Nature Communications - 13 November 2013

Weekly Content Alert 13 November 2013  Featured image: Zhang et al. provide evidence for early cattle management in North-Eastern China. Latest content: Articles Corrigendum Advertisement Just one of many high-quality articles from Frontiers in Plant Science: Root traits contributing to plant productivity under drought (open access) In this review, Louise Comas and colleagues discuss how a better understanding of root functional traits and how traits are related to whole plant strategies to increase crop productivity under different drought conditions is needed.  Journal homepage Recommend to library Web feed   Advertisement nature.com webcasts Macmillan Science Communication presents a custom webcast on: Investigation of chromosomal microarray analysis as the successor to prenatal karyotyping  Listen on demand, to this free webcast  Sponsored by:       Latest Articles View all Articles     Chondroitin sulphate N-acetylgalactosaminyl-transferase-1 inhibits recovery from neural injury OPEN Kosei Takeuchi, Nozomu Yoshioka, Susumu Higa Onaga, Yumi Watanabe, Shinji Miyata, Yoshino Wada, Chika Kudo, Masayasu Okada, Kentaro Ohko, Kanako Oda, Toshiya Sato, Minesuke Yokoyama, Natsuki Matsushita, Masaya Nakamura, Hideyuki Okano, Kenji Sakimura, Hitoshi Kawano, Hiroshi Kitagawa and Michihiro Igarashi The glycosaminoglycan chondroitin sulphate inhibits axon growth. Here, the authors show that mice deficient in chondroitin sulphate biosynthesis have increased levels of heparan sulphate, which is more efficient than chondroitinase in supporting recovery from spinal cord injury. 12 November 2013 | doi: 10.1038/ncomms3740 Biological Sciences  Medical research  Neuroscience  Stargazin regulates AMPA receptor trafficking through adaptor protein complexes during long-term depression Shinji Matsuda, Wataru Kakegawa, Timotheus Budisantoso, Toshihiro Nomura, Kazuhisa Kohda and Michisuke Yuzaki Long-term depression of synapses is mediated by the endocytosis of AMPA receptors. Matsuda et al. show that stargazin mediates both AMPA receptor internalization and subsequent endosomal sorting through sequential interactions with two different endocytic adapters. 12 November 2013 | doi: 10.1038/ncomms3759 Biological Sciences  Neuroscience  A cholinergic trigger drives learning-induced plasticity at hippocampal synapses OPEN Dai Mitsushima, Akane Sano and Takuya Takahashi Cholinergic signalling modulates learning and memory; however, its influence on learning-induced synaptic plasticity is less clear. Mitsushima et al. show that acetylcholine simultaneously strengthens both excitatory and inhibitory synapses onto CA1 pyramidal neurons following an inhibitory avoidance task. 12 November 2013 | doi: 10.1038/ncomms3760 Biological Sciences  Neuroscience  Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci Yan Zhang, Lin Fu, Xiaolong Qi, Zhenyi Zhang, Yuanxin Xia, Jianhang Jia, Jin Jiang, Yun Zhao and Geng Wu Suppressor of Fused (Sufu) controls the nucleocytoplasmic distribution of Gli transcription factors in response to Hedgehog signalling. Zhang et al. report crystal structures of the Sufu/Gli complex, and show that Sufu transitions from an open to a closed form in response to Gli binding. 12 November 2013 | doi: 10.1038/ncomms3608 Biological Sciences  Cell biology  Molecular biology  X-ray micro-beam characterization of lattice rotations and distortions due to an individual dislocation Felix Hofmann, Brian Abbey, Wenjun Liu, Ruqing Xu, Brian F. Usher, Eugeniu Balaur and Yuzi Liu Dislocations are materials defects that have a major influence on structural and functional properties. Here, Hofmann et al. quantify the strain field due to an individual dislocation using X-ray micro-beam Laue diffraction, validating textbook elasticity theories. 