1038/jid.2015.9 Full Text | PDF |  |  |  | Fibroadipose Hyperplasia versus Proteus Syndrome: Segmental Overgrowth with a Mosaic Mutation in the PIK3CA GeneLeila Youssefian, Hassan Vahidnezhad, Taghi Baghdadi, Alireza Ghaznavi, Qiaoli Li, Mina Tabrizi and Jouni Uitto J Invest Dermatol 2015 135: 1450-1453; advance online publication, January 23, 2015; 10.1038/jid.2015.15 Full Text | PDF |  |  |  | Suppression of Basophil FcεRI Activation by Serum from Active Chronic Idiopathic/Spontaneous Urticaria (CIU/CSU) SubjectsPatricia M Sterba, Robert G Hamilton and Sarbjit S Saini J Invest Dermatol 2015 135: 1454-1456; advance online publication, February 3, 2015; 10.1038/jid.2015.13 Full Text | PDF |  |  |  | Loss of Primary Cilia in Melanoma Cells Is Likely Independent of Proliferation and Cell Cycle ProgressionElizabeth R Snedecor, Clifford C Sung, Alejandra Moncayo, Brooke E Rothstein, Daniel C Mockler, Marcia G Tonnesen, Evan C Jones, Mayumi Fujita, Richard A Clark, Kenneth R Shroyer and Jiang Chen J Invest Dermatol 2015 135: 1456-1458; advance online publication, January 28, 2015; 10.1038/jid.2015.22 Full Text | PDF |  |  |  | Silver Sulfadiazine Retards Wound Healing in Mice via Alterations in Cytokine ExpressionJamie Rosen, Angelo Landriscina, Allison Kutner, Brandon L Adler, Aimee E Krausz, Joshua D Nosanchuk and Adam J Friedman J Invest Dermatol 2015 135: 1459-1462; advance online publication, January 27, 2015; 10.1038/jid.2015.21 Full Text | PDF |  |  |  | Please note that you need to be a subscriber or site-license holder to enjoy full-text access to The Journal of Investigative Dermatology. 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