Clinical Pharmacology and Therapeutics - Table of Contents alert Volume 94 Issue 3

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Download the Application Notes TABLE OF CONTENTS Volume 94, Issue 3 (September 2013) In this issue In This Issue Editorial News & Views Perspectives Translation CPIC Update CPIC Guidelines State of the Art Reviews Research Erratum Also new AOP Sign up for CPT: Pharmacometrics & Systems Pharmacology e-alerts Sign up for e-alerts Recommend to your library Web feed Subscribe Advertisement New content available each week!  Original Research - Reviews & Perspectives - Tutorials CPT: PSP publishes critical content covering the latest advances in quantitative methods as applied in pharmacology, physiology, and therapeutics in humans with a common focus on the application of these two areas on drug development. CPT: PSP is an online open access journal.    In This Issue Top In This Issue Clin Pharmacol Ther 2013 94: 277; 10.1038/clpt.2013.142 Full Text Editorial Top Reinventing Bioinnovation K I Kaitin and P K Honig Clin Pharmacol Ther 2013 94: 279-283; 10.1038/clpt.2013.129 Abstract | Full Text News & Views Top HIGHLIGHTS Clin Pharmacol Ther 2013 94: 284-285; 10.1038/clpt.2013.141 Full Text ASCPT NEWS Clin Pharmacol Ther 2013 94: 286-290; 10.1038/clpt.2013.132 Full Text Perspectives Top POINT/COUNTERPOINT Anecdotes from ITMAT: Building Capacity for Translational Science G A FitzGerald Clin Pharmacol Ther 2013 94: 291-296; 10.1038/clpt.2013.84 Full Text COMMENTARIES The PCAST Report on Pharmaceutical Innovation: Implications for the FDA J Woodcock Clin Pharmacol Ther 2013 94: 297-300; 10.1038/clpt.2013.88 Abstract | Full Text The PCAST Report: Impact and Implications for the Pharmaceutical Industry S A Morris, M Rosenblatt, J J Orloff, F Lewis-Hall and J Waldstreicher Clin Pharmacol Ther 2013 94: 300-302; 10.1038/clpt.2013.93 Abstract | Full Text Are Drug Labels Static or Dynamic? M J Seminerio and M J Ratain Clin Pharmacol Ther 2013 94: 302-304; 10.1038/clpt.2013.109 Abstract | Full Text CONFERENCE PROCEEDINGS Regulatory Review: How Do Agencies Ensure the Quality of Decision Making? L Liberti, N McAuslane, P Patel, A Breckenridge, H G Eichler and R Peterson Clin Pharmacol Ther 2013 94: 305-308; 10.1038/clpt.2013.127 Abstract | Full Text Legal Foundations of Adaptive Licensing K Oye, L G Baird, A Chia, S Hocking, P B Hutt, D Lee, L Norwalk and V Salvatore Clin Pharmacol Ther 2013 94: 309-311; 10.1038/clpt.2013.95 Abstract | Full Text LETTERS TO THE EDITOR Logistic Regression in Signal Detection: Another Piece Added to the Puzzle O Caster, G N Norén, D Madigan and A Bate Clin Pharmacol Ther 2013 94: 312; advance online publication, May 21, 2013; 10.1038/clpt.2013.107 Full Text Response to “Logistic Regression in Signal Detection: Another Piece Added to the Puzzle” R Harpaz, W DuMouchel, P LePendu, A Bauer-Mehren, P Ryan and N H Shah Clin Pharmacol Ther 2013 94: 313; advance online publication, June 12, 2013; 10.1038/clpt.2013.125 Full Text Translation Top Building a New Biomedical Ecosystem: Pfizer’s Centers for Therapeutic Innovation A C Patel and A J Coyle Clin Pharmacol Ther 2013 94: 314-316; advance online publication, May 3, 2013; 10.1038/clpt.2013.89 Full Text CPIC Update Top Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C19 Genotype and Clopidogrel Therapy: 2013 Update S A Scott, K Sangkuhl, C M Stein, J-S Hulot, J L Mega, D M Roden, T E Klein, M S Sabatine, J A Johnson and A R Shuldiner Clin Pharmacol Ther 2013 94: 317-323; advance online publication, May 