Thursday, November 7, 2013

Gene Therapy - Table of Contents alert Volume 20 Issue 11

Gene Therapy

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Just one of many high-quality articles from Frontiers in Genetics: 
Major channels involved in neuropsychiatric disorders and therapeutic perspectives (open access)
In this review, Diana Conte Camerino and colleagues report recent studies assessing the role of calcium, sodium, and potassium channels in BPD, schizophrenia, and autism spectrum disorders, and briefly summarize promising pharmacological strategies targeted on ion channels for the therapy of mental illness and related genetic tests.

TABLE OF CONTENTS

Volume 20, Issue 11 (November 2013)

In this issue
Mini Review
Original Articles
Short Communication

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Nature Collections
TCGA pan-cancer analysis


The Cancer Genome Atlas Pan-cancer initiative examines the similarities and differences among the genomic and cellular alterations found in the first dozen tumor types to be profiled by TCGA. This first look across cancer offers new tools in genomics and bioinformatics and the prospect of repurposing targeted therapies directed by the molecular pathology of the tumors in addition to their clinical classification.
 
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Mini Review

Top

Immunotherapy with gene-modified T cells: limiting side effects provides new challenges

H J Stauss and E C Morris

Gene Ther 2013 20: 1029-1032; advance online publication, June 27, 2013; 10.1038/gt.2013.34

Abstract | Full Text

Original Articles

Top

An armed oncolytic measles vaccine virus eliminates human hepatoma cells independently of apoptosis

J Lampe, S Bossow, T Weiland, I Smirnow, R Lehmann, W Neubert, M Bitzer and U M Lauer

Gene Ther 2013 20: 1033-1041; advance online publication, May 30, 2013; 10.1038/gt.2013.28

Abstract | Full Text

Virus-mimetic polyplex particles for systemic and inflammation-specific targeted delivery of large genetic contents

S Kang, K Lu, J Leelawattanachai, X Hu, S Park, T Park, I M Min and M M Jin

Gene Ther 2013 20: 1042-1052; advance online publication, June 13, 2013; 10.1038/gt.2013.29

Abstract | Full Text

Beneficial effects of selective HDL-raising gene transfer on survival, cardiac remodelling and cardiac function after myocardial infarction in mice OPEN

S C Gordts, I Muthuramu, E Nefyodova, F Jacobs, E Van Craeyveld and B De Geest

Gene Ther 2013 20: 1053-1061; advance online publication, June 13, 2013; 10.1038/gt.2013.30

Abstract | Full Text

hIFN-α gene modification augments human natural killer cell line anti-human hepatocellular carcinoma function

W Jiang, C Zhang, Z Tian and J Zhang

Gene Ther 2013 20: 1062-1069; advance online publication, June 13, 2013; 10.1038/gt.2013.31

Abstract | Full Text

Combination of HIF-1α gene transfection and HIF-1-activated bone marrow-derived angiogenic cell infusion improves burn wound healing in aged mice

J Du, L Liu, F Lay, Q Wang, C Dou, X Zhang, S M Hosseini, A Simon, D J Rees, A K Ahmed, R Sebastian, K Sarkar, S Milner, G P Marti, G L Semenza and J W Harmon

Gene Ther 2013 20: 1070-1076; advance online publication, June 20, 2013; 10.1038/gt.2013.32

Abstract | Full Text

Beneficial effects of parenteral GLP-1 delivery by cell therapy in insulin-deficient streptozotocin diabetic mice

S Vasu, R C Moffett, J T McCluskey, M H Hamid, N Irwin and P R Flatt

Gene Ther 2013 20: 1077-1084; advance online publication, June 20, 2013; 10.1038/gt.2013.33

Abstract | Full Text

Downregulation of Stat3 in melanoma: reprogramming the immune microenvironment as an anticancer therapeutic strategy

P U Emeagi, S Maenhout, N Dang, C Heirman, K Thielemans and K Breckpot

Gene Ther 2013 20: 1085-1092; advance online publication, June 27, 2013; 10.1038/gt.2013.35

Abstract | Full Text

Long-term efficacy of ciliary muscle gene transfer of three sFlt-1 variants in a rat model of laser-induced choroidal neovascularization

M El Sanharawi, E Touchard, R Benard, P Bigey, V Escriou, C Mehanna, M-C Naud, M Berdugo, J-C Jeanny and F Behar-Cohen

Gene Ther 2013 20: 1093-1103; advance online publication, June 27, 2013; 10.1038/gt.2013.36

Abstract | Full Text

Short Communication

Top

De-targeting by miR-143 decreases unwanted transgene expression in non-tumorigenic cells

F Kopp, M Schnoedt, R Haase, E Wagner, A Roidl and M Ogris

Gene Ther 2013 20: 1104-1109; advance online publication, June 27, 2013; 10.1038/gt.2013.37

Abstract | Full Text

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