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TABLE OF CONTENTS
|  |  |  | Volume 96, Issue 4 (October 2014) |  | In this issue In This Issue Editorial News & Views Perspectives CPIC Update Clinical Trial State of the Art Review Research
| |  |  | In This Issue | Top |  | In This IssueClin Pharmacol Ther 2014 96: 399; 10.1038/clpt.2014.161 Full Text |  | Editorial | Top |  | Inflammation: The Dynamic Force of Health and DiseaseV Vassileva and M Piquette-Miller Clin Pharmacol Ther 2014 96: 401-405; 10.1038/clpt.2014.150 Abstract | Full Text |  | News & Views | Top |  | HIGHLIGHTS | HighlightsClin Pharmacol Ther 2014 96: 406-407; 10.1038/clpt.2014.160 Full Text |  |  |  | ASCPT NEWS | ASCPT NewsClin Pharmacol Ther 2014 96: 408-411; 10.1038/clpt.2014.157 Full Text |  | Perspectives | Top |  | POINT-COUNTERPOINT | Impact of Modeling and Simulation: Myth or Fact?S R B Allerheiligen Clin Pharmacol Ther 2014 96: 413-415; 10.1038/clpt.2014.122 Full Text |  |  |  | What Happened to the Modeling and Simulation Revolution?P L Bonate Clin Pharmacol Ther 2014 96: 416-417; 10.1038/clpt.2014.123 Full Text |  |  |  | COMMENTARY | Human Endotoxin Administration as an Experimental Model in Drug DevelopmentA F Suffredini and R J Noveck Clin Pharmacol Ther 2014 96: 418-422; 10.1038/clpt.2014.146 Abstract | Full Text |  | CPIC Update | Top |  | The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1 and Simvastatin-Induced Myopathy: 2014 UpdateL B Ramsey, S G Johnson, K E Caudle, C E Haidar, D Voora, R A Wilke, W D Maxwell, H L McLeod, R M Krauss, D M Roden, Q Feng, R M Cooper-DeHoff, L Gong, T E Klein, M Wadelius and M Niemi Clin Pharmacol Ther 2014 96: 423-428; advance online publication, June 11, 2014; 10.1038/clpt.2014.125 Abstract | Full Text |  | Clinical Trial | Top |  | Use of Opportunistic Clinical Data and a Population Pharmacokinetic Model to Support Dosing of Clindamycin for Premature Infants to AdolescentsD Gonzalez, C Melloni, R Yogev, B B Poindexter, S R Mendley, P Delmore, J E Sullivan, J Autmizguine, A Lewandowski, B Harper, K M Watt, K C Lewis, E V Capparelli, D K Benjamin, Jr and M Cohen-Wolkowiez on behalf of the Best Pharmaceuticals for Children Act – Pediatric Trials Network Administrative Core Committee Clin Pharmacol Ther 2014 96: 429-437; advance online publication, June 20, 2014; 10.1038/clpt.2014.134 Abstract | Full Text |  |  |  | Pulmonary Penetration of Piperacillin and Tazobactam in Critically Ill PatientsT W Felton, K McCalman, I Malagon, B Isalska, S Whalley, J Goodwin, A M Bentley and W W Hope Clin Pharmacol Ther 2014 96: 438-448; advance online publication, June 13, 2014; 10.1038/clpt.2014.131 Abstract | Full Text |  | State of the Art | Top |  | Cancer, Inflammation, and Therapy: Effects on Cytochrome P450–Mediated Drug Metabolism and Implications for Novel Immunotherapeutic AgentsR Donald Harvey and E T Morgan Clin Pharmacol Ther 2014 96: 449-457; advance online publication, July 2, 2014; 10.1038/clpt.2014.143 Abstract | Full Text |  |  |  | Obesity and Resistance to Cancer Chemotherapy: Interacting Roles of Inflammation and Metabolic DysregulationL M Lashinger, E L Rossi and S D Hursting Clin Pharmacol Ther 2014 96: 458-463; advance online publication, June 24, 2014; 10.1038/clpt.2014.136 Abstract | Full Text |  | Review | Top |  | Longitudinal Inflammation, Cognitive