Journal of Investigative Dermatology - Table of Contents alert Volume 134 Issue 2

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TABLE OF CONTENTS Volume 134, Issue 2 (February 2014) In this issue Editorial Research Techniques Made Simple JID VisualDx Quiz Commentaries Review Article Original Articles Letters to the Editor Errata Corrigendum Also new AOP Sign up for e-alerts Recommend to your library Web feed Subscribe Advertisement Access these highly downloaded articles from JID FREE online.  Autoimmune Destruction of Skin Melanocytes by Perilesional T Cells from Vitiligo Patients   TSLP Produced by Keratinocytes Promotes Allergen Sensitization through Skin and Thereby Triggers Atopic March in Mice  Editorial Top Clinician Scientists and PhDs: The Need to Connect Basic Research to Translational Medicine—A Personal Experience Carien M Niessen and Thomas Krieg Associate Editor J Invest Dermatol 2014 134: 295-298; 10.1038/jid.2013.466 Full Text | PDF Clinical Snippets J Invest Dermatol 2014 134: 299; 10.1038/jid.2013.518 Full Text | PDF BJD Editor's Choice J Invest Dermatol 2014 134: 300; 10.1038/jid.2013.519 Full Text | PDF Editors' Picks J Invest Dermatol 2014 134: 301; 10.1038/jid.2013.520 Full Text | PDF Research Techniques Made Simple Top Antibody Phage Display: Technique and Applications Christoph M Hammers and John R Stanley J Invest Dermatol 2014 134: e17; 10.1038/jid.2013.521 Full Text | PDF JID VisualDx Quiz Top JID VisualDx Quiz: January 2014 Joshua R Freedman and Robert S Kirsner J Invest Dermatol 2014 134: e13; 10.1038/jid.2013.522 Full Text | PDF Commentaries Top Commentary on ‘‘Dynamic Analysis of Histamine-Mediated Attenuation of Acetylcholine-Induced Sweating via GSK3β Activation’’ Torsten Zuberbier and Margitta Worm J Invest Dermatol 2014 134: 302-303; 10.1038/jid.2013.436 Abstract | Full Text | PDF Alternative Models of Comorbidity: A Framework for the Interpretation of Epidemiological Association Studies Jochen Schmitt and Stephan Weidinger J Invest Dermatol 2014 134: 303-307; 10.1038/jid.2013.527 Abstract | Full Text | PDF IL-17: A Key Player in the P. acnes Inflammatory Cascade? Diane M Thiboutot, Alison M Layton and E Anne Eady J Invest Dermatol 2014 134: 307-310; 10.1038/jid.2013.400 Abstract | Full Text | PDF New Insights into Acne Pathogenesis: Propionibacterium Acnes Activates the Inflammasome Emmanuel Contassot and Lars E French J Invest Dermatol 2014 134: 310-313; 10.1038/jid.2013.505 Abstract | Full Text | PDF Crossing Barriers; Restoring Barriers? Filaggrin Protein Replacement Takes a Bow Alan D Irvine J Invest Dermatol 2014 134: 313-314; 10.1038/jid.2013.506 Abstract | Full Text | PDF On the TRAIL to Overcome BRAF-Inhibitor Resistance Peter Geserick, Meenhard Herlyn and Martin Leverkus J Invest Dermatol 2014 134: 315-318; 10.1038/jid.2013.348 Abstract | Full Text | PDF Review Article Top MELANOCYTES/MELANOMA Resistance to RAF Inhibitors Revisited Edward Hartsough, Yongping Shao and Andrew E Aplin J Invest Dermatol 2014 134: 319-325; advance online publication, October 10, 2013; 10.1038/jid.2013.358 Abstract | Full Text | PDF Original Articles Top APPENDAGES Dynamic Analysis of Histamine-Mediated Attenuation of Acetylcholine-Induced Sweating via GSK3β Activation Saki Matsui, Hiroyuki Murota, Aya Takahashi, Lingli Yang, Jeong-Beom