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Molecular Therapy - Table of Contents alert Volume 23 Issue 2

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Molecular Therapy
TABLE OF CONTENTS

Volume 23, Issue 2 (February 2015)

In this issue
Editorial
In This Issue
Research Highlights
Commentaries
Original Articles
Corrigendum

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Molecular Therapy- Oncolytics is an online-only, open access journal, focusing on the development and clinical testing of viral, cellular, and other biological therapies targeting cancer.

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Editorial

Top

Glybera’s Second Act: The Curtain Rises on the High Cost of Therapy

Seppo Ylä-Herttuala

Mol Ther 2015 23: 217-218; 10.1038/mt.2014.248

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In This Issue

Top

In This Issue

Mol Ther 2015 23: 220; 10.1038/mt.2014.249

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Research Highlights

Top

Research Highlights

Mol Ther 2015 23: 221; 10.1038/mt.2014.250

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Commentaries

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Therapeutic Implications of Orally Delivered Immunomodulatory Oligonucleotides

Dennis M Klinman

Mol Ther 2015 23: 222-223; 10.1038/mt.2014.251

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Extending Flaps Lifts an Infarcted Heart Toward Repair

Gianni Angelini, Massimo Caputo and Paolo Madeddu

Mol Ther 2015 23: 223-225; 10.1038/mt.2014.252

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Original Articles

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AAV2 Delivery of Flt23k Intraceptors Inhibits Murine Choroidal Neovascularization

Xiaohui Zhang, Subrata K Das, Samuel F Passi, Hironori Uehara, Austin Bohner, Marcus Chen, Michelle Tiem, Bonnie Archer and Balamurali K Ambati

Mol Ther 2015 23: 226-234; advance online publication, October 13, 2014; 10.1038/mt.2014.199

Abstract | Full Text

Antiangiogenic Variant of TSP-1 Targets Tumor Cells in Glioblastomas

Sung Hugh Choi, Kaoru Tamura, Rajiv Kumar Khajuria, Deepak Bhere, Irina Nesterenko, Jack Lawler and Khalid Shah

Mol Ther 2015 23: 235-243; advance online publication, October 31, 2014; 10.1038/mt.2014.214

Abstract | Full Text

Enhanced Efficacy of the CDNF/MANF Family by Combined Intranigral Overexpression in the 6-OHDA Rat Model of Parkinson’s Disease

Óscar Cordero-Llana, Benjamin C Houghton, Federica Rinaldi, Hannah Taylor, Rafael J Yáñez-Muñoz, James B Uney, Liang-Fong Wong and Maeve A Caldwell

Mol Ther 2015 23: 244-254; advance online publication, November 5, 2014; 10.1038/mt.2014.206

Abstract | Full Text

Exosome-mediated Delivery of the Intrinsic C-terminus Domain of PTEN Protects It From Proteasomal Degradation and Ablates Tumorigenesis

Syed Feroj Ahmed, Nilanjana Das, Moumita Sarkar, Uttara Chatterjee, Sandip Chatterjee and Mrinal Kanti Ghosh

Mol Ther 2015 23: 255-269; advance online publication, October 20, 2014; 10.1038/mt.2014.202

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PTEN Depletion Decreases Disease Severity and Modestly Prolongs Survival in a Mouse Model of Spinal Muscular AtrophyMTOPEN

Daniel Little, Chiara F Valori, Chantal A Mutsaers, Ellen J Bennett, Matthew Wyles, Basil Sharrack, Pamela J Shaw, Thomas H Gillingwater, Mimoun Azzouz and Ke Ning

Mol Ther 2015 23: 270-277; advance online publication, November 5, 2014; 10.1038/mt.2014.209

Abstract | Full Text

Cyclooxygenase-2 Silencing for the Treatment of Colitis: A Combined In Vivo Strategy Based on RNA Interference and Engineered Escherichia Coli

Enzo Spisni, Maria C Valerii, Luigia De Fazio, Elena Cavazza, Francesca Borsetti, Annamaria Sgromo, Marco Candela, Manuela Centanni, Fernando Rizello and Antonio Strillacci

Mol Ther 2015 23: 278-289; advance online publication, November 13, 2014; 10.1038/mt.2014.222

Abstract | Full Text

The Expression Pattern of Systemically Injected AAV9 in the Developing Mouse Retina Is Determined by Age

Leah C Byrne, Yvonne J Lin, Trevor Lee, David V Schaffer and John G Flannery

Mol Ther 2015 23: 290-296; advance online publication, September 16, 2014; 10.1038/mt.2014.181

Abstract | Full Text

Inhibitory/Suppressive Oligodeoxynucleotide Nanocapsules as Simple Oral Delivery Devices for Preventing Atopic Dermatitis in Mice

Yeqin Wang, Yoshinari Yamamoto, Suguru Shigemori, Takafumi Watanabe, Kazushi Oshiro, Xinyu Wang, Pengfei Wang, Takashi Sato, Shinichi Yonekura, Sachi Tanaka, Haruki Kitazawa and Takeshi Shimosato

Mol Ther 2015 23: 297-309; advance online publication, December 15, 2014; 10.1038/mt.2014.239

Abstract | Full Text

Multiplexing Seven miRNA-Based shRNAs to Suppress HIV Replication

Jang-Gi Choi, Preeti Bharaj, Sojan Abraham, Hongming Ma, Guohua Yi, Chunting Ye, Ying Dang, N Manjunath, Haoquan Wu and Premlata Shankar

