Wednesday, November 6, 2013

Leukemia - Table of Contents alert Volume 27 Issue 11

Leukemia

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TABLE OF CONTENTS

Volume 27, Issue 11 (November 2013)

In this issue
Original Articles
Letters to the Editor
Erratum

Also new
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Original Articles

Top

THERAPY

Effect of graft source on mismatched unrelated donor hemopoietic stem cell transplantation after reduced intensity conditioning

F Malard, S Fürst, M Loirat, P Chevallier, J El-Cheikh, T Guillaume, J Delaunay, S Le Gouill, P Moreau, D Blaise and M Mohty

Leukemia 2013 27: 2113-2117; advance online publication, June 11, 2013; 10.1038/leu.2013.170

Abstract | Full Text

ACUTE LEUKEMIAS

SYK regulates mTOR signaling in AML

J Carnevale, L Ross, A Puissant, V Banerji, R M Stone, D J DeAngelo, K N Ross and K Stegmaier

Leukemia 2013 27: 2118-2128; advance online publication, March 28, 2013; 10.1038/leu.2013.89

Abstract | Full Text

Mitochondrial energetic and AKT status mediate metabolic effects and apoptosis of metformin in human leukemic cells

S Scotland, E Saland, N Skuli, F de Toni, H Boutzen, E Micklow, I Sénégas, R Peyraud, L Peyriga, F Théodoro, E Dumon, Y Martineau, G Danet-Desnoyers, F Bono, C Rocher, T Levade, S Manenti, C Junot, J-C Portais, N Alet, C Récher, M A Selak, M Carroll and J-E Sarry

Leukemia 2013 27: 2129-2138; advance online publication, April 9, 2013; 10.1038/leu.2013.107

Abstract | Full Text

F14512, a polyamine-vectorized anti-cancer drug, currently in clinical trials exhibits a marked preclinical anti-leukemic activity

A Kruczynski, A Pillon, L Créancier, I Vandenberghe, B Gomes, V Brel, E Fournier, J-P Annereau, E Currie, Y Guminski, D Bonnet, C Bailly and N Guilbaud

Leukemia 2013 27: 2139-2148; advance online publication, April 9, 2013; 10.1038/leu.2013.108

Abstract | Full Text

Newly diagnosed adult AML and MPAL patients frequently show clonal residual hematopoiesis

C Fernandez, M C Santos-Silva, A López, S Matarraz, M Jara-Acevedo, J Ciudad, M L Gutierrez, M L Sánchez, C Salvador-Osuna, M J Berruezo, J Á Díaz-Arias, A M Palomo-Hernández, E Colado, N González, D Gallardo, A Asensio, R García-Sánchez, R Saldaña, C Cerveró, A Carboné-Bañeres, O Gutierrez and A Orfao

Leukemia 2013 27: 2149-2156; advance online publication, April 12, 2013; 10.1038/leu.2013.109

Abstract | Full Text

Bone marrow WT1 levels at diagnosis, post-induction and post-intensification in adult de novo AML

J F Nomdedéu, M Hoyos, M Carricondo, E Bussaglia, C Estivill, J Esteve, M Tormo, R Duarte, O Salamero, M P Q de Llano, A García, J Bargay, I Heras, J M Martí-Tutusaus, A Llorente, J M Ribera, D Gallardo, A Aventin, S Brunet and J Sierra On behalf of the CETLAM Group

Leukemia 2013 27: 2157-2164; advance online publication, April 15, 2013; 10.1038/leu.2013.111

Abstract | Full Text

The MLL recombinome of acute leukemias in 2013 OPEN

C Meyer, J Hofmann, T Burmeister, D Gröger, T S Park, M Emerenciano, M Pombo de Oliveira, A Renneville, P Villarese, E Macintyre, H Cavé, E Clappier, K Mass-Malo, J Zuna, J Trka, E De Braekeleer, M De Braekeleer, S H Oh, G Tsaur, L Fechina, V H J van der Velden, J J M van Dongen, E Delabesse, R Binato, M L M Silva, A Kustanovich, O Aleinikova, M H Harris, T Lund-Aho, V Juvonen, O Heidenreich, J Vormoor, W W L Choi, M Jarosova, A Kolenova, C Bueno, P Menendez, S Wehner, C Eckert, P Talmant, S Tondeur, E Lippert, E Launay, C Henry, P Ballerini, H Lapillone, M B Callanan, J M Cayuela, C Herbaux, G Cazzaniga, P M Kakadiya, S Bohlander, M Ahlmann, J R Choi, P Gameiro, D S Lee, J Krauter, P Cornillet-Lefebvre, G Te Kronnie, B W Schäfer, S Kubetzko, C N Alonso, U zur Stadt, R Sutton, N C Venn, S Izraeli, L Trakhtenbrot, H O Madsen, P Archer, J Hancock, N Cerveira, M R Teixeira, L Lo Nigro, A Möricke, M Stanulla, M Schrappe, L Sedék, T Szczepański, C M Zwaan, E A Coenen, M M van den Heuvel-Eibrink, S Strehl, M Dworzak, R Panzer-Grümayer, T Dingermann, T Klingebiel and R Marschalek

