The EMBO Journal - Table of Contents alert Volume 32 Issue 13

TABLE OF CONTENTS 03 July 2013 | Volume 32, Issue 13 Have you seen? Review Articles Also new AOP Sign up for e-alerts Recommend to your library Web feed Subscribe Advertisement EMBO Transparent Process TRANSPARENT - Referee reports published (without attribution) - No confidential comments FAIR - Referee cross-commenting for balanced decisions - Scooping protection during review and revision FAST - <1 week to a first decision and <1 month to complete peer-review - >90% of published manuscripts undergo a single round of revision (taking on average 3 months) - >95% invited revisions are published Have you seen? Top Supersize me—new insights into cortical expansion and gyration of the mammalian brain Distinct neural precursors in the developing brain of mouse and ferret regulate cortex size and folding Laboni Ghosh and Sebastian Jessberger The EMBO Journal (2013), 32, 1793 - 1795; 10.1038/emboj.2013.128 Abstract | Full text | PDF | Related article Published online: 31 May 2013 A new player in Pol II pausing Transcription factor M1BP defines a novel pathway that regulates promoter-proximal pausing at a specific set of constitutively expressed genes Nicholas J Fuda and John T Lis The EMBO Journal (2013), 32, 1796 - 1798; 10.1038/emboj.2013.138 Abstract | Full text | PDF | Related article Published online: 07 June 2013 A DIStinctively novel exoribonuclease that really likes U Dis3L2 constitutes a novel, uridylation-connected 3'–5' degradation pathway for cytoplasmic RNA in both yeast and mammals. Imed E Gallouzi and Jeffrey Wilusz The EMBO Journal (2013), 32, 1799 - 1801; 10.1038/emboj.2013.136 Abstract | Full text | PDF | Related article | Related article | Related article Published online: 11 June 2013 CRISPRs extending their reach: prokaryotic RNAi protein Cas9 recruited for gene regulation CRISPR systems not only defend bacteria from foreign DNA but also contribute to pathogenicity, by regulating endogenous gene expression to evade host innate immune responses. Nadja Heidrich and Jörg Vogel The EMBO Journal (2013), 32, 1802 - 1804; 10.1038/emboj.2013.141 Abstract | Full text | PDF | Related article Published online: 11 June 2013 Review Top Getting to the heart of the matter: long non-coding RNAs in cardiac development and disease This review highlights newly discovered long non-coding RNAs generalizing their critical contribution to mammalian cardiogenesis and congenital heart disease. Johanna C Scheuermann and Laurie A Boyer The EMBO Journal (2013), 32, 1805 - 1816; 10.1038/emboj.2013.134 Abstract | Full text | PDF Published online: 11 June 2013 Articles Top Regulation of cerebral cortex size and folding by expansion of basal progenitors  EMBO Open Basal progenitor cell proliferation is sufficient to increase brain cortical surface in rodents, but drives cortical folding only in naturally gyrencephalic species. Miki Nonaka-Kinoshita, Isabel Reillo, Benedetta Artegiani, Maria Ángeles Martínez-Martínez, Mark Nelson, Víctor Borrell and Federico Calegari The EMBO Journal (2013), 32, 1817 - 1828; 10.1038/emboj.2013.96 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 26 April 2013 Distinct mechanisms of transcriptional pausing orchestrated by GAGA factor and M1BP, a novel transcription factor A newly identified transcription factor promotes transient RNA polymerase II pausing at a subset of Drosophila genes that are specified by a distinct core promoter element. Jian Li and David S Gilmour The EMBO Journal (2013), 32, 1829 - 1841; 10.1038/emboj.2013.111 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 24 May 2013 The exoribonuclease Dis3L2 defines a novel eukaryotic RNA degradation pathway The exonuclease Dis3L2 acts independently of the exosome in a novel pathway for cytoplasmic RNA turnover, preferentially degrading oligo-uridylated substrates. Michal Malecki, Sandra C Viegas, Tiago Carneiro, Pawel Golik, Clémentine Dressaire, Miguel G Ferreira and Cecília M Arraiano The EMBO Journal (2013), 32, 1842 - 1854; 10.1038/emboj.2013.63 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 15 March 2013 Exonuclease hDIS3L2 specifies an exosome-independent 3′-5′ degradation pathway of human cytoplasmic mRNA Cytoplasmic mRNA turnover is thought to be governed by hXRN1 and the RNA exosome. The 3′-5′ exonuclease hDis3L2 defines a third physiological mRNA decay pathway, independent of the exosome and linked to hXRN1. Michal Lubas, Christian K Damgaard, Rafal