The Pharmacogenomics Journal - Table of Contents alert Volume 14 Issue 2

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TABLE OF CONTENTS Volume 14, Issue 2 (April 2014) In this issue Review Original Articles Also new AOP Webinar: Got Diagnosed, Now What? Leveraging PGx for Truly Personalized Medicine Learn to address the challenge of screening patient genomes for actionable variants and access data that provides rich and structured supporting information for these associations, and how relevant variants can be discovered in a sample patient. PGMD™ is your resource for identifying all published genetic variants that have been shown to affect drug response in patients. Click here to watch the webinar. Sign up for e-alerts Recommend to your library Web feed Subscribe Advertisement Don't miss these latest hot articles from Molecular Psychiatry:   - Rewards of beauty: the opioid system mediates social motivation in humans   - Stress and glucocorticoids promote oligodendrogenesis in the adult hippocampus   - Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci      Review Top Gene expression analysis in RA: towards personalized medicine OPEN A N Burska, K Roget, M Blits, L Soto Gomez, F van de Loo, L D Hazelwood, C L Verweij, A Rowe, G N Goulielmos, L G M van Baarsen and F Ponchel Pharmacogenomics J 2014 14: 93-106; advance online publication, March 4, 2014; 10.1038/tpj.2013.48 Abstract | Full Text Original Articles Top Functional characterization of 32 CYP2C9 allelic variants Y Niinuma, T Saito, M Takahashi, C Tsukada, Mi Ito, N Hirasawa and M Hiratsuka Pharmacogenomics J 2014 14: 107-114; advance online publication, June 11, 2013; 10.1038/tpj.2013.22 Abstract | Full Text The role of the MTHFR 677C>T polymorphism in methotrexate-induced liver toxicity: a meta-analysis in patients with cancer M M Hagleitner, M J H Coenen, R Aplenc, A Patiño-Garcia, P Chiusolo, D Gemmati, M De Mattei, A Ongaro, M Krajinovic, P M Hoogerbrugge, S H H M Vermeulen and D M W M te Loo Pharmacogenomics J 2014 14: 115-119; advance online publication, May 7, 2013; 10.1038/tpj.2013.19 Abstract | Full Text Association of UGT1A1*28 polymorphisms with irinotecan-induced toxicities in colorectal cancer: a meta-analysis in Caucasians OPEN X Liu, D Cheng, Q Kuang, G Liu and W Xu Pharmacogenomics J 2014 14: 120-129; advance online publication, March 26, 2013; 10.1038/tpj.2013.10 Abstract | Full Text The cyclin D1 (CCND1) rs9344 G>A polymorphism predicts clinical outcome in colon cancer patients treated with adjuvant 5-FU-based chemotherapy G Absenger, L Benhaim, J Szkandera, W Zhang, D Yang, M J Labonte, M Pichler, M Stotz, H Samonigg, W Renner, A Gerger and H-J Lenz Pharmacogenomics J 2014 14: 130-134; advance online publication, April 9, 2013; 10.1038/tpj.2013.15 Abstract | Full Text Gender-specific profiling in SCN1A polymorphisms and time-to-recurrence in patients with stage II/III colorectal cancer treated with adjuvant 5-fluoruracil chemotherapy L Benhaim, A Gerger, P Bohanes, D Paez, T Wakatsuki, D Yang, M J LaBonte, Y Ning, R El-Khoueiry, F Loupakis, W Zhang, P Laurent-Puig and H J Lenz Pharmacogenomics J 2014 14: 135-141; advance online publication, June 11, 2013; 10.1038/tpj.2013.21 Abstract | Full Text Association of common gene variants in the WNT/β-catenin pathway with colon cancer recurrence D Páez, A Gerger, W Zhang, D Yang, M J Labonte, L Benhanim, M Kahn, F Lenz, C Lenz, Y Ning, T Wakatsuki, F Loupakis and H-J Lenz Pharmacogenomics J 2014 14: 142-150; advance online publication, July 2, 2013; 10.1038/tpj.2013.20 Abstract | Full Text Efavirenz-mediated induction of omeprazole metabolism is CYP2C19 genotype dependent V Michaud, Y Kreutz, T Skaar, E Ogburn, N Thong, D A Flockhart and Z Desta Pharmacogenomics J 2014 14: 151-159; advance online publication, April 30, 2013; 10.1038/tpj.2013.17 Abstract | Full Text Higher frequency of genetic variants conferring increased risk for ADRs for commonly used drugs treating cancer, AIDS and tuberculosis in persons of