Molecular Therapy Podcast In this podcast, Dr. Malcolm Brenner (Editor-in-Chief, Molecular Therapy) and Dr. Yuman Fong (Editor-in-Chief, Molecular Therapy - Oncolytics) discuss MTO's upcoming launch in December 2014. They explain how MTO will fit into the MT family and provide a unique forum for work in the fields of oncolytic virotherapy and T cell-based therapies. | |
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|  | | | Editorial | Top |  | Where Is the Good in Goodbye?Malcolm K Brenner Mol Ther 2014 22: 1873-1874; 10.1038/mt.2014.184 Full Text |  | In This Issue | Top |  | In This IssueMol Ther 2014 22: 1876; 10.1038/mt.2014.185 Full Text |  | Research Highlights | Top |  | Research HighlightsMol Ther 2014 22: 1877; 10.1038/mt.2014.186 Full Text |  | Letter to the Editor | Top |  | Long-Term Skin Regeneration From a Gene-Targeted Human Epidermal Stem Cell CloneBlanca Duarte, Francesca Miselli, Rodolfo Murillas, Luis Espinosa-Hevia, Juan Cruz Cigudosa, Alessandra Recchia, Marcela Del Río and Fernando Larcher Mol Ther 2014 22: 1878-1880; 10.1038/mt.2014.187 Full Text |  | Commentaries | Top |  | How To Train Your Oncolytic Virus: the Immunological SequelRichard G Vile Mol Ther 2014 22: 1881-1884; 10.1038/mt.2014.188 Full Text |  |  |  | Could Exon Skipping Help Dystrophic Boys to Run, Hop, and Jump?Terence Partridge Mol Ther 2014 22: 1884-1886; 10.1038/mt.2014.189 Full Text |  |  |  | A Theranostic “SMART” Aptamer for Targeted Therapy of Prostate CancerVittorio de Franciscis Mol Ther 2014 22: 1886-1888; 10.1038/mt.2014.190 Full Text |  |  |  | MSCs Isolated From Patients With Ischemic Vascular Disease Have Normal Angiogenic PotentialClara Sanz-Nogués and Timothy O'Brien Mol Ther 2014 22: 1888-1889; 10.1038/mt.2014.191 Full Text |  | Original Articles | Top |  | Muscle and Heart Function Restoration in a Limb Girdle Muscular Dystrophy 2I (LGMD2I) Mouse Model by Systemic FKRP Gene DeliveryChunping Qiao, Chi-Hsien Wang, Chunxia Zhao, Peijuan Lu, Hiroyuki Awano, Bin Xiao, Jianbin Li, Zhenhua Yuan, Yi Dai, Carrie Bette Martin, Juan Li, Qilong Lu and Xiao Xiao Mol Ther 2014 22: 1890-1899; advance online publication, July 22, 2014; 10.1038/mt.2014.141 Abstract | Full Text |  |  |  | Vector Design Tour de Force: Integrating Combinatorial and Rational Approaches to Derive Novel Adeno-associated Virus VariantsDamien Marsic, Lakshmanan Govindasamy, Seth Currlin, David M Markusic, Yu-Shan Tseng, Roland W Herzog, Mavis Agbandje-McKenna and Sergei Zolotukhin Mol Ther 2014 22: 1900-1909; advance online publication, July 22, 2014; 10.1038/mt.2014.139 Abstract | Full Text |  |  |  | Targeted Inhibition of Prostate Cancer Metastases with an RNA Aptamer to Prostate-specific Membrane AntigenMTOPENJustin P Dassie, Luiza I Hernandez, Gregory S Thomas, Matthew E Long, William M Rockey, Craig A Howell, Yani Chen, Frank J Hernandez, Xiu Ying Liu, Mary E Wilson, Lee-Ann Allen, Daniel A Vaena, David K Meyerholz and Paloma H Giangrande Mol Ther 2014 22: 1910-1922; advance online publication, June 23, 2014; 10.1038/mt.2014.117 Abstract | Full Text |  |  |  | Forelimb Treatment in a Large Cohort of Dystrophic Dogs Supports Delivery of a Recombinant AAV for Exon Skipping in Duchenne PatientsCaroline Le Guiner, Marie Montus, Laurent Servais, Yan Cherel, Virginie Francois, Jean-Laurent Thibaud, Claire Wary, Béatrice Matot, Thibaut Larcher, Lydie Guigand, Maeva Dutilleul, Claire Domenger, Marine Allais, Maud Beuvin, Amélie Moraux, Johanne Le Duff, Marie Devaux, Nicolas Jaulin, Mickaël Guilbaud, Virginie Latournerie, Philippe Veron, Sylvie Boutin, Christian Leborgne, Diana Desgue, Jack-Yves Deschamps, Sophie Moullec, Yves Fromes, Adeline Vulin, Richard H Smith, Nicolas Laroudie, Frédéric Barnay-Toutain, Christel Rivière, Stéphanie Bucher, Thanh-Hoa Le, Nicolas Delaunay, Mehdi Gasmi, Robert M Kotin, Gisèle Bonne, Oumeya Adjali, Carole Masurier, Jean-Yves Hogrel, Pierre Carlier, Philippe Moullier and Thomas Voit Mol Ther 2014 22: 1923-1935; advance online publication, August 4, 2014; 10.1038/mt.2014.151 Abstract | Full Text |  |  |  | The Profile of Tumor Antigens Which Can be Targeted