Tomecki, Dominik Cysewski, Torben Heick Jensen and Andrzej Dziembowski The EMBO Journal (2013), 32, 1855 - 1868; 10.1038/emboj.2013.135 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 11 June 2013 Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline Loss of Tudor-domain protein Tdrkh leads to meiotic arrest and transposon activation in the mouse germline, concomitant with the appearance of extended 2′O-methylated RNA fragments, thus linking Tdrkh to primary piRNA biogenesis. Jonathan P Saxe, Mengjie Chen, Hongyu Zhao and Haifan Lin The EMBO Journal (2013), 32, 1869 - 1885; 10.1038/emboj.2013.121 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 28 May 2013 The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis  EMBO Open The presence and role of actin filaments in cell nuclei remains incompletely understood. A proteomics approach now reveals a highly distinct set of F-actin-binding proteins in the nucleus, including a novel kinesin family member. Matthias Samwer, Heinz-Jürgen Dehne, Felix Spira, Martin Kollmar, Daniel W Gerlich, Henning Urlaub and Dirk Görlich The EMBO Journal (2013), 32, 1886 - 1902; 10.1038/emboj.2013.108 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 31 May 2013 Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk This paper describes a novel and direct interplay of beta-catenin with crucial regulators of autophagy, establishing Wnt/β-catenin signals as central hub in the coordination of cellular proliferation and autophagy. Katy J Petherick, Ann C Williams, Jon D Lane, Paloma Ordóñez-Morán, Joerg Huelsken, Tracey J Collard, Helena JM Smartt, Jennifer Batson, Karim Malik, Chris Paraskeva and Alexander Greenhough The EMBO Journal (2013), 32, 1903 - 1916; 10.1038/emboj.2013.123 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 04 June 2013 Expression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in rats The debated role of astrocytes in amyotrophic lateral sclerosis (ALS) gains additional support from neurodegenerative phenotypes caused by astrocyte-restricted expression of mutant TDP-43 in transgenic rats. Jianbin Tong, Cao Huang, Fangfang Bi, Qinxue Wu, Bo Huang, Xionghao Liu, Fang Li, Hongxia Zhou and Xu-Gang Xia The EMBO Journal (2013), 32, 1917 - 1926; 10.1038/emboj.2013.122 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 28 May 2013 OPA1 promotes pH flashes that spread between contiguous mitochondria without matrix protein exchange  EMBO Open Mitochondrial fusion events and transient changes in matrix pH linked to membrane depolarization are found to underlie mitochondrial flashes, whose propagation may help equilibrate energy states between connected mitochondria. Jaime Santo-Domingo, Marta Giacomello, Damon Poburko, Luca Scorrano and Nicolas Demaurex The EMBO Journal (2013), 32, 1927 - 1940; 10.1038/emboj.2013.124 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 28 May 2013 The epigenetic regulator PLZF represses L1 retrotransposition in germ and progenitor cells Silencing of L1 retrotransposons via both DNA methylation and L1 mRNA binding is the primary function of the stress-regulated POK family transcription factor PLZF in stem cell maintenance. William Puszyk, Thomas Down, David Grimwade, Christine Chomienne, Rebecca J Oakey, Ellen Solomon and Fabien Guidez The EMBO Journal (2013), 32, 1941 - 1952; 10.1038/emboj.2013.118 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 31 May 2013 Direct interaction of FtsZ and MreB is required for septum synthesis and cell division in Escherichia coli MreB engages with the cell-wall synthesis machinery to regulate cell elongation in E. coli. Strikingly, MreB also connects cell-wall synthesis with the divisome during septum formation via direct interaction with the Z-ring protein FtsZ. Andrew K Fenton and Kenn Gerdes The EMBO Journal (2013), 32, 1953 - 1965; 10.1038/emboj.2013.129 Abstract | Full text | PDF | Supp. info. | Review Process File Published online: 11 June 2013 Please note that you need to be a subscriber or site-licence holder to enjoy full-text access to The EMBO Journal. In order to do so, please purchase a subscription. You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/nams/svc/myaccount (You will need to log in to be recognised as a nature.com registrant). For further technical assistance, please contact our registration department. For print subscription enquiries, please contact our subscription department. 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