TABLE OF CONTENTS  
  |    |   |   |  Volume 135, Issue 4 (April 2015)  |     | In this issue   Editorial   Research Techniques Made Simple   JID VisualDx Quiz   Cells to Surgery Quiz   In Memoriam   Commentaries   Meeting Report   Reviews   Original Articles   Letters to the Editor
   	Also new     		  		    AOP |  	 |     |    |   	                               |   | Advertisement |     |            The International Societies of Investigative Dermatology Announce an Informational Open Discussion on Goals, Approach and Membership Opportunities 
  Designated representatives of cutaneous biology research societies worldwide are invited to attend. The meeting will be held on Saturday, May 9, 2015 at 2:00 pm in the Hilton Atlanta Hotel. Details can be found here.   |    |    |    |     |     |                  Editorial |  Top |    |   An α-MSH Analog in Erythropoietic ProtoporphyriaThomas A Luger and  Markus Böhm J Invest Dermatol 2014 135: 929-931; 10.1038/jid.2015.16 Full Text | PDF  |    |    |    |   Clinical SnippetsJ Invest Dermatol 2014 135: 932; 10.1038/jid.2015.33 Full Text | PDF  |    |    |    |   BJD Editor's ChoiceJ Invest Dermatol 2014 135: 933; 10.1038/jid.2015.34 Full Text | PDF  |    |    |    |   Editors' PicksJ Invest Dermatol 2015 135: 934; 10.1038/jid.2015.35 Full Text | PDF  |    |      Research Techniques Made Simple
 |  Top |    |   The Use of Luminex Assays to Measure CytokinesSaami Khalifian,  Giorgio Raimondi and  Gerald Brandacher J Invest Dermatol 2014 135: e31; 10.1038/jid.2015.36 Full Text | PDF  |    |      JID VisualDx Quiz
 |  Top |    |   JID VisualDx Quiz: April 2015Andrew Ross and  Robert S Kirsner J Invest Dermatol 2015 135: e27; 10.1038/jid.2015.37 Full Text | PDF  |    |     Cells to Surgery Quiz
 |  Top |    |   Cells to Surgery Quiz: April 2015Brian J Simmons,  Fleta N Bray,  Leyre Falto-Aizpurua,  Mohammed Alsaidan,  Robert D Griffith and  Keyvan Nouri J Invest Dermatol 2015 135: e12; 10.1038/jid.2015.38 Full Text | PDF  |    |    In Memoriam |  Top |    |   Leonard C. Harber (1927–2014)David R Bickers J Invest Dermatol 2015 135: 935-936; 10.1038/jid.2014.550 Full Text | PDF  |    |    Commentaries |  Top |    |   Next-Generation Sequencing for Mutation Detection in Heritable Skin Diseases: The Paradigm of Pseudoxanthoma ElasticumAndrew P South,  Qiaoli Li and  Jouni Uitto J Invest Dermatol 2015 135: 937-940; 10.1038/jid.2014.521 Abstract | Full Text | PDF  |    |    |    |   The Double Life of Connexin Channels: Single Is a TreatRoberto Bruzzone J Invest Dermatol 2015 135: 940-943; 10.1038/jid.2014.524 Abstract | Full Text | PDF  |    |    |    |   When the Circadian Clock Meets the Melanin Pigmentary SystemAndrzej T Slominski,  Rüdiger Hardeland and  Russel J Reiter J Invest Dermatol 2015 135: 943-945; 10.1038/jid.2014.553 Abstract | Full Text | PDF  |    |    |    |   Hsp90 Inhibitor Can Inhibit UV CarcinogenesisSantosh K Katiyar J Invest Dermatol 2015 135: 945-947; 10.1038/jid.2014.504 Abstract | Full Text | PDF  |    |    |    |   Focus on Early Detection to Reduce Melanoma DeathsAlan C Geller,  Susan M Swetter and  Martin A Weinstock J Invest Dermatol 2015 135: 947-949; 10.1038/jid.2014.534 Abstract | Full Text | PDF  |    |    Meeting Report |  Top |    |   Montagna Symposium 2014—Skin Aging: Molecular Mechanisms and Tissue ConsequencesBarbara A Gilchrest,  Judith Campisi,  Howard Y Chang,  Gary J Fisher and  Molly F Kulesz-Martin J Invest Dermatol 2015 135: 950-953; 10.1038/jid.2014.546 Full Text | PDF  |    |    Reviews |  Top |    |   The Scientific Legacy of Stephen RothmanWalter H C Burgdorf and  David R Bickers J Invest Dermatol 2015 135: 954-959; advance online publication, November 6, 2014; 10.1038/jid.2014.447 Abstract | Full Text | PDF  |    |    |    |   miR-214 as a Key Hub that Controls Cancer Networks: Small Player, Multiple FunctionsElisa Penna,  Francesca Orso and  Daniela Taverna J Invest Dermatol 2015 135: 960-969; advance online publication, December 11, 2014; 10.1038/jid.2014.479 Abstract | Full Text | PDF  |    |    Original Articles |  Top |    |  CLINICAL RESEARCH |   Maintenance Therapy of Adult Vitiligo with 0.1% Tacrolimus Ointment: A Randomized, Double Blind, Placebo–Controlled StudyMarine Cavalié,  Khaled Ezzedine,  Eric Fontas,  Henri Montaudié,  Emeline Castela,  Philippe Bahadoran,  Alain Taïeb,  Jean-Philippe Lacour and  Thierry Passeron J Invest Dermatol 2015 135: 970-974; advance online publication, December 18, 2014; 10.1038/jid.2014.527 Abstract | Full Text | PDF  |    |    |    |  EPIDEMIOLOGY |   Aspirin and Nonsteroidal Anti-Inflammatory Drugs Can Prevent Cutaneous Squamous Cell Carcinoma: a Systematic Review and Meta-AnalysisChiho Muranushi,  Catherine M Olsen,  Nirmala Pandeya and  Adèle C Green J Invest Dermatol 2015 135: 975-983; advance online publication, December 18, 2014; 10.1038/jid.2014.531 Abstract | Full Text | PDF  |    |    |    |   The Psychological Burden of Skin Diseases: A Cross-Sectional Multicenter Study among Dermatological Out-Patients in 13 European CountriesJIDOPENFlorence J Dalgard,  Uwe Gieler,  Lucia Tomas-Aragones,  Lars Lien,  Francoise Poot,  Gregor B E Jemec,  Laurent Misery,  Csanad Szabo,  Dennis Linder,  Francesca Sampogna,  Andrea W M Evers,  Jon Anders Halvorsen,  Flora Balieva,  Jacek Szepietowski,  Dmitry Romanov,  Servando E Marron,  Ilknur K Altunay,  Andrew Y Finlay,  Sam S Salek and  Jörg Kupfer J Invest Dermatol 2015 135: 984-991; advance online publication, December 18, 2014; 10.1038/jid.2014.530 Abstract | Full Text | PDF  |    |    |    |  GENETICS |   Efficiency of Exome Sequencing for the Molecular Diagnosis of Pseudoxanthoma ElasticumJIDOPENMohammad J Hosen,  Filip Van Nieuwerburgh,  Wouter Steyaert,  Dieter Deforce,  Ludovic Martin,  Georges Leftheriotis,  Anne De Paepe,  Paul J Coucke and  Olivier M Vanakker J Invest Dermatol 2015 135: 992-998; advance online publication, September 29, 2014; 10.1038/jid.2014.421 Abstract | Full Text | PDF  |    |    |    |  IMMUNOLOGY/INFECTION |   Epidermal Elafin Expression Is an Indicator of Poor Prognosis in Cutaneous Graft-versus-Host DiseaseMarie-Charlotte Brüggen,  Peter Petzelbauer,  Hildegard Greinix,  Emmanuel Contassot,  Dragana Jankovic,  Lars French,  Gérard Socié,  Werner Rabitsch,  Zoya Kuzmina,  Peter Kalhs,  Robert Knobler,  Georg Stingl and  Georg Stary J Invest Dermatol 2015 135: 999-1006; advance online publication, November 18, 2014; 10.1038/jid.2014.489 Abstract | Full Text | PDF  |    |    |    |   Dermal Vγ4+ γδ T Cells Possess a Migratory Potency to the Draining Lymph Nodes and Modulate CD8+ T-Cell Activity through TNF-α ProductionSatoshi Nakamizo,  Gyohei Egawa,  Michio Tomura,  Shunsuke Sakai,  Soken Tsuchiya,  Akihiko Kitoh,  Tetsuya Honda,  Atsushi Otsuka,  Saeko Nakajima,  Teruki Dainichi,  Hideaki Tanizaki,  Masao Mitsuyama,  Yukihiko Sugimoto,  Kazuhiro Kawai,  Yasunobu Yoshikai,  Yoshiki Miyachi and  Kenji Kabashima J Invest Dermatol 2015 135: 1007-1015; advance online publication, December 10, 2014; 10.1038/jid.2014.516 Abstract | Full Text | PDF  |    |    |    |   RNA-Seq and ChIP-Seq Reveal SQSTM1/p62 as a Key Mediator of JunB Suppression of NF-κB-Dependent InflammationXiaoling Zhang,  Jane Y Jin,  Joseph Wu,  Xiaoxia Qin,  Robert Streilein,  Russell P Hall and  Jennifer Y Zhang J Invest Dermatol 2015 135: 1016-1024; advance online publication, December 16, 2014; 10.1038/jid.2014.519 Abstract | Full Text | PDF  |    |    |    |   IL-36γ (IL-1F9) Is a Biomarker for Psoriasis Skin LesionsAngelo Massimiliano D'Erme,  Dagmar Wilsmann-Theis,  Julia Wagenpfeil,  Michael Hölzel,  Sandra Ferring-Schmitt,  Sonja Sternberg,  Miriam Wittmann,  Bettina Peters,  Andreas Bosio,  Thomas Bieber and  Joerg Wenzel J Invest Dermatol 2015 135: 1025-1032; advance online publication, December 19, 2014; 10.1038/jid.2014.532 Abstract | Full Text | PDF  |    |    |    |  KERATINOCYTES/EPIDERMIS |   Aberrant Connexin26 Hemichannels Underlying Keratitis–Ichthyosis–Deafness Syndrome Are Potently Inhibited by MefloquineNoah A Levit,  Caterina Sellitto,  Hong-Zhan Wang,  Leping Li,  Miduturu Srinivas,  Peter R Brink and  Thomas W White J Invest Dermatol 2015 135: 1033-1042; advance online publication, September 17, 2014; 10.1038/jid.2014.408 Abstract | Full Text | PDF  |    |    |    |   Alpha Actinin-1 Regulates Cell-Matrix Adhesion Organization in Keratinocytes: Consequences for Skin Cell MotilityKevin J Hamill,  Sho Hiroyasu,  Zachary T Colburn,  Rosa V Ventrella,  Susan B Hopkinson,  Omar Skalli and  Jonathan C R Jones J Invest Dermatol 2015 135: 1043-1052; advance online publication, November 28, 2014; 10.1038/jid.2014.505 Abstract | Full Text | PDF  |    |    |    |  MELANOCYTES/MELANOMA |   The Peripheral Clock Regulates Human PigmentationJonathan A Hardman,  Desmond J Tobin,  Iain S Haslam,  Nilofer Farjo,  Bessam Farjo,  Yusur Al-Nuaimi,  Benedetto Grimaldi and  Ralf Paus J Invest Dermatol 2015 135: 1053-1064; advance