Lee, Kouta Omiya, Masato Ohmi, Junichi Kikuta, Masaru Ishii and Ichiro Katayama J Invest Dermatol 2014 134: 326-334; advance online publication, July 30, 2013; 10.1038/jid.2013.323 Abstract | Full Text | PDF CELL BIOLOGY Highly Rapid and Efficient Conversion of Human Fibroblasts to Keratinocyte-Like Cells Yifang Chen, Devendra S Mistry and George L Sen J Invest Dermatol 2014 134: 335-344; advance online publication, August 6, 2013; 10.1038/jid.2013.327 Abstract | Full Text | PDF CLINICAL RESEARCH Atopic Dermatitis and Disease Severity Are the Main Risk Factors for Food Sensitization in Exclusively Breastfed Infants Carsten Flohr, Michael Perkin, Kirsty Logan, Tom Marrs, Suzana Radulovic, Linda E Campbell, Stephanie F MacCallum, W H Irwin McLean and Gideon Lack J Invest Dermatol 2014 134: 345-350; advance online publication, July 18, 2013; 10.1038/jid.2013.298 Abstract | Full Text | PDF Responsiveness to Change and Interpretability of the Simplified Psoriasis Index Leena Chularojanamontri, Christopher E M Griffiths and Robert J G Chalmers J Invest Dermatol 2014 134: 351-358; advance online publication, July 29, 2013; 10.1038/jid.2013.318 Abstract | Full Text | PDF GENETICS Identification of a Missense Variant in LNPEP that Confers Psoriasis Risk Hui Cheng, Yang Li, Xian-Bo Zuo, Hua-Yang Tang, Xian-Fa Tang, Jin-Ping Gao, Yu-Jun Sheng, Xian-Yong Yin, Fu-Sheng Zhou, Chi Zhang, Gang Chen, Jun Zhu, Qian Pan, Bo Liang, Xiao-Dong Zheng, Pan Li, Yan-Tao Ding, Fang Cheng, Jing Luo, Rui-Xue Chang, Gong-Bu Pan, Xing Fan, Zai-Xing Wang, An-Ping Zhang, Jian-Jun Liu, Sen Yang, Liang-Dan Sun and Xue-Jun Zhang J Invest Dermatol 2014 134: 359-365; advance online publication, July 29, 2013; 10.1038/jid.2013.317 Abstract | Full Text | PDF IMMUNOLOGY/INFECTION Propionibacterium acnes Induces an IL-17 Response in Acne Vulgaris that Is Regulated by Vitamin A and Vitamin D George W Agak, Min Qin, Jennifer Nobe, Myung-Hwa Kim, Stephan R Krutzik, Grogan R Tristan, David Elashoff, Hermes J Garbán and Jenny Kim J Invest Dermatol 2014 134: 366-373; advance online publication, August 7, 2013; 10.1038/jid.2013.334 Abstract | Full Text | PDF The Pattern Recognition Receptor NOD2 Mediates Staphylococcus aureus–Induced IL-17C Expression in Keratinocytes Sarah A Roth, Maren Simanski, Franziska Rademacher, Lena Schröder and Jürgen Harder J Invest Dermatol 2014 134: 374-380; advance online publication, July 26, 2013; 10.1038/jid.2013.313 Abstract | Full Text | PDF Propionibacterium acnes Induces IL-1β Secretion via the NLRP3 Inflammasome in Human Monocytes Min Qin, Aslan Pirouz, Myung-Hwa Kim, Stephan R Krutzik, Hermes J Garbán and Jenny Kim J Invest Dermatol 2014 134: 381-388; advance online publication, July 24, 2013; 10.1038/jid.2013.309 Abstract | Full Text | PDF Potential Synergy between SNP and CpG-A or IL-1β in Regulating Transcriptional Activity of IL-20 Promoter Lanqi Wang, Kejia Li, Qiannan Xu, Xiaoying Chen, Feng Xue, Ruofei Shi and Jie Zheng J Invest Dermatol 2014 134: 389-395; advance online publication, July 26, 2013; 10.1038/jid.2013.314 Abstract | Full Text | PDF NKG2D Triggers Cytotoxicity in Murine Epidermal γδ T Cells via PI3K-Dependent, Syk/ZAP70-Independent Signaling Pathway Atsuko Ibusuki, Kazuhiro Kawai, Shigeru Yoshida, Youhei Uchida, Ayano Nitahara-Takeuchi, Kimiko