12 November 2013 | doi: 10.1038/ncomms3774 Physical Sciences  Materials science  Nanotechnology  An on-chip coupled resonator optical waveguide single-photon buffer OPEN Hiroki Takesue, Nobuyuki Matsuda, Eiichi Kuramochi, William J. Munro and Masaya Notomi Photonic circuits are a promising route to developing scalable quantum technologies, if all the necessary components can be built. Using coupled resonator optical waveguides, Takesue et al. present an on-chip single-photon buffer that can delay one photon from a pair for 150 ps while preserving entanglement. 12 November 2013 | doi: 10.1038/ncomms3725 Physical Sciences  Applied physics  Optical physics  Sodium and potassium competition in potassium-selective and non-selective channels OPEN David B. Sauer, Weizhong Zeng, John Canty, Yeeling Lam and Youxing Jiang K+ channels are selective for K+ despite the fact that Na+ can bind and conduct through the selectivity filter. Sauer et al. show that a K+-selective NaK2K channel has two high-affinity K+-binding sites, whereas a non-selective NaK2CNG channel has one, and propose a double-barrier mechanism for ion selectivity. 12 November 2013 | doi: 10.1038/ncomms3721 Biological Sciences  Biochemistry  Biophysics  Stratonovich-to-Itô transition in noisy systems with multiplicative feedback Giuseppe Pesce, Austin McDaniel, Scott Hottovy, Jan Wehr and Giovanni Volpe The noise in a stochastic differential equation can be interpreted by Itô or by Stratonovich calculus, and which one to use has been a subject of discussion in statistical physics. Pesce et al. show that the underlying dynamics induce a shift from Stratonovic to Itô calculus in a noisy electrical circuit. 12 November 2013 | doi: 10.1038/ncomms3733 Physical Sciences  Applied physics  Theoretical physics  Soluble forms of polyQ-expanded huntingtin rather than large aggregates cause endoplasmic reticulum stress Julia Leitman, F. Ulrich Hartl and Gerardo Z. Lederkremer Large insoluble aggregates of huntingtin are believed to contribute to the onset of Huntington's disease, partly by interfering with endoplasmic reticulum-associated protein degradation. Leitman et al. show that huntingtin interferes with protein degradation before it forms insoluble aggregates. 12 November 2013 | doi: 10.1038/ncomms3753 Biological Sciences  Cell biology  Neuroscience  Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase Chunfeng Zhu, Wenying Gao, Ke Zhao, Xiaohong Qin, Yinjie Zhang, Xin Peng, Lei Zhang, Yuhui Dong, Wenyan Zhang, Peng Li, Wei Wei, Yong Gong and Xiao-Fang Yu SAMHD1 is a dNTP hydrolase that has been shown to act as a restriction factor against retroviruses such as HIV, and also regulates the retrotransposition of LINE-1 elements. Here, the authors reveal the structural basis for dGTP-dependent tetramerization and allosteric activation of the enzyme. 12 November 2013 | doi: 10.1038/ncomms3722 Biological Sciences  Molecular biology  Virology  Equilibrium selectivity alone does not create K+-selective ion conduction in K+ channels Shian Liu and Steve W. Lockless The preference of potassium channels to bind K+ ions over Na+ ions at equilibrium has been proposed to determine their exclusive K+ conductance. Liu and Lockless show that a related, non-selective cation channel also binds only K+ ions at equilibrium, suggesting that this property alone does not determine selectivity. 12 November 2013 | doi: 10.1038/ncomms3746 Biological Sciences  Biochemistry  Biophysics  Efficient separation of the orbital angular momentum eigenstates of light Mohammad Mirhosseini, Mehul Malik, Zhimin Shi and Robert W. Boyd The orbital angular momentum of photons has the potential to dramatically increase data rates and enhance security in quantum optical communications. Here, Mirhosseini et al. demonstrate a scheme that is able to separate photons with different orbital angular momentum with 92% efficiency. 