22, 2013; 10.1038/clpt.2013.105 Abstract | Full Text CPIC Guidelines Top Clinical Pharmacogenetics Implementation Consortium Guidelines for HLA-B Genotype and Carbamazepine Dosing S G Leckband, J R Kelsoe, H M Dunnenberger, A L George, Jr, E Tran, R Berger, D J Müller, M Whirl-Carrillo, K E Caudle and M Pirmohamed Clin Pharmacol Ther 2013 94: 324-328; advance online publication, May 21, 2013; 10.1038/clpt.2013.103 Abstract | Full Text State of the Art Top Clinical Approval Success Rates for Investigational Cancer Drugs J A DiMasi, J M Reichert, L Feldman and A Malins Clin Pharmacol Ther 2013 94: 329-335; advance online publication, June 5, 2013; 10.1038/clpt.2013.117 Abstract | Full Text Defining “Innovativeness” in Drug Development: A Systematic Review A S Kesselheim, B Wang and J Avorn Clin Pharmacol Ther 2013 94: 336-348; advance online publication, May 30, 2013; 10.1038/clpt.2013.115 Abstract | Full Text The Future of Population-Based Postmarket Drug Risk Assessment: A Regulator’s Perspective T A Hammad, G A Neyarapally, S Iyasu, J A Staffa and G Dal Pan Clin Pharmacol Ther 2013 94: 349-358; advance online publication, June 5, 2013; 10.1038/clpt.2013.118 Abstract | Full Text Reviews Top Industry and Regulatory Performance in 2012: A Year in Review H M Dowden, R Jahn, T Catka, A Jonsson, E Michael, Y Miwa and W Zinkand Clin Pharmacol Ther 2013 94: 359-366; advance online publication, May 8, 2013; 10.1038/clpt.2013.91 Abstract | Full Text Bleeding Risk in Atrial Fibrillation Patients Taking Vitamin K Antagonists: Systematic Review and Meta-Analysis L C Lopes, F A Spencer, I Neumann, M Ventresca, S Ebrahim, Q Zhou, N Bhatnaga, S Schulman, J Eikelboom and G Guyatt Clin Pharmacol Ther 2013 94: 367-375; advance online publication, May 13, 2013; 10.1038/clpt.2013.99 Abstract | Full Text Challenges and Limitations in the Interpretation of Systematic Reviews: Making Sense of Clopidogrel and CYP2C19 Pharmacogenetics M J Sorich, T M Polasek and M D Wiese Clin Pharmacol Ther 2013 94: 376-382; advance online publication, May 13, 2013; 10.1038/clpt.2013.100 Abstract | Full Text Research Top ARTICLES Gemfibrozil Impairs Imatinib Absorption and Inhibits the CYP2C8-Mediated Formation of Its Main Metabolite A M Filppula, A Tornio, M Niemi, P J Neuvonen and J T Backman Clin Pharmacol Ther 2013 94: 383-393; advance online publication, May 8, 2013; 10.1038/clpt.2013.92 Abstract | Full Text A Meta-Analysis of CYP2D6 Metabolizer Phenotype and Metoprolol Pharmacokinetics C M Blake, E D Kharasch, M Schwab and P Nagele Clin Pharmacol Ther 2013 94: 394-399; advance online publication, May 9, 2013; 10.1038/clpt.2013.96 Abstract | Full Text CYP2A6 Genotype but not Age Determines Cotinine Half-Life in Infants and Children D A Dempsey, N C Sambol, P Jacob, III, E Hoffmann, R F Tyndale, E Fuentes-Afflick and N L Benowitz Clin Pharmacol Ther 2013 94: 400-406; advance online publication, May 29, 2013; 10.1038/clpt.2013.114 Abstract | Full Text A Forensic Analysis of Drug Targets From 2000 Through 2012 B Munos Clin Pharmacol Ther 2013 94: 407-411; advance online publication, June 12, 2013; 10.1038/clpt.2013.126 Abstract | Full Text Erratum Top ERRATUM: In Vitro Methods to Support Transporter Evaluation in Drug Discovery and Development Clin Pharmacol Ther 2013 94: 412; advance online publication, July 10, 2013; 10.1038/clpt.2013.130 Full Text Please note that you need to be a subscriber or site-license holder to enjoy full-text access to Clinical Pharmacology & Therapeutics. 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