online publication, October 13, 2014; 10.1038/jid.2014.442 Abstract | Full Text | PDF  |    |    |    |   IMP-3 Promotes Migration and Invasion of Melanoma Cells by Modulating the Expression of HMGA2 and Predicts Poor Prognosis in MelanomaYi-Shuan Sheen,  Yi-Hua Liao,  Ming-Hsien Lin,  Chia-Ying Chu,  Bing-Ying Ho,  Meng-Chen Hsieh,  Pin-Chun Chen,  Shih-Ting Cha,  Yung-Ming Jeng,  Cheng-Chi Chang,  Hsien-Ching Chiu,  Shiou-Hwa Jee,  Min-Liang Kuo and  Chia-Yu Chu J Invest Dermatol 2015 135: 1065-1073; advance online publication, November 7, 2014; 10.1038/jid.2014.480 Abstract | Full Text | PDF  |    |    |    |   Updated Field Synopsis and Systematic Meta-Analyses of Genetic Association Studies in Cutaneous Melanoma: The MelGene DatabaseKyriaki Antonopoulou,  Irene Stefanaki,  Christina M Lill,  Foteini Chatzinasiou,  Katerina P Kypreou,  Fani Karagianni,  Emmanouil Athanasiadis,  George M Spyrou,  John P A Ioannidis,  Lars Bertram,  Evangelos Evangelou and  Alexander J Stratigos J Invest Dermatol 2015 135: 1074-1079; advance online publication, November 19, 2014; 10.1038/jid.2014.491 Abstract | Full Text | PDF  |    |    |    |   Simvastatin Prevents and Reverses Depigmentation in a Mouse Model of VitiligoPriti Agarwal,  Mehdi Rashighi,  Kingsley I Essien,  Jillian M Richmond,  Louise Randall,  Hamidreza Pazoki-Toroudi,  Christopher A Hunter and  John E Harris J Invest Dermatol 2015 135: 1080-1088; advance online publication, December 18, 2014; 10.1038/jid.2014.529 Abstract | Full Text | PDF  |    |    |    |   BAP1 Has a Survival Role in Cutaneous MelanomaRaj Kumar,  Michael Taylor,  Benchun Miao,  Zhenyu Ji,  Jenny C-N Njauw,  Göran Jönsson,  Dennie T Frederick and  Hensin Tsao J Invest Dermatol 2015 135: 1089-1097; advance online publication, December 18, 2014; 10.1038/jid.2014.528 Abstract | Full Text | PDF  |    |    |    |  PHOTOBIOLOGY |   Topically Applied Hsp90 Inhibitor 17AAG Inhibits UVR-Induced Cutaneous Squamous Cell CarcinomasAnupama Singh,  Ashok Singh,  Jordan M Sand,  Samuel J Bauer,  Bilal Bin Hafeez,  Louise Meske and  Ajit K Verma J Invest Dermatol 2015 135: 1098-1107; advance online publication, October 22, 2014; 10.1038/jid.2014.460 Abstract | Full Text | PDF  |    |    |    |   Premature Skin Aging Features Rescued by Inhibition of NADPH Oxidase Activity in XPC-Deficient MiceMohsen Hosseini,  Walid Mahfouf,  Martin Serrano-Sanchez,  Houssam Raad,  Ghida Harfouche,  Marc Bonneu,  Stephane Claverol,  Frederic Mazurier,  Rodrigue Rossignol,  Alain Taieb and  Hamid Reza Rezvani J Invest Dermatol 2015 135: 1108-1118; advance online publication, December 1, 2014; 10.1038/jid.2014.511 Abstract | Full Text | PDF  |    |    |    |   The Circadian Clock Controls Sunburn Apoptosis and Erythema in Mouse SkinShobhan Gaddameedhi,  Christopher P Selby,  Michael G Kemp,  Rui Ye and  Aziz Sancar J Invest Dermatol 2015 135: 1119-1127; advance online publication, November 28, 2014; 10.1038/jid.2014.508 Abstract | Full Text | PDF  |    |    |    |  TUMOR BIOLOGY |   MicroRNA Expression Profiling and DNA Methylation Signature for Deregulated MicroRNA in Cutaneous T-Cell LymphomaJuan Sandoval,  Angel Díaz-Lagares,  Rocío Salgado,  Octavio Servitje,  Fina Climent,  Pablo L Ortiz-Romero,  Amparo Pérez-Ferriols,  Maria P Garcia-Muret,  Teresa Estrach,  Mar Garcia,  Lara Nonell,  Manel Esteller,  Ramon M Pujol,  Blanca Espinet and  Fernando Gallardo J Invest Dermatol 2015 135: 1128-1137; advance online publication, November 18, 2014; 10.1038/jid.2014.487 Abstract | Full Text | PDF  |    |    |    |   Assessment of Cancer Cell Line Representativeness Using Microarrays for Merkel Cell CarcinomaKenneth Daily,  Amy Coxon,  Jonathan S Williams,  Chyi-Chia R Lee,  Daniel G Coit,  Klaus J Busam and  Isaac Brownell J Invest Dermatol 2015 135: 1138-1146; advance online publication, December 18, 2014; 10.1038/jid.2014.518 Abstract | Full Text | PDF  |    |    |    |   Arsenite-Mediated Promotion of Anchorage-Independent Growth of HaCaT Cells through Placental Growth FactorIchiro Yajima,  Mayuko Y Kumasaka,  Shoko Ohnuma,  Nobutaka Ohgami,  Hisao Naito,  Hossain U Shekhar,  Yasuhiro Omata and  Masashi Kato J Invest Dermatol 2015 135: 1147-1156; advance online publication, December 10, 2014; 10.1038/jid.2014.514 Abstract | Full Text | PDF  |    |    |    |  VASCULAR BIOLOGY |   Protective Effect of MFG-E8 after Cutaneous Ischemia–Reperfusion InjuryAkihiko Uchiyama,  Kazuya Yamada,  Buddhini Perera,  Sachiko Ogino,  Yoko Yokoyama,  Yuko Takeuchi,  Osamu Ishikawa and  Sei-ichiro Motegi J Invest Dermatol 2015 135: 1157-1165; advance online publication, December 10, 2014; 10.1038/jid.2014.515 Abstract | Full Text | PDF  |    |    |    |  WOUND HEALING |   Electrical Stimulation Enhances Epidermal Proliferation in Human Cutaneous Wounds by Modulating p53–SIVA1 InteractionAnil Sebastian,  Syed A Iqbal,  James Colthurst,  Susan W Volk and  Ardeshir Bayat J Invest Dermatol 2015 135: 1166-1174; advance online publication, November 28, 2014; 10.1038/jid.2014.502 Abstract | Full Text | PDF  |    |    Letters to the Editor |  Top |    |   Characterization of Quiescent Epithelial Cells in Mouse Meibomian Glands and Hair Follicle/Sebaceous Glands by Immunofluorescence TomographyGeraint J Parfitt,  Mikhail Geyfman,  Yilu Xie and  James V Jester J Invest Dermatol 2015 135: 1175-1177; advance online publication, November 14, 2014; 10.1038/jid.2014.484 Full Text | PDF  |    |    |    |   A Single SNP Surrogate for Genotyping HLA-C*06:02 in Diverse PopulationsPhilip E Stuart,  Trilokraj Tejasvi,  Pakeeza A Shaiq,  Preya Kullavanijaya,  Raheel Qamar,  Ghazala K Raja,  Yanming Li,  John J Voorhees,  Gonçalo R Abecasis,  James T Elder and  Rajan P Nair J Invest Dermatol 2015 135: 1177-1180; advance online publication, December 10, 2014; 10.1038/jid.2014.517 Full Text | PDF  |    |    |    |   Two Birds that Exclude Each Other: The Renbök PhenomenonParadi Mirmirani J Invest Dermatol 2015 135: 1180; advance