12 November 2013 | doi: 10.1038/ncomms3781 Physical Sciences  Optical physics  Hydrogen-atom-mediated electrochemistry Jin-Young Lee, Jae Gyeong Lee, Seok-Ha Lee, Minjee Seo, Lilin Piao, Je Hyun Bae, Sung Yul Lim, Young June Park and Taek Dong Chung Electrochemistry on dielectric surfaces seems counterintuitive. Lee et al. report a system consisting of a silicon electrode with a silicon oxide thin film and an aqueous electrolyte, in which protons can migrate from the solution through the oxide layer, thereby facilitating electrochemical reactions. 12 November 2013 | doi: 10.1038/ncomms3766 Chemical Sciences  Analytical chemistry  Catalysis  Materials science  Efficient organometal trihalide perovskite planar-heterojunction solar cells on flexible polymer substrates Pablo Docampo, James M. Ball, Mariam Darwich, Giles E. Eperon and Henry J. Snaith Low-cost, flexible solar cells offer new possibilities to harvest solar energy, for example on curved or movable surfaces. Here, Docampo and colleagues demonstrate the fabrication of efficient organometallic perovskite heterojunction solar cells on flexible substrates. 12 November 2013 | doi: 10.1038/ncomms3761 Physical Sciences  Materials science  Optical physics  The mechanism of caesium intercalation of graphene M. Petrović, I. Šrut Rakić, S. Runte, C. Busse, J. T. Sadowski, P. Lazić, I. Pletikosić, Z.-H. Pan, M. Milun, P. Pervan, N. Atodiresei, R. Brako, D. Šokčević, T. Valla, T. Michely and M. Kralj The intercalation of graphene can result in many attractive functional properties. Here, the authors study the mechanism of caesium intercalation of graphene, finding that it nucleates at wrinkles on the graphene surface and is influenced by van der Waals interactions. 11 November 2013 | doi: 10.1038/ncomms3772 Physical Sciences  Materials science  Nanotechnology  Atomically precise edge chlorination of nanographenes and its application in graphene nanoribbons OPEN Yuan-Zhi Tan, Bo Yang, Khaled Parvez, Akimitsu Narita, Silvio Osella, David Beljonne, Xinliang Feng and Klaus Müllen Chemical functionalization of graphene is a useful method for modulating its properties, although this is limited by a lack of control and resulting in poorly defined structures. Here, the authors report the atomically precise chlorination of nanographenes and apply the methods to graphene nanoribbons. 11 November 2013 | doi: 10.1038/ncomms3646 Chemical Sciences  Materials science  Organic chemistry  Efficient and tunable white-light emission of metal–organic frameworks by iridium-complex encapsulation OPEN Chun-Yi Sun, Xin-Long Wang, Xiao Zhang, Chao Qin, Peng Li, Zhong-Min Su, Dong-Xia Zhu, Guo-Gang Shan, Kui-Zhan Shao, Han Wu and Jing Li Although many metal–organic frameworks are luminescent, few are capable of white-light emission. Here, the authors incorporate a yellow-emitting guest molecule into the cavities of a blue-emitting metal–organic framework, and tune the composition to emit white light with relatively high quantum yield. 11 November 2013 | doi: 10.1038/ncomms3717 Chemical Sciences  Inorganic chemistry  Adaptive response to sociality and ecology drives the diversification of facial colour patterns in catarrhines Sharlene E. Santana, Jessica Lynch Alfaro, Andrew Noonan and Michael E. Alfaro Animal colouration is the product of competing selection pressures. Here, the authors analyse the diversity of facial colouration in Old World monkeys and apes, and find that colour patterns are linked to social factors, whereas the different levels of facial pigmentation arise as a result of ecological pressures. 