Leukemia 2013 27: 2165-2176; advance online publication, April 30, 2013; 10.1038/leu.2013.135

Abstract | Full Text

MYELODYSPLASIAS

Global H3K4me3 genome mapping reveals alterations of innate immunity signaling and overexpression of JMJD3 in human myelodysplastic syndrome CD34+ cells

Y Wei, R Chen, S Dimicoli, C Bueso-Ramos, D Neuberg, S Pierce, H Wang, H Yang, Y Jia, H Zheng, Z Fang, M Nguyen, I Ganan-Gomez, B Ebert, R Levine, H Kantarjian and G Garcia-Manero

Leukemia 2013 27: 2177-2186; advance online publication, March 29, 2013; 10.1038/leu.2013.91

Abstract | Full Text

CHRONIC MYELOPROLIFERATIVE NEOPLASIAS

A role for reactive oxygen species in JAK2V617F myeloproliferative neoplasm progression

C Marty, C Lacout, N Droin, J-P Le Couédic, V Ribrag, E Solary, W Vainchenker, J-L Villeval and I Plo

Leukemia 2013 27: 2187-2195; advance online publication, April 5, 2013; 10.1038/leu.2013.102

Abstract | Full Text

CHRONIC LYMPHOCYTIC LEUKEMIA

Distinct patterns of novel gene mutations in poor-prognostic stereotyped subsets of chronic lymphocytic leukemia: the case of SF3B1 and subset #2

J C Strefford, L-A Sutton, P Baliakas, A Agathangelidis, J Malčíková, K Plevova, L Scarfó, Z Davis, E Stalika, D Cortese, N Cahill, L B Pedersen, P F di Celle, T Tzenou, C Geisler, P Panagiotidis, A W Langerak, N Chiorazzi, S Pospisilova, D Oscier, F Davi, C Belessi, L Mansouri, P Ghia, K Stamatopoulos and R Rosenquist

Leukemia 2013 27: 2196-2199; advance online publication, April 5, 2013; 10.1038/leu.2013.98

Abstract | Full Text

Reduction of complement factor H binding to CLL cells improves the induction of rituximab-mediated complement-dependent cytotoxicity OPEN

S Hörl, Z Bánki, G Huber, A Ejaz, D Windisch, B Muellauer, E Willenbacher, M Steurer and H Stoiber

Leukemia 2013 27: 2200-2208; advance online publication, June 13, 2013; 10.1038/leu.2013.169

Abstract | Full Text

NORMAL HEMOPOIESIS

p190-B RhoGAP regulates the functional composition of the mesenchymal microenvironment

R Raman, R S Kumar, A Hinge, S Kumar, R Nayak, J Xu, K Szczur, J A Cancelas and M-D Filippi

Leukemia 2013 27: 2209-2219; advance online publication, April 8, 2013; 10.1038/leu.2013.103

Abstract | Full Text

SENSITIVITY AND RESISTANCE TO THERAPY

The novel arsenical Darinaparsin circumvents BRG1-dependent, HO-1-mediated cytoprotection in leukemic cells

N Garnier, L A Petruccelli, M F Molina, M Kourelis, S Kwan, Z Diaz, H M Schipper, A Gupta, S V del Rincon, K K Mann and W H Miller Jr

Leukemia 2013 27: 2220-2228; advance online publication, February 21, 2013; 10.1038/leu.2013.54

Abstract | Full Text

ANIMAL MODELS

Targeting oncogene expression to endothelial cells induces proliferation of the myelo-erythroid lineage by repressing the notch pathway

E Alghisi, M Distel, M Malagola, V Anelli, C Santoriello, L Herwig, A Krudewig, C V Henkel, D Russo and M C Mione

Leukemia 2013 27: 2229-2241; advance online publication, April 29, 2013; 10.1038/leu.2013.132

Abstract | Full Text

Letters to the Editor

Top

Consolidation with VTd significantly improves the complete remission rate and time to progression following VTd induction and single autologous stem cell transplantation in multiple myeloma