online publication, November 28, 2014; 10.1038/jid.2014.509 Full Text | PDF  |    |    |    |   Real-Time Imaging of Dendritic Cell Responses to Sterile Tissue InjuryChi Ching Goh,  Jackson LiangYao Li,  Sapna Devi,  Nadja Bakocevic,  Peter See,  Anis Larbi,  Wolfgang Weninger,  Florent Ginhoux,  Veronique Angeli and  Lai Guan Ng J Invest Dermatol 2015 135: 1181-1184; advance online publication, November 28, 2014; 10.1038/jid.2014.506 Full Text | PDF  |    |    |    |   Topical Hesperidin Enhances Epidermal Function in an Aged Murine ModelGeorge Man,  Theodora M Mauro,  Yongjiao Zhai,  Peggy L Kim,  Carolyn Cheung,  Melanie Hupe,  Debbie Crumrine,  Peter M Elias and  Mao-Qiang Man J Invest Dermatol 2015 135: 1184-1187; advance online publication, November 17, 2014; 10.1038/jid.2014.486 Full Text | PDF  |    |    |    |   A Spontaneous KRT16 Mutation in a Dog Breed: A Model for Human Focal Non-Epidermolytic Palmoplantar Keratoderma (FNEPPK)Jocelyn Plassais,  Eric Guaguère,  Laetitia Lagoutte,  Anne-Sophie Guillory,  Caroline Dufaure de Citres,  Frédérique Degorce-Rubiales,  Maxence Delverdier,  Amaury Vaysse,  Pascale Quignon,  Céline Bleuart,  Christophe Hitte,  Alain Fautrel,  Cecile Kaerle,  Pascale Bellaud,  Emmanuel Bensignor,  Guillaume Queney,  Emmanuelle Bourrat,  Anne Thomas and  Catherine André J Invest Dermatol 2015 135: 1187-1190; advance online publication, December 18, 2014; 10.1038/jid.2014.526 Full Text | PDF  |    |    |    |   More People Die from Thin Melanomas (≤1 mm) than from Thick Melanomas (>4 mm) in Queensland, AustraliaDavid C Whiteman,  Peter D Baade and  Catherine M Olsen J Invest Dermatol 2015 135: 1190-1193; advance online publication, October 20, 2014; 10.1038/jid.2014.452 Full Text | PDF  |    |    |    |   Peripheral Neuro-Immune Pathology in Recessive Dystrophic Epidermolysis BullosaMadison R Mack,  Gwen Wendelschafer-Crabb,  Brian D McAdams,  Maria K Hordinsky,  William R Kennedy and  Jakub Tolar J Invest Dermatol 2015 135: 1193-1197; advance online publication, November 14, 2014; 10.1038/jid.2014.500 Full Text | PDF  |    |    |    |   Robust Detection of Minimal Sunburn in Pigmented Skin by 785 nm Laser Speckle Contrast Imaging of Blood FluxBarbara B Shih,  Donald Allan,  Frank R de Gruijl and  Lesley E Rhodes J Invest Dermatol 2015 135: 1197-1199; advance online publication, November 28, 2014; 10.1038/jid.2014.507 Full Text | PDF  |    |    |    |   Mutation in PIGA Results in a CD52-Negative Escape Variant in a Sézary Syndrome Patient during Alemtuzumab TreatmentConstantijn J M Halkes,  Willem H Zoutman,  Leslie van der Fits,  Inge Jedema and  Maarten H Vermeer J Invest Dermatol 2015 135: 1199-1202; advance online publication, November 28, 2014; 10.1038/jid.2014.501 Full Text | PDF  |    |    |    |   	 	 	 	   	Please note that you need to be a subscriber or site-license holder to enjoy full-text access to The Journal of Investigative Dermatology. 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