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TABLE OF CONTENTS
| 30 October 2013 | Volume 32, Issue 21 |  |  |  |  | Have you seen? Articles
Also new AOP | |  |  | | Advertisement |  | EMBO Transparent Process
TRANSPARENT - Referee reports published (without attribution) - No confidential comments
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FAST <1 week to a first decision and <1 month to complete peer-review >90% of published manuscripts undergo a single round of revision (taking on average 3 months) >95% invited revisions are published | | | |  |  | Have you seen? | Top |  |  |  |  The force and effect of cell proliferationTissue tension anisotropy determines the orientation of cell divisions by controlling epithelial cell elongation. Pedro Campinho and Carl-Philipp Heisenberg The EMBO Journal (2013), 32, 2783 - 2784; 10.1038/emboj.2013.225 Abstract | Full text | PDF | Related article Published online: 04 October 2013 |  |  |  |  RNAtomy of the Spliceosome’s heartA comprehensive map of RNA rearrangements in the active spliceosome offers an unprecedented view of the inner workings of pre-mRNA splicing. Sophie Bonnal and Juan Valcárcel The EMBO Journal (2013), 32, 2785 - 2787; 10.1038/emboj.2013.213 Abstract | Full text | PDF | Related article Published online: 24 September 2013 |  |  |  |  Usp16: key controller of stem cells in Down syndromeMolecular mechanisms of Down-Syndrome (DS)-associated pathologies remain scarce. A recent study identifies the deubiquitinase Usp16 as key epigenetic regulator for stem cell homeostasis in DS. Jin-chong Xu, Valina L Dawson and Ted M Dawson The EMBO Journal (2013), 32, 2788 - 2789; 10.1038/emboj.2013.220 Abstract | Full text | PDF | Related article Published online: 27 September 2013 |  | Articles | Top |  |  |  |  Differential proliferation rates generate patterns of mechanical tension that orient tissue growthIn addition to the Daschous-Fat-Dachs planar cell polarity pathway, cell divisions in the developing Drosophila wing are oriented by changes in cell shape caused by circumferential mechanical forces that arise from local differences in proliferation rates. Yanlan Mao, Alexander L Tournier, Andreas Hoppe, Lennart Kester, Barry J Thompson and Nicolas Tapon The EMBO Journal (2013), 32, 2790 - 2803; 10.1038/emboj.2013.197 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 10 September 2013 |  |  |  |  RNA structure analysis of human spliceosomes reveals a compact 3D arrangement of snRNAs at the catalytic coreA biochemical tour-de-force of RNA interactions integrates structural and genetic information to model the catalytic centre of the human spliceosome, offering insights into the precisely orchestrated RNA network at the heart of pre-mRNA splicing. Maria Anokhina, Sergey Bessonov, Zhichao Miao, Eric Westhof, Klaus Hartmuth and Reinhard Lührmann The EMBO Journal (2013), 32, 2804 - 2818; 10.1038/emboj.2013.198 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 03 September 2013 |  |  |  |  microRNA-17-92 cluster is a direct Nanog target and controls neural stem cell through Trp53inp1 EMBO OpenDirect control of the miRNA-17/92 cluster enables Nanog to restrain p53 activity and thus to maintain pluripotency in neural stem cells. Neha Garg, Agnese Po, Evelina Miele, Antonio Francesco Campese, Federica Begalli, Marianna Silvano, Paola Infante, Carlo Capalbo, Enrico De Smaele, Gianluca Canettieri, Lucia Di Marcotullio, Isabella Screpanti, Elisabetta Ferretti and Alberto Gulino The EMBO Journal (2013), 32, 2819 - 2832; 10.1038/emboj.2013.214 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 27 September 2013 |  |  |  |  A novel non-coding RNA lncRNA-JADE connects DNA damage signalling to histone H4 acetylationATM activation upon DNA damage induces the long non-coding RNA lncRNA-JADE, which associates with BRCA1 to stimulate expression of JADE1 and hence histone H4 acetylation. LncRNA-JADE is highly expressed in breast cancer and required for tumour growth in vivo. Guohui Wan, Xiaoxiao Hu, Yunhua Liu, Cecil Han, Anil K Sood, George A Calin, Xinna Zhang and Xiongbin Lu The EMBO Journal (2013), 32, 2833 - 2847; 10.1038/emboj.2013.221 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 04 October 2013 |  |  |  |  TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes EMBO OpenUbiquitin ligases of the distinct Cullin-RING ligase (CRL) and RING-between-RING (RBR) families physically and functionally interact, suggesting how RBR ligase auto-inhibition may be relieved in Ariadne-subfamily members. Ian R Kelsall, David M Duda, Jennifer L Olszewski, Kay Hofmann, Axel Knebel, Frédéric Langevin, Nicola Wood, Melanie Wightman, Brenda A Schulman and Arno F Alpi The EMBO Journal (2013), 32, 2848 - 2860; 10.1038/emboj.2013.209 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 27 September 2013 |  |  |  |  The THO complex component Thp2 counteracts telomeric R-loops and telomere shorteningTelomere association of the THO complex controls chromosome end processing and reveals the presence of RNA:DNA hybrid structures involving long-noncoding TERRA RNA. Verena Pfeiffer, Jérôme Crittin, Larissa Grolimund and Joachim Lingner The EMBO Journal (2013), 32, 2861 - 2871; 10.1038/emboj.2013.217 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 01 October 2013 |  |  |  |  A novel CsrA titration mechanism regulates fimbrial gene expression in Salmonella typhimuriumThe 5′-UTR of the fimAICDHF mRNA antagonizes the activity of the RNA binding protein CsrA by a novel post-translational titration mechanism to regulate fimbrial gene expression. Torsten Sterzenbach, Kim T Nguyen, Sean-Paul Nuccio, Maria G Winter, Christopher A Vakulskas, Steven Clegg, Tony Romeo and Andreas J Bäumler The EMBO Journal (2013), 32, 2872 - 2883; 10.1038/emboj.2013.206 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 20 September 2013 |  |  |  |  The MADS transcription factor XAL2/AGL14 modulates auxin transport during Arabidopsis root development by regulating PIN expressionThe XAL2/AGL14 transcription factor regulates the expression of several members of the auxin efflux family to control auxin gradients and root development in Arabidopsis. Adriana Garay-Arroyo, Enrique Ortiz-Moreno, María de la Paz Sánchez, Angus S Murphy, Berenice García-Ponce, Nayelli Marsch-Martínez, Stefan de Folter, Adriana Corvera-Poiré, Fabiola Jaimes-Miranda, Mario A Pacheco-Escobedo, Joseph G Dubrovsky, Soraya Pelaz and Elena R Álvarez-Buylla The EMBO Journal (2013), 32, 2884 - 2895; 10.1038/emboj.2013.216 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 11 October 2013 |  | Please note that you need to be a subscriber or site-licence holder to enjoy full-text access to The EMBO Journal. In order to do so, please purchase a subscription. You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/nams/svc/myaccount (You will need to log in to be recognised as a nature.com registrant). 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