11 November 2013 | doi: 10.1038/ncomms3765 Biological Sciences  Ecology  Evolution  Zoology  A Nodal-independent and tissue-intrinsic mechanism controls heart-looping chirality Emily S. Noël, Manon Verhoeven, Anne Karine Lagendijk, Federico Tessadori, Kelly Smith, Suma Choorapoikayil, Jeroen den Hertog and Jeroen Bakkers Nodal signalling has been implicated in the asymmetric positioning of various organs. Here, Noël et al. show that the asymmetry of the embryonic zebrafish heart is also established in the absence of Nodal signalling, suggesting a Nodal-independent mechanism that relies on actomyosin activity. 11 November 2013 | doi: 10.1038/ncomms3754 Biological Sciences  Cell biology  Developmental biology  Mutually synchronized bottom-up multi-nanocontact spin–torque oscillators S. Sani, J. Persson, S.M. Mohseni, Ye Pogoryelov, P.K. Muduli, A. Eklund, G. Malm, M. Käll, A. Dmitriev and J. Åkerman Spin–torque oscillators have potential as nanosized microwave signal generators, but presently they are limited by their small output power. Here, the authors develop a cheap lithographic method to fabricate spin–torque oscillators, which can be mutually synchronized to overcome the output-power limitation. 08 November 2013 | doi: 10.1038/ncomms3731 Physical Sciences  Applied physics  Condensed matter  Nanotechnology  RNA editing regulates transposon-mediated heterochromatic gene silencing Yiannis A. Savva, James E. C. Jepson, Yao-Jen Chang, Rachel Whitaker, Brian C. Jones, Georges St Laurent, Michael R. Tackett, Philipp Kapranov, Nan Jiang, Guyu Du, Stephen L. Helfand and Robert A. Reenan The Hoppel transposable element mediates heterochromatin formation in Drosophila. Here, Savva et al. report that the RNA-editing enzyme, ADAR, edits a long double-stranded RNA generated by the Hoppel transposon, thereby regulating heterochromatin formation and gene expression. 08 November 2013 | doi: 10.1038/ncomms3745 Biological Sciences  Molecular biology  Enhanced spin-triplet superconductivity near dislocations in Sr2RuO4 Y. A. Ying, N. E. Staley, Y. Xin, K. Sun, X. Cai, D. Fobes, T. J. Liu, Z. Q. Mao and Y. Liu Strontium ruthenate is an odd-parity superconductor that could support Majorana fermions. Ying et al. report that the critical temperature doubles near lattice dislocations in this material compared with its bulk, arising from effects that could be found in other unconventional superconductors. 08 November 2013 | doi: 10.1038/ncomms3596 Physical Sciences  Condensed matter  Morphological and genetic evidence for early Holocene cattle management in northeastern China Hucai Zhang, Johanna L.A. Paijmans, Fengqin Chang, Xiaohong Wu, Guangjie Chen, Chuzhao Lei, Xiujuan Yang, Zhenyi Wei, Daniel G. Bradley, Ludovic Orlando, Terry O'Connor and Michael Hofreiter The domestication of cattle took place during the early Holocene, independently in the Near East and in southern Asia. Here, Zhang et al. provide evidence for management of taurine cattle in northern China, an area not previously considered as an independent domestication centre. 08 November 2013 | doi: 10.1038/ncomms3755 Biological Sciences  Evolution  Palaeontology  Carbon isotope records reveal precise timing of enhanced Southern Ocean upwelling during the last deglaciation Giuseppe Siani, Elisabeth Michel, Ricardo De Pol-Holz, Tim DeVries, Frank Lamy, Mélanie Carel, Gulay Isguder, Fabien Dewilde and Anna Lourantou Upwelling of CO2 from the Southern Ocean may have played a key role in deglacial warming, but marine sediment studies are hindered by inaccurate chronologies. Siani et al. present new surface reservoir 14C ages derived from tephra and show that deglacial CO2 escape was synchronous with Antarctic warming. 