TABLE OF CONTENTS | | | | Volume 109, Issue 10 (2507-2762) Published online 12 November 2013
| | In this issue Clinical Studies Translational Therapeutics Molecular Diagnostics Genetics and Genomics
Also new today Advance online publication
| | | | | Advertisement | | | | | Clinical Studies | Top | | Is it possible to improve the breaking bad news skills of residents when a relative is present? A randomised study I Merckaert, A Liénard, Y Libert, I Bragard, N Delvaux, A-M Etienne, S Marchal, J Meunier, C Reynaert, J-L Slachmuylder and D Razavi Br J Cancer 2013 109: 2507-2514; advance online publication, October 15, 2013; 10.1038/bjc.2013.615 Abstract | Full Text | | | | Validation of the Children’s International Mucositis Evaluation Scale (ChIMES) in paediatric cancer and SCT S Jacobs, C Baggott, R Agarwal, T Hesser, T Schechter, P Judd, D Tomlinson, J Beyene and L Sung Br J Cancer 2013 109: 2515-2522; advance online publication, October 15, 2013; 10.1038/bjc.2013.618 Abstract | Full Text | | | | Allogeneic stem cell transplantation for patients with advanced rhabdomyosarcoma: a retrospective assessment U Thiel, E Koscielniak, F Blaeschke, T G P Grunewald, M Badoglio, M A Diaz, C Paillard, A Prete, M Ussowicz, P Lang, F Fagioli, P Lutz, G Ehninger, P Schneider, A Santucci, P Bader, B Gruhn, M Faraci, P Antunovic, J Styczynski, W H Krüger, L Castagna, P Rohrlich, M Ouachée-Chardin, A Salmon, C Peters, M Bregni, S Burdach and On behalf of the Solid Tumour Working Party and the Paediatric Disease Working Party of the European Group for Blood and Marrow Transplantation Br J Cancer 2013 109: 2523-2532; advance online publication, October 22, 2013; 10.1038/bjc.2013.630 Abstract | Full Text | | | | Cost-effectiveness of sentinel lymph node biopsy vs inguinofemoral lymphadenectomy in women with vulval cancer A J Sutton, P Barton, S Sundar, C Meads, A N Rosenthal, P Baldwin, K Khan and T E Roberts Br J Cancer 2013 109: 2533-2547; advance online publication, October 15, 2013; 10.1038/bjc.2013.631 Abstract | Full Text | | | | The impact of prior platinum therapy on survival in patients with metastatic urothelial cancer receiving vinflunine L C Harshman, R Fougeray, T K Choueiri, F A Schutz, Y Salhi, J E Rosenberg and J Bellmunt Br J Cancer 2013 109: 2548-2553; advance online publication, October 15, 2013; 10.1038/bjc.2013.617 Abstract | Full Text | | | | Phase II trial of docetaxel, cisplatin and 5FU chemotherapy in locally advanced and metastatic penis cancer (CRUK/09/001) S Nicholson, E Hall, S J Harland, J D Chester, L Pickering, J Barber, T Elliott, A Thomson, S Burnett, C Cruickshank, B Carrington, R Waters and A Bahl Br J Cancer 2013 109: 2554-2559; advance online publication, October 29, 2013; 10.1038/bjc.2013.620 Abstract | Full Text | | | | A study to investigate dose escalation of doxorubicin in ABVD chemotherapy for Hodgkin lymphoma incorporating biomarkers of response and toxicity A Gibb, A Greystoke, M Ranson, K Linton, S Neeson, G Hampson, T Illidge, E Smith, C Dive, A Pettitt, A Lister, P Johnson and J Radford Br J Cancer 2013 109: 2560-2565; advance online publication, October 17, 2013; 10.1038/bjc.2013.605 Abstract | Full Text | | | | Phase II study of gemcitabine and bexarotene (GEMBEX) in the treatment of cutaneous T-cell lymphoma T Illidge, C Chan, N Counsell, S Morris, J Scarisbrick, D Gilson, B Popova, P Patrick, P Smith, S Whittaker and R Cowan Br J Cancer 2013 109: 2566-2573; advance online publication, October 17, 2013; 10.1038/bjc.2013.616 Abstract | Full Text | | | | A dose-escalating phase I of imatinib mesylate with fixed dose of metronomic cyclophosphamide in targeted olid tumours A Adenis, I