Mol Ther 2015 23: 310-320; advance online publication, October 31, 2014; 10.1038/mt.2014.205

Abstract | Full Text

Case–Control Estimation of the Impact of Oncolytic Adenovirus on the Survival of Patients With Refractory Solid Tumors

Anna Kanerva, Anniina Koski, Ilkka Liikanen, Minna Oksanen, Timo Joensuu, Otto Hemminki, Juni Palmgren, Kari Hemminki and Akseli Hemminki

Mol Ther 2015 23: 321-329; advance online publication, November 10, 2014; 10.1038/mt.2014.218

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Selective Inhibition of Tumor Growth by Clonal NK Cells Expressing an ErbB2/HER2-Specific Chimeric Antigen Receptor

Kurt Schönfeld, Christiane Sahm, Congcong Zhang, Sonja Naundorf, Christian Brendel, Marcus Odendahl, Paulina Nowakowska, Halvard Bönig, Ulrike Köhl, Stephan Kloess, Sylvia Köhler, Heidi Holtgreve-Grez, Anna Jauch, Manfred Schmidt, Ralf Schubert, Klaus Kühlcke, Erhard Seifried, Hans G Klingemann, Michael A Rieger, Torsten Tonn, Manuel Grez and Winfried S Wels

Mol Ther 2015 23: 330-338; advance online publication, November 6, 2014; 10.1038/mt.2014.219

Abstract | Full Text

Targeted 25-hydroxyvitamin D3 1α-hydroxylase Adoptive Gene Therapy Ameliorates DSS-induced Colitis Without Causing Hypercalcemia in Mice

Bo Li, David J Baylink, Michael H Walter, Kin-Hing William Lau, Xianmei Meng, Jun Wang, Andriy Cherkas, Xiaolei Tang and Xuezhong Qin

Mol Ther 2015 23: 339-351; advance online publication, October 20, 2014; 10.1038/mt.2014.201

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Cyclosporin A and Rapamycin Relieve Distinct Lentiviral Restriction Blocks in Hematopoietic Stem and Progenitor Cells

Carolina Petrillo, Daniela Cesana, Francesco Piras, Sara Bartolaccini, Luigi Naldini, Eugenio Montini and Anna Kajaste-Rudnitski

Mol Ther 2015 23: 352-362; advance online publication, October 1, 2014; 10.1038/mt.2014.193

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Implantation of rAAV5-IGF-I Transduced Autologous Chondrocytes Improves Cartilage Repair in Full-thickness Defects in the Equine Model

Kyla F Ortved, Laila Begum, Hussni O Mohammed and Alan J Nixon

Mol Ther 2015 23: 363-373; advance online publication, October 14, 2014; 10.1038/mt.2014.198

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Cell-sheet Therapy With Omentopexy Promotes Arteriogenesis and Improves Coronary Circulation Physiology in Failing Heart

Satoshi Kainuma, Shigeru Miyagawa, Satsuki Fukushima, James Pearson, Yi Ching Chen, Atsuhiro Saito, Akima Harada, Motoko Shiozaki, Hiroko Iseoka, Tadashi Watabe, Hiroshi Watabe, Genki Horitsugi, Mana Ishibashi, Hayato Ikeda, Hirotsugu Tsuchimochi, Takashi Sonobe, Yutaka Fujii, Hisamichi Naito, Keiji Umetani, Tatsuya Shimizu, Teruo Okano, Eiji Kobayashi, Takashi Daimon, Takayoshi Ueno, Toru Kuratani, Koichi Toda, Nobuyuki Takakura, Jun Hatazawa, Mikiyasu Shirai and Yoshiki Sawa

Mol Ther 2015 23: 374-386; advance online publication, November 25, 2014; 10.1038/mt.2014.225

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Broadly-specific Cytotoxic T Cells Targeting Multiple HIV Antigens Are Expanded From HIV+ Patients: Implications for Immunotherapy

Sharon Lam, Julia Sung, Conrad Cruz, Paul Castillo-Caro, Minhtran Ngo, Carolina Garrido, Joann Kuruc, Nancie Archin, Cliona Rooney, David Margolis and Catherine Bollard

Mol Ther 2015 23: 387-395; advance online publication, November 4, 2014; 10.1038/mt.2014.207

Abstract | Full Text

Recurrence of Melanoma Following T Cell Treatment: Continued Antigen Expression in a Tumor That Evades T Cell Recruitment

Trudy Straetemans, Cor Berrevoets, Miriam Coccoris, Elike Treffers-Westerlaken, Rebecca Wijers, David K Cole, Valerie Dardalhon, Andrew K Sewell, Naomi Taylor, Jaap Verweij and Reno Debets

Mol Ther 2015 23: 396-406; advance online publication, November 3, 2014; 10.1038/mt.2014.215

Abstract | Full Text

Corrigendum

Top

Corrigendum to “Exosome-mediated Delivery of the Intrinsic C-terminus Domain of PTEN Protects It From Proteasomal Degradation and Ablates Tumorigenesis”

Mol Ther 2015 23: 407; 10.1038/mt.2014.238

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Corrigendum to “A Novel Chimeric Adenoassociated Virus 2/Human Bocavirus 1 Parvovirus Vector Efficiently Transduces Human Airway Epithelia”

Mol Ther 2015 23: 407; 10.1038/mt.2014.237

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