08 November 2013 | doi: 10.1038/ncomms3758 Earth Sciences  Climate science  Oceanography  Probing single- to multi-cell level charge transport in Geobacter sulfurreducens DL-1 Xiaocheng Jiang, Jinsong Hu, Emily R. Petersen, Lisa A. Fitzgerald, Charles S. Jackan, Alexander M. Lieber, Bradley R. Ringeisen, Charles M. Lieber and Justin C. Biffinger Microbial fuels cells present a way of generating electricity using the natural metabolism of microorganisms. Here, the authors carry out single-cell current measurements of Geobacter sulfurreducens DL-1 to determine the upper limits of microbial fuel cell performance. 08 November 2013 | doi: 10.1038/ncomms3751 Biological Sciences  Biophysics  Biotechnology  Physical chemistry  In situ electron holography study of charge distribution in high-κ charge-trapping memory Y. Yao, C. Li, Z. L. Huo, M. Liu, C. X. Zhu, C. Z. Gu, X. F. Duan, Y. G. Wang, L. Gu and R. C. Yu Charge-trapping memory offers many advantages over existing data storage media, though the spatial distribution of charge remains elusive. Here, Yao et al. use electron holography to map its distribution in high-κ dielectric stacks under different applied bias. 08 November 2013 | doi: 10.1038/ncomms3764 Physical Sciences  Applied physics  Materials science  Nanotechnology  Involvement of parental imprinting in the antisense regulation of onco-miR-372-373 Yonatan Stelzer, Ido Sagi and Nissim Benvenisty The miR-372-3 cluster has a role in oncogenesis. In this study, by utilizing parthenogenetic induced pluripotent stem cells, that lack the paternal genome, Stelzer et al. report that these miR-372-3 are negatively regulated by a paternally imprinted antisense transcript and that loss of its expression promotes oncogenesis. 07 November 2013 | doi: 10.1038/ncomms3724 Biological Sciences  Cancer  Modern Antarctic acorn worms form tubes Kenneth M. Halanych, Johanna T. Cannon, Andrew R. Mahon, Billie J. Swalla and Craig R. Smith Acorn worms, or enteropneusts, are a group of hemichordates whose modern representatives are thought to be tubeless. Here, Halaynch et al. provide evidence for modern tube-forming acorn worms found in Antarctic benthic communities. 07 November 2013 | doi: 10.1038/ncomms3738 Biological Sciences  Evolution  Zoology  Surface tension and contact with soft elastic solids Robert W. Style, Callen Hyland, Rostislav Boltyanskiy, John S. Wettlaufer and Eric R. Dufresne Solid contacts on a microscopic level are widely described by a classical contact mechanics theory. Here, Style et al. show that this theory breaks down when a small particle adheres to a soft surface where a fluid-like behaviour is observed because of the predominant role played by surface tension. 07 November 2013 | doi: 10.1038/ncomms3728 Physical Sciences  Condensed matter  Materials science  Cavity cooling of free silicon nanoparticles in high vacuum OPEN Peter Asenbaum, Stefan Kuhn, Stefan Nimmrichter, Ugur Sezer and Markus Arndt Laser cooling has been a successful technique to cool atoms and diatomic molecules to very low temperatures. Here, using an external cavity for an improved light coupling, Asenbaum et al. achieve the cooling of much larger objects, silicon nanoparticles, and reduce their transverse kinetic energy by up to a factor of 30. 06 November 2013 | doi: 10.1038/ncomms3743 Physical Sciences  Nanotechnology  Optical physics  Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen Lorenza Favrot, Anna E. Grzegorzewicz, Daniel H. Lajiness, Rachel K. Marvin, Julie Boucau, Dragan Isailovic, Mary Jackson and Donald R. Ronning As drug-resistant strains of Mycobacterium tuberculosis continue to emerge, antitubercular drugs with novel mechanisms of action are in high demand. Here, the authors show that ebselen is an inhibitor of M. tuberculosis antigen 85 and reveal the mechanism of inhibition. 