Decline, and Alzheimer’s Disease: A Mini-ReviewB M Bettcher and J H Kramer Clin Pharmacol Ther 2014 96: 464-469; advance online publication, July 10, 2014; 10.1038/clpt.2014.147 Abstract | Full Text |  |  |  | Phenotype Standardization for Statin-Induced Myotoxicity OPENA Alfirevic, D Neely, J Armitage, H Chinoy, R G Cooper, R Laaksonen, D F Carr, K M Bloch, J Fahy, A Hanson, Q-Y Yue, M Wadelius, A H Maitland-van Der Zee, D Voora, B M Psaty, C N A Palmer and M Pirmohamed Clin Pharmacol Ther 2014 96: 470-476; advance online publication, June 4, 2014; 10.1038/clpt.2014.121 Abstract | Full Text |  |  |  | Phenotype Standardization of Angioedema in the Head and Neck Region Caused by Agents Acting on the Angiotensin System OPENM Wadelius, S E Marshall, G Islander, L Nordang, M Karawajczyk, Q-Y Yue, I Terreehorst, E V Baranova, S Hugosson, K Sköldefors, M Pirmohamed, A-H Maitland-van der Zee, A Alfirevic, P Hallberg and C N A Palmer Clin Pharmacol Ther 2014 96: 477-481; advance online publication, June 24, 2014; 10.1038/clpt.2014.138 Abstract | Full Text |  | Research | Top |  | ARTICLES | Design and Anticipated Outcomes of the eMERGE-PGx Project: A Multicenter Pilot for Preemptive Pharmacogenomics in Electronic Health Record SystemsL J Rasmussen-Torvik, S C Stallings, A S Gordon, B Almoguera, M A Basford, S J Bielinski, A Brautbar, M H Brilliant, D S Carrell, J J Connolly, D R Crosslin, K F Doheny, C J Gallego, O Gottesman, D S Kim, K A Leppig, R Li, S Lin, S Manzi, A R Mejia, J A Pacheco, V Pan, J Pathak, C L Perry, J F Peterson, C A Prows, J Ralston, L V Rasmussen, M D Ritchie, S Sadhasivam, S A Scott, M Smith, A Vega, A A Vinks, S Volpi, W A Wolf, E Bottinger, R L Chisholm, C G Chute, J L Haines, J B Harley, B Keating, I A Holm, I J Kullo, G P Jarvik, E B Larson, T Manolio, C A McCarty, D A Nickerson, S E Scherer, M S Williams, D M Roden and J C Denny Clin Pharmacol Ther 2014 96: 482-489; advance online publication, June 24, 2014; 10.1038/clpt.2014.137 Abstract | Full Text |  |  |  | Antipsychotics and Associated Risk of Out-of-Hospital Cardiac ArrestP Weeke, A Jensen, F Folke, G H Gislason, J B Olesen, E L Fosbøl, M Wissenberg, F K Lippert, E F Christensen, S L Nielsen, E Holm, J K Kanters, H E Poulsen, L Køber and C Torp-Pedersen Clin Pharmacol Ther 2014 96: 490-497; advance online publication, June 24, 2014; 10.1038/clpt.2014.139 Abstract | Full Text |  |  |  | Glucuronidation Converts Clopidogrel to a Strong Time-Dependent Inhibitor of CYP2C8: A Phase II Metabolite as a Perpetrator of Drug–Drug InteractionsA Tornio, A M Filppula, O Kailari, M Neuvonen, T H Nyrönen, T Tapaninen, P J Neuvonen, M Niemi and J T Backman Clin Pharmacol Ther 2014 96: 498-507; advance online publication, June 27, 2014; 10.1038/clpt.2014.141 Abstract | Full Text |  |  |  | Exposure to Mycophenolic Acid Better Predicts Immunosuppressive Efficacy Than Exposure to Calcineurin Inhibitors in Renal Transplant PatientsZ Daher Abdi, A Prémaud, M Essig, S Alain, E Munteanu, F Garnier, Y Le Meur, P Marquet and A Rousseau Clin Pharmacol Ther 2014 96: 508-515; advance online publication, June 26, 2014; 10.1038/clpt.2014.140 Abstract | Full Text |  |  |  | Please note that you need to be a subscriber or site-license holder to enjoy full-text access to Clinical Pharmacology & Therapeutics. 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