Cell Death and Differentiation - Table of Contents alert Volume 21 Issue 1

Special Issue on Molecular Mechanisms on Immunogenic Cell Death Successful anticancer chemotherapies and radiotherapeutic regimes do not only kill tumor cells but also induce an immune response against tumor antigens. Indeed, it appears that one of the hallmarks of cancer is the escape from immunosurveillance. Hence, the reinstatement of lost immunosurveillance constitutes one particularly promising therapeutic option. One strategy to elicit anticancer immune responses consists in the induction of ‘immunogenic cell death’ (ICD), which is a modality of cell death that is accompanied by the emission of danger signals capable of attracting innate immune effectors and stimulating the uptake and presentation of tumor antigens by dendritic cells. This issue of Cell Death and Differentiation deals with the molecular pathways involved in ICD, either within dying tumor cells or in the dialogue between dying cells and the immune system. This up-to-date compendium of reviews, commentaries and original articles treating a rapidly expanding field is a must read for cell biologists, oncologists and immunologists. TABLE OF CONTENTS Volume 21, Issue 1 (January 2014) In this issue Editorials Reviews Original Papers Also new AOP Sign up for e-alerts Recommend to your library Web feed Subscribe Editorials Top Killing cancer cells, twice with one shot M E Bianchi Cell Death Differ 2014 21: 1-2; 10.1038/cdd.2013.147 Full Text | PDF Dying from within: granzyme B converts entosis to emperitosis G S Salvesen Cell Death Differ 2014 21: 3-4; 10.1038/cdd.2013.157 Full Text Review Top Molecular mechanisms of natural killer cell activation in response to cellular stress C J Chan, M J Smyth and L Martinet Cell Death Differ 2014 21: 5-14; advance online publication, April 12, 2013; 10.1038/cdd.2013.26 Abstract | Full Text Immune-based mechanisms of cytotoxic chemotherapy: implications for the design of novel and rationale-based combined treatments against cancer L Bracci, G Schiavoni, A Sistigu and F Belardelli Cell Death Differ 2014 21: 15-25; advance online publication, June 21, 2013; 10.1038/cdd.2013.67 Abstract | Full Text Danger signalling during cancer cell death: origins, plasticity and regulation A D Garg, S Martin, J Golab and P Agostinis Cell Death Differ 2014 21: 26-38; advance online publication, May 17, 2013; 10.1038/cdd.2013.48 Abstract | Full Text Multimodal immunogenic cancer cell death as a consequence of anticancer cytotoxic treatments H Inoue and K Tani Cell Death Differ 2014 21: 39-49; advance online publication, July 5, 2013; 10.1038/cdd.2013.84 Abstract | Full Text Original Papers Top Contribution of humoral immune responses to the antitumor effects mediated by anthracyclines D Hannani, C Locher, T Yamazaki, V Colin-Minard, M Vetizou, L Aymeric, S Viaud, D Sanchez, M J Smyth, P Bruhns, G Kroemer and L Zitvogel Cell Death Differ 2014 21: 50-58; advance online publication, June 7, 2013; 10.1038/cdd.2013.60 Abstract | Full Text Immunogenic calreticulin exposure occurs through a phylogenetically conserved stress pathway involving the chemokine CXCL8 A Q Sukkurwala, I Martins, Y Wang, F Schlemmer, C Ruckenstuhl, M Durchschlag, M Michaud, L Senovilla, A Sistigu, Y Ma, E Vacchelli, E Sulpice, X Gidrol, L Zitvogel, F Madeo, L Galluzzi, O Kepp and G Kroemer Cell Death Differ 2014 21: 59-68; advance online publication, June 21, 2013; 10.1038/cdd.2013.73 Abstract | Full Text Defective immunogenic cell death of HMGB1-deficient tumors: compensatory therapy with TLR4 agonists T Yamazaki, D Hannani, V Poirier-Colame, S Ladoire, C Locher, A Sistigu, N Prada, S Adjemian, J PP Catani, M Freudenberg, C Galanos, F André, G Kroemer and L Zitvogel Cell Death Differ 2014 21: 69-78; advance online publication, June 28, 2013; 10.1038/cdd.2013.72 Abstract | Full Text Molecular mechanisms of ATP secretion during immunogenic cell death I Martins, Y Wang, M Michaud, Y Ma, A Q Sukkurwala, S Shen, O Kepp, D Métivier, L Galluzzi, J-L Perfettini, L Zitvogel and G Kroemer Cell