06 November 2013 | doi: 10.1038/ncomms3748 Biological Sciences  Microbiology  Experimental evolution of an alternating uni- and multicellular life cycle in Chlamydomonas reinhardtii OPEN William C. Ratcliff, Matthew D. Herron, Kathryn Howell, Jennifer T. Pentz, Frank Rosenzweig and Michael Travisano The early steps in the evolution of multicellularity are poorly understood. Here, Ratcliff et al. show that multicellularity can rapidly evolve in the green alga Chlamydomonas reinhardtii, demonstrating that single-cell developmental bottlenecks may evolve rapidly via co-option of the ancestral phenotype. 06 November 2013 | doi: 10.1038/ncomms3742 Biological Sciences  Evolution  Heterogeneous stacking of nanodot monolayers by dry pick-and-place transfer and its applications in quantum dot light-emitting diodes Tae-Ho Kim, Dae-Young Chung, JiYeon Ku, Inyong Song, Soohwan Sul, Dae-Hyeong Kim, Kyung-Sang Cho, Byoung Lyong Choi, Jong Min Kim, Sungwoo Hwang and Kinam Kim Several techniques exist for patterning a single densely packed layer of quantum dots onto a surface. Kim et al. now demonstrate a simple and reliable technique for transferring multiple monolayers, one-by-one, to form stacked multilayers of quantum dots of different types and sizes on a surface. 06 November 2013 | doi: 10.1038/ncomms3637 Physical Sciences  Applied physics  Materials science  Nanotechnology  Heterointerface engineered electronic and magnetic phases of NdNiO3 thin films Jian Liu, Mehdi Kargarian, Mikhail Kareev, Ben Gray, Phil J. Ryan, Alejandro Cruz, Nadeem Tahir, Yi-De Chuang, Jinghua Guo, James M. Rondinelli, John W. Freeland, Gregory A. Fiete and Jak Chakhalian The behaviour of strongly correlated nickelates is well studied in bulk but the corresponding strained thin films are largely unexplored. Here, the authors study strained NdNiO3 thin films with various degrees of strain and, in addition to a metal-to-insulator transition, find quantum critical behaviour. 06 November 2013 | doi: 10.1038/ncomms3714 Physical Sciences  Condensed matter  Materials science  Chimeric viruses blur the borders between the major groups of eukaryotic single-stranded DNA viruses Simon Roux, François Enault, Gisèle Bronner, Daniel Vaulot, Patrick Forterre and Mart Krupovic Single-stranded DNA viruses are almost ubiquitous and highly diverse. Here, the authors focus on small DNA viruses possessing chimeric genomes with RNA virus-like capsids, disentangling their complex evolutionary history, which challenges the current borders between major groups of eukaryotic ssDNA viruses. 06 November 2013 | doi: 10.1038/ncomms3700 Biological Sciences  Evolution  Virology    Nature Communications JOBS of the week Associate Professor The University of Nottingham Post-Doctoral Research Associate University of Arizona Research Associate University College London (UCL) UCD Research Fellow Level 1 or 2 University College Dublin PhD student KU Leuven - Belgium Group Leader positions The International Center for Infectiology Research (CIRI) Postdoctoral Researcher University of Southern California Postdoctoral Possition University of São Paulo - FAPESP Research Associates x 2 posts Newcastle University Postdoctoral Associate The Wistar Institute More Science jobs from Nature Communications EVENT Clinical Genomics 2014 28.01.14 Boston, USA More science events from       Latest Corrigendum     Corrigendum: Another rapid event in the carbon-14 content of tree rings Fusa Miyake, Kimiaki Masuda and Toshio Nakamura 07 November 2013 | doi: 10.1038/ncomms3747 Earth Sciences  Biogeochemistry  Climate science      Advertisement Choose Scientific Reports for fast, efficient, open access publishing  94% of authors said they are likely or very likely to recommend Scientific Reports to their colleagues* 91% of authors would publish in Scientific Reports again*  SUBMIT your paper today!  *Nature Publishing Group author survey, data correct as of September 2013   Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. 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