Ray-Coquard, A Italiano, E Chauzit, B Bui-Nguyen, J-Y Blay, E Tresch-Bruneel, C Fournier, S Clisant, E Y Amela, P A Cassier, M Molimard and N Penel Br J Cancer 2013 109: 2574-2578; advance online publication, October 22, 2013; 10.1038/bjc.2013.648 Abstract | Full Text | | | | First-in-human Phase I study of EZN-4176, a locked nucleic acid antisense oligonucleotide to exon 4 of the androgen receptor mRNA in patients with castration-resistant prostate cancer D Bianchini, A Omlin, C Pezaro, D Lorente, R Ferraldeschi, D Mukherji, M Crespo, I Figueiredo, S Miranda, R Riisnaes, A Zivi, A Buchbinder, D E Rathkopf, G Attard, H I Scher, J de Bono and D C Danila Br J Cancer 2013 109: 2579-2586; advance online publication, October 29, 2013; 10.1038/bjc.2013.619 Abstract | Full Text | | Translational Therapeutics | Top | | Silencing NOTCH signaling causes growth arrest in both breast cancer stem cells and breast cancer cells S Suman, T P Das and C Damodaran Br J Cancer 2013 109: 2587-2596; advance online publication, October 15, 2013; 10.1038/bjc.2013.642 Abstract | Full Text | | | | Tumour hypoxia determines the potential of combining mTOR and autophagy inhibitors to treat mammary tumours E Seront, R Boidot, C Bouzin, O Karroum, B F Jordan, B Gallez, J-P Machiels and O Feron Br J Cancer 2013 109: 2597-2606; advance online publication, October 24, 2013; 10.1038/bjc.2013.644 Abstract | Full Text | | | | Preclinical validation of Aurora kinases-targeting drugs in osteosarcoma E Tavanti, V Sero, S Vella, M Fanelli, F Michelacci, L Landuzzi, G Magagnoli, R Versteeg, P Picci, C M Hattinger and M Serra Br J Cancer 2013 109: 2607-2618; advance online publication, October 15, 2013; 10.1038/bjc.2013.643 Abstract | Full Text | | | | A c-Met inhibitor increases the chemosensitivity of cancer stem cells to the irinotecan in gastric carcinoma M Yashiro, T Nishii, T Hasegawa, T Matsuzaki, T Morisaki, T Fukuoka and K Hirakawa Br J Cancer 2013 109: 2619-2628; advance online publication, October 15, 2013; 10.1038/bjc.2013.638 Abstract | Full Text | | Molecular Diagnostics | Top | | Intratumoral regulatory T cells upregulate immunosuppressive molecules in head and neck cancer patients H-B Jie, N Gildener-Leapman, J Li, R M Srivastava, S P Gibson, T L Whiteside and R L Ferris Br J Cancer 2013 109: 2629-2635; advance online publication, October 29, 2013; 10.1038/bjc.2013.645 Abstract | Full Text | | | | Tumour-suppressive microRNA-29s inhibit cancer cell migration and invasion by targeting laminin–integrin signalling in head and neck squamous cell carcinoma T Kinoshita, N Nohata, T Hanazawa, N Kikkawa, N Yamamoto, H Yoshino, T Itesako, H Enokida, M Nakagawa, Y Okamoto and N Seki Br J Cancer 2013 109: 2636-2645; advance online publication, October 3, 2013; 10.1038/bjc.2013.607 Abstract | Full Text | | | | MicroRNA profile: a promising ancillary tool for accurate renal cell tumour diagnosis R M Silva-Santos, P Costa-Pinheiro, A Luis, L Antunes, F Lobo, J Oliveira, R Henrique and C Jerónimo Br J Cancer 2013 109: 2646-2653; advance online publication, October 15, 2013; 10.1038/bjc.2013.552 Abstract | Full Text | | | | Deregulation of DNA-dependent protein kinase catalytic subunit contributes to human hepatocarcinogenesis development and has a putative prognostic value M Evert, M Frau, M L Tomasi, G Latte, M M Simile, M A Seddaiu, A Zimmermann, S Ladu, T Staniscia, S Brozzetti, G Solinas, F Dombrowski, F Feo, R M Pascale and D F Calvisi Br J Cancer 2013 109: 2654-2664; advance online publication, October 17, 2013; 10.1038/bjc.2013.606 Abstract | Full Text | | | | Prognostic impact of tumour-infiltrating immune cells on biliary tract cancer B Goeppert, L