Death Differ 2014 21: 79-91; advance online publication, July 12, 2013; 10.1038/cdd.2013.75 Abstract | Full Text Autophagy inhibition radiosensitizes in vitro, yet reduces radioresponses in vivo due to deficient immunogenic signalling OPEN A Ko, A Kanehisa, I Martins, L Senovilla, C Chargari, D Dugue, G Mariño, O Kepp, M Michaud, J-L Perfettini, G Kroemer and E Deutsch Cell Death Differ 2014 21: 92-99; advance online publication, September 13, 2013; 10.1038/cdd.2013.124 Abstract | Full Text The role, mechanism and potentially therapeutic application of microRNA-29 family in acute myeloid leukemia J-N Gong, J Yu, H-S Lin, X-H Zhang, X-L Yin, Z Xiao, F Wang, X-S Wang, R Su, C Shen, H-L Zhao, Y-N Ma and J-W Zhang Cell Death Differ 2014 21: 100-112; advance online publication, September 27, 2013; 10.1038/cdd.2013.133 Abstract | Full Text Proline oxidase–adipose triglyceride lipase pathway restrains adipose cell death and tissue inflammation D Lettieri Barbato, K Aquilano, S Baldelli, S M Cannata, S Bernardini, G Rotilio and M R Ciriolo Cell Death Differ 2014 21: 113-123; advance online publication, October 4, 2013; 10.1038/cdd.2013.137 Abstract | Full Text Metabolic regulation of cancer cell side population by glucose through activation of the Akt pathway P-P Liu, J Liao, Z-J Tang, W-J Wu, J Yang, Z-L Zeng, Y Hu, P Wang, H-Q Ju, R-H Xu and P Huang Cell Death Differ 2014 21: 124-135; advance online publication, October 4, 2013; 10.1038/cdd.2013.131 Abstract | Full Text A multifunctional protein EWS regulates the expression of Drosha and microRNAs K Y Kim, Y J Hwang, M-K Jung, J Choe, Y Kim, S Kim, C-J Lee, H Ahn, J Lee, N W Kowall, Y K Kim, J-I Kim, S B Lee and H Ryu Cell Death Differ 2014 21: 136-145; advance online publication, November 1, 2013; 10.1038/cdd.2013.144 Abstract | Full Text p34 is a novel regulator of the oncogenic behavior of NEDD4-1 and PTEN S-W Hong, J-H Moon, J-S Kim, J-S Shin, K-A Jung, W-K Lee, S-Y Jeong, J J Hwang, S-J Lee, Y-A Suh, I Kim, K-Y Nam, S Han, J E Kim, K-p Kim, Y S Hong, J-L Lee, W-J Lee, E K Choi, J S Lee, D-H Jin and T W Kim Cell Death Differ 2014 21: 146-160; advance online publication, October 18, 2013; 10.1038/cdd.2013.141 Abstract | Full Text Remodelling of a polypyrimidine tract-binding protein complex during apoptosis activates cellular IRESs OPEN H A King, L C Cobbold, X Pichon, T Pöyry, L A Wilson, H Booden, R Jukes-Jones, K Cain, K S Lilley, M Bushell and A E Willis Cell Death Differ 2014 21: 161-171; advance online publication, October 18, 2013; 10.1038/cdd.2013.135 Abstract | Full Text Caspase-cleaved arrestin-2 and BID cooperatively facilitate cytochrome C release and cell death S Kook, X Zhan, W M Cleghorn, J L Benovic, V V Gurevich and E V Gurevich Cell Death Differ 2014 21: 172-184; advance online publication, October 18, 2013; 10.1038/cdd.2013.143 Abstract | Full Text Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here. Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. For event advertising opportunities across the Nature Publishing Group portfolio please contact natureevents@nature.com More Nature Events Please note that you need to be a subscriber or site-licence holder to enjoy full-text access to Cell Death & Differentiation. In order to do so, please purchase a subscription. You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/nams/svc/myaccount (You will need to log in to be recognised as a nature.com registrant). For further technical assistance, please contact our registration department. For print subscription enquiries, please contact our subscription department. For other enquiries, please contact our customer feedback department. Nature Publishing Group | 75 Varick Street, 9th Floor | New York | NY 10013-1917 | USA Nature Publishing Group's worldwide offices: London - Paris - Munich - New Delhi - Tokyo - Melbourne San Diego - San Francisco - Washington - New York - Boston Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at Brunel Road, Houndmills, Basingstoke, Hampshire RG21 6XS. © 2013 Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.