by Immunotherapy Depends Upon the Tumor’s Anatomical SiteVanesa Alonso-Camino, Karishma Rajani, Timothy Kottke, Diana Rommelfanger-Konkol, Shane Zaidi, Jill Thompson, Jose Pulido, Elizabeth Ilett, Oliver Donnelly, Peter Selby, Hardev Pandha, Alan Melcher, Kevin Harrington, Rosa Maria Diaz and Richard Vile Mol Ther 2014 22: 1936-1948; advance online publication, July 25, 2014; 10.1038/mt.2014.134 Abstract | Full Text |  |  |  | CTLA-4 and PD-L1 Checkpoint Blockade Enhances Oncolytic Measles Virus TherapyChristine E Engeland, Christian Grossardt, Rūta Veinalde, Sascha Bossow, Diana Lutz, Johanna K Kaufmann, Ivan Shevchenko, Viktor Umansky, Dirk M Nettelbeck, Wilko Weichert, Dirk Jäger, Christof von Kalle and Guy Ungerechts Mol Ther 2014 22: 1949-1959; advance online publication, August 26, 2014; 10.1038/mt.2014.160 Abstract | Full Text |  |  |  | Neovascularization Capacity of Mesenchymal Stromal Cells From Critical Limb Ischemia Patients Is Equivalent to Healthy ControlsHendrik Gremmels, Martin Teraa, Paul HA Quax, Krista den Ouden, Joost O Fledderus and Marianne C Verhaar Mol Ther 2014 22: 1960-1970; advance online publication, September 1, 2014; 10.1038/mt.2014.161 Abstract | Full Text |  |  |  | Lentiviral Arrays for Live-cell Dynamic Monitoring of Gene and Pathway Activity During Stem Cell DifferentiationRoshan M Padmashali, Panagiotis Mistriotis, Mao-shih Liang and Stelios T Andreadis Mol Ther 2014 22: 1971-1982; advance online publication, June 4, 2014; 10.1038/mt.2014.103 Abstract | Full Text |  |  |  | RNAi-mediated TCR Knockdown Prevents Autoimmunity in Mice Caused by Mixed TCR Dimers Following TCR Gene TransferMario Bunse, Gavin M Bendle, Carsten Linnemann, Laura Bies, Stephan Schulz, Ton N Schumacher and Wolfgang Uckert Mol Ther 2014 22: 1983-1991; advance online publication, July 22, 2014; 10.1038/mt.2014.142 Abstract | Full Text |  |  |  | Translating the Immunogenicity of Prime-boost Immunization With ChAd63 and MVA ME-TRAP From Malaria Naive to Malaria-endemic PopulationsDomtila Kimani, Ya Jankey Jagne, Momodou Cox, Eva Kimani, Carly M Bliss, Evelyn Gitau, Caroline Ogwang, Muhammed O Afolabi, Georgina Bowyer, Katharine A Collins, Nick Edwards, Susanne H Hodgson, Christopher J A Duncan, Alexandra J Spencer, Miguel G Knight, Abdoulie Drammeh, Nicholas A Anagnostou, Eleanor Berrie, Sarah Moyle, Sarah C Gilbert, Peninah Soipei, Joseph Okebe, Stefano Colloca, Riccardo Cortese, Nicola K Viebig, Rachel Roberts, Alison M Lawrie, Alfredo Nicosia, Egeruan B Imoukhuede, Philip Bejon, Roma Chilengi, Kalifa Bojang, Katie L Flanagan, Adrian V S Hill, Britta C Urban and Katie J Ewer Mol Ther 2014 22: 1992-2003; advance online publication, June 16, 2014; 10.1038/mt.2014.109 Abstract | Full Text |  |  |  | A Chaperone Enhances Blood α-Glucosidase Activity in Pompe Disease Patients Treated With Enzyme Replacement TherapyGiancarlo Parenti, Simona Fecarotta, Giancarlo la Marca, Barbara Rossi, Serena Ascione, Maria Alice Donati, Lucia Ovidia Morandi, Sabrina Ravaglia, Anna Pichiecchio, Daniela Ombrone, Michele Sacchini, Maria Barbara Pasanisi, Paola De Filippi, Cesare Danesino, Roberto Della Casa, Alfonso Romano, Carmine Mollica, Margherita Rosa, Teresa Agovino, Edoardo Nusco, Caterina Porto and Generoso Andria Mol Ther 2014 22: 2004-2012; advance online publication, July 23, 2014; 10.1038/mt.2014.138 Abstract | Full Text |  | Corrigendum | Top |  | Corrigendum to “Proapoptotic Peptide-Mediated Cancer Therapy Targeted to Cell Surface p32”Mol Ther 2014 22: 2013; 10.1038/mt.2014.136 Full Text |  | Erratum | Top |  | Erratum to “Hyperactive PiggyBac Transposons for Sustained and Robust Liver-targeted Gene Therapy”Mol Ther 2014 22: 2013; 10.1038/mt.2014.182 Full Text |  |  |  | Erratum to “Lentiviral Arrays for Live-cell Dynamic Monitoring of Gene and Pathway Activity During Stem Cell Differentiation”Mol Ther 2014 22: 2013; 10.1038/mt.2014.158 Full Text |  |  |  |  | | Advertisement |  | | Submit to Molecular Therapy — Methods & Clinical Development (MTM), a new addition to the Molecular Therapy family of journals. 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