Frauenschuh, M Zucknick, A Stenzinger, M Andrulis, F Klauschen, K Joehrens, A Warth, M Renner, A Mehrabi, M Hafezi, A Thelen, P Schirmacher and W Weichert Br J Cancer 2013 109: 2665-2674; advance online publication, October 17, 2013; 10.1038/bjc.2013.610 Abstract | Full Text | | | | SILAC-based phosphoproteomics reveals an inhibitory role of KSR1 in p53 transcriptional activity via modulation of DBC1 H Zhang, Y Xu, A Filipovic, L C Lit, C-Y Koo, J Stebbing and G Giamas Br J Cancer 2013 109: 2675-2684; advance online publication, October 15, 2013; 10.1038/bjc.2013.628 Abstract | Full Text | | | | Nutlin-3 preferentially sensitises wild-type p53-expressing cancer cells to DR5-selective TRAIL over rhTRAIL A Meijer, F A E Kruyt, A G J van der Zee, H Hollema, P Le, K A ten Hoor, G M M Groothuis, W J Quax, E G E de Vries and S de Jong Br J Cancer 2013 109: 2685-2695; advance online publication, October 17, 2013; 10.1038/bjc.2013.636 Abstract | Full Text | | | | Variability in functional p53 reactivation by PRIMA-1Met/APR-246 in Ewing sarcoma D N T Aryee, S Niedan, J Ban, R Schwentner, K Muehlbacher, M Kauer, R Kofler and H Kovar Br J Cancer 2013 109: 2696-2704; advance online publication, October 15, 2013; 10.1038/bjc.2013.635 Abstract | Full Text | | | | Tumour-infiltrating CD8+ lymphocytes as an independent predictive factor for pathological complete response to primary systemic therapy in breast cancer A N Seo, H J Lee, E J Kim, H J Kim, M H Jang, H E Lee, Y J Kim, J H Kim and S Y Park Br J Cancer 2013 109: 2705-2713; advance online publication, October 15, 2013; 10.1038/bjc.2013.634 Abstract | Full Text | | | | MiR-221/-222 differentiate prognostic groups in advanced breast cancers and influence cell invasion N Falkenberg, N Anastasov, K Rappl, H Braselmann, G Auer, A Walch, M Huber, I Höfig, M Schmitt, H Höfler, M J Atkinson and M Aubele Br J Cancer 2013 109: 2714-2723; advance online publication, October 15, 2013; 10.1038/bjc.2013.625 Abstract | Full Text | | Genetics and Genomics | Top | | MicroRNA-based molecular classification of non-BRCA1/2 hereditary breast tumours M Tanic, E Andrés, S M Rodriguez-Pinilla, I Marquez-Rodas, M Cebollero-Presmanes, V Fernandez, A Osorio, J Benítez and B Martinez-Delgado Br J Cancer 2013 109: 2724-2734; advance online publication, October 8, 2013; 10.1038/bjc.2013.612 Abstract | Full Text | | | | ALK gene amplification is associated with poor prognosis in colorectal carcinoma P Bavi, Z Jehan, R Bu, S Prabhakaran, N Al-Sanea, F Al-Dayel, M Al-Assiri, T Al-Halouly, R Sairafi, S Uddin and K S Al-Kuraya Br J Cancer 2013 109: 2735-2743; advance online publication, October 15, 2013; 10.1038/bjc.2013.641 Abstract | Full Text | | | | DICER1 hotspot mutations in non-epithelial gonadal tumours L Witkowski, J Mattina, S Schönberger, M J Murray, D G Huntsman, J S Reis-Filho, W G McCluggage, J C Nicholson, N Coleman, G Calaminus, D T Schneider, J Arseneau, C J R Stewart and W D Foulkes Br J Cancer 2013 109: 2744-2750; advance online publication, October 17, 2013; 10.1038/bjc.2013.637 Abstract | Full Text | | | | Fulvestrant induces resistance by modulating GPER and CDK6 expression: implication of methyltransferases, deacetylases and the hSWI/SNF chromatin remodelling complex B Giessrigl, W M Schmidt, M Kalipciyan, M Jeitler, M Bilban, M Gollinger, S Krieger, W Jäger, R M Mader and G Krupitza Br J Cancer 2013 109: 2751-2762; advance online publication, October 29, 2013; 10.1038/bjc.2013.583 Abstract | Full Text | | | | Please note that you need to be a subscriber or site-licence holder to enjoy full-text access to British Journal of Cancer. 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