Kuroki, Mizuho Kajikawa, Toyoyuki Ose, Katsumi Maenaka, Masanori Kasahara and Takuro Kanekura J Invest Dermatol 2014 134: 396-404; advance online publication, August 20, 2013; 10.1038/jid.2013.353 Abstract | Full Text | PDF KERATINOCYTES/EPIDERMIS Matriptase Regulates Proliferation and Early, but Not Terminal, Differentiation of Human Keratinocytes Ya-Wen Chen, Jehng-Kang Wang, Fen-Pai Chou, Bai-Yao Wu, Hui-Chung Hsiao, Han Chiu, Zhonghong Xu, Adrienne N.H. Baksh, Galen Shi, Malvika Kaul, Robert Barndt, Victoria K Shanmugam, Michael D Johnson and Chen-Yong Lin J Invest Dermatol 2014 134: 405-414; advance online publication, July 26, 2013; 10.1038/jid.2013.320 Abstract | Full Text | PDF c-Rel Downregulation Affects Cell Cycle Progression of Human Keratinocytes Verena N Lorenz, Michael P Schön and Cornelia S Seitz J Invest Dermatol 2014 134: 415-422; advance online publication, July 26, 2013; 10.1038/jid.2013.315 Abstract | Full Text | PDF Recombinant Filaggrin Is Internalized and Processed to Correct Filaggrin Deficiency Thomas E Stout, Trevor McFarland, John C Mitchell, Binoy Appukuttan and J Timothy Stout J Invest Dermatol 2014 134: 423-429; advance online publication, June 21, 2013; 10.1038/jid.2013.284 Abstract | Full Text | PDF MELANOCYTES/MELANOMA RAF Inhibition Overcomes Resistance to TRAIL-Induced Apoptosis in Melanoma Cells Anja Berger, Sandra-Annika Quast, Michael Plötz, Nicholas-Frederik Kuhn, Uwe Trefzer and Jürgen Eberle J Invest Dermatol 2014 134: 430-440; advance online publication, August 16, 2013; 10.1038/jid.2013.347 Abstract | Full Text | PDF Transcription Factor/microRNA Axis Blocks Melanoma Invasion Program by miR-211 Targeting NUAK1 Rachel E Bell, Mehdi Khaled, Dvir Netanely, Steffen Schubert, Tamar Golan, Amir Buxbaum, Maja M Janas, Benny Postolsky, Michael S Goldberg, Ron Shamir and Carmit Levy J Invest Dermatol 2014 134: 441-451; advance online publication, August 9, 2013; 10.1038/jid.2013.340 Abstract | Full Text | PDF Somatic Mutations in MAP3K5 Attenuate Its Proapoptotic Function in Melanoma through Increased Binding to Thioredoxin Todd D Prickett, Brad Zerlanko, Jared J Gartner, Stephen C J Parker, Ken Dutton-Regester, Jimmy C Lin, Jamie K Teer, Xiaomu Wei, Jiji Jiang, NISC Comparative Sequencing Program, Guo Chen, Michael A Davies, Jeffrey E Gershenwald, William Robinson, Steven Robinson, Nicholas K Hayward, Steven A Rosenberg, Elliott H Margulies and Yardena Samuels J Invest Dermatol 2014 134: 452-460; advance online publication, September 5, 2013; 10.1038/jid.2013.365 Abstract | Full Text | PDF MicroRNA-203 Regulates Melanosome Transport and Tyrosinase Expression in Melanoma Cells by Targeting Kinesin Superfamily Protein 5b Shunsuke Noguchi, Minami Kumazaki, Yuki Yasui, Takashi Mori, Nami Yamada and Yukihiro Akao J Invest Dermatol 2014 134: 461-469; advance online publication, July 22, 2013; 10.1038/jid.2013.310 Abstract | Full Text | PDF IL-18 Regulates Melanoma VLA-4 Integrin Activation through a Hierarchized Sequence of Inflammatory Factors María Valcárcel, Teresa Carrascal, Olatz Crende and Fernando Vidal-Vanaclocha J Invest Dermatol 2014 134: 470-480; advance online publication, August 12, 2013; 10.1038/jid.2013.342 Abstract | Full Text | PDF Association of Genetic Variants in CDK6 and XRCC1 with the Risk of Dysplastic Nevi