Scientific Reports Biology Table of Contents e-alert: 22 April 2014

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22 April 2014      • Visit Scientific Reports • Submit your manuscript to Scientific Reports     Welcome to your Table of Contents e-alert for Scientific Reports               Biological Sciences               Chemical Modulation of the Biological Activity of Reutericyclin: a Membrane-Active Antibiotic from Lactobacillusreuteri ▶     Philip T. Cherian, Xiaoqian Wu, Marcus M. Maddox et al.     Whilst the development of membrane-active antibiotics is now an attractive therapeutic concept, progress in this area is disadvantaged by poor knowledge of the structure-activity …             Logging Concessions Enable Illegal Logging Crisis in the Peruvian Amazon ▶     Matt Finer, Clinton N. Jenkins, Melissa A. Blue Sky et al.     The Peruvian Amazon is an important arena in global efforts to promote sustainable logging in the tropics. Despite recent efforts to achieve sustainability, such as provisions in …             Integrating reductive and synthetic approaches in biology using man-made cell-like compartments ▶     Wataru Aoki, Masato Saito, Ri-ichiroh Manabe et al.     We propose ‘integrated synthetic genetics’ as a novel methodology that integrates reductive and synthetic approaches used in life science research. Integrated synthetic genetics …             Origin of subdiffusion of water molecules on cell membrane surfaces ▶     Eiji Yamamoto, Takuma Akimoto, Masato Yasui et al.     Water molecules play an important role in providing unique environments for biological reactions on cell membranes. It is widely believed that water molecules form bridges that …             Gellan sulfate inhibits Plasmodium falciparum growth and invasion of red blood cells in vitro ▶     Frances Cagayat Recuenco, Kyousuke Kobayashi, Akiko Ishiwa et al.     Here, we assessed the sulfated derivative of the microbial polysaccharide gellan gum and derivatives of λ and κ-carrageenans for their ability to inhibit Plasmodium falciparum 3D7 …             Automated single-cell motility analysis on a chip using lensfree microscopy ▶     Ivan Pushkarsky, Yunbo Lyb, Westbrook Weaver et al.     Quantitative cell motility studies are necessary for understanding biophysical processes, developing models for cell locomotion and for drug discovery. Such studies are typically …             Enhancement mechanisms of graphene in nano-58S bioactive glass scaffold: mechanical and biological performance ▶     Chengde Gao, Tingting Liu, Cijun Shuai et al.     Graphene is a novel material and currently popular as an enabler for the next-generation nanocomposites. Here, we report the use of graphene to improve the mechanical properties …             Absence of CD9 reduces endometrial VEGF secretion and impairs uterine repair after parturition ▶     Natsuko Kawano, Kenji Miyado, Noriko Yoshii et al.     In mammals, uterine epithelium is remodeled cyclically throughout adult life for pregnancy. Despite the expression of CD9 in the uterine epithelium, its role in maternal …             Nitroheterocyclic compounds are more efficacious than CYP51 inhibitors against Trypanosoma cruzi: implications for Chagas disease drug discovery and development ▶     Carolina B. Moraes, Miriam A. Giardini, Hwayoung Kim et al.     Advocacy for better drugs and access to treatment has boosted the interest in drug discovery and development for Chagas disease, a chronic infection caused by the genetically …             ASK1 promotes the contact hypersensitivity response through IL-17 production ▶     Junya Mizukami, Takehiro Sato, Montserrat Camps et al.     Contact hypersensitivity (CHS) is a form of delayed-type hypersensitivity triggered by the response to reactive haptens (sensitization) and subsequent challenge (elicitation). …             Phylogenetic variation of phytolith carbon sequestration in bamboos ▶     Beilei Li, Zhaoliang Song, Zimin Li et al.     Phytoliths, the amorphous silica deposited in plant tissues, can occlude organic carbon (phytolith-occluded carbon, PhytOC) during their formation and play a significant role in …             Cell death stages in single apoptotic and necrotic cells monitored by Raman microspectroscopy ▶     Eva Brauchle, Sibylle Thude, Sara Y. Brucker et al.     Although apoptosis and necrosis have distinct features, the identification and discrimination of apoptotic and necrotic cell death in vitro is challenging. Immunocytological and …             Immature visual neural system in children reflected by contrast sensitivity with adaptive optics correction ▶     Rong Liu, Jiawei Zhou, Haoxin Zhao et al.     This study aimed to explore the neural development status of the visual system of children (around 8 years old) using contrast sensitivity. We achieved this by eliminating the …             The Acyclic Retinoid Peretinoin Inhibits Hepatitis C Virus Replication and Infectious Virus Release in Vitro ▶     Tetsuro Shimakami, Masao Honda, Takayoshi Shirasaki et al.     Clinical studies suggest that the oral acyclic retinoid Peretinoin may reduce the recurrence of hepatocellular carcinoma (HCC) following surgical ablation of primary tumours. …             Brain microvascular endothelial cells resist elongation due to curvature and shear stress ▶     Mao Ye, Henry M. Sanchez, Margot Hultz et al.     The highly specialized endothelial cells in brain capillaries are a key component of the blood-brain barrier, forming a network of tight junctions that almost completely block …             8-oxoguanine causes spontaneous de novo germline mutations in mice ▶     Mizuki Ohno, Kunihiko Sakumi, Ryutaro Fukumura et al.     Spontaneous germline mutations generate genetic diversity in populations of sexually reproductive organisms, and are thus regarded as a driving force of evolution. However, the …             Rewiring yeast osmostress signalling through the MAPK network reveals essential and non-essential roles of Hog1 in osmoadaptation ▶     Roja Babazadeh, Takako Furukawa, Stefan Hohmann et al.     Mitogen-activated protein kinases (MAPKs) have a number of targets which they regulate at transcriptional and post-translational levels to mediate specific responses. The yeast …             Promotion of atherosclerosis by Helicobacter cinaedi infection that involves macrophage-driven proinflammatory responses ▶     Shahzada Khan, H. N. Ashiqur Rahman, Tatsuya Okamoto et al.     Helicobacter cinaedi is the most common enterohepatic Helicobacter species that causes bacteremia in humans, but its pathogenicity is unclear. Here, we investigated the possible …             JNK confers 5-fluorouracil resistance in p53-deficient and mutant p53-expressing colon cancer cells by inducing survival autophagy ▶     Xinbing Sui, Na Kong, Xian Wang et al.     Deficiency or mutation in the p53 tumor suppressor gene commonly occurs in human cancer and can contribute to disease progression and chemotherapy resistance. 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