African descent F Aminkeng, C J D Ross, S R Rassekh, L R Brunham, J Sistonen, M-P Dube, M Ibrahim, T B Nyambo, S A Omar, A Froment, J-M Bodo, S Tishkoff, B C Carleton and M R Hayden The Canadian Pharmacogenomics Network for Drug Safety Consortium Pharmacogenomics J 2014 14: 160-170; advance online publication, April 16, 2013; 10.1038/tpj.2013.13 Abstract | Full Text Association of a complement receptor 1 gene variant with baseline erythrocyte sedimentation rate levels in patients starting anti-TNF therapy in a UK rheumatoid arthritis cohort: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate cohort OPEN BRAGGSS:  H Gaston, D Mulherin, T Price, T Sheeran, V Chalam, S Baskar, P Emery, A Morgan, M Buch, S Bingham, S O'Reilly, L Badcock, M Regan, T Ding, C Deighton, G Summers, N Raj, R Stevens, N Williams, J Isaacs, P Platt, D Walker, L Kay, B Griffiths, W-F Ng, P Peterson, A Lorenzi, H Foster, M Friswell, B Thompson, M Lee, I Griffiths, A Hassell, P Dawes, C Dowson, S Kamath, J Packham, M Shadforth, Ann Brownfield, R Williams, C Mukhtyar, B Harrison, N Snowden, S Naz, J Ledingham, R Hull, F McCrae, A Thomas, S Young Min, R Shaban, E Wong, C Kelly, C Heycock, J Hamilton, V Saravanan, G Wilson, D Bax, L Dunkley, M Akil, R Tattersall, R Kilding, S Till, J Boulton, T Tait, M Bukhari, J Halsey, L Ottewell, C Buckley, D Situnayake, D Carruthers, K Grindulis, F Khatack, S Elamanchi, K Raza, A Filer, R Jubb, R Abernathy, M Plant, S Pathare, F Clarke, S Tuck, J Fordham, A Paul, M Bridges, A Hakim, D O'Reilly, V Rajagopal, S Bhagat, C Edwards, P Prouse, R Moitra, D Shawe, A Bamji, P Klimiuk, A Bowden, W Mitchell, I Bruce, A Barton, R Gorodkin, P Ho, K Hyrich, W Dixon, A Rai, G Kitas, N Erb, R Klocke, K Douglas, A Pace, R Sandhu, A Whallett, F Birrell, M Allen, K Chaudhuri, C Chattopadhyay, J McHale, A Jones, A Gupta, I Pande, I Gaywood, P Lanyon, P Courtney, M Doherty, H Chinoy, T O'Neill, A Herrick, A Jones, R Cooper, R Bucknall, C Marguerie, S Rigby, N Dunn, S Green, A Al-Ansari, S Webber, N Hopkinson, C Dunne, B Quilty, B Szebenyi, M Green, M Quinn, A Isdale, A Brown, B Saleem, A Samanta, P Sheldon, W Hassan, J Francis, A Kinder, R Neame, A Moorthy, W Al-Allaf, A Taggart, K Fairburn, F McKenna, M Green, A Gough, C Lawson, M Piper, E Korendowych, T Jenkinson, R Sengupta, A Bhalla, N McHugh, Debbie Bond, R Luqmani, B Bowness, P Wordsworth, J David, W Smith, D Mewar, E Tunn, K Nelson, T Kennedy, J Nixon, A Woolf, M Davis, D Hutchinson, A Endean, D Coady, D Wright, C Morley, G Raftery, C Bracewell, L Kidd, I Abbas, C Filer, G Kallarackal, J Bluett, I Ibrahim, D Plant, K L Hyrich, A W Morgan, A G Wilson, J D Isaacs and A Barton Pharmacogenomics J 2014 14: 171-175; advance online publication, July 16, 2013; 10.1038/tpj.2013.26 Abstract | Full Text Influence of CYP2D6 and CYP2C19 gene variants on antidepressant response in obsessive-compulsive disorder E J Brandl, A K Tiwari, X Zhou, J Deluce, J L Kennedy, D J Müller and M A Richter Pharmacogenomics J 2014 14: 176-181; advance online publication, April 2, 2013; 10.1038/tpj.2013.12 Abstract | Full Text Gene-expression differences in peripheral blood between lithium responders and non-responders in the Lithium Treatment-Moderate dose Use Study (LiTMUS) R D Beech, J J Leffert, A Lin, L G Sylvia, S Umlauf, S Mane, H Zhao, C Bowden, J R Calabrese, E S Friedman, T A Ketter, D V Iosifescu, N A Reilly-Harrington, M Ostacher, M E Thase and A Nierenberg Pharmacogenomics J 2014 14: 182-191; advance online publication, May 14, 2013; 10.1038/tpj.2013.16 Abstract | Full Text HIBAG—HLA genotype imputation with attribute bagging OPEN X Zheng, J Shen, C Cox, J C Wakefield, M G Ehm, M R Nelson and B S Weir Pharmacogenomics J 2014 14: 192-200; advance online publication, May 28, 2013; 10.1038/tpj.2013.18 Abstract | Full Text Advertisement Nature Middle East is your free news portal covering the latest research and scientific breakthroughs in the Arabic-speaking Middle East. 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