in Melanoma-Prone Families Xueying Liang, Ruth M Pfeiffer, Wen-Qing Li, Myriam Brossard, Laura S Burke, William Wheeler, Donato Calista, Maria Concetta Fargnoli, Paola Ghiorzo, Ketty Peris, Giovanna Bianchi-Scarra, Valerie Chaudru, Diana Zelenika, Dennis Maeder, Laurie Burdette, Meredith Yeager, Stephen Chanock, Maria Teresa Landi, Florence Demenais, Margaret A Tucker, Alisa M Goldstein and Xiaohong R Yang J Invest Dermatol 2014 134: 481-487; advance online publication, July 26, 2013; 10.1038/jid.2013.316 Abstract | Full Text | PDF Oncogenic Activation of MEK/ERK Primes Melanoma Cells for Adaptation to Endoplasmic Reticulum Stress Amanda Croft, Kwang H Tay, Suzanah C Boyd, Su T Guo, Chen C Jiang, Fritz Lai, Hsin-Yi Tseng, Lei Jin, Helen Rizos, Peter Hersey and Xu D Zhang J Invest Dermatol 2014 134: 488-497; advance online publication, August 6, 2013; 10.1038/jid.2013.325 Abstract | Full Text | PDF TUMOR BIOLOGY Complement Factor H: A Biomarker for Progression of Cutaneous Squamous Cell Carcinoma Pilvi M Riihilä, Liisa M Nissinen, Risto Ala-aho, Markku Kallajoki, Reidar Grénman, Seppo Meri, Sirkku Peltonen, Juha Peltonen and Veli-Matti Kähäri J Invest Dermatol 2014 134: 498-506; advance online publication, August 12, 2013; 10.1038/jid.2013.346 Abstract | Full Text | PDF MicroRNA Expression Patterns Related to Merkel Cell Polyomavirus Infection in Human Merkel Cell CarcinomaJIDOPEN Hong Xie, Linkiat Lee, Stefano Caramuta, Anders Höög, Nanna Browaldh, Viveca Björnhagen, Catharina Larsson and Weng-Onn Lui J Invest Dermatol 2014 134: 507-517; advance online publication, August 20, 2013; 10.1038/jid.2013.355 Abstract | Full Text | PDF WOUND HEALING YAP and TAZ Regulate Skin Wound Healing Min-Jung Lee, Mi Ran Byun, Makoto Furutani-Seiki, Jeong-Ho Hong and Han-Sung Jung J Invest Dermatol 2014 134: 518-525; advance online publication, August 9, 2013; 10.1038/jid.2013.339 Abstract | Full Text | PDF TSG-6 Released from Intradermally Injected Mesenchymal Stem Cells Accelerates Wound Healing and Reduces Tissue Fibrosis in Murine Full-Thickness Skin Wounds Yu Qi, Dongsheng Jiang, Anca Sindrilaru, Agatha Stegemann, Susanne Schatz, Nicolai Treiber, Markus Rojewski, Hubert Schrezenmeier, Seppe Vander Beken, Meinhard Wlaschek, Markus Böhm, Andreas Seitz, Natalie Scholz, Lutz Dürselen, Jürgen Brinckmann, Anita Ignatius and Karin Scharffetter-Kochanek J Invest Dermatol 2014 134: 526-537; advance online publication, August 6, 2013; 10.1038/jid.2013.328 Abstract | Full Text | PDF Letters to the Editor Top Dissociated Human Dermal Papilla Cells Induce Hair Follicle Neogenesis in Grafted Dermal–Epidermal Composites Rajesh L Thangapazham, Peter Klover, Ji-an Wang, Ying Zheng, Amanda Devine, Shaowei Li, Leonard Sperling, George Cotsarelis and Thomas N Darling J Invest Dermatol 2014 134: 538-540; advance online publication, August 7, 2013; 10.1038/jid.2013.337 Full Text | PDF Mild Mitochondrial Uncoupling Prevents Premature Senescence in Human Dermal Fibroblasts Si Young Cho, Dae-Bang Seo, Wan Gi Kim and Sang-Jun Lee J Invest Dermatol 2014 134: 540-543; advance online publication, August 20, 2013; 10.1038/jid.2013.352 Full Text | PDF AKT1 Gene Mutation Levels Are Correlated with the Type of Dermatologic Lesions in Patients with Proteus Syndrome Marjorie J Lindhurst, Ji-an Wang, Hadley