Wednesday, August 20, 2014

Nature Reviews Neuroscience contents September 2014 Volume 15 Number 9 pp 563-627

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Nature Reviews Neuroscience

 
TABLE OF CONTENTS
 
September 2014 Volume 15 Number 9
Nature Reviews Neuroscience cover
Impact Factor 31.376 *
In this issue
Research Highlights
Progress
Reviews
Perspectives

Also this month
 Featured article:
Peripheral thermosensation in mammals
Joris Vriens, Bernd Nilius & Thomas Voets


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RESEARCH HIGHLIGHTS
Top

Metabolism: Sugar on the brain
p563 | doi:10.1038/nrn3812
High levels of central transforming growth factor-β1 induce hypothalamic inflammation and lead to hyperglycaemia and glucose intolerance.

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Synaptic plasticity: A homeostatic messenger
p564 | doi:10.1038/nrn3808
Endostatin acts as a trans-synaptic signal to promote presynaptic homeostasis at the fly neuromuscular junction.

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Neural circuits: Putting a stop to feeding
p564 | doi:10.1038/nrn3809
A subpopulation of neurons in a subdivision of the central amygdala have been found to mediate diverse anorexigenic signals.

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Neurodegenerative disease: Propagating pathology
p565 | doi:10.1038/nrn3802
Mutant huntingtin pathology is shown to propagate between neurons and contribute to neurodegeneration.

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Oscillations: A dynamic role for astrocytes
p566 | doi:10.1038/nrn3810
Astrocytes contribute to the maintenance of fast synchronous activity in the hippocampus and have a role in recognition memory.

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IN BRIEF

Reward: Loving food too much | Synaptic plasticity: Motility movers and shakers | Neurodevelopmental disorders: Brain–gut connection in autism? | Neurodegenerative disease: Faulty splicing in Huntington's disease | Sensory processing: Mixed-up mitral cells | Pain: Finding motivation in pain | Ageing: Synaptic slide into old age | Decision making: Off the hook
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Neuroscience
JOBS of the week
Assistant Professor - Behavioral Neuroscience
Villanova University
Faculty Position in Neuroscience
The Stowers Institute for Medical Research
PhD Scholarship in Behavioral Neuroscience
Duke-NUS Graduate Medical School (Singapore)
Postdoctoral Fellow in Developmental Neuroscience
Children's National Medical Center
Lab Technician in Neuroscience and Metabolism (Baylor College of Medicine)
Baylor College of Medicine (BCM)
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PROGRESS
Top
Localized GABAergic inhibition of dendritic Ca2+ signalling
Michael J. Higley
p567 | doi:10.1038/nrn3803
Inhibitory GABAergic synapses on dendritic spines and shafts have a key role in the localized regulation of neuronal Ca2+ signalling. In this Progress article, Higley explains how the influences of dendritic inhibition on electrical and biochemical activity in neurons shape synaptic plasticity.

Abstract | Full Text | PDF
 
REVIEWS
Top
Peripheral thermosensation in mammals
Joris Vriens, Bernd Nilius & Thomas Voets
p573 | doi:10.1038/nrn3784
The ability of sensory neurons to sense temperature is dependent on thermosensitive ion channels. In this Review, Voets and colleagues examine the ion channels — notably, the transient receptor potential cation channels — that have been implicated in the detection of temperature in mammals.
Abstract | Full Text | PDF

Fly visual course control: behaviour, algorithms and circuits
Alexander Borst
p590 | doi:10.1038/nrn3799
Recent developments in genetic techniques and monitoring neuronal activity are allowing the roles of different neurons in various fly behaviours to be probed. In light of this progress, Alexander Borst reviews the neuronal circuits underlying visual course control in Drosophila melanogaster.
Abstract | Full Text | PDF

Integrating the active process of hair cells with cochlear function
A. J. Hudspeth
600 | doi:10.1038/nrn3786
The sensitivity, frequency resolution and dynamic range of hearing depend upon the cochlear active process, a mechanical-amplification system within the cochlea. In this Review, Hudspeth summarizes evidence that these features result from the operation of hair cells near a dynamical instability, the Hopf bifurcation.
Abstract | Full Text | PDF

 
PERSPECTIVES
Top
OPINION
Intrinsically different retinal progenitor cells produce specific types of progeny
Connie Cepko
p615 | doi:10.1038/nrn3767
Retinal progenitor cells (RPCs) produce all of the retina's cells through an evolutionarily conserved series of divisions and cell fate decisions. In this article, Cepko describes recent studies that have shed light on the intrinsic and extrinsic mechanisms that drive this process and argues that individual terminally dividing RPCs are molecularly specified to produce particular progeny.
Abstract | Full Text | PDF | Supplementary information

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