X Leleu, G Fouquet, B Hebraud, M Roussel, D Caillot, M L Chrétien, B Arnulf, R Szalat, L Garderet, L Benajiba, B Pegourie, C Regny, B Royer, A Caulier, A M Stoppa, S Garciaz, C Touzeau, C Chaleteix, J P Fermand, H A Loiseau, T Facon, M Attal and P Moreau on behalf of Intergroupe Francophone du Myélome (IFM)

Leukemia 2013 27: 2242-2244; advance online publication, April 5, 2013; 10.1038/leu.2013.101

Full Text

STAT3 mutations are frequent in CD30+ T-cell lymphomas and T-cell large granular lymphocytic leukemia

R S Ohgami, L Ma, J D Merker, B Martinez, J L Zehnder and D A Arber

Leukemia 2013 27: 2244-2247; advance online publication, April 8, 2013; 10.1038/leu.2013.104

Full Text

Highly variable clinical manifestations in a large family with a novel GATA2 mutation

P G N J Mutsaers, A A van de Loosdrecht, K Tawana, C Bödör, J Fitzgibbon and F H Menko

Leukemia 2013 27: 2247-2248; advance online publication, April 8, 2013; 10.1038/leu.2013.105

Full Text

NPMc+ and FLT3_ITD mutations cooperate in inducing acute leukaemia in a novel mouse model

M Mallardo, A Caronno, G Pruneri, P R Raviele, A Viale, P G Pelicci and E Colombo

Leukemia 2013 27: 2248-2251; advance online publication, April 15, 2013; 10.1038/leu.2013.114

Full Text

Cutaneous T cell lymphoma cells are targets for immune checkpoint ligand PD-L1-specific, cytotoxic T cells

S Munir, G H Andersen, A Woetmann, N Ødum, J C Becker and M H Andersen

Leukemia 2013 27: 2251-2253; advance online publication, April 18, 2013; 10.1038/leu.2013.118

Full Text

Anti-oxidant vitamin E prevents accumulation of imatinib-resistant BCR-ABL1 kinase mutations in CML-CP xenografts in NSG mice

M Nieborowska-Skorska, G Hoser, A Hochhaus, T Stoklosa and T Skorski

Leukemia 2013 27: 2253-2254; advance online publication, April 22, 2013; 10.1038/leu.2013.123

Full Text

Long-term follow-up of treatment with imatinib in eosinophilia-associated myeloid/lymphoid neoplasms with PDGFR rearrangements in blast phase

G Metzgeroth, J Schwaab, D Gosenca, A Fabarius, C Haferlach, A Hochhaus, N C P Cross, W-K Hofmann and A Reiter

Leukemia 2013 27: 2254-2256; advance online publication, April 25, 2013; 10.1038/leu.2013.129

Full Text

Long-term follow-up of ETV6–RUNX1 ALL reveals that NCI risk, rather than secondary genetic abnormalities, is the key risk factor

A Enshaei, C J Schwab, Z J Konn, C D Mitchell, S E Kinsey, R Wade, A Vora, C J Harrison and A V Moorman

Leukemia 2013 27: 2256-2259; advance online publication, May 2, 2013; 10.1038/leu.2013.136

Full Text

Early morbidity and mortality in childhood acute lymphoblastic leukemia with very high white blood cell count

G Vaitkeviciene, M Heyman, O G Jonsson, B Lausen, A Harila-Saari, M Stenmarker, M Taskinen, T Zvirblis, A Åsberg, L Groth-Pedersen, L Rageliene and K Schmiegelow

Leukemia 2013 27: 2259-2262; advance online publication, May 2, 2013; 10.1038/leu.2013.137

Full Text

Gossypol overcomes stroma-mediated resistance to the BCL2 inhibitor ABT-737 in chronic lymphocytic leukemia cells ex vivo

R Soderquist, D J P Bates, A V Danilov and A Eastman

Leukemia 2013 27: 2262-2264; advance online publication, May 3, 2013; 10.1038/leu.2013.138

Full Text

Genetic characterization of SF3B1 mutations in single chronic lymphocytic leukemia cells

X Wu, R C Tschumper and D F Jelinek

Leukemia 2013 27: 2264-2267; advance online publication, May 20, 2013; 10.1038/leu.2013.155

Full Text

Erratum

Top

Reduction of complement factor H binding to CLL cells improves the induction of rituximab-mediated complement-dependent cytotoxicity

S Hörl, Z Bánki, G Huber, A Ejaz, D Windisch, B Muellauer, E Willenbacher, M Steurer and H Stoiber

Leukemia 2013 27: 2268; 10.1038/leu.2013.230

Full Text

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