M Bloomhardt, Alison M Witkowski, Larry N Singh, David P Bick, Michael J Gambello, Cynthia M Powell, Chyi-Chia Richard Lee, Thomas N Darling and Leslie G Biesecker J Invest Dermatol 2014 134: 543-546; advance online publication, July 24, 2013; 10.1038/jid.2013.312 Full Text | PDF Histamine H4 Receptor Antagonists Ineffective against Itch and Skin Inflammation in Atopic Dermatitis Mouse Model Atsuko Kamo, Osamu Negi, Suhandy Tengara, Yayoi Kamata, Atsushi Noguchi, Hideoki Ogawa, Mitsutoshi Tominaga and Kenji Takamori J Invest Dermatol 2014 134: 546-548; advance online publication, August 20, 2013; 10.1038/jid.2013.351 Full Text | PDF The BRAF V600K Mutation Is More Frequent than the BRAF V600E Mutation in Melanoma In Situ of Lentigo Maligna Type Elke Stadelmeyer, Ellen Heitzer, Margit Resel, Lorenzo Cerroni, Peter Wolf and Nadia Dandachi J Invest Dermatol 2014 134: 548-550; advance online publication, August 9, 2013; 10.1038/jid.2013.338 Full Text | PDF Downregulation of Melanocyte-Specific Facultative Melanogenesis by 4-Hydroxy-3-Methoxycinnamaldehyde Acting as a cAMP Antagonist Eunmiri Roh, In-Yeong Jeong, Hyoeun Shin, Sukgil Song, Nam Doo Kim, Sang-Hun Jung, Jin Tae Hong, Seung Ho Lee, Sang-Bae Han and Youngsoo Kim J Invest Dermatol 2014 134: 551-553; advance online publication, August 7, 2013; 10.1038/jid.2013.341 Full Text | PDF A Somatic Mutation of the KEAP1 Gene in Malignant Melanoma Is Involved in Aberrant NRF2 Activation and an Increase in Intrinsic Drug Resistance Shinpei Miura, Masahiko Shibazaki, Shuya Kasai, Shinji Yasuhira, Ayano Watanabe, Tsuyoshi Inoue, Yuich Kageshita, Kanako Tsunoda, Kazuhiro Takahashi, Toshihide Akasaka, Tomoyuki Masuda and Chihaya Maesawa J Invest Dermatol 2014 134: 553-556; advance online publication, August 12, 2013; 10.1038/jid.2013.343 Full Text | PDF The New Aryl Hydrocarbon Receptor Antagonist E/Z-2-Benzylindene-5,6-Dimethoxy-3,3-Dimethylindan-1-One Protects against UVB-Induced Signal Transduction Julia Tigges, Thomas Haarmann-Stemmann, Christoph F A Vogel, Annemarie Grindel, Ulrike Hübenthal, Heidi Brenden, Susanne Grether-Beck, Gabriele Vielhaber, William Johncock, Jean Krutmann and Ellen Fritsche J Invest Dermatol 2014 134: 556-559; advance online publication, August 30, 2013; 10.1038/jid.2013.362 Full Text | PDF A Bio-Mimetic Approach to DNA Photoprotection Abbas Raza, Marna E Ericson, Jaime S Nugent, Christine D Dreis and Robert Vince J Invest Dermatol 2014 134: 559-562; advance online publication, August 12, 2013; Full Text | PDF Downregulation of SAMHD1 Expression Correlates with Promoter DNA Methylation in Sézary Syndrome Patients Suresh de Silva, Feifei Wang, Timothy S Hake, Pierluigi Porcu, Henry K Wong and Li Wu J Invest Dermatol 2014 134: 562-565; advance online publication, July 24, 2013; 10.1038/jid.2013.311 Full Text | PDF Slug Expression in Mouse Skin and Skin Tumors Is Not Regulated by p53 Carlos J Perez, Joyce E Rundhaug, David G Johnson, Tatiana M Oberyszyn, Kathleen L Tober and Donna F Kusewitt J Invest Dermatol 2014 134: 566-568; advance online publication, September 5, 2013; 10.1038/jid.2013.363 Full Text | PDF SLC24A5 Mutations Are Associated with Non-Syndromic Oculocutaneous Albinism Fanny Morice-Picard, Eulalie Lasseaux, Stéphane François, Delphine Simon, Caroline Rooryck, Eric Bieth, Estelle Colin, Dominique Bonneau, Hubert Journel, Sophie Walraedt, Bart P Leroy, Francoise Meire, Didier Lacombe and Benoit Arveiler J Invest Dermatol 2014 134: 568-571; advance online publication, August 28, 2013; 10.1038/jid.2013.360 Full Text | PDF Long-Term Survival of Type XVII Collagen Revertant Cells in an Animal Model of Revertant Cell Therapy Antoni Gostyński, Sara Llames, Marta García, María J Escamez, Lucía Martinez-Santamaria, Miranda Nijenhuis, Alvaro Meana, Hendri H Pas, Fernando Larcher, Anna M G Pasmooij, Marcel F Jonkman and Marcela Del Rio J Invest Dermatol 2014 134: 571-574; advance online publication, July 24, 2013; 10.1038/jid.2013.308 Full Text | PDF NKp46-Specific Expression on Skin-Resident CD4+ Lymphocytes in Mycosis Fungoides and Sézary Syndrome Pierre Schneider, Louis-François Plassa, Philippe Ratajczak, Christophe Leboeuf, Laurence Verneuil, Maxime Battistella, Armand Bensussan, Martine Bagot and Anne Janin J Invest Dermatol 2014 134: 574-578; advance online publication, July 30, 2013; 10.1038/jid.2013.321 Full Text | PDF Generalized Pustular Psoriasis Triggered by Amoxicillin in Monozygotic Twins with Compound Heterozygous IL36RN Mutations: Comment on the Article by Navarini et al. Kazumitsu Sugiura, Yukiko Shoda and Masashi Akiyama J Invest Dermatol 2014 134: 578-579; advance online publication, August 20, 2013; 10.1038/jid.2013.354 Full Text | PDF Generalized Pustular Eruptions: Time to Adapt the Disease Taxonomy to the Genetic Architecture? Alexander A Navarini, Laurence Valeyrie-Allanore, Niovi Setta-Kaffetzi, Jonathan N Barker, Francesca Capon, Daniel Creamer, Jean-Claude Roujeau, Peggy Sekula, Michael A Simpson, Richard C Trembath, Maja Mockenhaupt and Catherine H Smith J Invest Dermatol 2014 134: 580-581; advance online publication, August 16, 2013; 10.1038/jid.2013.349 Full Text | PDF Skin Is Not the Largest Organ Richard D Sontheimer J Invest Dermatol 2014 134: 581-582; advance online publication, August 7, 2013; 10.1038/jid.2013.335 Full Text | PDF Reply to Sontheimer Lowell A Goldsmith J Invest Dermatol 2014 134: 582; advance online publication, August 7, 2013; 10.1038/jid.2013.336 Full Text | PDF JID VisualDx Quiz: April 2013 Adriane Vega and Robert S. Kirsner J Invest Dermatol 2014 134: 583; advance online publication, November 14, 2013; 10.1038/jid.2013.431 Full Text | PDF Errata Top Toll-Like Receptor 4 Has an Essential Role in Early Skin Wound Healing Lin Chen, Shujuan Guo, Matthew J Ranzer and Luisa A DiPietro J Invest Dermatol 2014 134: 583; advance online publication, December 19, 2013; 10.1038/jid.2013.529 Full Text | PDF Corrigenda Top Identification of Multiple Complex Rearrangements Associated with Deletions in the 6q23-27 Region in Sézary Syndrome Katarzyna Iżykowska, Mariola Zawada, Karina Nowicka, Piotr Grabarczyk, Floriane C M Braun, Martin Delin, Markus Möbs, Marc Beyer, Wolfram Sterry, Christian A Schmidt and Grzegorz K Przybylski J Invest Dermatol 2014 134: 583; advance online publication, November 14, 2013; 10.1038/jid.2013.435 Full Text | PDF Advertisement Discover a world of scientific events.  The 2014 Natureevents Directory is packed with valuable information covering a complete range of scientific events, conferences and courses from around the world. 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